JP2019537596A5 - - Google Patents

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Publication number
JP2019537596A5
JP2019537596A5 JP2019523672A JP2019523672A JP2019537596A5 JP 2019537596 A5 JP2019537596 A5 JP 2019537596A5 JP 2019523672 A JP2019523672 A JP 2019523672A JP 2019523672 A JP2019523672 A JP 2019523672A JP 2019537596 A5 JP2019537596 A5 JP 2019537596A5
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JP
Japan
Prior art keywords
theta
hexafluoropropan
trifluoromethyl
benzyl
carboxylate
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Application number
JP2019523672A
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English (en)
Japanese (ja)
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JP7042548B2 (ja
JP2019537596A (ja
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Priority claimed from PCT/US2017/061875 external-priority patent/WO2018093953A1/en
Publication of JP2019537596A publication Critical patent/JP2019537596A/ja
Publication of JP2019537596A5 publication Critical patent/JP2019537596A5/ja
Priority to JP2022035398A priority Critical patent/JP7350117B2/ja
Application granted granted Critical
Publication of JP7042548B2 publication Critical patent/JP7042548B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019523672A 2016-11-16 2017-11-15 Ｍａｇｌ阻害剤の結晶形態 Expired - Fee Related JP7042548B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022035398A JP7350117B2 (ja) 2016-11-16 2022-03-08 Ｍａｇｌ阻害剤の結晶形態

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662423126P 2016-11-16 2016-11-16
US62/423,126 2016-11-16
PCT/US2017/061875 WO2018093953A1 (en) 2016-11-16 2017-11-15 Crystalline forms of a magl inhibitor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022035398A Division JP7350117B2 (ja) 2016-11-16 2022-03-08 Ｍａｇｌ阻害剤の結晶形態

Publications (3)

Publication Number Publication Date
JP2019537596A JP2019537596A (ja) 2019-12-26
JP2019537596A5 true JP2019537596A5 (enExample) 2020-12-24
JP7042548B2 JP7042548B2 (ja) 2022-03-28

Family

ID=62145805

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JP2019523672A Expired - Fee Related JP7042548B2 (ja) 2016-11-16 2017-11-15 Ｍａｇｌ阻害剤の結晶形態
JP2022035398A Active JP7350117B2 (ja) 2016-11-16 2022-03-08 Ｍａｇｌ阻害剤の結晶形態

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JP2022035398A Active JP7350117B2 (ja) 2016-11-16 2022-03-08 Ｍａｇｌ阻害剤の結晶形態

Country Status (38)

Country Link
US (2) US11142517B2 (enExample)
EP (2) EP3964503B1 (enExample)
JP (2) JP7042548B2 (enExample)
KR (1) KR102508739B1 (enExample)
CN (2) CN115093382A (enExample)
AU (1) AU2017361257B2 (enExample)
BR (1) BR112019010003A2 (enExample)
CA (1) CA3043610A1 (enExample)
CL (1) CL2019001340A1 (enExample)
CO (1) CO2019005045A2 (enExample)
CR (1) CR20190242A (enExample)
CY (2) CY1124870T1 (enExample)
DK (1) DK3541807T3 (enExample)
DO (1) DOP2019000120A (enExample)
EA (1) EA201991086A1 (enExample)
EC (1) ECSP19035171A (enExample)
ES (2) ES2900016T3 (enExample)
GE (2) GEAP202315091A (enExample)
HR (2) HRP20211863T1 (enExample)
HU (2) HUE064559T2 (enExample)
IL (1) IL266548A (enExample)
JO (1) JOP20190109B1 (enExample)
LT (1) LT3541807T (enExample)
MA (2) MA46866B1 (enExample)
MX (2) MX389459B (enExample)
MY (1) MY199386A (enExample)
NI (1) NI201900053A (enExample)
PE (1) PE20191239A1 (enExample)
PH (1) PH12019501068A1 (enExample)
PL (2) PL3541807T3 (enExample)
PT (1) PT3541807T (enExample)
RS (2) RS65016B1 (enExample)
SI (1) SI3541807T1 (enExample)
SM (2) SMT202100675T1 (enExample)
TN (1) TN2019000151A1 (enExample)
UA (1) UA124585C2 (enExample)
WO (1) WO2018093953A1 (enExample)
ZA (1) ZA201903093B (enExample)

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JOP20190107A1 (ar) 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
AU2017361254B2 (en) 2016-11-16 2021-09-23 H. Lundbeck A/S. Pharmaceutical formulations
PE20191239A1 (es) 2016-11-16 2019-09-16 Abide Therapeutics Inc Formas cristalinas de un inhibidor de magl
US10927105B1 (en) 2017-05-23 2021-02-23 Lundbeck La Jolla Research Center, Inc. Pyrazole MAGL inhibitors
DK3630744T3 (da) 2017-05-23 2023-03-06 H Lundbeck As Pyrazol-magl-inhibitorer
UA126685C2 (uk) 2017-08-29 2023-01-11 Луннбек Ла-Холья Рісьоч Сенте, Інк. Сполуки, які є модуляторами magl, і способи їх отримання і застосування
EP3793547A4 (en) 2018-05-15 2021-11-17 H. Lundbeck A/S MAGL INHIBITORS
MX2021000549A (es) * 2018-07-19 2021-03-25 Pfizer Compuestos espiro heterociclicos como inhibidores de magl.
AU2019322538B2 (en) 2018-08-13 2021-09-30 F. Hoffmann-La Roche Ag New heterocyclic compounds as monoacylglycerol lipase inhibitors
PL3883936T3 (pl) 2018-11-22 2023-11-20 F. Hoffmann-La Roche Ag Nowe związki heterocykliczne
EP3914589A4 (en) * 2019-01-25 2022-11-30 H. Lundbeck A/S Methods of treating disease with magl inhibitors
WO2021097107A1 (en) * 2019-11-15 2021-05-20 Lundbeck La Jolla Research Center, Inc. Crystalline forms of a magl inhibitor
AU2021259496A1 (en) 2020-04-21 2022-11-10 H. Lundbeck A/S Synthesis of a monoacylglycerol lipase inhibitor
WO2023092079A1 (en) * 2021-11-19 2023-05-25 Bryant Cynthia W Use of cannabinoid compounds to treat gastrointestinal disorders
IL313987A (en) 2021-12-29 2024-08-01 Psy Therapeutics Inc Inhibiting monoacylglycerol lipase (magl)
IL316302A (en) 2022-05-04 2024-12-01 H Lundbeck As Crystalline form of 111333-hexafluoropro s-1-pyridazin-3-ylca azaspiro2.5octane-6- as a monoacylglycerol lipase inhibitor
CN117665187B (zh) * 2023-11-23 2024-08-16 宁波大红鹰药业股份有限公司 一种舒林酸中间体杂质的测定方法

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US10463753B2 (en) * 2016-02-19 2019-11-05 Lundbeck La Jolla Research Center, Inc. Radiolabeled monoacylglycerol lipase occupancy probe
JOP20190106A1 (ar) 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
JOP20190105A1 (ar) 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
PE20191239A1 (es) 2016-11-16 2019-09-16 Abide Therapeutics Inc Formas cristalinas de un inhibidor de magl
JOP20190107A1 (ar) 2016-11-16 2019-05-09 Lundbeck La Jolla Research Center Inc مثبطات أحادي أسيل جليسرول ليباز (magl)
AU2017361254B2 (en) 2016-11-16 2021-09-23 H. Lundbeck A/S. Pharmaceutical formulations

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