JP2018538292A5 - - Google Patents

Download PDF

Info

Publication number
JP2018538292A5
JP2018538292A5 JP2018529981A JP2018529981A JP2018538292A5 JP 2018538292 A5 JP2018538292 A5 JP 2018538292A5 JP 2018529981 A JP2018529981 A JP 2018529981A JP 2018529981 A JP2018529981 A JP 2018529981A JP 2018538292 A5 JP2018538292 A5 JP 2018538292A5
Authority
JP
Japan
Prior art keywords
alkyl
alkylene
cancer
solvate
moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2018529981A
Other languages
English (en)
Japanese (ja)
Other versions
JP6867652B2 (ja
JP2018538292A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2016/080453 external-priority patent/WO2017097986A1/en
Publication of JP2018538292A publication Critical patent/JP2018538292A/ja
Publication of JP2018538292A5 publication Critical patent/JP2018538292A5/ja
Application granted granted Critical
Publication of JP6867652B2 publication Critical patent/JP6867652B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2018529981A 2015-12-09 2016-12-09 癌療法のためのモノマレイミド官能化白金化合物 Expired - Fee Related JP6867652B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15198739.3 2015-12-09
EP15198739 2015-12-09
PCT/EP2016/080453 WO2017097986A1 (en) 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy

Publications (3)

Publication Number Publication Date
JP2018538292A JP2018538292A (ja) 2018-12-27
JP2018538292A5 true JP2018538292A5 (https=) 2020-01-23
JP6867652B2 JP6867652B2 (ja) 2021-05-12

Family

ID=54849106

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018529981A Expired - Fee Related JP6867652B2 (ja) 2015-12-09 2016-12-09 癌療法のためのモノマレイミド官能化白金化合物

Country Status (21)

Country Link
US (2) US10723748B2 (https=)
EP (1) EP3386997B1 (https=)
JP (1) JP6867652B2 (https=)
CN (1) CN108368143B (https=)
AU (1) AU2016367306B2 (https=)
CA (1) CA3004630A1 (https=)
CY (1) CY1124529T1 (https=)
DK (1) DK3386997T3 (https=)
ES (1) ES2898704T3 (https=)
HR (1) HRP20211466T1 (https=)
HU (1) HUE056897T2 (https=)
IL (1) IL259864B (https=)
LT (1) LT3386997T (https=)
MX (1) MX377528B (https=)
PL (1) PL3386997T3 (https=)
PT (1) PT3386997T (https=)
RS (1) RS62412B1 (https=)
SG (1) SG11201804885TA (https=)
SI (1) SI3386997T1 (https=)
SM (1) SMT202100709T1 (https=)
WO (1) WO2017097986A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3797768A1 (en) * 2014-06-23 2021-03-31 Placon Therapeutics, Inc. Maleimide-functionalised platinum for use in the treatment of cancer
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
CN109171001A (zh) * 2018-09-14 2019-01-11 上海烟草集团有限责任公司 草酸钠在降低卷烟烟气中TSNAs释放量中的应用
JP2023508996A (ja) * 2019-12-31 2023-03-06 キネート バイオファーマ インク. Cdk12/13阻害剤を用いる癌の処置
CN114163479B (zh) * 2020-09-11 2025-05-16 上海海聚生物科技有限公司 一类治疗癌症用的铂类化合物及其制备方法
US20230339997A1 (en) * 2020-09-11 2023-10-26 Shanghai Haiju Biological Technology Co., Ltd. Class of platinum compounds for treating cancer, and method for preparation thereof
CN114539320B (zh) * 2020-11-25 2026-01-27 北京大学 辐射激活的四价铂配合物及其用途

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CH605550A5 (https=) 1972-06-08 1978-09-29 Research Corp
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
EP0052322B1 (de) 1980-11-10 1985-03-27 Gersonde, Klaus, Prof. Dr. Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
DE3218121A1 (de) 1982-05-14 1983-11-17 Leskovar, Peter, Dr.-Ing., 8000 München Arzneimittel zur tumorbehandlung
EP0102324A3 (de) 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
JPS607934A (ja) 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソ−ムの製造方法
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
DE3483949D1 (de) 1983-09-26 1991-02-21 Udo Dr Med Ehrenfeld Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr.
EP0143949B1 (en) 1983-11-01 1988-10-12 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Pharmaceutical composition containing urokinase
CS269719B1 (en) 1986-12-29 1990-05-14 Kiss Frantisek Platinum cytostatic
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
DE19636889A1 (de) 1996-09-11 1998-03-12 Felix Dr Kratz Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel
CN1169520C (zh) 1997-09-29 2004-10-06 耐科塔医药公司 多孔微粒及其使用方法
CZ302070B6 (cs) 1998-04-21 2010-09-29 Micromet Ag Jednoretezcový multifunkcní polypeptid, polynukleotid, vektor obsahující tento polynukleotid, bunka transfekovaná tímto polynukleotidem, prostredek obsahující tento polypeptid, polynukleotid nebo vektor a jejich použití a zpusob identifikace aktiváto
DE19926154A1 (de) 1999-06-09 2000-12-14 Ktb Tumorforschungs Gmbh Verfahren zur Herstellung einer injizierbaren Arzneimittelzubereitung
AUPQ641100A0 (en) 2000-03-23 2000-04-15 Australia Nuclear Science & Technology Organisation Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
ES2525087T5 (es) 2000-05-10 2018-06-28 Novartis Ag Polvos basados en fosfolípidos para administración de fármacos
JP2005514393A (ja) 2001-12-19 2005-05-19 ネクター セラピューティクス アミノグリコシドの肺への供給
DE10314780A1 (de) 2003-03-19 2004-09-30 Ktb Tumorforschungsgesellschaft Mbh Proteinbindende Derivate von Platinkomplexen mit Cyclobutan-1,1-dicarboxylatliganden
HRP20050902A2 (en) 2003-03-31 2005-12-31 Pliva-Lachema A.S. Pharmaceutical composition containing platinum complex as active substance and method of manufacturing thereof
CZ2004945A3 (cs) 2004-09-08 2006-01-11 Pliva - Lachema A. S. Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ2004964A3 (cs) 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
US20060205810A1 (en) 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations
CZ300120B6 (cs) 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300424B6 (cs) 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
CZ300590B6 (cs) 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CN104244718A (zh) 2011-12-05 2014-12-24 伊格尼卡生物治疗公司 抗体-药物缀合物以及相关化合物、组合物和方法
CN117462693A (zh) * 2012-02-27 2024-01-30 阿穆尼克斯运营公司 Xten缀合组合物和制造其的方法
BR112016006955A2 (pt) * 2013-10-08 2017-08-01 Atlas Genetics Ltd compostos de marcação e seu uso em ensaios
US10011622B2 (en) 2013-12-31 2018-07-03 Placon Therapeutics, Inc. Compounds, compositions, and methods for the treatment of cancers
EP3797768A1 (en) * 2014-06-23 2021-03-31 Placon Therapeutics, Inc. Maleimide-functionalised platinum for use in the treatment of cancer
JP2018518509A (ja) * 2015-06-23 2018-07-12 プラコン セラピューティクス インコーポレイテッドPlacon Therapeutics,Inc. 白金化合物、組成物及びその使用
EP3313392B1 (en) 2015-06-23 2020-09-16 Placon Therapeutics, Inc. Platinum compounds, compositions, and uses thereof
EP3313527B1 (en) 2015-06-29 2021-02-24 Case Western Reserve University Anticancer drug-containing plant virus particles
FI3319936T3 (fi) 2015-07-12 2026-03-12 Hangzhou Dac Biotech Co Ltd Silloituslinkkereitä soluun sitoutuvien molekyylien konjugoimiseksi
US10639378B2 (en) 2016-06-06 2020-05-05 Genentech, Inc. Silvestrol antibody-drug conjugates and methods of use
WO2018009811A1 (en) 2016-07-08 2018-01-11 Genentech, Inc. Use of human epididymis protein 4 (he4) for assessing responsiveness of muc 16-positive cancer treatment
WO2018026742A1 (en) 2016-08-01 2018-02-08 Askgene Pharma Inc. Novel antibody-albumin-drug conjugates (aadc) and methods for using them
CN108164512B (zh) 2017-12-27 2021-05-25 沈阳药科大学 一类具有生物粘附作用的马来酰亚胺型前药及其在口服药物传递中的应用
CN108187063B (zh) 2018-01-09 2020-09-08 沈阳药科大学 白蛋白结合型抗肿瘤药-马来酰亚胺分子前药

Similar Documents

Publication Publication Date Title
JP2018538292A5 (https=)
JP2018138577A5 (https=)
JP2012505916A5 (https=)
JP2020525429A5 (https=)
JP2020533277A5 (https=)
JP2013522292A5 (https=)
JP2020518669A5 (https=)
JP2017530171A5 (https=)
JP2018511590A5 (https=)
RU2019121922A (ru) Композиции и способы лечения рака
NZ603654A (en) Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities
JP2019535744A5 (https=)
JP2020530487A5 (https=)
JP2019512478A5 (https=)
JP2019511483A5 (https=)
JP2019508496A5 (https=)
JP2014528480A5 (https=)
JP2017538677A5 (https=)
JP2016153410A5 (https=)
JP2017526662A5 (https=)
HRP20211466T1 (hr) Spojevi platine funkcionalizirani monomaleimidom, namijenjeni terapiji raka
JP2013520502A5 (https=)
JP2013539795A5 (https=)
JP2007515413A5 (https=)
JP2016503414A5 (https=)