JP2018534932A5 - - Google Patents
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- JP2018534932A5 JP2018534932A5 JP2018522662A JP2018522662A JP2018534932A5 JP 2018534932 A5 JP2018534932 A5 JP 2018534932A5 JP 2018522662 A JP2018522662 A JP 2018522662A JP 2018522662 A JP2018522662 A JP 2018522662A JP 2018534932 A5 JP2018534932 A5 JP 2018534932A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- activity
- ion
- small molecule
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022068158A JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
| JP2023193435A JP2024020382A (ja) | 2015-11-02 | 2023-11-14 | 条件的活性型ポリペプチド |
| JP2025185767A JP2026027333A (ja) | 2015-11-02 | 2025-11-04 | 条件的活性型ポリペプチド |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562249907P | 2015-11-02 | 2015-11-02 | |
| US62/249,907 | 2015-11-02 | ||
| USPCT/US2016/019242 | 2016-02-24 | ||
| PCT/US2016/019242 WO2016138071A1 (en) | 2015-02-24 | 2016-02-24 | Conditionally active biological proteins |
| PCT/US2016/049715 WO2017078839A1 (en) | 2015-11-02 | 2016-08-31 | Conditionally active polypeptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022068158A Division JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018534932A JP2018534932A (ja) | 2018-11-29 |
| JP2018534932A5 true JP2018534932A5 (https=) | 2019-10-10 |
| JP7064769B2 JP7064769B2 (ja) | 2022-05-11 |
Family
ID=58662272
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018522662A Active JP7064769B2 (ja) | 2015-11-02 | 2016-08-31 | 条件的活性型ポリペプチド |
| JP2022068158A Active JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
| JP2023193435A Pending JP2024020382A (ja) | 2015-11-02 | 2023-11-14 | 条件的活性型ポリペプチド |
| JP2025185767A Pending JP2026027333A (ja) | 2015-11-02 | 2025-11-04 | 条件的活性型ポリペプチド |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022068158A Active JP7390748B2 (ja) | 2015-11-02 | 2022-04-18 | 条件的活性型ポリペプチド |
| JP2023193435A Pending JP2024020382A (ja) | 2015-11-02 | 2023-11-14 | 条件的活性型ポリペプチド |
| JP2025185767A Pending JP2026027333A (ja) | 2015-11-02 | 2025-11-04 | 条件的活性型ポリペプチド |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11472876B2 (https=) |
| EP (1) | EP3371349A1 (https=) |
| JP (4) | JP7064769B2 (https=) |
| KR (2) | KR102714709B1 (https=) |
| CN (2) | CN115521374B (https=) |
| AU (2) | AU2016350613B2 (https=) |
| CA (1) | CA3003399A1 (https=) |
| MX (2) | MX2018005063A (https=) |
| RU (1) | RU2735023C9 (https=) |
| WO (1) | WO2017078839A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2913205T3 (es) * | 2014-05-13 | 2022-06-01 | Bioatla Inc | Proteínas biológicas activas condicionalmente |
| WO2017078839A1 (en) * | 2015-11-02 | 2017-05-11 | Bioatla, Llc | Conditionally active polypeptides |
| US10697972B2 (en) | 2016-01-12 | 2020-06-30 | Bioatla, Llc | Diagnostics using conditionally active antibodies |
| EP3403098B1 (en) * | 2016-01-12 | 2021-09-22 | BioAtla, Inc. | Diagnostics using conditionally active antibodies |
| US11446398B2 (en) | 2016-04-11 | 2022-09-20 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| AU2017320874B2 (en) * | 2016-08-31 | 2024-03-07 | Bioatla, Llc | Conditionally active polypeptides and methods of generating them |
| KR20250159733A (ko) | 2017-01-11 | 2025-11-11 | 브리스톨-마이어스 스큅 컴퍼니 | Psgl-1 길항제 및 그의 용도 |
| JP7280827B2 (ja) | 2017-01-18 | 2023-05-24 | エクスマ バイオテック コーポレイション | Axlまたはror2に対するキメラ抗原受容体およびその使用方法 |
| PE20250933A1 (es) | 2017-03-14 | 2025-04-02 | Five Prime Therapeutics Inc | Anticuerpos de union a vista a ph acido |
| BR112020019083A2 (pt) | 2018-03-21 | 2020-12-29 | Five Prime Therapeutics, Inc. | Anticorpos, ácido nucleico, composições, célula e métodos para preparar um anticorpo, para tratar câncer, para tratar uma doença infecciosa, para tratar uma inflamação, para a identificação de um anticorpo, para melhorar a eficácia antitumoral de um anticorpo, para melhorar a farmacocinética de um anticorpo, para selecionar um anticorpo, para melhorar a eficácia de anticorpos, para isolar anticorpos, para detectar vista em uma amostra e para tratar câncer |
| WO2019241216A1 (en) * | 2018-06-14 | 2019-12-19 | Bioatla, Llc | Multi-specific antibody constructs |
| PE20210687A1 (es) | 2018-07-11 | 2021-04-08 | Bristol Myers Squibb Co | Anticuerpos de union a vista a ph acido |
| WO2020041247A1 (en) * | 2018-08-21 | 2020-02-27 | Bioatla, Llc | CONDITIONALLY ACTIVE PROTEINS WITH pH SELECTIVITY |
| US12195544B2 (en) | 2018-09-21 | 2025-01-14 | Harpoon Therapeutics, Inc. | EGFR binding proteins and methods of use |
| CN113924118A (zh) | 2019-04-18 | 2022-01-11 | 百时美施贵宝公司 | 在低ph下具有增强的结合特异性的伊匹单抗变体 |
| US12391745B2 (en) * | 2020-06-15 | 2025-08-19 | Sarepta Therapeutics, Inc. | Adeno-associated virus antibodies and fragments thereof |
| EP4168452A4 (en) * | 2020-06-18 | 2024-07-10 | BioAtla, Inc. | Conditionally active anti-cd46 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| CN115768798A (zh) * | 2020-06-18 | 2023-03-07 | 生物蛋白有限公司 | 条件活性抗粘附分子-4(nectin-4)抗体 |
| EP4651894A2 (en) * | 2023-01-18 | 2025-11-26 | Harpoon Therapeutics, Inc. | Her2 targeting trispecific protein for treatment of cancer |
| JP2026507181A (ja) * | 2023-03-02 | 2026-02-27 | バイオアトラ インコーポレイテッド | 条件的活性型抗EpCAM抗体、抗体断片及びそれを組み込んだ構築物 |
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| US6573050B1 (en) * | 1999-10-29 | 2003-06-03 | Sunnybrook & Women's College Health Sciences Centre | Treatment, diagnosis and evaluation of anti-cancer therapy resistance in melanoma |
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| KR102276528B1 (ko) | 2011-09-30 | 2021-07-12 | 추가이 세이야쿠 가부시키가이샤 | 이온 농도 의존성 결합 분자 라이브러리 |
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| ES2913205T3 (es) | 2014-05-13 | 2022-06-01 | Bioatla Inc | Proteínas biológicas activas condicionalmente |
| WO2017078839A1 (en) * | 2015-11-02 | 2017-05-11 | Bioatla, Llc | Conditionally active polypeptides |
| AU2017320874B2 (en) * | 2016-08-31 | 2024-03-07 | Bioatla, Llc | Conditionally active polypeptides and methods of generating them |
-
2016
- 2016-08-31 WO PCT/US2016/049715 patent/WO2017078839A1/en not_active Ceased
- 2016-08-31 MX MX2018005063A patent/MX2018005063A/es unknown
- 2016-08-31 CA CA3003399A patent/CA3003399A1/en active Pending
- 2016-08-31 US US15/773,122 patent/US11472876B2/en active Active
- 2016-08-31 EP EP16862643.0A patent/EP3371349A1/en active Pending
- 2016-08-31 KR KR1020187014104A patent/KR102714709B1/ko active Active
- 2016-08-31 AU AU2016350613A patent/AU2016350613B2/en active Active
- 2016-08-31 RU RU2018115781A patent/RU2735023C9/ru active
- 2016-08-31 KR KR1020247032903A patent/KR20240150525A/ko active Pending
- 2016-08-31 CN CN202211275600.XA patent/CN115521374B/zh active Active
- 2016-08-31 CN CN201680077540.7A patent/CN108473555B/zh active Active
- 2016-08-31 JP JP2018522662A patent/JP7064769B2/ja active Active
-
2018
- 2018-04-24 MX MX2023001319A patent/MX2023001319A/es unknown
-
2022
- 2022-04-18 JP JP2022068158A patent/JP7390748B2/ja active Active
- 2022-08-19 US US17/820,913 patent/US20220403024A1/en active Pending
-
2023
- 2023-11-14 JP JP2023193435A patent/JP2024020382A/ja active Pending
- 2023-12-21 AU AU2023285915A patent/AU2023285915A1/en active Pending
-
2025
- 2025-11-04 JP JP2025185767A patent/JP2026027333A/ja active Pending
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