|
CA149387A
(en)
|
1913-05-22 |
1913-07-22 |
Andrew Jackson Coppock |
Means of priming explosive engines
|
|
CA151652A
(en)
|
1913-08-23 |
1913-11-11 |
Per Erik Martin Norell |
Side bearing for cars
|
|
CA157738A
(en)
|
1914-07-30 |
1914-09-08 |
John Martin Davis |
Aeroplane
|
|
DK100664C
(da)
|
1960-05-11 |
1964-12-21 |
Friedrich Tonne |
Rørpostanlæg med automatisk styring af rørpostpatronernes bevægelse.
|
|
US5436146A
(en)
|
1989-09-07 |
1995-07-25 |
The Trustees Of Princeton University |
Helper-free stocks of recombinant adeno-associated virus vectors
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5334761A
(en)
|
1992-08-28 |
1994-08-02 |
Life Technologies, Inc. |
Cationic lipids
|
|
US6133028A
(en)
|
1993-05-28 |
2000-10-17 |
Transgene S.A. |
Defective adenoviruses and corresponding complementation lines
|
|
ATE277640T1
(de)
|
1994-03-07 |
2004-10-15 |
Dow Chemical Co |
Bioaktive und/oder gezielte dendrimere-konjugate enthaltend genetisches material
|
|
CA2192442C
(en)
|
1994-06-10 |
2007-09-25 |
Imre Kovesdi |
Complementary adenoviral vector systems and cell lines
|
|
US5908635A
(en)
|
1994-08-05 |
1999-06-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method for the liposomal delivery of nucleic acids
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
US20020168342A1
(en)
|
1994-11-03 |
2002-11-14 |
Cell Genesys, Inc. |
Novel adenoviral vectors, packaging cell lines, recombinant adenoviruses and methods
|
|
IL116816A
(en)
|
1995-01-20 |
2003-05-29 |
Rhone Poulenc Rorer Sa |
Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
|
|
US5629184A
(en)
|
1995-01-25 |
1997-05-13 |
Amgen Inc. |
Cationic copolymers of vinylamine and vinyl alcohol for the delivery of oligonucleotides
|
|
FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
|
US5830430A
(en)
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
|
US6040183A
(en)
|
1995-06-07 |
2000-03-21 |
University Of North Carloina At Chapel Hill |
Helper virus-free AAV production
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
EP0844891A4
(en)
|
1995-08-11 |
2004-05-06 |
Dow Chemical Co |
HYPER COMBED POLYMER CONJUGATES
|
|
AU728220B2
(en)
|
1997-04-14 |
2001-01-04 |
Cell Genesys, Inc. |
Methods for increasing the efficiency of recombinant AAV product
|
|
US5948878A
(en)
|
1997-04-15 |
1999-09-07 |
Burgess; Stephen W. |
Cationic polymers for nucleic acid transfection and bioactive agent delivery
|
|
DE69840175D1
(de)
|
1997-12-12 |
2008-12-11 |
Samyang Corp |
Biologisch abbaubare gemischte polymerische mizellen zur genverabreichung
|
|
US6267987B1
(en)
|
1997-12-12 |
2001-07-31 |
Samyang Corporation |
Positively charged poly[alpha-(omega-aminoalkyl) glycolic acid] for the delivery of a bioactive agent via tissue and cellular uptake
|
|
US6169078B1
(en)
|
1998-05-12 |
2001-01-02 |
University Of Florida |
Materials and methods for the intracellular delivery of substances
|
|
BR9911062A
(pt)
|
1998-05-20 |
2001-02-06 |
Expression Genetics Inc |
Veìculo de gene polimérico de poli-l-lisina enxertado por polietileno glicol de direcionamento de hepatócito
|
|
US7030219B2
(en)
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
PT1537878E
(pt)
*
|
2002-07-03 |
2010-11-18 |
Ono Pharmaceutical Co |
Composições de imunopotenciação
|
|
JP2006502715A
(ja)
*
|
2002-10-11 |
2006-01-26 |
ザイモジェネティクス，インコーポレイティド |
ホモ３量体融合タンパク質の製造
|
|
US8512701B2
(en)
*
|
2002-11-15 |
2013-08-20 |
Morehouse School Of Medicine |
Anti-CXCL13 and anti-CXCR5 antibodies for the prevention and treatment of cancer and cancer cell migration
|
|
US7964194B2
(en)
*
|
2002-11-15 |
2011-06-21 |
Morehouse School Of Medicine |
Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation
|
|
AU2005316476A1
(en)
*
|
2004-12-15 |
2006-06-22 |
University Of Florida Research Foundation, Inc. |
Chimeric vectors
|
|
JP5364870B2
(ja)
*
|
2005-08-19 |
2013-12-11 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリン及びその使用
|
|
ES2657801T3
(es)
*
|
2007-07-10 |
2018-03-06 |
Apogenix Ag |
Proteínas de fusión de colectina de la superfamilia de TNF
|
|
WO2010037042A2
(en)
*
|
2008-09-26 |
2010-04-01 |
The General Hospital Corporation |
Methods for detecting and treating cancer
|
|
CN102282168A
(zh)
*
|
2008-11-18 |
2011-12-14 |
梅里麦克制药股份有限公司 |
人血清白蛋白接头以及其结合物
|
|
US20130017199A1
(en)
*
|
2009-11-24 |
2013-01-17 |
AMPLIMMUNE ,Inc. a corporation |
Simultaneous inhibition of pd-l1/pd-l2
|
|
CN102250254A
(zh)
*
|
2010-05-19 |
2011-11-23 |
江苏先声药物研究有限公司 |
肿瘤坏死因子相关凋亡诱导配体融合蛋白及其制备和应用
|
|
WO2012162426A1
(en)
*
|
2011-05-23 |
2012-11-29 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for heptameric targeting ligands
|
|
EP2714738B1
(en)
*
|
2011-05-24 |
2018-10-10 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
|
AU2012323937A1
(en)
*
|
2011-10-14 |
2014-06-05 |
Stc.Unm |
Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery including transdermal delivery of cargo and methods thereof
|
|
SI2776032T1
(sl)
|
2011-11-09 |
2018-12-31 |
Bristol-Myers Squibb Company |
Zdravljenje hematoloških malignih obolenj z anti-CXCR4 protitelesom
|
|
US9200072B2
(en)
*
|
2012-01-18 |
2015-12-01 |
Genentech Inc. |
Anti-LRP5 antibodies and methods of use
|
|
US9657082B2
(en)
|
2013-01-31 |
2017-05-23 |
Thomas Jefferson University |
PD-L1 and PD-L2-based fusion proteins and uses thereof
|
|
EP3030322A2
(en)
*
|
2013-08-05 |
2016-06-15 |
Cambridge Enterprise Limited |
Inhibition of cxcr4 signaling in cancer immunotherapy
|
|
US9290578B2
(en)
*
|
2013-10-21 |
2016-03-22 |
Genentech, Inc. |
Anti-Ly6E antibodies and methods of use
|
|
TWI681969B
(zh)
*
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對ｐｄ-１的人類抗體
|
|
EP3105246B1
(en)
*
|
2014-02-10 |
2021-03-31 |
Merck Patent GmbH |
Targeted tgf beta inhibition
|
|
CN105085677B
(zh)
*
|
2014-05-05 |
2019-01-18 |
中国科学院上海药物研究所 |
抗vegfr2人源纳米抗体ntv1及其制备方法和用途
|
|
US20170218091A1
(en)
*
|
2014-07-03 |
2017-08-03 |
Abbvie Inc. |
Monovalent binding proteins
|
|
PL3177640T3
(pl)
*
|
2014-08-08 |
2020-11-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Charakteryzujące się wysokim powinowactwem środki terapeutyczne naśladujące PD-11 i sposoby ich wykorzystania
|
|
ES2907486T3
(es)
*
|
2015-09-24 |
2022-04-25 |
Univ North Carolina Chapel Hill |
Métodos y composiciones para reducir metástasis
|
|
CN108079301B
(zh)
*
|
2016-11-23 |
2021-03-02 |
四川大学 |
减少cxcl13蛋白活性或表达量的活性物质在制备治疗恶性肿瘤转移药物中的用途
|
|
WO2018160572A1
(en)
*
|
2017-02-28 |
2018-09-07 |
Oncomed Pharmaceuticals, Inc. |
Methods for treatment of cancer comprising gitr-binding agents
|
|
KR20210043483A
(ko)
*
|
2018-03-05 |
2021-04-21 |
온코이뮨, 아이앤씨. |
후천성 면역 결핍 증후군(hiv/aids)을 치료하기 위한 가용성 cd24의 사용 방법
|
|
CN110357960A
(zh)
*
|
2018-04-10 |
2019-10-22 |
广州爱思迈生物医药科技有限公司 |
抗体及抗体改造方法
|
|
CN112870362B
(zh)
*
|
2021-02-08 |
2023-06-27 |
中山大学附属第一医院 |
Circ-MET-1214和/或Circ-M50作为靶点在制备抗肿瘤药物中的用途
|
|
CN113234165B
(zh)
*
|
2021-05-07 |
2023-02-28 |
暨南大学 |
EpCAM的改造的结合蛋白及其应用
|
|
CN113402618B
(zh)
*
|
2021-06-30 |
2022-06-10 |
徐州医科大学 |
Ski在制备增效型CAR-T细胞中的应用
|
|
CN113512115B
(zh)
*
|
2021-08-09 |
2023-09-15 |
江苏省农业科学院 |
一种广谱识别小菜蛾中肠受体的抗Cry2Aa独特型单域抗体及其应用
|