|
CA149387A
(en)
|
1913-05-22 |
1913-07-22 |
Andrew Jackson Coppock |
Means of priming explosive engines
|
|
CA151652A
(en)
|
1913-08-23 |
1913-11-11 |
Per Erik Martin Norell |
Side bearing for cars
|
|
CA157738A
(en)
|
1914-07-30 |
1914-09-08 |
John Martin Davis |
Aeroplane
|
|
DK100664C
(da)
|
1960-05-11 |
1964-12-21 |
Friedrich Tonne |
Rørpostanlæg med automatisk styring af rørpostpatronernes bevægelse.
|
|
US5436146A
(en)
|
1989-09-07 |
1995-07-25 |
The Trustees Of Princeton University |
Helper-free stocks of recombinant adeno-associated virus vectors
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5334761A
(en)
|
1992-08-28 |
1994-08-02 |
Life Technologies, Inc. |
Cationic lipids
|
|
US6133028A
(en)
|
1993-05-28 |
2000-10-17 |
Transgene S.A. |
Defective adenoviruses and corresponding complementation lines
|
|
MX9504664A
(es)
|
1994-03-07 |
1997-05-31 |
Dow Chemical Co |
Conjugados de dendrimeros bioactivos y/o dirigidos.
|
|
EP0784690B1
(en)
|
1994-06-10 |
2006-08-16 |
Genvec, Inc. |
Complementary adenoviral vector systems and cell lines
|
|
US5908635A
(en)
|
1994-08-05 |
1999-06-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method for the liposomal delivery of nucleic acids
|
|
US20020168342A1
(en)
|
1994-11-03 |
2002-11-14 |
Cell Genesys, Inc. |
Novel adenoviral vectors, packaging cell lines, recombinant adenoviruses and methods
|
|
US5872005A
(en)
|
1994-11-03 |
1999-02-16 |
Cell Genesys Inc. |
Packaging cell lines for adeno-associated viral vectors
|
|
IL116816A
(en)
|
1995-01-20 |
2003-05-29 |
Rhone Poulenc Rorer Sa |
Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
|
|
US5629184A
(en)
|
1995-01-25 |
1997-05-13 |
Amgen Inc. |
Cationic copolymers of vinylamine and vinyl alcohol for the delivery of oligonucleotides
|
|
FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
|
US5830430A
(en)
|
1995-02-21 |
1998-11-03 |
Imarx Pharmaceutical Corp. |
Cationic lipids and the use thereof
|
|
US6040183A
(en)
|
1995-06-07 |
2000-03-21 |
University Of North Carloina At Chapel Hill |
Helper virus-free AAV production
|
|
US6093570A
(en)
|
1995-06-07 |
2000-07-25 |
The University Of North Carolina At Chapel Hill |
Helper virus-free AAV production
|
|
WO1997006833A1
(en)
|
1995-08-11 |
1997-02-27 |
Dendritech, Inc. |
Hyper comb-branched polymer conjugates
|
|
EP1007637B1
(en)
|
1997-04-14 |
2004-06-30 |
Cell Genesys, Inc. |
Methods for increasing the efficiency of recombinant aav product
|
|
US5948878A
(en)
|
1997-04-15 |
1999-09-07 |
Burgess; Stephen W. |
Cationic polymers for nucleic acid transfection and bioactive agent delivery
|
|
CN1281355A
(zh)
|
1997-12-12 |
2001-01-24 |
三阳株式会社 |
用于基因递送的生物可降解性混合聚合胶束
|
|
WO1999029758A1
(en)
|
1997-12-12 |
1999-06-17 |
Samyang Corporation |
Positively-charged poly[alpha-(omega-aminoalkyl)glycolic acid] for the delivery of a bioactive agent via tissue and cellular uptake
|
|
US6169078B1
(en)
|
1998-05-12 |
2001-01-02 |
University Of Florida |
Materials and methods for the intracellular delivery of substances
|
|
CN1333678A
(zh)
|
1998-05-20 |
2002-01-30 |
表达遗传学公司 |
定向肝细胞的聚乙二醇接枝的聚-l-赖氨酸的聚合基因载体
|
|
US7030219B2
(en)
*
|
2000-04-28 |
2006-04-18 |
Johns Hopkins University |
B7-DC, Dendritic cell co-stimulatory molecules
|
|
DE60334303D1
(de)
*
|
2002-07-03 |
2010-11-04 |
Tasuku Honjo |
Immunpotenzierende zusammensetzungen
|
|
US20050009149A1
(en)
*
|
2002-10-11 |
2005-01-13 |
West James W. |
Production of homotrimeric fusion proteins
|
|
US8512701B2
(en)
*
|
2002-11-15 |
2013-08-20 |
Morehouse School Of Medicine |
Anti-CXCL13 and anti-CXCR5 antibodies for the prevention and treatment of cancer and cancer cell migration
|
|
US7964194B2
(en)
*
|
2002-11-15 |
2011-06-21 |
Morehouse School Of Medicine |
Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation
|
|
EP1828390B1
(en)
*
|
2004-12-15 |
2012-06-13 |
The University Of North Carolina At Chapel Hill |
Chimeric vectors
|
|
KR20140053410A
(ko)
*
|
2005-08-19 |
2014-05-07 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
|
EP2484691B1
(en)
|
2007-07-10 |
2016-01-13 |
Apogenix GmbH |
TNF superfamily collectin fusion proteins
|
|
WO2010037042A2
(en)
*
|
2008-09-26 |
2010-04-01 |
The General Hospital Corporation |
Methods for detecting and treating cancer
|
|
CN102282168A
(zh)
*
|
2008-11-18 |
2011-12-14 |
梅里麦克制药股份有限公司 |
人血清白蛋白接头以及其结合物
|
|
EP2504028A4
(en)
*
|
2009-11-24 |
2014-04-09 |
Amplimmune Inc |
SIMULTANEOUS INHIBITION OF PD-L1 / PD-L2
|
|
CN102250254A
(zh)
|
2010-05-19 |
2011-11-23 |
江苏先声药物研究有限公司 |
肿瘤坏死因子相关凋亡诱导配体融合蛋白及其制备和应用
|
|
WO2012162426A1
(en)
*
|
2011-05-23 |
2012-11-29 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for heptameric targeting ligands
|
|
DK2714738T3
(en)
|
2011-05-24 |
2019-01-28 |
Zyngenia Inc |
MULTIVALENT AND MONOVALENT MULTISPECIFIC COMPLEXES AND THEIR APPLICATIONS
|
|
US20150272885A1
(en)
*
|
2011-10-14 |
2015-10-01 |
Stc.Unm |
Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery including transdermal delivery of cargo and methods thereof
|
|
HUE043001T2
(hu)
*
|
2011-11-09 |
2019-07-29 |
Bristol Myers Squibb Co |
Hematológiai malignómák kezelése anti-CXCR4 antitesttel
|
|
SG10201601747XA
(en)
*
|
2012-01-18 |
2016-04-28 |
Genentech Inc |
Anti-LRP5 Antibodies And Methods Of Use
|
|
EP2950814A4
(en)
*
|
2013-01-31 |
2016-06-08 |
Univ Jefferson |
FUSION PROTEINS BASED ON PD-L1 AND PD-L2 AND USES THEREOF
|
|
EP3030322A2
(en)
*
|
2013-08-05 |
2016-06-15 |
Cambridge Enterprise Limited |
Inhibition of cxcr4 signaling in cancer immunotherapy
|
|
KR20160068963A
(ko)
*
|
2013-10-21 |
2016-06-15 |
제넨테크, 인크. |
항-Ly6E 항체 및 사용 방법
|
|
TWI681969B
(zh)
*
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
|
HRP20210977T1
(hr)
|
2014-02-10 |
2021-09-17 |
Merck Patent Gmbh |
Ciljano inhibiranje tgf beta
|
|
CN105085677B
(zh)
*
|
2014-05-05 |
2019-01-18 |
中国科学院上海药物研究所 |
抗vegfr2人源纳米抗体ntv1及其制备方法和用途
|
|
WO2016004389A2
(en)
*
|
2014-07-03 |
2016-01-07 |
Abbvie Inc. |
Monovalent binding proteins
|
|
EP3177640B1
(en)
|
2014-08-08 |
2020-05-06 |
The Board of Trustees of the Leland Stanford Junior University |
High affinity pd-1 agents and methods of use
|
|
US11219694B2
(en)
*
|
2015-09-24 |
2022-01-11 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for reducing metastases
|
|
CN108079301B
(zh)
|
2016-11-23 |
2021-03-02 |
四川大学 |
减少cxcl13蛋白活性或表达量的活性物质在制备治疗恶性肿瘤转移药物中的用途
|
|
WO2018160572A1
(en)
|
2017-02-28 |
2018-09-07 |
Oncomed Pharmaceuticals, Inc. |
Methods for treatment of cancer comprising gitr-binding agents
|
|
US20210046154A1
(en)
*
|
2018-03-05 |
2021-02-18 |
Oncoimmune, Inc |
Methods of use of soluble cd24 for treating acquired immune deficiency syndrome (hiv/aids)
|
|
CN110357960A
(zh)
*
|
2018-04-10 |
2019-10-22 |
广州爱思迈生物医药科技有限公司 |
抗体及抗体改造方法
|
|
CN112870362B
(zh)
*
|
2021-02-08 |
2023-06-27 |
中山大学附属第一医院 |
Circ-MET-1214和/或Circ-M50作为靶点在制备抗肿瘤药物中的用途
|
|
CN113234165B
(zh)
*
|
2021-05-07 |
2023-02-28 |
暨南大学 |
EpCAM的改造的结合蛋白及其应用
|
|
CN113402618B
(zh)
*
|
2021-06-30 |
2022-06-10 |
徐州医科大学 |
Ski在制备增效型CAR-T细胞中的应用
|
|
CN113512115B
(zh)
*
|
2021-08-09 |
2023-09-15 |
江苏省农业科学院 |
一种广谱识别小菜蛾中肠受体的抗Cry2Aa独特型单域抗体及其应用
|