JP2018532808A - 心血管疾患の処置のためのゲムカベンの組み合わせ - Google Patents
心血管疾患の処置のためのゲムカベンの組み合わせ Download PDFInfo
- Publication number
- JP2018532808A JP2018532808A JP2018543079A JP2018543079A JP2018532808A JP 2018532808 A JP2018532808 A JP 2018532808A JP 2018543079 A JP2018543079 A JP 2018543079A JP 2018543079 A JP2018543079 A JP 2018543079A JP 2018532808 A JP2018532808 A JP 2018532808A
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- Prior art keywords
- pharmaceutical composition
- gemcabene
- statin
- atorvastatin
- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562252195P | 2015-11-06 | 2015-11-06 | |
| US201562252147P | 2015-11-06 | 2015-11-06 | |
| US62/252,195 | 2015-11-06 | ||
| US62/252,147 | 2015-11-06 | ||
| PCT/US2016/060849 WO2017079755A1 (en) | 2015-11-06 | 2016-11-07 | Gemcabene combinations for the treatment of cardiovascular disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2018532808A true JP2018532808A (ja) | 2018-11-08 |
Family
ID=58663111
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018543079A Pending JP2018532808A (ja) | 2015-11-06 | 2016-11-07 | 心血管疾患の処置のためのゲムカベンの組み合わせ |
| JP2018543283A Pending JP2018536710A (ja) | 2015-11-06 | 2016-11-07 | 混合型脂質異常症の治療 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018543283A Pending JP2018536710A (ja) | 2015-11-06 | 2016-11-07 | 混合型脂質異常症の治療 |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US9849104B2 (enExample) |
| EP (2) | EP3370713A4 (enExample) |
| JP (2) | JP2018532808A (enExample) |
| KR (2) | KR20180073665A (enExample) |
| CN (2) | CN108366957A (enExample) |
| AU (2) | AU2016349634A1 (enExample) |
| BR (2) | BR112018009238A8 (enExample) |
| CA (2) | CA3001627A1 (enExample) |
| HK (2) | HK1257929A1 (enExample) |
| IL (2) | IL258819A (enExample) |
| MA (1) | MA43190A (enExample) |
| MX (2) | MX2018005540A (enExample) |
| PH (1) | PH12018500972A1 (enExample) |
| RU (2) | RU2018120599A (enExample) |
| SG (2) | SG11201803442UA (enExample) |
| WO (2) | WO2017079755A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| CA2949834A1 (en) | 2014-05-28 | 2015-12-03 | James Macormack Wells | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| CA2963704A1 (en) | 2014-10-17 | 2016-04-21 | Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
| SG10201912713YA (en) | 2014-11-14 | 2020-02-27 | Gemphire Therapeutics Inc | PROCESSES AND INTERMEDIATES FOR PREPARING α,ω-DICARBOXYLIC ACID-TERMINATED DIALKANE ETHERS |
| BR112018009238A8 (pt) * | 2015-11-06 | 2019-02-26 | Gemphire Therapeutics Inc | tratamento de dislipidemia mista |
| EP4177335A1 (en) | 2016-05-05 | 2023-05-10 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| KR20190039937A (ko) | 2016-07-08 | 2019-04-16 | 스태튼 바이오테크놀로지 비.브이. | 항-ApoC3 항체 및 이의 사용 방법 |
| KR102399254B1 (ko) | 2016-09-28 | 2022-05-17 | 아이거 바이오파마슈티컬스 인코포레이티드 | 비-알코올성 지방간염의 치료를 위한 방법 및 약제학적 조성물 |
| EP3534919A4 (en) | 2016-11-04 | 2020-11-11 | Children's Hospital Medical Center | Liver organoid compositions and methods of making and using same |
| KR20250068799A (ko) | 2016-12-05 | 2025-05-16 | 칠드런즈 호스피탈 메디칼 센터 | 결장 유사장기 및 이를 제조 및 사용하는 방법 |
| WO2018191673A1 (en) | 2017-04-14 | 2018-10-18 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| US20180297929A1 (en) * | 2017-04-18 | 2018-10-18 | Gemphire Therapeutics Inc. | Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor |
| CA3059133A1 (en) | 2017-04-21 | 2018-10-25 | Staten Biotechnology B.V. | Anti-apoc3 antibodies and methods of use thereof |
| US20180338922A1 (en) * | 2017-05-26 | 2018-11-29 | Esperion Therapeutics, Inc. | Fixed dose formulations |
| JP6937195B2 (ja) * | 2017-09-01 | 2021-09-22 | 興和株式会社 | 医薬組成物 |
| CA3077442A1 (en) | 2017-10-10 | 2019-04-18 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| MA50516A (fr) | 2017-10-31 | 2020-09-09 | Staten Biotechnology B V | Anticorps anti-apoc3 et leurs procédés d'utilisation |
| US10538583B2 (en) | 2017-10-31 | 2020-01-21 | Staten Biotechnology B.V. | Anti-APOC3 antibodies and compositions thereof |
| CA3082178A1 (en) * | 2017-11-28 | 2019-06-06 | Eiger Biopharmaceuticals, Inc. | Methods and pharmaceutical compositions for the treatment of non-alcoholic steatohepatitis |
| EP3727394A4 (en) | 2017-12-21 | 2021-09-08 | Children's Hospital Medical Center | DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF |
| US12421500B2 (en) | 2018-07-26 | 2025-09-23 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
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- 2016-11-07 HK HK19100291.5A patent/HK1257929A1/zh unknown
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