MX2018005096A - Combinaciones de gemcabeno para el tratamiento de enfermedad cardiovascular. - Google Patents
Combinaciones de gemcabeno para el tratamiento de enfermedad cardiovascular.Info
- Publication number
- MX2018005096A MX2018005096A MX2018005096A MX2018005096A MX2018005096A MX 2018005096 A MX2018005096 A MX 2018005096A MX 2018005096 A MX2018005096 A MX 2018005096A MX 2018005096 A MX2018005096 A MX 2018005096A MX 2018005096 A MX2018005096 A MX 2018005096A
- Authority
- MX
- Mexico
- Prior art keywords
- gemcabene
- combinations
- treatment
- cardiovascular disease
- cardiovascular
- Prior art date
Links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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- Epidemiology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Inorganic Chemistry (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
Abstract
La presente invención proporciona composiciones farmacéuticas formuladas para incluir una estatina y gemcabeno, donde la composición es útil para tratar, prevenir o reducir los síntomas de indicaciones cardiovasculares y metabólicas que implican elevar los niveles de colesterol LDL, triglicéridos o ambos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562252195P | 2015-11-06 | 2015-11-06 | |
US201562252147P | 2015-11-06 | 2015-11-06 | |
PCT/US2016/060849 WO2017079755A1 (en) | 2015-11-06 | 2016-11-07 | Gemcabene combinations for the treatment of cardiovascular disease |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018005096A true MX2018005096A (es) | 2018-08-15 |
Family
ID=58663111
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018005096A MX2018005096A (es) | 2015-11-06 | 2016-11-07 | Combinaciones de gemcabeno para el tratamiento de enfermedad cardiovascular. |
MX2018005540A MX2018005540A (es) | 2015-11-06 | 2016-11-07 | Tratamiento de dislipemia mixta. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018005540A MX2018005540A (es) | 2015-11-06 | 2016-11-07 | Tratamiento de dislipemia mixta. |
Country Status (16)
Country | Link |
---|---|
US (4) | US9849104B2 (es) |
EP (2) | EP3370703A4 (es) |
JP (2) | JP2018536710A (es) |
KR (2) | KR20180073597A (es) |
CN (2) | CN108348491A (es) |
AU (2) | AU2016349634A1 (es) |
BR (2) | BR112018009238A8 (es) |
CA (2) | CA3000016A1 (es) |
HK (2) | HK1257929A1 (es) |
IL (2) | IL258819A (es) |
MA (1) | MA43190A (es) |
MX (2) | MX2018005096A (es) |
PH (1) | PH12018500972A1 (es) |
RU (2) | RU2018120599A (es) |
SG (2) | SG10201912754UA (es) |
WO (2) | WO2017079748A1 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
EP3712254A1 (en) | 2014-05-28 | 2020-09-23 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のin vivoモデル、並びにそれを作製、及び使用する方法 |
CN111704543A (zh) | 2014-11-14 | 2020-09-25 | 燿石治疗公司 | 用于制备α,ω-二羧酸封端的二烷醚的方法和中间体 |
RU2018120599A (ru) * | 2015-11-06 | 2019-12-09 | Джемфир Терапьютикс, Инк. | Лечение смешанной дислипидемии |
WO2017192997A1 (en) | 2016-05-05 | 2017-11-09 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
CN109689685A (zh) | 2016-07-08 | 2019-04-26 | 斯塔滕生物技术有限公司 | 抗apoc3抗体及其使用方法 |
US10588880B2 (en) | 2016-09-28 | 2020-03-17 | Eiger Biopharmaceuticals, Inc. | Methods and pharmaceutical compositions for the treatment of non-alcoholic steatohepatitis |
US20200056157A1 (en) | 2016-11-04 | 2020-02-20 | Children's Hospital Medical Center | Liver organoid disease models and methods of making and using same |
KR102558606B1 (ko) | 2016-12-05 | 2023-07-26 | 칠드런즈 호스피탈 메디칼 센터 | 결장 유사장기 및 이를 제조 및 사용하는 방법 |
TW201902471A (zh) * | 2017-04-18 | 2019-01-16 | 美商珍費爾醫療公司 | 賈卡賓尼(gemcabene)、其醫藥上可接受之鹽、彼等之組成物及使用彼等之方法 |
WO2018193427A1 (en) | 2017-04-21 | 2018-10-25 | Staten Biotechnology B.V. | Anti-apoc3 antibodies and methods of use thereof |
US20180338922A1 (en) * | 2017-05-26 | 2018-11-29 | Esperion Therapeutics, Inc. | Fixed dose formulations |
JP6937195B2 (ja) * | 2017-09-01 | 2021-09-22 | 興和株式会社 | 医薬組成物 |
US10538583B2 (en) | 2017-10-31 | 2020-01-21 | Staten Biotechnology B.V. | Anti-APOC3 antibodies and compositions thereof |
SG11202003980PA (en) | 2017-10-31 | 2020-05-28 | Staten Biotechnology B V | Anti-apoc3 antibodies and methods of use thereof |
EP3716975A4 (en) * | 2017-11-28 | 2022-01-12 | Eiger Biopharmaceuticals, Inc. | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS |
WO2020077186A1 (en) * | 2018-10-12 | 2020-04-16 | Icahn School Of Medicine At Mount Sinai | Azd3355 (lesogaberan) for treatment and prevention of nonalcoholic steatohepatitis (nash), liver fibrosis, and other liver conditions |
JP2022505033A (ja) * | 2018-10-18 | 2022-01-14 | ジェムフィアー セラピューティクス インコーポレイテッド | ゲムカベン、薬学的に許容されるその塩、その組成物、およびその使用方法 |
CN112851660B (zh) * | 2019-11-12 | 2022-03-18 | 广东药科大学 | 含有小檗碱的酸-碱加成盐、其制备方法及其作为药物的用途 |
CN114957119B (zh) * | 2022-05-05 | 2023-06-16 | 武汉大学中南医院 | 一种四氢喹啉螺1,3-茚二酮类衍生物及其制备方法与应用 |
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