|
EP2689019A2
(en)
|
2011-03-23 |
2014-01-29 |
Pioneer Hi-Bred International Inc. |
Methods for producing a complex transgenic trait locus
|
|
WO2013066438A2
(en)
|
2011-07-22 |
2013-05-10 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
US10760064B2
(en)
|
2013-03-15 |
2020-09-01 |
The General Hospital Corporation |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
|
|
US10378027B2
(en)
|
2013-03-15 |
2019-08-13 |
The General Hospital Corporation |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci
|
|
DK2986729T3
(en)
|
2013-04-16 |
2018-10-29 |
Regeneron Pharma |
TARGETED MODIFICATION OF ROOT THROUGH
|
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
|
CA3221516A1
(en)
|
2013-08-22 |
2015-02-26 |
E. I. Du Pont De Nemours And Company |
Plant genome modification using guide rna/cas endonuclease systems and methods of use
|
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
|
US9340799B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
MRNA-sensing switchable gRNAs
|
|
US9388430B2
(en)
|
2013-09-06 |
2016-07-12 |
President And Fellows Of Harvard College |
Cas9-recombinase fusion proteins and uses thereof
|
|
US9526784B2
(en)
|
2013-09-06 |
2016-12-27 |
President And Fellows Of Harvard College |
Delivery system for functional nucleases
|
|
WO2015088643A1
(en)
|
2013-12-11 |
2015-06-18 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for the targeted modification of a genome
|
|
US20150166984A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting alpha-antitrypsin point mutations
|
|
WO2016022363A2
(en)
|
2014-07-30 |
2016-02-11 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
BR112017003757A2
(pt)
|
2014-09-12 |
2017-12-26 |
Du Pont |
?plantas de milho, partes de planta de milho ou sementes de milho?
|
|
AU2015330699B2
(en)
|
2014-10-10 |
2021-12-02 |
Editas Medicine, Inc. |
Compositions and methods for promoting homology directed repair
|
|
GB201418965D0
(enExample)
|
2014-10-24 |
2014-12-10 |
Ospedale San Raffaele And Fond Telethon |
|
|
WO2016073990A2
(en)
|
2014-11-07 |
2016-05-12 |
Editas Medicine, Inc. |
Methods for improving crispr/cas-mediated genome-editing
|
|
SI3250691T1
(sl)
|
2015-01-28 |
2023-10-30 |
Caribou Biosciences, Inc. |
Hibridni dna/rna-polinukleotidi crispr in postopki za uporabo
|
|
EP3553178A1
(en)
|
2015-03-27 |
2019-10-16 |
E. I. du Pont de Nemours and Company |
Soybean u6 small nuclear rna gene promoters and their use in constitutive expression of small rna genes in plants
|
|
GB201506509D0
(en)
|
2015-04-16 |
2015-06-03 |
Univ Wageningen |
Nuclease-mediated genome editing
|
|
EP3294896A1
(en)
|
2015-05-11 |
2018-03-21 |
Editas Medicine, Inc. |
Optimized crispr/cas9 systems and methods for gene editing in stem cells
|
|
KR102796744B1
(ko)
|
2015-06-09 |
2025-04-15 |
에디타스 메디신, 인코포레이티드 |
이식의 개선을 위한 crispr/cas-관련 방법 및 조성물
|
|
US20160362667A1
(en)
*
|
2015-06-10 |
2016-12-15 |
Caribou Biosciences, Inc. |
CRISPR-Cas Compositions and Methods
|
|
US10648020B2
(en)
|
2015-06-18 |
2020-05-12 |
The Broad Institute, Inc. |
CRISPR enzymes and systems
|
|
US9790490B2
(en)
*
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
|
CA2990699A1
(en)
|
2015-06-29 |
2017-01-05 |
Ionis Pharmaceuticals, Inc. |
Modified crispr rna and modified single crispr rna and uses thereof
|
|
WO2017004279A2
(en)
|
2015-06-29 |
2017-01-05 |
Massachusetts Institute Of Technology |
Compositions comprising nucleic acids and methods of using the same
|
|
US9512446B1
(en)
|
2015-08-28 |
2016-12-06 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
US9926546B2
(en)
|
2015-08-28 |
2018-03-27 |
The General Hospital Corporation |
Engineered CRISPR-Cas9 nucleases
|
|
EP3353296B1
(en)
|
2015-09-24 |
2020-11-04 |
Editas Medicine, Inc. |
Use of exonucleases to improve crispr/cas-mediated genome editing
|
|
SG10202104041PA
(en)
|
2015-10-23 |
2021-06-29 |
Harvard College |
Nucleobase editors and uses thereof
|
|
EP3350327B1
(en)
|
2015-10-23 |
2018-09-26 |
Caribou Biosciences, Inc. |
Engineered crispr class 2 cross-type nucleic-acid targeting nucleic acids
|
|
DK3371310T3
(da)
*
|
2015-12-04 |
2019-08-05 |
Caribou Biosciences Inc |
Nucleinsyrekonstruerede targetnucleinsyrer
|
|
CA3007635A1
(en)
|
2015-12-07 |
2017-06-15 |
Zymergen Inc. |
Promoters from corynebacterium glutamicum
|
|
WO2017100343A1
(en)
|
2015-12-07 |
2017-06-15 |
Arc Bio, Llc |
Methods and compositions for the making and using of guide nucleic acids
|
|
US9988624B2
(en)
|
2015-12-07 |
2018-06-05 |
Zymergen Inc. |
Microbial strain improvement by a HTP genomic engineering platform
|
|
US11208649B2
(en)
|
2015-12-07 |
2021-12-28 |
Zymergen Inc. |
HTP genomic engineering platform
|
|
US11845933B2
(en)
|
2016-02-03 |
2023-12-19 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide RNA and its applications
|
|
US9896696B2
(en)
|
2016-02-15 |
2018-02-20 |
Benson Hill Biosystems, Inc. |
Compositions and methods for modifying genomes
|
|
US11597924B2
(en)
|
2016-03-25 |
2023-03-07 |
Editas Medicine, Inc. |
Genome editing systems comprising repair-modulating enzyme molecules and methods of their use
|
|
WO2017180694A1
(en)
|
2016-04-13 |
2017-10-19 |
Editas Medicine, Inc. |
Cas9 fusion molecules gene editing systems, and methods of use thereof
|
|
SG11201810179RA
(en)
|
2016-04-19 |
2018-12-28 |
Broad Inst Inc |
Novel crispr enzymes and systems
|
|
CN106244591A
(zh)
*
|
2016-08-23 |
2016-12-21 |
苏州吉玛基因股份有限公司 |
修饰crRNA在CRISPR/Cpf1基因编辑系统中的应用
|
|
EA201892810A1
(ru)
|
2016-06-01 |
2019-06-28 |
Квс Заат Се |
Гибридные последовательности нуклеиновых кислот для геномной инженерии
|
|
US10767175B2
(en)
|
2016-06-08 |
2020-09-08 |
Agilent Technologies, Inc. |
High specificity genome editing using chemically modified guide RNAs
|
|
JP2019519242A
(ja)
|
2016-06-30 |
2019-07-11 |
ザイマージェン インコーポレイテッド |
細菌ヘモグロビンライブラリーを生成するための方法およびその使用
|
|
WO2018005793A1
(en)
|
2016-06-30 |
2018-01-04 |
Zymergen Inc. |
Methods for generating a glucose permease library and uses thereof
|
|
WO2018009822A1
(en)
|
2016-07-08 |
2018-01-11 |
Ohio State Innovation Foundation |
Modified nucleic acids, hybrid guide rnas, and uses thereof
|
|
KR20250103795A
(ko)
|
2016-08-03 |
2025-07-07 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
아데노신 핵염기 편집제 및 그의 용도
|
|
US11661590B2
(en)
|
2016-08-09 |
2023-05-30 |
President And Fellows Of Harvard College |
Programmable CAS9-recombinase fusion proteins and uses thereof
|
|
WO2018031950A1
(en)
|
2016-08-12 |
2018-02-15 |
Caribou Biosciences, Inc. |
Protein engineering methods
|
|
WO2018034554A1
(ko)
|
2016-08-19 |
2018-02-22 |
주식회사 툴젠 |
인위적으로 조작된 신생혈관형성 조절 시스템
|
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
US11306305B2
(en)
|
2016-09-23 |
2022-04-19 |
Board Of Trustees Of Southern Illinois University |
Tuning CRISPR/Cas9 activity with chemically modified nucleotide substitutions
|
|
US11242542B2
(en)
|
2016-10-07 |
2022-02-08 |
Integrated Dna Technologies, Inc. |
S. pyogenes Cas9 mutant genes and polypeptides encoded by same
|
|
CA3039409A1
(en)
|
2016-10-07 |
2018-04-12 |
Integrated Dna Technologies, Inc. |
S. pyogenes cas9 mutant genes and polypeptides encoded by same
|
|
SG11201903089RA
(en)
|
2016-10-14 |
2019-05-30 |
Harvard College |
Aav delivery of nucleobase editors
|
|
US20180282722A1
(en)
*
|
2016-11-21 |
2018-10-04 |
Massachusetts Institute Of Technology |
Chimeric DNA:RNA Guide for High Accuracy Cas9 Genome Editing
|
|
AU2017364084B2
(en)
*
|
2016-11-22 |
2024-07-04 |
Integrated Dna Technologies, Inc. |
CRISPR/Cpf1 systems and methods
|
|
US9816093B1
(en)
|
2016-12-06 |
2017-11-14 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
|
US11293022B2
(en)
|
2016-12-12 |
2022-04-05 |
Integrated Dna Technologies, Inc. |
Genome editing enhancement
|
|
WO2018119010A1
(en)
|
2016-12-19 |
2018-06-28 |
Editas Medicine, Inc. |
Assessing nuclease cleavage
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
US20190382751A1
(en)
*
|
2016-12-28 |
2019-12-19 |
Ionis Pharmaceuticals, Inc. |
Modified crispr rna and uses thereof
|
|
EP3565907B1
(en)
|
2017-01-06 |
2022-05-04 |
Editas Medicine, Inc. |
Methods of assessing nuclease cleavage
|
|
DK3574101T5
(da)
*
|
2017-01-30 |
2024-09-02 |
Kws Saat Se & Co Kgaa |
Reparationsskabelonbinding til endonukleaser til genommodifikation
|
|
EP3592381A1
(en)
|
2017-03-09 |
2020-01-15 |
President and Fellows of Harvard College |
Cancer vaccine
|
|
US11898179B2
(en)
|
2017-03-09 |
2024-02-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
|
WO2018165629A1
(en)
|
2017-03-10 |
2018-09-13 |
President And Fellows Of Harvard College |
Cytosine to guanine base editor
|
|
WO2018176009A1
(en)
|
2017-03-23 |
2018-09-27 |
President And Fellows Of Harvard College |
Nucleobase editors comprising nucleic acid programmable dna binding proteins
|
|
PT3526324T
(pt)
|
2017-03-28 |
2021-10-20 |
Locanabio Inc |
Proteína associada a crispr (cas)
|
|
US11499151B2
(en)
|
2017-04-28 |
2022-11-15 |
Editas Medicine, Inc. |
Methods and systems for analyzing guide RNA molecules
|
|
WO2018209320A1
(en)
|
2017-05-12 |
2018-11-15 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
|
|
US11603544B2
(en)
|
2017-06-05 |
2023-03-14 |
Fred Hutchinson Cancer Center |
Genomic safe harbors for genetic therapies in human stem cells and engineered nanoparticles to provide targeted genetic therapies
|
|
CN108977442B
(zh)
*
|
2017-06-05 |
2023-01-06 |
广州市锐博生物科技有限公司 |
用于dna编辑的系统及其应用
|
|
KR20200026878A
(ko)
|
2017-06-06 |
2020-03-11 |
지머젠 인코포레이티드 |
균류 균주를 개량하기 위한 htp 게놈 공학 플랫폼
|
|
KR20200026874A
(ko)
|
2017-06-06 |
2020-03-11 |
지머젠 인코포레이티드 |
대장균 개량을 위한 htp 게놈 공학 플랫폼
|
|
US20200190508A1
(en)
*
|
2017-06-07 |
2020-06-18 |
Arc Bio, Llc |
Creation and use of guide nucleic acids
|
|
JP7518620B2
(ja)
|
2017-06-09 |
2024-07-18 |
エディタス・メディシン，インコーポレイテッド |
操作されたｃａｓ９ヌクレアーゼ
|
|
MX2019015143A
(es)
|
2017-06-14 |
2020-07-27 |
Wisconsin Alumni Res Found |
Rna guias modificados, complejos crispr-ribonucleoproteina y metodos de uso.
|
|
WO2019014564A1
(en)
|
2017-07-14 |
2019-01-17 |
Editas Medicine, Inc. |
SYSTEMS AND METHODS OF TARGETED INTEGRATION AND GENOME EDITING AND DETECTION THEREOF WITH INTEGRATED PRIMING SITES
|
|
US11584955B2
(en)
*
|
2017-07-14 |
2023-02-21 |
Shanghai Tolo Biotechnology Company Limited |
Application of Cas protein, method for detecting target nucleic acid molecule and kit
|
|
CN107488710B
(zh)
|
2017-07-14 |
2020-09-22 |
上海吐露港生物科技有限公司 |
一种Cas蛋白的用途及靶标核酸分子的检测方法和试剂盒
|
|
CN111801345A
(zh)
|
2017-07-28 |
2020-10-20 |
哈佛大学的校长及成员们 |
使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
|
|
CN111373040B
(zh)
|
2017-08-09 |
2024-07-12 |
本森希尔股份有限公司 |
修饰基因组的组合物和方法
|
|
EP3676376B1
(en)
|
2017-08-30 |
2025-01-15 |
President and Fellows of Harvard College |
High efficiency base editors comprising gam
|
|
EP3676378A4
(en)
|
2017-08-31 |
2021-06-09 |
The New York Genome Center |
PROCEDURES AND COMPOSITIONS USING CRIMP-CPF1 AND PAIRED GUIDE-CRISPR-RNA FOR PROGRAMMABLE GENOMIC DELETIONS
|
|
US11795443B2
(en)
|
2017-10-16 |
2023-10-24 |
The Broad Institute, Inc. |
Uses of adenosine base editors
|
|
WO2019099943A1
(en)
|
2017-11-16 |
2019-05-23 |
Astrazeneca Ab |
Compositions and methods for improving the efficacy of cas9-based knock-in strategies
|
|
US20210002609A1
(en)
|
2017-12-05 |
2021-01-07 |
Caribou Biosciences, Inc. |
Modified lymphocytes
|
|
WO2019118949A1
(en)
|
2017-12-15 |
2019-06-20 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
WO2019118893A1
(en)
|
2017-12-15 |
2019-06-20 |
Dana-Farber Cancer Institute, Inc. |
Stabilized peptide-mediated targeted protein degradation
|
|
WO2019147743A1
(en)
*
|
2018-01-26 |
2019-08-01 |
Massachusetts Institute Of Technology |
Structure-guided chemical modification of guide rna and its applications
|
|
WO2019152941A1
(en)
|
2018-02-05 |
2019-08-08 |
Caribou Biosciences, Inc. |
Engineered gut microbes for reduction of reactivation of detoxified drugs
|
|
EP3755792A4
(en)
|
2018-02-23 |
2021-12-08 |
Pioneer Hi-Bred International, Inc. |
NEW CAS9 ORTHOLOGIST
|
|
WO2019173248A1
(en)
|
2018-03-07 |
2019-09-12 |
Caribou Biosciences, Inc. |
Engineered nucleic acid-targeting nucleic acids
|
|
GB2587970B
(en)
|
2018-04-19 |
2023-02-08 |
Univ California |
Compositions and methods for gene editing
|
|
EP3794130A4
(en)
|
2018-05-16 |
2022-07-27 |
Synthego Corporation |
METHODS AND SYSTEMS FOR DESIGNING AND USING GUIDE RNA
|
|
US12157760B2
(en)
|
2018-05-23 |
2024-12-03 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
US12227776B2
(en)
|
2018-06-13 |
2025-02-18 |
Caribou Biosciences, Inc. |
Engineered cascade components and cascade complexes
|
|
US10227576B1
(en)
|
2018-06-13 |
2019-03-12 |
Caribou Biosciences, Inc. |
Engineered cascade components and cascade complexes
|
|
CN112272704A
(zh)
*
|
2018-06-13 |
2021-01-26 |
卡里布生物科学公司 |
改造的cascade组分和cascade复合体
|
|
AU2019291918B2
(en)
|
2018-06-29 |
2025-06-12 |
Editas Medicine, Inc. |
Synthetic guide molecules, compositions and methods relating thereto
|
|
EP3820495A4
(en)
|
2018-07-09 |
2022-07-20 |
The Broad Institute Inc. |
RNA-PROGRAMMABLE EPIGENETIC RNA MODIFIERS AND THEIR USES
|
|
EP3847251A1
(en)
|
2018-09-07 |
2021-07-14 |
Astrazeneca AB |
Compositions and methods for improved nucleases
|
|
EP3833682B1
(en)
|
2018-10-01 |
2022-08-17 |
Caribou Biosciences, Inc. |
Suicide module compositions and methods
|
|
KR102126573B1
(ko)
|
2018-10-18 |
2020-06-26 |
대한민국 |
CRISPR-Cas9 시스템을 이용한 유색고약버섯의 리그닌 분해효소의 유전자 편집방법 및 이의 용도
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
SG11202104409YA
(en)
*
|
2018-10-31 |
2021-05-28 |
Zymergen Inc |
Multiplexed deterministic assembly of dna libraries
|
|
US11739320B2
(en)
|
2018-11-05 |
2023-08-29 |
Wisconsin Alumni Research Foundation |
Gene correction of Pompe disease and other autosomal recessive disorders via RNA-guided nucleases
|
|
CN113166744B
(zh)
|
2018-12-14 |
2025-02-07 |
先锋国际良种公司 |
用于基因组编辑的新颖crispr-cas系统
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
AU2020210884A1
(en)
|
2019-01-25 |
2021-08-12 |
Synthego Corporation |
Systems and methods for modulating CRISPR activity
|
|
WO2020176389A1
(en)
|
2019-02-25 |
2020-09-03 |
Caribou Biosciences, Inc. |
Plasmids for gene editing
|
|
CA3129871A1
(en)
|
2019-03-08 |
2020-09-17 |
Zymergen Inc. |
Iterative genome editing in microbes
|
|
US11053515B2
(en)
|
2019-03-08 |
2021-07-06 |
Zymergen Inc. |
Pooled genome editing in microbes
|
|
EP3942043A2
(en)
|
2019-03-19 |
2022-01-26 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
US10982187B2
(en)
|
2019-03-26 |
2021-04-20 |
Genus Plc |
Bos taurus variety ‘HO840003150607238’ and methods of use thereof
|
|
WO2020214842A1
(en)
|
2019-04-17 |
2020-10-22 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
US10975351B2
(en)
|
2019-06-17 |
2021-04-13 |
Abs Global, Inc. |
Bos taurus variety ‘JE840003146074527’ and methods of use therof
|
|
CN114729381A
(zh)
*
|
2019-09-05 |
2022-07-08 |
本森希尔股份有限公司 |
修饰基因组的组合物和方法
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
US20230002761A1
(en)
|
2019-11-19 |
2023-01-05 |
Benson Hill, Inc. |
Anti-bacterial crispr compositions and methods
|
|
EP4438729A3
(en)
|
2019-12-09 |
2025-03-26 |
Caribou Biosciences, Inc. |
Crispr abasic restricted nucleotides and crispr accuracy via analogs
|
|
WO2021158918A1
(en)
*
|
2020-02-05 |
2021-08-12 |
Danmarks Tekniske Universitet |
Compositions and methods for targeting, editing or modifying human genes
|
|
WO2021173734A1
(en)
*
|
2020-02-24 |
2021-09-02 |
The Broad Institute, Inc. |
Novel type iv and type i crispr-cas systems and methods of use thereof
|
|
WO2021204877A2
(en)
|
2020-04-08 |
2021-10-14 |
Astrazeneca Ab |
Compositions and methods for improved site-specific modification
|
|
BR112022022603A2
(pt)
|
2020-05-08 |
2023-01-17 |
Broad Inst Inc |
Métodos e composições para edição simultânea de ambas as fitas de sequência alvo de nucleotídeos de fita dupla
|
|
WO2021231606A2
(en)
*
|
2020-05-12 |
2021-11-18 |
University Of Massachusetts |
Modified guide rnas for crispr genome editing
|
|
WO2022086846A2
(en)
*
|
2020-10-19 |
2022-04-28 |
Caribou Biosciences, Inc. |
Dna-containing polynucleotides and guides for crispr type v systems, and methods of making and using the same
|
|
CN112301162B
(zh)
*
|
2020-10-22 |
2023-09-22 |
清华-伯克利深圳学院筹备办公室 |
同时检测dna病毒和rna病毒的病毒核酸检测方法
|
|
EP4298212A4
(en)
*
|
2021-02-25 |
2026-04-15 |
Celyntra Therapeutics Sa |
Compositions and methods for targeting, editing, or modifying genes
|
|
JP2024513087A
(ja)
|
2021-04-07 |
2024-03-21 |
アストラゼネカ・アクチエボラーグ |
部位特異的改変のための組成物及び方法
|
|
GB2628238A
(en)
*
|
2021-09-22 |
2024-09-18 |
Verve Therapeutics Inc |
Gene editing of PCSK9 or ANGPTL3 and compositions and methods of using same for treatment of disease
|
|
EP4408996A2
(en)
|
2021-09-30 |
2024-08-07 |
Astrazeneca AB |
Use of inhibitors to increase efficiency of crispr/cas insertions
|
|
US20250019739A1
(en)
|
2021-10-26 |
2025-01-16 |
Caribou Biosciences, Inc. |
Exonuclease-coupled real-time endonuclease activity assay
|
|
KR20240099447A
(ko)
*
|
2021-12-07 |
2024-06-28 |
카리부 바이오사이언시스 인코포레이티드 |
Crispr 엔도뉴클레아제 절단 생성물을 포획하는 방법
|
|
WO2023185697A2
(en)
*
|
2022-03-29 |
2023-10-05 |
Accuredit Therapeutics (Suzhou) Co., Ltd. |
Compositions and methods for treatment of transthyretin amyloidosis
|
|
EP4508211A2
(en)
*
|
2022-04-13 |
2025-02-19 |
Caribou Biosciences, Inc. |
Therapeutic applications of crispr type v systems
|
|
WO2023224327A1
(ko)
*
|
2022-05-20 |
2023-11-23 |
한국생명공학연구원 |
오토라이신을 활용한 미세조류의 유전자 교정 효율을 증대시키기 위한 시스템 및 방법
|
|
US20260035424A1
(en)
|
2022-05-26 |
2026-02-05 |
Caribou Biosciences, Inc. |
Cytokine-receptor fusions for immune cell stimulation
|
|
EP4511057A1
(en)
|
2022-06-06 |
2025-02-26 |
Caribou Biosciences, Inc. |
Treatment of autoimmune diseases with engineered immune cells
|
|
EP4578945A4
(en)
|
2022-08-26 |
2025-12-17 |
Guangzhou Reforgene Medicine Co Ltd |
CRISPR-CAS13 SYSTEM AND ITS USE
|
|
KR20250075567A
(ko)
|
2022-09-30 |
2025-05-28 |
카리부 바이오사이언시스 인코포레이티드 |
항-ror1 키메라 항원 수용체 (car), car-nk 세포 및 관련 방법
|
|
EP4584283A1
(en)
|
2022-11-14 |
2025-07-16 |
Caribou Biosciences, Inc. |
Anti-cll-1 chimeric antigen receptors, engineered cells and related methods
|
|
EP4414452A1
(en)
*
|
2023-02-13 |
2024-08-14 |
Universidad de Granada |
Dual-guide rna composition for executing a single-guide rna crispr-associated system
|
|
EP4689155A1
(en)
|
2023-03-29 |
2026-02-11 |
Astrazeneca AB |
Use of inhibitors to increase efficiency of crispr/cas insertions
|
|
US20260014254A1
(en)
|
2023-05-01 |
2026-01-15 |
Caribou Bioscience, Inc. |
Treatment of autoimmune diseases with bcma-targeting engineered immune cells
|
|
IL324634A
(en)
|
2023-05-15 |
2026-01-01 |
Nchroma Bio Inc |
Compositions and methods for epigenetic regulation of hbv gene expression
|
|
WO2025006880A1
(en)
|
2023-06-29 |
2025-01-02 |
Caribou Biosciences, Inc. |
Diagnostic and therapeutic methods for use with ror1 antagonists
|
|
WO2025024676A1
(en)
|
2023-07-26 |
2025-01-30 |
Caribou Biosciences, Inc. |
In vitro validation methods for cd19-targeting cell therapies
|
|
WO2025026439A1
(zh)
|
2023-08-02 |
2025-02-06 |
广州瑞风生物科技有限公司 |
基因编辑系统及其应用
|
|
CN119614679A
(zh)
*
|
2023-09-14 |
2025-03-14 |
厦门大学 |
一款通用型核酸检测平台
|
|
WO2025064930A1
(en)
*
|
2023-09-20 |
2025-03-27 |
Emory University |
Nucleic acid hairpin based triggered hydrogels and uses thereof
|
|
WO2025117745A1
(en)
|
2023-12-01 |
2025-06-05 |
Caribou Biosciences, Inc. |
Methods and compositions for improving precision of endonuclease-mediated genome editing
|
|
WO2025193609A1
(en)
|
2024-03-11 |
2025-09-18 |
Caribou Biosciences, Inc. |
Methods and compositions for cost-effective assessment of nucleic acid transcripts and isoforms in cells
|
|
WO2025193386A1
(en)
|
2024-03-13 |
2025-09-18 |
Caribou Biosciences, Inc. |
Treatment regimens for autoimmune disease with cd19-targeting engineered immune cells
|
|
WO2026024468A1
(en)
|
2024-07-26 |
2026-01-29 |
Caribou Biosciences, Inc. |
Modular linked chimeric antigen receptors
|
|
WO2026050087A1
(en)
|
2024-08-27 |
2026-03-05 |
Caribou Biosciences, Inc. |
Real-time crispr endonuclease activity assay
|
|
US20260085302A1
(en)
|
2024-09-20 |
2026-03-26 |
Confluence Genetics, Llc |
Compositions and methods for controlling plant pests
|
|
WO2026062583A2
(en)
|
2024-09-20 |
2026-03-26 |
Confluence Genetics, Llc |
Compositions and methods for modifying genomes
|
|
WO2026083309A1
(en)
|
2024-10-17 |
2026-04-23 |
Astrazeneca Ab |
Use of inhibitors or modulators of artemis in gene editing
|