PT3250691T - Polinucleótidos crispr híbridos de dna/rna e métodos de utilização - Google Patents

Polinucleótidos crispr híbridos de dna/rna e métodos de utilização

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Publication number
PT3250691T
PT3250691T PT167049782T PT16704978T PT3250691T PT 3250691 T PT3250691 T PT 3250691T PT 167049782 T PT167049782 T PT 167049782T PT 16704978 T PT16704978 T PT 16704978T PT 3250691 T PT3250691 T PT 3250691T
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PT
Portugal
Prior art keywords
methods
hybrid dna
rna polynucleotides
crispr
crispr hybrid
Prior art date
Application number
PT167049782T
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English (en)
Original Assignee
Caribou Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caribou Biosciences Inc filed Critical Caribou Biosciences Inc
Publication of PT3250691T publication Critical patent/PT3250691T/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N9/14—Hydrolases (3)
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    • C12N9/22—Ribonucleases RNAses, DNAses
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin
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    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity
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PT167049782T 2015-01-28 2016-01-27 Polinucleótidos crispr híbridos de dna/rna e métodos de utilização PT3250691T (pt)

Applications Claiming Priority (2)

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US201562108931P 2015-01-28 2015-01-28
US201562251548P 2015-11-05 2015-11-05

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PT3250691T true PT3250691T (pt) 2023-09-25

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US (10) US9650617B2 (pt)
EP (2) EP3250691B9 (pt)
JP (2) JP6835726B2 (pt)
KR (4) KR102319192B1 (pt)
CN (2) CN111518811A (pt)
AU (3) AU2016211517B2 (pt)
BR (1) BR112017016080B1 (pt)
CA (2) CA2975166C (pt)
DK (1) DK3250691T3 (pt)
ES (1) ES2955957T3 (pt)
FI (1) FI3250691T3 (pt)
GB (1) GB2550745A (pt)
HK (1) HK1245839A1 (pt)
HR (1) HRP20231022T1 (pt)
HU (1) HUE063813T2 (pt)
IL (4) IL288263B (pt)
LT (1) LT3250691T (pt)
MX (1) MX2017009506A (pt)
NZ (1) NZ733702A (pt)
PL (1) PL3250691T3 (pt)
PT (1) PT3250691T (pt)
RS (1) RS64527B1 (pt)
RU (1) RU2713328C2 (pt)
SG (3) SG11201705788TA (pt)
SI (1) SI3250691T1 (pt)
WO (1) WO2016123230A1 (pt)
ZA (2) ZA201705174B (pt)

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