|
GB1555654A
(en)
|
1977-06-25 |
1979-11-14 |
Exxon Research Engineering Co |
Agricultural burner apparatus
|
|
US4065562A
(en)
|
1975-12-29 |
1977-12-27 |
Nippon Shinyaku Co., Ltd. |
Method and composition for reducing blood glucose levels
|
|
NO154918C
(no)
|
1977-08-27 |
1987-01-14 |
Bayer Ag |
Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
|
|
GB2020278B
(en)
|
1978-05-03 |
1983-02-23 |
Nippon Shinyaku Co Ltd |
Moranoline dervitives
|
|
JPS568318A
(en)
|
1979-06-28 |
1981-01-28 |
Janssen Pharmaceutica Nv |
Non oral long acting composition of haloperidol and bromperidol derivative
|
|
GB8311286D0
(en)
|
1983-04-26 |
1983-06-02 |
Searle & Co |
Carboxyalkyl peptide derivatives
|
|
EP0144290A3
(de)
|
1983-12-01 |
1987-05-27 |
Ciba-Geigy Ag |
Substituierte Aethylendiaminderivate
|
|
US5041441A
(en)
|
1988-04-04 |
1991-08-20 |
The Regents Of The University Of Michigan |
Method of chemotherapy using 1-phenyl-2-decanoylamino-3-morpholino-1-propanol
|
|
JPH0416856A
(ja)
|
1990-05-10 |
1992-01-21 |
Canon Inc |
正帯電性非磁性トナー
|
|
JPH04140984A
(ja)
|
1990-10-02 |
1992-05-14 |
Canon Inc |
スチルビデオカメラ
|
|
RU2005102C1
(ru)
*
|
1991-06-21 |
1993-12-30 |
Институт геологии Карельского научного центра РАН |
Способ получени декоративного стекла
|
|
US5302609A
(en)
|
1992-12-16 |
1994-04-12 |
The Regents Of The University Of Michigan |
Treatment of diabetic nephropathy
|
|
US5399567A
(en)
|
1993-05-13 |
1995-03-21 |
Monsanto Company |
Method of treating cholera
|
|
ATE197672T1
(de)
|
1993-08-13 |
2000-12-15 |
Seikagaku Kogyo Co Ltd |
Arzneimittel gegen nervöse erkrankungen
|
|
EP0742789B1
(en)
|
1994-02-02 |
2000-08-30 |
The Liposome Company, Inc. |
Pharmaceutically active compounds and liposomes, and methods of use therof
|
|
AU698833B2
(en)
|
1994-06-10 |
1998-11-12 |
Seikagaku Corporation |
2-acylaminopropanol compound and medical composition
|
|
US20030073680A1
(en)
|
1995-09-20 |
2003-04-17 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
WO2001004108A1
(en)
|
1999-07-09 |
2001-01-18 |
Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US6255336B1
(en)
|
1995-09-20 |
2001-07-03 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US5916911A
(en)
|
1995-09-20 |
1999-06-29 |
The Regents Of The University Of Michigan |
Amino ceramide--like compounds and therapeutic methods of use
|
|
NO965193L
(no)
|
1995-12-08 |
1997-06-09 |
Seikagaku Kogyo Kk Seikagaku C |
Aminalkoholderivat og fremgangsmåte for fremstilling derav
|
|
JP3993908B2
(ja)
|
1995-12-08 |
2007-10-17 |
生化学工業株式会社 |
アミノアルコール誘導体及び該誘導体の製造方法
|
|
JP4140984B2
(ja)
|
1995-12-20 |
2008-08-27 |
生化学工業株式会社 |
分化誘導作用を有する薬剤
|
|
US5972928A
(en)
|
1997-05-21 |
1999-10-26 |
Johns Hopkins University |
Methods for treatment of conditions associated with lactosylceramide
|
|
JP4036500B2
(ja)
|
1997-05-23 |
2008-01-23 |
生化学工業株式会社 |
アミノアルコール誘導体及びそれを含有する医薬
|
|
JP4176170B2
(ja)
|
1997-06-06 |
2008-11-05 |
生化学工業株式会社 |
アミノアルコール誘導体を含む医薬及び異常増殖性疾患治療薬
|
|
US6465488B1
(en)
|
1997-12-11 |
2002-10-15 |
Chancellor, Masters & Scholars Of The University Of Oxford |
Inhibition of glycolipid biosynthesis
|
|
AU756008B2
(en)
|
1998-07-27 |
2003-01-02 |
Johns Hopkins University, The |
Methods for treating conditions modulated by lactosylceramide
|
|
US6610703B1
(en)
|
1998-12-10 |
2003-08-26 |
G.D. Searle & Co. |
Method for treatment of glycolipid storage diseases
|
|
GB0100889D0
(en)
|
2001-01-12 |
2001-02-21 |
Oxford Glycosciences Uk Ltd |
Compounds
|
|
MXPA02000296A
(es)
*
|
1999-07-09 |
2004-05-21 |
Univ Michigan |
Compuestos parecidos a aminoceramida y metodos de uso.
|
|
EP1384719A1
(en)
|
1999-07-09 |
2004-01-28 |
The Regents of The University of Michigan |
Inhibitors of the glucosyl ceramide synthase enzyme useful for the treatment of cancers, sphingolipidosis and microbial infections
|
|
JP5009459B2
(ja)
*
|
1999-12-06 |
2012-08-22 |
生化学工業株式会社 |
アミノアルコール誘導体及びそれを含有する医薬
|
|
US6407064B2
(en)
|
1999-12-06 |
2002-06-18 |
Seikagaku Corporation |
Aminoalcohol derivative and medicament comprising the same
|
|
US6235737B1
(en)
|
2000-01-25 |
2001-05-22 |
Peter Styczynski |
Reduction of hair growth
|
|
PL357674A1
(pl)
|
2000-04-19 |
2004-07-26 |
Thomas Julius Borody |
Kompozycje i sposoby leczenia zaburzeń związanychz hiperlipidemią
|
|
AU2002241724A1
(en)
|
2000-12-20 |
2002-07-01 |
Bristol-Myers Squibb Company |
Diamines as modulators of chemokine receptor activity
|
|
CN100457719C
(zh)
|
2000-12-29 |
2009-02-04 |
惠氏公司 |
区域选择性制备取代的苯并[g]喹啉-3-腈和苯并[g]喹唑啉的方法
|
|
US7148251B2
(en)
|
2001-01-10 |
2006-12-12 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US20020198240A1
(en)
|
2001-01-10 |
2002-12-26 |
Shayman James A. |
Amino ceramide - like compounds and therapeutic methods of use
|
|
WO2002062777A2
(en)
|
2001-01-10 |
2002-08-15 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US20040260099A1
(en)
|
2001-01-10 |
2004-12-23 |
The Regents Of The University Of Michigan |
Amino ceramide-like compounds and therapeutic methods of use
|
|
ATE554082T1
(de)
|
2001-07-16 |
2012-05-15 |
Genzyme Corp |
N-acetylsphingosin glukosyltransferase inhibitor
|
|
AU2002348261A1
(en)
*
|
2001-11-26 |
2003-06-10 |
Genzyme Corporation |
Diastereoselective synthesis of udp-glucose : n-acylsphingosine glucosyltransferase inhibitors
|
|
GB0229931D0
(en)
|
2002-12-21 |
2003-01-29 |
Astrazeneca Ab |
Therapeutic agents
|
|
JPWO2003057874A1
(ja)
|
2001-12-28 |
2005-05-19 |
住友製薬株式会社 |
腎疾患の疾患マーカー及びその利用
|
|
CN101001857B
(zh)
*
|
2002-01-22 |
2011-06-22 |
沃尼尔·朗伯有限责任公司 |
2-(吡啶-2-基氨基)-吡啶并[2,3-d]嘧啶-7-酮
|
|
EP1336411A1
(en)
|
2002-02-14 |
2003-08-20 |
Academisch Medisch Centrum bij de Universiteit van Amsterdam |
Compositions and methods for improving enzyme replacement therapy of lysosomal storage diseases
|
|
JP2003238410A
(ja)
|
2002-02-21 |
2003-08-27 |
Seibutsu Yuki Kagaku Kenkyusho:Kk |
インスリン抵抗性解除剤
|
|
US6916802B2
(en)
|
2002-04-29 |
2005-07-12 |
Genzyme Corporation |
Amino ceramide-like compounds and therapeutic methods of use
|
|
US20060217560A1
(en)
|
2002-04-29 |
2006-09-28 |
Shayman James A |
Amino ceramide-like compounds and therapeutic methods of use
|
|
GEP20084499B
(en)
|
2002-07-17 |
2008-10-10 |
Biogen Idec Inc |
USE OF INTERFERON-ß FOR TREATMENT OF RENAL FAILURE
|
|
JP4575156B2
(ja)
|
2002-07-17 |
2010-11-04 |
アクテリオン ファーマシューティカルズ リミテッド |
グルコシルセラミドシンターゼの阻害剤としてのピペリジントリオール誘導体
|
|
AU2003225670A1
(en)
|
2003-02-28 |
2004-09-28 |
Intermune, Inc. |
Interferon drug therapy for the treatment of viral diseases and liver fibrosis
|
|
GB0313678D0
(en)
|
2003-06-13 |
2003-07-16 |
Oxford Glycosciences Uk Ltd |
Novel compounds
|
|
EP1528056A1
(en)
|
2003-10-29 |
2005-05-04 |
Academisch Ziekenhuis bij de Universiteit van Amsterdam |
Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors
|
|
AU2004283631A1
(en)
|
2003-10-29 |
2005-05-06 |
Genzyme Corporation |
Use of a deoxynojirimycin derivative or a pharmaceutically salt thereof
|
|
JP2007516294A
(ja)
|
2003-12-23 |
2007-06-21 |
エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント |
炎症性の疾患または症状の予防および治療のための方法および組成物
|
|
GB0400812D0
(en)
|
2004-01-14 |
2004-02-18 |
Celltech R&D Ltd |
Novel compounds
|
|
JP5154218B2
(ja)
|
2004-03-16 |
2013-02-27 |
ネーデルランドセ オルガニサティエ フォール トエゲパスト−ナトールヴェテンシャッペリク オンデルゾエク ティエヌオー |
２型糖尿病、インスリン抵抗性及びメタボリック症候群の治療及び予防においてスフィンゴ脂質を使用する方法
|
|
EP1576894A1
(en)
|
2004-03-16 |
2005-09-21 |
Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO |
The use of sphingolipids in the treatment and prevention of type 2 diabetes mellitus, insulin resistance and Metabolic Syndrome
|
|
ES2375626T3
(es)
|
2004-05-07 |
2012-03-02 |
Merck Patent Gmbh |
Gm3 sintetasa como diana terapéutica en las complicaciones microvasculares de la diabetes.
|
|
US20090111812A1
(en)
|
2004-06-14 |
2009-04-30 |
Musc Foundation For Research Development |
Methods for treating inflammatory disorders
|
|
CN101123879A
(zh)
|
2004-08-20 |
2008-02-13 |
约翰·霍普金斯大学 |
血管新生治疗方法
|
|
BRPI0517701A8
(pt)
|
2004-11-10 |
2018-01-23 |
Genzyme Corp |
métodos de tratamento de diabetes mellitus
|
|
WO2006081273A1
(en)
|
2005-01-26 |
2006-08-03 |
Allergan, Inc. |
3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroayryl-3-hydroxy-2-amino-propionic acid amides and related compounds having analgesic and/or immunostimulant activity
|
|
WO2007022518A2
(en)
|
2005-08-19 |
2007-02-22 |
Amylin Pharmaceuticals, Inc. |
New uses of glucoregulatory proteins
|
|
ES2546181T3
(es)
|
2006-05-09 |
2015-09-21 |
Genzyme Corporation |
Métodos de tratar la enfermedad del hígado graso mediante inhibición de la síntesis de glucoesfingolípidos
|
|
WO2008011478A2
(en)
|
2006-07-19 |
2008-01-24 |
Allergan, Inc. |
Methods for treating chronic pain using 3-aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds
|
|
WO2008011487A2
(en)
|
2006-07-19 |
2008-01-24 |
Allergan, Inc. |
L-benzyl-l-hydr0xy-2, 3-diamin0-propyl amines and 3-benzyl-3-hydroxy-2-amino-propionicacid amides for chronic pain
|
|
GB0614947D0
(en)
|
2006-07-27 |
2006-09-06 |
Isis Innovation |
Epitope reduction therapy
|
|
TWI389895B
(zh)
|
2006-08-21 |
2013-03-21 |
Infinity Discovery Inc |
抑制ｂｃｌ蛋白質與結合夥伴間之交互作用的化合物及方法
|
|
EA200901082A1
(ru)
*
|
2007-02-09 |
2010-02-26 |
Айрм Ллк |
Соединения и композиции в качестве ингибиторов протеазы, активирующей каналы
|
|
EP2594563B1
(en)
*
|
2007-05-31 |
2018-07-18 |
Genzyme Corporation |
2-acylaminopropanol-type glucosylceramide synthase inhibitors
|
|
CA2701649C
(en)
*
|
2007-10-05 |
2016-05-24 |
Genzyme Corporation |
Method of treating polycystic kidney diseases with ceramide derivatives
|
|
WO2009117150A2
(en)
|
2008-03-20 |
2009-09-24 |
Genzyme Corporation |
Method of treating lupus with ceramide derivatives
|
|
CA2731685A1
(en)
|
2008-07-28 |
2010-02-04 |
Genzyme Corporation |
Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease
|
|
CN102271678B
(zh)
|
2008-10-03 |
2017-06-30 |
简詹姆公司 |
2‑酰胺基丙醇型葡糖神经酰胺合成酶抑制剂
|