PT99919A - Processo para a preparacao de derivados de xantina - Google Patents

Processo para a preparacao de derivados de xantina

Info

Publication number
PT99919A
PT99919A PT99919A PT9991991A PT99919A PT 99919 A PT99919 A PT 99919A PT 99919 A PT99919 A PT 99919A PT 9991991 A PT9991991 A PT 9991991A PT 99919 A PT99919 A PT 99919A
Authority
PT
Portugal
Prior art keywords
substituted
group
unsubstituted
formula
pct
Prior art date
Application number
PT99919A
Other languages
English (en)
Other versions
PT99919B (pt
Inventor
Derek Richard Buckle
David Glynn Smith
Ashley Edward Fenwick
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909027752A external-priority patent/GB9027752D0/en
Priority claimed from GB909027899A external-priority patent/GB9027899D0/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of PT99919A publication Critical patent/PT99919A/pt
Publication of PT99919B publication Critical patent/PT99919B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Led Devices (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT99919A 1990-12-21 1991-12-20 Processo para a preparacao de derivados de xantina PT99919B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909027752A GB9027752D0 (en) 1990-12-21 1990-12-21 Novel compounds
GB909027899A GB9027899D0 (en) 1990-12-21 1990-12-21 Novel compounds

Publications (2)

Publication Number Publication Date
PT99919A true PT99919A (pt) 1992-12-31
PT99919B PT99919B (pt) 1999-06-30

Family

ID=26298155

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99919A PT99919B (pt) 1990-12-21 1991-12-20 Processo para a preparacao de derivados de xantina

Country Status (14)

Country Link
US (1) US5409934A (pt)
EP (1) EP0563168B1 (pt)
JP (1) JPH06504534A (pt)
KR (1) KR930703319A (pt)
AT (1) ATE194345T1 (pt)
AU (1) AU649091B2 (pt)
CA (1) CA2098846A1 (pt)
DE (1) DE69132291T2 (pt)
ES (1) ES2148170T3 (pt)
IE (1) IE914502A1 (pt)
MX (1) MX9102766A (pt)
NZ (1) NZ241158A (pt)
PT (1) PT99919B (pt)
WO (1) WO1992011260A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9210839D0 (en) * 1992-05-21 1992-07-08 Smithkline Beecham Plc Novel compounds
US5646156A (en) * 1994-04-25 1997-07-08 Merck & Co., Inc. Inhibition of eosinophil activation through A3 adenosine receptor antagonism
CA2218548A1 (en) * 1995-05-19 1996-11-21 Chiroscience Limited Xanthines and their therapeutic use
US5981549A (en) * 1997-02-14 1999-11-09 Synapse Pharmaceutical International Method for controlling or alleviating the symptoms of respiratory disease and allergies
AR015966A1 (es) * 1997-10-17 2001-05-30 Smithkline Beecham Corp Uso de un compuesto inhibidor de pde4 para la preparacion de un medicamento util para el tratamiento de prurito
US6133273A (en) * 1998-05-08 2000-10-17 American Home Products Corporation Pyrazolopyrimidine-2,4-dione sulfonamides
US6221874B1 (en) * 1998-05-08 2001-04-24 American Home Products Corporation Method of treating bone loss by stimulation of calcitonin
DK1208100T3 (da) * 1999-08-31 2003-06-30 Univ Vanderbilt Selektive antagonister af A2B adenosinreceptorer
US6821978B2 (en) * 2000-09-19 2004-11-23 Schering Corporation Xanthine phosphodiesterase V inhibitors
JP3998118B2 (ja) * 2000-10-10 2007-10-24 本田技研工業株式会社 電動車両
JP4450365B2 (ja) * 2001-08-28 2010-04-14 シェーリング コーポレイション 多環式グアニンホスホジエステラーゼｖ阻害剤
CA2465893A1 (en) * 2001-11-09 2003-05-22 Schering Corporation Polycyclic guanine derivative phosphodiesterase v inhibitors
EP1719772A1 (en) 2002-05-31 2006-11-08 Schering Corporation Process for preparing xanthine phosphodiesterase v inhibitors and precursors thereof
US6924140B2 (en) * 2002-06-14 2005-08-02 Lewis J. Daly Closed loop work station bioremediation using mini-reactor cartridges
JP4491344B2 (ja) 2002-06-17 2010-06-30 グラクソ グループ リミテッド 肝ｘ受容体アゴニストとしてのプリン誘導体
US7312223B2 (en) * 2003-07-31 2007-12-25 Schering Corporation Metabolite of xanthine Phosphodiesterase 5 inhibitor and derivatives thereof useful for treatment of erectile dysfunction
JP2007512345A (ja) * 2003-11-21 2007-05-17 シェーリング　コーポレイション ホスホジエステラーゼｖ阻害剤処方物
US20070004745A1 (en) * 2005-03-25 2007-01-04 Schering-Plough Corporation Methods of treating benign prostatic hyperplasia or lower urinary tract symptoms by using PDE 5 inhibitors
CA2651519A1 (en) 2006-06-06 2007-12-13 Intra-Cellular Therapies, Inc. Organic compounds
KR20100094551A (ko) 2007-12-06 2010-08-26 인트라-셀룰라 써래피스, 인코퍼레이티드. 유기 화합물
AU2009322905A1 (en) 2008-12-06 2010-06-10 Intra-Cellular Therapies, Inc. Organic compounds
US8927556B2 (en) 2008-12-06 2015-01-06 Intra-Cellular Therapies, Inc. 1H-pyrrolo[3,4-D]pyrimidin-2(6H)-one compounds
EP2367430B1 (en) 2008-12-06 2014-08-13 Intra-Cellular Therapies, Inc. Organic compounds
JP5894148B2 (ja) 2010-05-31 2016-03-23 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 有機化合物
EP2575817A4 (en) 2010-05-31 2014-01-08 Intra Cellular Therapies Inc ORGANIC CONNECTIONS
US9546175B2 (en) 2014-08-07 2017-01-17 Intra-Cellular Therapies, Inc. Organic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3900474A (en) * 1973-05-14 1975-08-19 Kendall & Co Trifluoroalkyl, fluorobenzyl, pentafluorobenzyl, fluorobenzenesulfonyl, and pentafluorobenzenesulfonyl theophyllines
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
DE3916469A1 (de) * 1989-05-20 1990-11-22 Basf Ag Sulfonamide
GB9020959D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Novel compounds
GB9020921D0 (en) * 1990-09-26 1990-11-07 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
WO1992011260A1 (en) 1992-07-09
EP0563168B1 (en) 2000-07-05
NZ241158A (en) 1994-12-22
AU649091B2 (en) 1994-05-12
ATE194345T1 (de) 2000-07-15
ES2148170T3 (es) 2000-10-16
JPH06504534A (ja) 1994-05-26
CA2098846A1 (en) 1992-06-22
PT99919B (pt) 1999-06-30
US5409934A (en) 1995-04-25
EP0563168A1 (en) 1993-10-06
DE69132291T2 (de) 2000-12-14
DE69132291D1 (en) 2000-08-10
KR930703319A (ko) 1993-11-29
MX9102766A (es) 1992-09-01
AU9122791A (en) 1992-07-22
IE914502A1 (en) 1992-07-01

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920814

FG3A Patent granted, date of granting

Effective date: 19990304

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20000930