JP2017538712A5 - - Google Patents

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JP2017538712A5
JP2017538712A5 JP2017531307A JP2017531307A JP2017538712A5 JP 2017538712 A5 JP2017538712 A5 JP 2017538712A5 JP 2017531307 A JP2017531307 A JP 2017531307A JP 2017531307 A JP2017531307 A JP 2017531307A JP 2017538712 A5 JP2017538712 A5 JP 2017538712A5
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compound
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tautomer
item
salt
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JP2017531307A
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JP2017538712A (ja
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Priority claimed from PCT/US2015/065349 external-priority patent/WO2016094846A1/en
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JP2017531307A 2014-12-11 2015-12-11 細胞壊死の抑制剤及びそれに関連する方法 Pending JP2017538712A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CN201410767595.3 2014-12-11
CN201410767595 2014-12-11
CN201410764426.4 2014-12-11
CN201410764426 2014-12-11
US201562105462P 2015-01-20 2015-01-20
US201562105475P 2015-01-20 2015-01-20
US62/105,475 2015-01-20
US62/105,462 2015-01-20
PCT/US2015/065349 WO2016094846A1 (en) 2014-12-11 2015-12-11 Inhibitors of cellular necrosis and related methods

Publications (2)

Publication Number Publication Date
JP2017538712A JP2017538712A (ja) 2017-12-28
JP2017538712A5 true JP2017538712A5 (cg-RX-API-DMAC7.html) 2019-01-24

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JP2017531307A Pending JP2017538712A (ja) 2014-12-11 2015-12-11 細胞壊死の抑制剤及びそれに関連する方法

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US (3) US9944628B2 (cg-RX-API-DMAC7.html)
EP (1) EP3229807A4 (cg-RX-API-DMAC7.html)
JP (1) JP2017538712A (cg-RX-API-DMAC7.html)
KR (1) KR20170123607A (cg-RX-API-DMAC7.html)
CN (1) CN107530350A (cg-RX-API-DMAC7.html)
AR (1) AR102981A1 (cg-RX-API-DMAC7.html)
AU (1) AU2015360291A1 (cg-RX-API-DMAC7.html)
CA (1) CA2970525A1 (cg-RX-API-DMAC7.html)
EA (1) EA201791289A1 (cg-RX-API-DMAC7.html)
IL (1) IL252827A0 (cg-RX-API-DMAC7.html)
MX (1) MX2017007607A (cg-RX-API-DMAC7.html)
SG (1) SG11201704764PA (cg-RX-API-DMAC7.html)
TW (1) TW201632516A (cg-RX-API-DMAC7.html)
WO (1) WO2016094846A1 (cg-RX-API-DMAC7.html)

Families Citing this family (13)

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JP2016514693A (ja) 2013-03-15 2016-05-23 プレジデント アンド フェローズ オブ ハーバード カレッジ ハイブリッド型ネクロトーシス阻害剤
AU2015360291A1 (en) 2014-12-11 2017-07-13 President And Fellows Of Harvard College Inhibitors of cellular necrosis and related methods
CN106619619A (zh) * 2017-01-06 2017-05-10 浙江大学 化合物hubin‑1在制备肝脏炎症性疾病预防和/或治疗药物中的用途
CA3052767A1 (en) 2017-02-27 2018-08-30 Glaxosmithkline Intellectual Property Development Limited Heterocyclic amides as kinase inhibitors
EP3625234B1 (en) * 2017-05-17 2023-09-20 Denali Therapeutics Inc. Hexahydropyrazolo [1,2-a] diazepinones and related heterocycles as inhibitors of rip-1 kinase
CN108191835A (zh) * 2018-01-09 2018-06-22 中国药科大学 一类新型的含吡咯环和吲哚啉结构rip1激酶抑制剂及其用途
CN110759895B (zh) * 2018-07-25 2020-10-27 浙江大学 新型rip1/rip3双靶点抑制剂及其在一药多靶疾病治疗中的用途
WO2020044206A1 (en) 2018-08-29 2020-03-05 Glaxosmithkline Intellectual Property Development Limited Heterocyclic amides as kinase inhibitors for use in the treatment cancer
CN111978311B (zh) * 2019-05-21 2024-05-31 中国科学院上海有机化学研究所 一类细胞程序性坏死抑制剂及其制备方法和用途
US20210147842A1 (en) * 2019-11-13 2021-05-20 President And Fellows Of Harvard College Methods and compositions for inhibiting necroptosis in neurovascular and/or neurodegenerative diseases or disorders
CN112263576A (zh) * 2020-09-30 2021-01-26 浙江大学 化合物zju-37在制备肝脏疾病预防和/或治疗药物中的应用

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