JP2017537905A - アルツハイマー病の治療法 - Google Patents

アルツハイマー病の治療法 Download PDF

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Publication number
JP2017537905A
JP2017537905A JP2017527872A JP2017527872A JP2017537905A JP 2017537905 A JP2017537905 A JP 2017537905A JP 2017527872 A JP2017527872 A JP 2017527872A JP 2017527872 A JP2017527872 A JP 2017527872A JP 2017537905 A JP2017537905 A JP 2017537905A
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patient
dose
body weight
antibody
amount
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JP2017537905A5 (enExample
Inventor
ジェイムズ エル． フェレーロ，
ジェイムズ エル． フェレーロ，
レスリー ルジーン ウイリアムズ，
レスリー ルジーン ウイリアムズ，
ジェフリー ジョセフ セヴィニー，
ジェフリー ジョセフ セヴィニー，
Original Assignee
バイオジェン インターナショナル ニューロサイエンス ゲーエムベーハー
バイオジェン インターナショナル ニューロサイエンス ゲーエムベーハー
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Publication of JP2017537905A publication Critical patent/JP2017537905A/ja
Publication of JP2017537905A5 publication Critical patent/JP2017537905A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2017527872A 2014-12-02 2015-12-02 アルツハイマー病の治療法 Withdrawn JP2017537905A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201462086674P 2014-12-02 2014-12-02
US62/086,674 2014-12-02
US201562111874P 2015-02-04 2015-02-04
US62/111,874 2015-02-04
US201562149133P 2015-04-17 2015-04-17
US62/149,133 2015-04-17
US201562195119P 2015-07-21 2015-07-21
US62/195,119 2015-07-21
PCT/IB2015/002465 WO2016087944A2 (en) 2014-12-02 2015-12-02 Method for treating alzheimer's disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020004429A Division JP2020055880A (ja) 2014-12-02 2020-01-15 アルツハイマー病の治療法

Publications (2)

Publication Number Publication Date
JP2017537905A true JP2017537905A (ja) 2017-12-21
JP2017537905A5 JP2017537905A5 (enExample) 2018-12-20

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Family Applications (5)

Application Number Title Priority Date Filing Date
JP2017527872A Withdrawn JP2017537905A (ja) 2014-12-02 2015-12-02 アルツハイマー病の治療法
JP2020004429A Withdrawn JP2020055880A (ja) 2014-12-02 2020-01-15 アルツハイマー病の治療法
JP2021127999A Withdrawn JP2021169536A (ja) 2014-12-02 2021-08-04 アルツハイマー病の治療法
JP2022188107A Withdrawn JP2023011002A (ja) 2014-12-02 2022-11-25 アルツハイマー病の治療法
JP2025167679A Pending JP2025182058A (ja) 2014-12-02 2025-10-03 アルツハイマー病の治療法

Family Applications After (4)

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JP2020004429A Withdrawn JP2020055880A (ja) 2014-12-02 2020-01-15 アルツハイマー病の治療法
JP2021127999A Withdrawn JP2021169536A (ja) 2014-12-02 2021-08-04 アルツハイマー病の治療法
JP2022188107A Withdrawn JP2023011002A (ja) 2014-12-02 2022-11-25 アルツハイマー病の治療法
JP2025167679A Pending JP2025182058A (ja) 2014-12-02 2025-10-03 アルツハイマー病の治療法

Country Status (12)

Country Link
US (1) US10842871B2 (enExample)
EP (1) EP3227329A2 (enExample)
JP (5) JP2017537905A (enExample)
KR (3) KR20170088360A (enExample)
AU (3) AU2015356773B2 (enExample)
CA (1) CA2967897A1 (enExample)
EA (1) EA201791199A1 (enExample)
IL (4) IL285722B2 (enExample)
MA (1) MA41115A (enExample)
MX (2) MX385045B (enExample)
WO (1) WO2016087944A2 (enExample)
ZA (1) ZA202107358B (enExample)

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JP2025517623A (ja) * 2022-05-03 2025-06-10 エフ． ホフマン－ラ ロシュ アーゲー アミロイド関連画像異常のインシリコ予測

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JP2023528797A (ja) 2020-05-26 2023-07-06 トゥルーバインディング，インコーポレイテッド ガレクチン－３を遮断することにより炎症性疾患を処置する方法
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TW202313111A (zh) * 2021-06-07 2023-04-01 美商百健Ｍａ公司 治療阿茲海默症之方法
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KR102753583B1 (ko) * 2021-11-11 2025-01-10 의료법인 명지의료재단 Kras 특이적 활성화 t 세포 유도용 항원 조성물
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WO2023210405A1 (ja) 2022-04-25 2023-11-02 公益財団法人東京都医学総合研究所 変異型の神経変性疾患関連タンパク質
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