AU2015356773B2 - Method for treating Alzheimer's disease - Google Patents

Method for treating Alzheimer's disease Download PDF

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Publication number
AU2015356773B2
AU2015356773B2 AU2015356773A AU2015356773A AU2015356773B2 AU 2015356773 B2 AU2015356773 B2 AU 2015356773B2 AU 2015356773 A AU2015356773 A AU 2015356773A AU 2015356773 A AU2015356773 A AU 2015356773A AU 2015356773 B2 AU2015356773 B2 AU 2015356773B2
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human patient
antibody
dose
body weight
patient
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AU2015356773A1 (en
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James L. Ferrero
Jeffrey Joseph Sevigny
Leslie Lugene Williams
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Biogen International Neuroscience GmbH
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Biogen International Neuroscience GmbH
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Priority to AU2021282448A priority Critical patent/AU2021282448A1/en
Priority to AU2025201237A priority patent/AU2025201237A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2015356773A 2014-12-02 2015-12-02 Method for treating Alzheimer's disease Active AU2015356773B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2021282448A AU2021282448A1 (en) 2014-12-02 2021-12-08 Methods for treating Alzheimer's disease
AU2025201237A AU2025201237A1 (en) 2014-12-02 2025-02-21 Methods for treating Alzheimer's disease

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201462086674P 2014-12-02 2014-12-02
US62/086,674 2014-12-02
US201562111874P 2015-02-04 2015-02-04
US62/111,874 2015-02-04
US201562149133P 2015-04-17 2015-04-17
US62/149,133 2015-04-17
US201562195119P 2015-07-21 2015-07-21
US62/195,119 2015-07-21
PCT/IB2015/002465 WO2016087944A2 (en) 2014-12-02 2015-12-02 Method for treating alzheimer's disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2021282448A Division AU2021282448A1 (en) 2014-12-02 2021-12-08 Methods for treating Alzheimer's disease

Publications (2)

Publication Number Publication Date
AU2015356773A1 AU2015356773A1 (en) 2017-05-25
AU2015356773B2 true AU2015356773B2 (en) 2021-09-09

Family

ID=55358010

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2015356773A Active AU2015356773B2 (en) 2014-12-02 2015-12-02 Method for treating Alzheimer's disease
AU2021282448A Abandoned AU2021282448A1 (en) 2014-12-02 2021-12-08 Methods for treating Alzheimer's disease
AU2025201237A Pending AU2025201237A1 (en) 2014-12-02 2025-02-21 Methods for treating Alzheimer's disease

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2021282448A Abandoned AU2021282448A1 (en) 2014-12-02 2021-12-08 Methods for treating Alzheimer's disease
AU2025201237A Pending AU2025201237A1 (en) 2014-12-02 2025-02-21 Methods for treating Alzheimer's disease

Country Status (12)

Country Link
US (1) US10842871B2 (enExample)
EP (1) EP3227329A2 (enExample)
JP (4) JP2017537905A (enExample)
KR (3) KR20240152957A (enExample)
AU (3) AU2015356773B2 (enExample)
CA (1) CA2967897A1 (enExample)
EA (1) EA201791199A1 (enExample)
IL (3) IL311405A (enExample)
MA (1) MA41115A (enExample)
MX (2) MX385045B (enExample)
WO (1) WO2016087944A2 (enExample)
ZA (1) ZA202107358B (enExample)

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US20190167611A1 (en) * 2016-07-29 2019-06-06 Biogen Chesapeake Llc Methods of treating or preventing amyloid related imaging abnormalities associated with alzheimer's disease treatment
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US20240270830A1 (en) * 2021-06-07 2024-08-15 Biogen Ma Inc. Methods for treating alzheimer's disease
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US20230360721A1 (en) * 2022-05-03 2023-11-09 Hoffmann-La Roche Inc. In silico predictions of amyloid-related imaging abnormalities
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