JP2017528519A5 - - Google Patents
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- Publication number
- JP2017528519A5 JP2017528519A5 JP2017530971A JP2017530971A JP2017528519A5 JP 2017528519 A5 JP2017528519 A5 JP 2017528519A5 JP 2017530971 A JP2017530971 A JP 2017530971A JP 2017530971 A JP2017530971 A JP 2017530971A JP 2017528519 A5 JP2017528519 A5 JP 2017528519A5
- Authority
- JP
- Japan
- Prior art keywords
- pyridin
- methoxy
- benzoxazol
- methyl
- methoxypyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462043603P | 2014-08-29 | 2014-08-29 | |
| US62/043,603 | 2014-08-29 | ||
| PCT/US2015/047407 WO2016033445A1 (en) | 2014-08-29 | 2015-08-28 | Probes for imaging huntingtin protein |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020214504A Division JP7126541B2 (ja) | 2014-08-29 | 2020-12-24 | ハンチントンタンパク質のイメージング用プローブ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017528519A JP2017528519A (ja) | 2017-09-28 |
| JP2017528519A5 true JP2017528519A5 (enExample) | 2018-10-04 |
| JP6817207B2 JP6817207B2 (ja) | 2021-01-20 |
Family
ID=55400648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017530971A Active JP6817207B2 (ja) | 2014-08-29 | 2015-08-28 | ハンチントンタンパク質のイメージング用プローブ |
| JP2020214504A Active JP7126541B2 (ja) | 2014-08-29 | 2020-12-24 | ハンチントンタンパク質のイメージング用プローブ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020214504A Active JP7126541B2 (ja) | 2014-08-29 | 2020-12-24 | ハンチントンタンパク質のイメージング用プローブ |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US10479802B2 (enExample) |
| EP (2) | EP3186233B8 (enExample) |
| JP (2) | JP6817207B2 (enExample) |
| KR (2) | KR102456946B1 (enExample) |
| CN (2) | CN107108534B (enExample) |
| AU (1) | AU2015308774B2 (enExample) |
| BR (1) | BR112017004141B8 (enExample) |
| CA (1) | CA2959501C (enExample) |
| DK (1) | DK3186233T3 (enExample) |
| EA (1) | EA035646B1 (enExample) |
| ES (1) | ES2898965T3 (enExample) |
| HR (1) | HRP20211778T1 (enExample) |
| HU (1) | HUE056957T2 (enExample) |
| IL (1) | IL250803B (enExample) |
| MX (2) | MX380810B (enExample) |
| PL (1) | PL3186233T3 (enExample) |
| PT (1) | PT3186233T (enExample) |
| SG (1) | SG11201701600QA (enExample) |
| SI (1) | SI3186233T1 (enExample) |
| WO (1) | WO2016033445A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201701580XA (en) | 2014-08-29 | 2017-03-30 | Chdi Foundation Inc | Probes for imaging huntingtin protein |
| SG11201701578YA (en) | 2014-08-29 | 2017-03-30 | Chdi Foundation Inc | Probes for imaging huntingtin protein |
| PL3197277T3 (pl) | 2014-08-29 | 2022-04-04 | Chdi Foundation, Inc. | Sondy do obrazowania molekularnego białka huntingtyny |
| HRP20211778T1 (hr) * | 2014-08-29 | 2022-03-18 | Chdi Foundation, Inc. | Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina |
| CA2995847C (en) | 2015-08-28 | 2024-05-28 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
| EP3426653B1 (en) | 2016-03-11 | 2021-12-15 | AC Immune SA | Bicyclic compounds for diagnosis and therapy |
| CN107056723A (zh) * | 2017-04-21 | 2017-08-18 | 云南大学 | 一种具有抑制血管内皮生长因子受体信号传导的化合物 |
| MY202326A (en) | 2017-09-14 | 2024-04-24 | Daiichi Sankyo Co Ltd | Compound having cyclic structure |
| BR112020020081A2 (pt) | 2018-04-20 | 2021-01-05 | Bayer Aktiengesellschaft | Derivados de heterocicleno como agentes de controle de pragas |
| WO2019234243A1 (en) | 2018-06-08 | 2019-12-12 | Ac Immune Sa | Novel compounds for diagnosis |
| ES2974634T3 (es) | 2018-12-21 | 2024-06-28 | Celgene Corp | Inhibidores de tienopiridinas de RIPK2 |
| WO2020176424A1 (en) | 2019-02-25 | 2020-09-03 | Chdi Foundation, Inc. | Compounds for targeting mutant huntingtin protein and uses thereof |
| CN111635400A (zh) | 2019-03-02 | 2020-09-08 | 察略盛医药科技(上海)有限公司 | 吡唑并[1,5-a]吡啶类衍生物、及其制备方法和用途 |
| US11992535B2 (en) * | 2019-12-18 | 2024-05-28 | Chdi Foundation, Inc. | Compounds and probes for imaging huntingtin protein |
| US12486274B2 (en) | 2020-01-13 | 2025-12-02 | Verge Analytics, Inc. | Substituted pyrazolo-pyrimidines and uses thereof |
| BR112022021774A2 (pt) | 2020-05-07 | 2022-12-13 | Ac Immune Sa | Compostos para diagnóstico |
| BR112023002139A2 (pt) * | 2020-08-06 | 2023-04-18 | Chdi Foundation Inc | Compostos de heterobiarila e agentes de imageamento para proteína huntingtina |
| MX2023011888A (es) * | 2021-04-08 | 2023-12-06 | Chdi Foundation Inc | Compuestos de isoindolinona y agentes de formación de imágenes para la obtencion de imágenes de la proteína huntingtina. |
| US12606570B2 (en) * | 2021-04-27 | 2026-04-21 | Chdi Foundation, Inc. | Deuterated compounds and imaging agents for imaging huntingtin protein |
| TW202317546A (zh) | 2021-07-09 | 2023-05-01 | 美商普萊克斯姆公司 | 調節ikzf2之芳基化合物及醫藥組合物 |
| KR20240116741A (ko) | 2021-11-10 | 2024-07-30 | 에이씨 이뮨 에스에이 | 디하이드로피롤로[3,4c]-피라졸 유도체 및 진단에서의 그의 용도 |
| EP4430046A1 (en) | 2021-11-10 | 2024-09-18 | AC Immune SA | 4h-imidazo[1,5-b]pyrazole derivatives for diagnosis |
| WO2023083961A1 (en) | 2021-11-10 | 2023-05-19 | Ac Immune Sa | Dihydropyrrolo[3,4-c]pyrazole derivatives and their use in diagnosis |
| TW202425965A (zh) | 2022-09-30 | 2024-07-01 | 日商科研製藥股份有限公司 | 縮環化合物及含有其之醫藥 |
| EP4634190A1 (en) | 2022-12-16 | 2025-10-22 | AC Immune SA | Novel compounds for diagnosis |
| JP2026500313A (ja) | 2022-12-16 | 2026-01-06 | エーシー・イミューン・エス・アー | 診断のための新規化合物 |
| EP4712967A2 (en) * | 2023-05-18 | 2026-03-25 | Enveda Therapeutics, Inc. | G-protein coupled receptor antagonist |
| CN121729415A (zh) | 2023-08-16 | 2026-03-24 | Ac免疫有限公司 | 与α-突触核蛋白结合的用于诊断的化合物 |
| WO2025106920A1 (en) * | 2023-11-15 | 2025-05-22 | Yale University | Parp pet imaging agents and methods of using the same |
| CN119264072B (zh) * | 2024-12-06 | 2025-05-02 | 国科大杭州高等研究院 | 对细胞成像的荧光探针及其合成方法和应用 |
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| US3985755A (en) | 1972-06-02 | 1976-10-12 | E. R. Squibb & Sons, Inc. | Pyridine containing isothiocyanobenzoxazoles |
| US4198416A (en) | 1976-09-30 | 1980-04-15 | Meiji Seika Kaisha, Ltd. | 5-Alkoxy-picolinic esters and anti-hypertensive composition containing 5-alkoxy-picolinic esters |
| DE2909754A1 (de) * | 1979-03-13 | 1980-09-18 | Thomae Gmbh Dr K | Neue benzofuran- und benzothiophenderivate, deren herstellung und deren verwendung als arzneimittel |
| FR2524468B1 (fr) | 1982-04-06 | 1985-10-18 | Sandoz Sa | Nouveaux derives condenses du thiophene, leur preparation et leur utilisation comme azurants optiques |
| JP2869561B2 (ja) * | 1989-05-22 | 1999-03-10 | 大塚製薬株式会社 | 血小板粘着抑制剤 |
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| JP2600644B2 (ja) | 1991-08-16 | 1997-04-16 | 藤沢薬品工業株式会社 | チアゾリルベンゾフラン誘導体 |
| GB9203798D0 (en) | 1992-02-21 | 1992-04-08 | Fujisawa Pharmaceutical Co | Quinolylbenzofuran derivatives,processes for preparation thereof and pharmaceutical composition comprising the same |
| WO1994022846A1 (en) * | 1993-03-30 | 1994-10-13 | Pfizer Inc. | Compounds enhancing antitumor activity of other cytotoxic agents |
| GB9317949D0 (en) * | 1993-08-28 | 1993-10-13 | Stevens Malcolm F G | Benzothiazole compounds |
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| CA2700841A1 (en) | 2007-09-27 | 2009-04-02 | The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services | Isoindoline compounds for the treatment of spinal muscular atrophy and other uses |
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| CN102391260B (zh) * | 2011-09-29 | 2014-12-10 | 上海交通大学 | 3-甲酮-6-取代-苯并呋喃类化合物及其制备方法和用途 |
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| US9370588B2 (en) * | 2013-01-04 | 2016-06-21 | University Of Massachusetts | Luciferin amides |
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| TWI641595B (zh) | 2013-07-17 | 2018-11-21 | 日商大塚製藥股份有限公司 | 氰基三唑化合物類 |
| HRP20211778T1 (hr) | 2014-08-29 | 2022-03-18 | Chdi Foundation, Inc. | Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina |
| PL3197277T3 (pl) | 2014-08-29 | 2022-04-04 | Chdi Foundation, Inc. | Sondy do obrazowania molekularnego białka huntingtyny |
| SG11201701580XA (en) | 2014-08-29 | 2017-03-30 | Chdi Foundation Inc | Probes for imaging huntingtin protein |
| SG11201701578YA (en) | 2014-08-29 | 2017-03-30 | Chdi Foundation Inc | Probes for imaging huntingtin protein |
| CA2995847C (en) | 2015-08-28 | 2024-05-28 | Chdi Foundation, Inc. | Probes for imaging huntingtin protein |
-
2015
- 2015-08-28 HR HRP20211778TT patent/HRP20211778T1/hr unknown
- 2015-08-28 KR KR1020177008383A patent/KR102456946B1/ko active Active
- 2015-08-28 EP EP15836321.8A patent/EP3186233B8/en active Active
- 2015-08-28 JP JP2017530971A patent/JP6817207B2/ja active Active
- 2015-08-28 US US15/507,208 patent/US10479802B2/en active Active
- 2015-08-28 WO PCT/US2015/047407 patent/WO2016033445A1/en not_active Ceased
- 2015-08-28 PT PT158363218T patent/PT3186233T/pt unknown
- 2015-08-28 PL PL15836321T patent/PL3186233T3/pl unknown
- 2015-08-28 SG SG11201701600QA patent/SG11201701600QA/en unknown
- 2015-08-28 DK DK15836321.8T patent/DK3186233T3/da active
- 2015-08-28 EA EA201790407A patent/EA035646B1/ru unknown
- 2015-08-28 CA CA2959501A patent/CA2959501C/en active Active
- 2015-08-28 ES ES15836321T patent/ES2898965T3/es active Active
- 2015-08-28 KR KR1020227035965A patent/KR102586736B1/ko active Active
- 2015-08-28 BR BR112017004141A patent/BR112017004141B8/pt active IP Right Grant
- 2015-08-28 CN CN201580058282.3A patent/CN107108534B/zh active Active
- 2015-08-28 HU HUE15836321A patent/HUE056957T2/hu unknown
- 2015-08-28 EP EP21192872.6A patent/EP4006016A3/en not_active Withdrawn
- 2015-08-28 AU AU2015308774A patent/AU2015308774B2/en active Active
- 2015-08-28 MX MX2017002703A patent/MX380810B/es unknown
- 2015-08-28 CN CN202310475134.8A patent/CN116655618B/zh active Active
- 2015-08-28 SI SI201531751T patent/SI3186233T1/sl unknown
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2017
- 2017-02-27 IL IL250803A patent/IL250803B/en active IP Right Grant
- 2017-02-28 MX MX2021003311A patent/MX2021003311A/es unknown
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2019
- 2019-08-02 US US16/530,594 patent/US11059836B2/en active Active
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2020
- 2020-12-24 JP JP2020214504A patent/JP7126541B2/ja active Active
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2022
- 2022-08-05 US US17/881,895 patent/US12258355B2/en active Active