JP2017523796A5 - - Google Patents

Download PDF

Info

Publication number
JP2017523796A5
JP2017523796A5 JP2017506955A JP2017506955A JP2017523796A5 JP 2017523796 A5 JP2017523796 A5 JP 2017523796A5 JP 2017506955 A JP2017506955 A JP 2017506955A JP 2017506955 A JP2017506955 A JP 2017506955A JP 2017523796 A5 JP2017523796 A5 JP 2017523796A5
Authority
JP
Japan
Prior art keywords
seq
following sequence
encephalitis virus
structural protein
equine encephalitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2017506955A
Other languages
English (en)
Japanese (ja)
Other versions
JP6824154B2 (ja
JP2017523796A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/JP2015/003997 external-priority patent/WO2016021209A1/en
Publication of JP2017523796A publication Critical patent/JP2017523796A/ja
Publication of JP2017523796A5 publication Critical patent/JP2017523796A5/ja
Application granted granted Critical
Publication of JP6824154B2 publication Critical patent/JP6824154B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2017506955A 2014-08-08 2015-08-07 修飾エンベロープタンパク質e3を含むウイルス様粒子 Active JP6824154B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201462035037P 2014-08-08 2014-08-08
US62/035,037 2014-08-08
US201462079128P 2014-11-13 2014-11-13
US62/079,128 2014-11-13
US201562101514P 2015-01-09 2015-01-09
US62/101,514 2015-01-09
US201562120569P 2015-02-25 2015-02-25
US62/120,569 2015-02-25
US201562198949P 2015-07-30 2015-07-30
US62/198,949 2015-07-30
PCT/JP2015/003997 WO2016021209A1 (en) 2014-08-08 2015-08-07 Virus like particle comprising modified envelope protein e3

Publications (3)

Publication Number Publication Date
JP2017523796A JP2017523796A (ja) 2017-08-24
JP2017523796A5 true JP2017523796A5 (enExample) 2018-09-06
JP6824154B2 JP6824154B2 (ja) 2021-02-03

Family

ID=55263499

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017506955A Active JP6824154B2 (ja) 2014-08-08 2015-08-07 修飾エンベロープタンパク質e3を含むウイルス様粒子

Country Status (6)

Country Link
US (1) US9969986B2 (enExample)
EP (1) EP3177720B1 (enExample)
JP (1) JP6824154B2 (enExample)
CN (1) CN106795513B (enExample)
TW (1) TWI720946B (enExample)
WO (1) WO2016021209A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6306518B2 (ja) 2012-02-16 2018-04-04 ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーVLP Therapeutics, LLC ウイルス様粒子組成物
JP6734651B2 (ja) 2013-06-03 2020-08-05 ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーVLP Therapeutics, LLC マラリアワクチン
US9637532B2 (en) 2013-07-12 2017-05-02 Vlp Therapeutics, Llc Virus like particle comprising PD-1 antigen or PD-1 ligand antigen
WO2015054639A1 (en) 2013-10-11 2015-04-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Epstein-barr virus vaccines
US10385101B2 (en) 2014-08-08 2019-08-20 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
US9969986B2 (en) 2014-08-08 2018-05-15 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
EP3191589B1 (en) 2014-09-11 2025-11-26 VLP Therapeutics, Inc. Flavivirus virus like particle
BR112017014219A2 (pt) 2014-12-31 2018-03-06 The Usa As Represented By The Secretary Dept Of Health And Human Services vacinas à base de nanopartículas multivalentes
US10166281B2 (en) 2015-09-04 2019-01-01 Vlp Therapeutics, Llc Method and composition for modulating immune response
WO2017150683A1 (en) * 2016-03-04 2017-09-08 Vlp Therapeutics, Llc Zika virus virus like particle
WO2017221076A1 (en) * 2016-06-24 2017-12-28 Institut Pasteur Compositions and methods comprising measles virus defective interfering particles for the prevention of infectious diseases
IL303650B2 (en) 2016-09-02 2025-02-01 Us Health Stable group 2 trimers from the stem region of influenza hemagglutinin and their uses
JP7346302B2 (ja) * 2017-03-28 2023-09-19 オハイオ・ステイト・イノベーション・ファウンデーション ヒトpd-1ペプチドワクチン及びその使用法
CA3057138A1 (en) 2017-03-28 2018-10-04 Children's Hospital Medical Center Vlp-based monovalent ebola vaccines and methods of making and using same
AR114942A1 (es) * 2017-12-20 2020-11-11 Vlp Therapeutics Llc Partícula de replicón de alfavirus
US12311019B2 (en) 2018-02-07 2025-05-27 Imugene Limited Vaccine composition and uses thereof
WO2019156223A1 (ja) * 2018-02-09 2019-08-15 国立大学法人大阪大学 チクングニアウイルスに対する抗体またはその抗原結合断片、およびその用途
FR3078536A1 (fr) * 2018-03-05 2019-09-06 Peptinov Sas Composition vaccinale anti-pd-1
FR3078535B1 (fr) * 2018-03-05 2024-02-09 Peptinov Sas Composition vaccinale anti-pd-l1
CN109536464B (zh) * 2018-12-10 2022-06-10 中国科学院武汉病毒研究所 一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用
EP4135847A4 (en) 2020-04-17 2024-05-15 VLP Therapeutics, Inc. Coronavirus vaccine
CA3174651A1 (en) 2020-04-30 2021-11-04 Vlp Therapeutics, Inc. Cytokine immunotherapy
US20220347261A1 (en) * 2021-04-23 2022-11-03 Vlp Therapeutics, Inc. Galectin-targeting immunotherapy
CN115466330B (zh) * 2021-06-10 2023-10-20 清华大学 一种基于病毒样颗粒呈递冠状病毒受体结合区的冠状病毒亚单位疫苗
WO2023009505A1 (en) * 2021-07-26 2023-02-02 Beam Therapeutics Inc. Pseudotyped recombinant lyssaviruses for gene therapy
EP4511479A1 (en) * 2022-04-18 2025-02-26 Cyn-K Bio, Inc. Treatment of inflammatory conditions
CN116042657A (zh) * 2023-01-16 2023-05-02 上海复诺健生物科技有限公司 自复制信使核糖核酸疫苗
WO2025084276A1 (ja) * 2023-10-16 2025-04-24 Cyn-Kバイオ株式会社 肥満の処置

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8923123D0 (en) 1989-10-13 1989-11-29 Connaught Lab A vaccine for human immunodeficiency virus
EP1690935A3 (en) 1990-01-12 2008-07-30 Abgenix, Inc. Generation of xenogeneic antibodies
AU2927892A (en) 1991-11-16 1993-06-15 Smithkline Beecham Biologicals (Sa) Hybrid protein between cs from plasmodium and hbsag
US5580773A (en) 1992-06-17 1996-12-03 Korea Green Cross Corporation Chimeric immunogenic gag-V3 virus-like particles of the human immunodeficiency virus (HIV)
CA2143491C (en) 1994-03-01 2011-02-22 Yasumasa Ishida A novel peptide related to human programmed cell death and dna encoding it
EP0854929A1 (en) 1995-09-27 1998-07-29 Medical Research Council Recombinant viruses incorporating a protease cleavable protein
EP1054973A1 (en) 1998-02-11 2000-11-29 Maxygen, Inc. Antigen library immunization
DK1210428T3 (en) 1999-08-23 2015-06-15 Dana Farber Cancer Inst Inc PD-1, a receptor for B7-4 AND USE THEREOF
EP1390398A2 (en) 2001-05-30 2004-02-25 Transgene S.A. Adenovirus protein ix, its domains involved in capsid assembly, transcriptional activity and nuclear reorganization
EP2243493A1 (en) 2002-07-03 2010-10-27 Ono Pharmaceutical Co., Ltd. Immunopotentiative composition
AU2003295470A1 (en) 2002-11-13 2004-06-03 The United States Of America As Represented By The Secretary Of The Navy Methods and compositions for inducing immune responses and protective immunity by priming with alphavirus replicon vaccines
CA2527636A1 (en) * 2003-05-29 2005-01-06 United States Army Medical Research Institute For Infectious Diseases, A Research Laboratory Owned And Operated By The United States Government A Live attenuated viral vaccines for eastern equine encephalitis virus
CN101151272A (zh) 2003-12-01 2008-03-26 陶氏环球技术公司 在假单胞菌中生产重组二十面体病毒样颗粒
MX2007004031A (es) 2004-10-14 2007-11-08 Crucell Holland Bv Vacunas de cebado/refuerzo contra el paludismo.
EP1849799A4 (en) 2005-02-16 2009-05-20 Tokyo Inst Tech MODIFIED VIRUS CAPSID PROTEIN AND APPLICATION THEREOF
MX351401B (es) 2005-06-08 2017-10-13 Dana Farber Cancer Inst Inc Metodos y composiciones para el tratamiento de infecciones persistentes y cancer por inhibicion de la ruta de muerte celular programada (pd-1).
GB0513421D0 (en) 2005-06-30 2005-08-03 Glaxosmithkline Biolog Sa Vaccines
CU23586A1 (es) 2005-11-22 2010-10-30 Ct Ingenieria Genetica Biotech Métodos y proteínas para el tratamiento profiláctico y/o terapéutico de los cuatro serotipos del virus de dengue y otros flavivirus
EP2889309B1 (en) 2006-03-03 2017-12-27 Ono Pharmaceutical Co., Ltd. Multimer of extracellular domain of pd-1 or pd-l1
AU2007291936B2 (en) 2006-08-30 2012-09-27 Artes Biotechnology Gmbh Recombinant proteins and virus like particles comprising L and S polypeptides of avian hepadnaviridae and methods, nucleic acid constructs, vectors and host cells for producing same
EP2225374B1 (en) 2007-11-26 2013-08-14 Novartis AG Methods of generating alphavirus particles
US9353353B2 (en) 2008-11-26 2016-05-31 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Virus-like particles (VLPs) prepared from chikungunya virus structural proteins
SG10201500161XA (en) * 2008-12-09 2015-03-30 Novavax Inc Modified rsv f proteins and methods of their use
EP2477650B8 (en) 2009-09-18 2019-10-09 FRAUNHOFER USA Inc. Virus like particles comprising target proteins fused to plant viral coat proteins
WO2012006180A1 (en) 2010-06-29 2012-01-12 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Hiv immunogens
WO2012023995A1 (en) 2010-08-18 2012-02-23 Takayuki Shiratsuchi Modification of recombinant adenovirus capsid protein with immunogenic plasmodium circumsporozoite protein epitopes
US9487563B2 (en) 2011-01-31 2016-11-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Virus-like particles and methods of use
DK2686020T3 (en) 2011-03-17 2017-05-01 Univ Birmingham REDIRECTED IMMUNTERY
BR112013032251B1 (pt) 2011-06-17 2021-12-07 Bharat Biotech International Limited Composição estável da vacina da cepa do vírus chikungunya inativado com uma ou mais mutações, uso de isolados do vírus chikungunya, e composição combinada da vacina
CN102321639B (zh) 2011-09-08 2013-06-26 中国疾病预防控制中心病毒病预防控制所 基孔肯雅病毒病毒样颗粒的制备方法和应用
BR112014009887A2 (pt) 2011-10-25 2017-04-25 Florida Gulf Coast Univ vacinmas e métodos para desenvolvimento de vacina para indução de imunidade a todos os sorotipos de virus da dengue
JP6306518B2 (ja) 2012-02-16 2018-04-04 ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーVLP Therapeutics, LLC ウイルス様粒子組成物
CN104428312A (zh) 2012-04-02 2015-03-18 北卡罗来纳-查佩尔山大学 用于登革病毒表位的方法和组合物
PT2850431T (pt) 2012-05-16 2018-07-23 Immune Design Corp Vacinas para hsv-2
JP6734651B2 (ja) 2013-06-03 2020-08-05 ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーVLP Therapeutics, LLC マラリアワクチン
US9637532B2 (en) 2013-07-12 2017-05-02 Vlp Therapeutics, Llc Virus like particle comprising PD-1 antigen or PD-1 ligand antigen
WO2015139784A1 (en) 2014-03-18 2015-09-24 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Distinguishing flavivirus infection using a recombinant mutant envelope protein
US9969986B2 (en) 2014-08-08 2018-05-15 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
US10385101B2 (en) 2014-08-08 2019-08-20 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
US9363353B1 (en) 2014-12-04 2016-06-07 Hon Man Ashley Chik Mobile phone docks with multiple circulating phone connectors
BR112017014219A2 (pt) * 2014-12-31 2018-03-06 The Usa As Represented By The Secretary Dept Of Health And Human Services vacinas à base de nanopartículas multivalentes
US20180339038A1 (en) 2015-06-12 2018-11-29 Mie University Human parainfluenza virus type 2 vector and vaccine
US10799575B2 (en) 2015-06-25 2020-10-13 Technovax, Inc. Flavivirus and alphavirus virus-like particles (VLPS)
KR102839410B1 (ko) 2015-07-16 2025-07-28 브하라트 바이오테크 인터내셔날 리미티드 백신 조성물
MA42502A (fr) 2015-07-21 2018-05-30 Modernatx Inc Vaccins contre une maladie infectieuse
CN106085974B (zh) 2016-06-07 2019-08-09 博奥生物集团有限公司 一种寨卡病毒假病毒颗粒及其制备方法

Similar Documents

Publication Publication Date Title
JP2017523796A5 (enExample)
SG11202003746UA (en) Novel, highly active pyrazolo-piperidine substituted indole-2-carboxamides active against the hepatitis b virus (hbv)
ZA202002249B (en) Novel, highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis b virus (hbv)
JP2019194236A5 (enExample)
JP2017048194A5 (enExample)
JP2018024670A5 (enExample)
JP2017514877A5 (enExample)
EA201790630A1 (ru) Способы получения рибозидов
MX2022006652A (es) Proteinas de capside modificadas para un suministro mejorado de vectores de parvovirus.
LT3577124T (lt) Nukleotido hemisulfato druska, skirta hepatito c virusui gydyti
JP2016525888A5 (enExample)
JP2019524645A5 (enExample)
JP2016153424A5 (enExample)
JP2017186358A5 (enExample)
JP2017532302A5 (enExample)
JP2011527560A5 (enExample)
EA201890527A1 (ru) Терапевтические вакцины против hpv18
LT3512863T (lt) 2'-pakeistieji-n6-pakeistieji purino nukleotidai, skirti gydymui rnr virusu
JP2014028813A5 (enExample)
EP3148566C0 (en) LONG SYNTHETIC PEPTIDES (SLP) FOR THERAPEUTIC VACCINATION PURPOSES AGAINST HEPATITIS B VIRUS INFECTION
EP4043031A3 (en) Zika viral antigen constructs
JP2013539454A5 (enExample)
JP2017501211A5 (enExample)
JP2018116258A5 (enExample)
JP2018030858A5 (enExample)