JP2017108751A5 - - Google Patents
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- Publication number
- JP2017108751A5 JP2017108751A5 JP2017023924A JP2017023924A JP2017108751A5 JP 2017108751 A5 JP2017108751 A5 JP 2017108751A5 JP 2017023924 A JP2017023924 A JP 2017023924A JP 2017023924 A JP2017023924 A JP 2017023924A JP 2017108751 A5 JP2017108751 A5 JP 2017108751A5
- Authority
- JP
- Japan
- Prior art keywords
- arg
- etv5
- gene
- exons
- tmprss2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101100012020 Homo sapiens ETV5 gene Proteins 0.000 claims 12
- 230000001105 regulatory effect Effects 0.000 claims 12
- 108700024394 Exon Proteins 0.000 claims 11
- 230000002103 transcriptional effect Effects 0.000 claims 11
- 101000638154 Homo sapiens Transmembrane protease serine 2 Proteins 0.000 claims 10
- 102100031989 Transmembrane protease serine 2 Human genes 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 10
- 239000000523 sample Substances 0.000 claims 10
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 206010060862 Prostate cancer Diseases 0.000 claims 6
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 6
- 230000004927 fusion Effects 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 230000008707 rearrangement Effects 0.000 claims 5
- 108091034117 Oligonucleotide Proteins 0.000 claims 4
- 230000003321 amplification Effects 0.000 claims 4
- 239000012472 biological sample Substances 0.000 claims 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims 4
- 210000002700 urine Anatomy 0.000 claims 3
- 102100039577 ETS translocation variant 5 Human genes 0.000 claims 2
- 101000813745 Homo sapiens ETS translocation variant 5 Proteins 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- 210000002307 prostate Anatomy 0.000 claims 2
- 210000005267 prostate cell Anatomy 0.000 claims 2
- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 claims 2
- 230000028327 secretion Effects 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 108700039691 Genetic Promoter Regions Proteins 0.000 claims 1
- 239000003098 androgen Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 230000008711 chromosomal rearrangement Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000007901 in situ hybridization Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 239000008188 pellet Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 210000000582 semen Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000006228 supernatant Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/825,552 | 2007-07-06 | ||
| US11/825,552 US10041123B2 (en) | 2005-09-12 | 2007-07-06 | Recurrent gene fusions in prostate cancer |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015205414A Division JP2016019542A (ja) | 2007-07-06 | 2015-10-19 | 前立腺癌における再発性遺伝子融合 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017108751A JP2017108751A (ja) | 2017-06-22 |
| JP2017108751A5 true JP2017108751A5 (enExample) | 2017-11-30 |
| JP6404378B2 JP6404378B2 (ja) | 2018-10-10 |
Family
ID=40210565
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515276A Expired - Fee Related JP5529732B2 (ja) | 2007-07-06 | 2008-07-03 | 前立腺癌における再発性遺伝子融合 |
| JP2014016532A Expired - Fee Related JP6035634B2 (ja) | 2007-07-06 | 2014-01-31 | 前立腺癌における再発性遺伝子融合 |
| JP2015205414A Withdrawn JP2016019542A (ja) | 2007-07-06 | 2015-10-19 | 前立腺癌における再発性遺伝子融合 |
| JP2017023924A Expired - Fee Related JP6404378B2 (ja) | 2007-07-06 | 2017-02-13 | 前立腺癌における再発性遺伝子融合 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515276A Expired - Fee Related JP5529732B2 (ja) | 2007-07-06 | 2008-07-03 | 前立腺癌における再発性遺伝子融合 |
| JP2014016532A Expired - Fee Related JP6035634B2 (ja) | 2007-07-06 | 2014-01-31 | 前立腺癌における再発性遺伝子融合 |
| JP2015205414A Withdrawn JP2016019542A (ja) | 2007-07-06 | 2015-10-19 | 前立腺癌における再発性遺伝子融合 |
Country Status (6)
| Country | Link |
|---|---|
| EP (3) | EP2604701B1 (enExample) |
| JP (4) | JP5529732B2 (enExample) |
| AU (1) | AU2008275304B2 (enExample) |
| CA (2) | CA2814246A1 (enExample) |
| WO (1) | WO2009009432A2 (enExample) |
| ZA (1) | ZA201000128B (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7718369B2 (en) | 2005-09-12 | 2010-05-18 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| US9957569B2 (en) | 2005-09-12 | 2018-05-01 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| WO2008039774A1 (en) | 2006-09-25 | 2008-04-03 | Mayo Foundation For Medical Education And Research | Extracellular and membrane-associated prostate cancer markers |
| WO2008058018A2 (en) | 2006-11-02 | 2008-05-15 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| JP5433572B2 (ja) | 2007-07-06 | 2014-03-05 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | Ｍｉｐｏｌ１−ｅｔｖ１遺伝子再編成 |
| JP5529732B2 (ja) * | 2007-07-06 | 2014-06-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 前立腺癌における再発性遺伝子融合 |
| WO2009020521A2 (en) | 2007-08-03 | 2009-02-12 | The Brigham And Women's Hospital, Inc. | Identification and treatment of estrogen responsive prostate tumors |
| EP2806054A1 (en) | 2008-05-28 | 2014-11-26 | Genomedx Biosciences Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| JP5800817B2 (ja) * | 2009-09-17 | 2015-10-28 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 前立腺癌における再発性遺伝子融合 |
| US8945556B2 (en) | 2010-11-19 | 2015-02-03 | The Regents Of The University Of Michigan | RAF gene fusions |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| WO2013090620A1 (en) | 2011-12-13 | 2013-06-20 | Genomedx Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| ES2945036T3 (es) | 2012-08-16 | 2023-06-28 | Veracyte Sd Inc | Pronóstico del cáncer de próstata mediante biomarcadores |
| JP6044935B2 (ja) | 2013-03-11 | 2016-12-14 | 学校法人日本大学 | 新規ｐｉポリアミド |
| KR102241063B1 (ko) | 2013-03-15 | 2021-04-16 | 얀센 파마슈티카 엔.브이. | 예측성 바이오마커에 대한 검정법 |
| EP2975078A1 (en) | 2014-08-14 | 2016-01-20 | Omya International AG | Surface-treated fillers for breathable films |
| WO2017061128A1 (ja) | 2015-10-08 | 2017-04-13 | 凸版印刷株式会社 | ピロールイミダゾール含有ポリアミドを用いた標的二本鎖核酸分子の濃縮方法およびキット |
| US11414708B2 (en) | 2016-08-24 | 2022-08-16 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| AU2018210695B2 (en) | 2017-01-20 | 2024-07-18 | The University Of British Columbia | Molecular subtyping, prognosis, and treatment of bladder cancer |
| US11873532B2 (en) | 2017-03-09 | 2024-01-16 | Decipher Biosciences, Inc. | Subtyping prostate cancer to predict response to hormone therapy |
| WO2018205035A1 (en) | 2017-05-12 | 2018-11-15 | Genomedx Biosciences, Inc | Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness |
| CN114634913A (zh) * | 2022-02-27 | 2022-06-17 | 复旦大学 | 肿瘤硬脑膜转移模型的构建方法 |
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| US7718369B2 (en) * | 2005-09-12 | 2010-05-18 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| JP5529732B2 (ja) * | 2007-07-06 | 2014-06-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 前立腺癌における再発性遺伝子融合 |
-
2008
- 2008-07-03 JP JP2010515276A patent/JP5529732B2/ja not_active Expired - Fee Related
- 2008-07-03 WO PCT/US2008/069204 patent/WO2009009432A2/en not_active Ceased
- 2008-07-03 CA CA2814246A patent/CA2814246A1/en not_active Abandoned
- 2008-07-03 EP EP12179588.4A patent/EP2604701B1/en active Active
- 2008-07-03 EP EP15185944.4A patent/EP3018216B1/en not_active Not-in-force
- 2008-07-03 CA CA2692441A patent/CA2692441C/en not_active Expired - Fee Related
- 2008-07-03 AU AU2008275304A patent/AU2008275304B2/en not_active Ceased
- 2008-07-03 EP EP08772418A patent/EP2167689B1/en active Active
-
2010
- 2010-01-07 ZA ZA2010/00128A patent/ZA201000128B/en unknown
-
2014
- 2014-01-31 JP JP2014016532A patent/JP6035634B2/ja not_active Expired - Fee Related
-
2015
- 2015-10-19 JP JP2015205414A patent/JP2016019542A/ja not_active Withdrawn
-
2017
- 2017-02-13 JP JP2017023924A patent/JP6404378B2/ja not_active Expired - Fee Related
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