JP2015531590A5 - - Google Patents

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Publication number
JP2015531590A5
JP2015531590A5 JP2015524483A JP2015524483A JP2015531590A5 JP 2015531590 A5 JP2015531590 A5 JP 2015531590A5 JP 2015524483 A JP2015524483 A JP 2015524483A JP 2015524483 A JP2015524483 A JP 2015524483A JP 2015531590 A5 JP2015531590 A5 JP 2015531590A5
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JP
Japan
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polypeptide
amino acid
nucleic acid
isolated
mutant
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JP2015524483A
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Japanese (ja)
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JP2015531590A (ja
JP6297556B2 (ja
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Priority claimed from PCT/US2013/052395 external-priority patent/WO2014018926A1/en
Publication of JP2015531590A publication Critical patent/JP2015531590A/ja
Publication of JP2015531590A5 publication Critical patent/JP2015531590A5/ja
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Publication of JP6297556B2 publication Critical patent/JP6297556B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015524483A 2012-07-27 2013-07-26 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物 Expired - Fee Related JP6297556B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261676842P 2012-07-27 2012-07-27
US61/676,842 2012-07-27
US201361783763P 2013-03-14 2013-03-14
US61/783,763 2013-03-14
US201361829123P 2013-05-30 2013-05-30
US61/829,123 2013-05-30
PCT/US2013/052395 WO2014018926A1 (en) 2012-07-27 2013-07-26 Methods and compositions for determining resistance to androgen receptor therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018028558A Division JP6592545B2 (ja) 2012-07-27 2018-02-21 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物

Publications (3)

Publication Number Publication Date
JP2015531590A JP2015531590A (ja) 2015-11-05
JP2015531590A5 true JP2015531590A5 (enExample) 2016-09-08
JP6297556B2 JP6297556B2 (ja) 2018-03-20

Family

ID=48948536

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015524483A Expired - Fee Related JP6297556B2 (ja) 2012-07-27 2013-07-26 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物
JP2018028558A Expired - Fee Related JP6592545B2 (ja) 2012-07-27 2018-02-21 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物
JP2019171022A Ceased JP2020072655A (ja) 2012-07-27 2019-09-20 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018028558A Expired - Fee Related JP6592545B2 (ja) 2012-07-27 2018-02-21 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物
JP2019171022A Ceased JP2020072655A (ja) 2012-07-27 2019-09-20 アンドロゲン受容体治療に対する抵抗性を判定する方法及び組成物

Country Status (34)

Country Link
US (2) US9617602B2 (enExample)
EP (2) EP3653733A1 (enExample)
JP (3) JP6297556B2 (enExample)
KR (2) KR20210012064A (enExample)
CN (3) CN104685072A (enExample)
AU (3) AU2013295543B2 (enExample)
BR (2) BR122017017921A2 (enExample)
CA (1) CA2879926A1 (enExample)
CL (1) CL2015000194A1 (enExample)
CO (1) CO7280477A2 (enExample)
CR (1) CR20150022A (enExample)
CY (1) CY1122651T1 (enExample)
DK (1) DK2877599T3 (enExample)
EA (2) EA035535B1 (enExample)
EC (1) ECSP15007420A (enExample)
ES (1) ES2764381T3 (enExample)
GT (1) GT201500019A (enExample)
HR (1) HRP20192342T1 (enExample)
HU (1) HUE047781T2 (enExample)
IL (2) IL236844B (enExample)
LT (1) LT2877599T (enExample)
MX (2) MX370507B (enExample)
NI (1) NI201500004A (enExample)
NZ (4) NZ744288A (enExample)
PE (3) PE20190574A1 (enExample)
PH (2) PH12015500175A1 (enExample)
PL (1) PL2877599T3 (enExample)
PT (1) PT2877599T (enExample)
RS (1) RS59812B1 (enExample)
SG (2) SG11201500184TA (enExample)
SI (1) SI2877599T1 (enExample)
SM (1) SMT201900735T1 (enExample)
UA (1) UA118178C2 (enExample)
WO (1) WO2014018926A1 (enExample)

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EP2839028B1 (en) 2012-04-20 2016-12-28 Cepheid Methods of detecting bladder cancer
AU2013334075B2 (en) * 2012-10-26 2018-11-29 Memorial Sloan-Kettering Cancer Center Androgen receptor variants and methods for making and using
EP2959013A2 (en) * 2013-02-25 2015-12-30 Novartis AG Novel androgen receptor mutation
WO2014138396A1 (en) * 2013-03-06 2014-09-12 Cepheid Methods of detecting bladder cancer
CA2904170A1 (en) 2013-03-14 2014-09-25 University Of Maryland, Baltimore Androgen receptor down-regulating agents and uses thereof
KR20160058774A (ko) 2013-08-12 2016-05-25 토카이 파마슈티컬, 아이엔씨. 안드로겐-표적 치료제를 이용하는 종양 질환 치료를 위한 바이오마커
AU2014336638C1 (en) 2013-10-18 2020-09-17 Novartis Ag Labeled inhibitors of prostate specific membrane antigen (PSMA), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
CN106102716A (zh) * 2014-02-05 2016-11-09 斯洛文尼亚莱柯制药股份有限公司 雄激素受体拮抗剂的固体药物组合物
WO2015179404A1 (en) * 2014-05-19 2015-11-26 The Johns Hopkins University Methods for identifying androgen receptor splice variants in subjects having castration resistant prostate cancer
WO2016033114A1 (en) * 2014-08-25 2016-03-03 The Johns Hopkins University Methods and compositions related to prostate cancer therapeutics
CN108882893A (zh) 2016-03-29 2018-11-23 豪夫迈·罗氏有限公司 操作用于接收分析物数据的接收器的方法,接收器和计算机程序产品
WO2017181161A1 (en) * 2016-04-15 2017-10-19 Predicine, Inc. Systems and methods for detecting genetic alterations
CN106405085B (zh) * 2016-08-31 2018-03-27 天津市泌尿外科研究所 用于检测去势抵抗性前列腺癌的elisa试剂盒及使用方法
CN106290919B (zh) * 2016-08-31 2018-03-27 天津市泌尿外科研究所 用于检测去势抵抗性前列腺癌的elisa试剂盒及使用方法
CN106198985B (zh) * 2016-08-31 2018-03-27 天津市泌尿外科研究所 用于检测去势抵抗性前列腺癌的elisa试剂盒及使用方法
CN106526185B (zh) * 2016-10-28 2018-03-30 拜尔康(天津)医药科技有限公司 用于检测去势抵抗性前列腺癌的elisa试剂盒及检测方法
KR20220028178A (ko) * 2016-12-16 2022-03-08 강푸 바이오파마슈티칼즈 리미티드 조성물, 이의 적용 및 치료 방법
CN111372597A (zh) * 2017-10-19 2020-07-03 耶鲁大学 通过药用草药提取物及其组合物抑制雄激素受体
CN108018342A (zh) * 2017-12-04 2018-05-11 合肥艾迪康临床检验所有限公司 检测ar基因突变的引物和方法
CN109115742A (zh) * 2018-09-05 2019-01-01 中国农业科学院农业质量标准与检测技术研究所 一种抗雄激素效应的检测方法
CN109321569B (zh) * 2018-10-29 2022-04-12 迈杰转化医学研究(苏州)有限公司 一种引物探针组合物及其应用
KR102473989B1 (ko) 2018-11-28 2022-12-07 (주)바이오니아 안드로젠 수용체 특이적 서열을 포함하는 이중나선 올리고뉴클레오티드 구조체, 및 이를 포함하는 탈모 예방 및 발모용 조성물
EP4034114A4 (en) * 2019-09-23 2023-07-26 Accutar Biotechnology Inc. Novel ureas having androgen receptor degradation activity and uses thereof
GB201914296D0 (en) * 2019-10-03 2019-11-20 Univ Oxford Innovation Ltd Treatment
WO2021110731A1 (en) * 2019-12-03 2021-06-10 Bayer Aktiengesellschaft Method for determining the response of prostate cancer patients to treatment with androgen receptor antagonists based on gene expression changes or super-enhancer protein-binding profiles
CN113533730B (zh) * 2021-07-23 2022-09-06 南方医科大学深圳医院 一种血浆外泌体标志物组合及其应用
WO2024001989A1 (en) * 2022-06-27 2024-01-04 Etern Biopharma (Shanghai) Co., Ltd. Compositions and methods for modulating molecules
CN117860773B (zh) * 2023-11-28 2024-07-16 四川大学华西医院 促进ar基因甲基化的药物及其在预防或治疗雄性激素脱发中的用途
CN117778322B (zh) * 2023-12-17 2025-02-07 苏州拓维生物技术有限公司 一种对恩杂鲁胺耐药的细胞系的筛选方法及其应用
CN121065176A (zh) * 2025-04-14 2025-12-05 羿美诚健(上海)生物医药有限公司 靶向雄激素受体的小核酸及其药物组合物和用途

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US8133724B2 (en) * 2008-09-17 2012-03-13 University Of Maryland, Baltimore Human androgen receptor alternative splice variants as biomarkers and therapeutic targets
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