CR20150022A - Métodos y composiciones para determinar la resistencia a la terapia con receptor de andrógeno - Google Patents

Métodos y composiciones para determinar la resistencia a la terapia con receptor de andrógeno

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Publication number
CR20150022A
CR20150022A CR20150022A CR20150022A CR20150022A CR 20150022 A CR20150022 A CR 20150022A CR 20150022 A CR20150022 A CR 20150022A CR 20150022 A CR20150022 A CR 20150022A CR 20150022 A CR20150022 A CR 20150022A
Authority
CR
Costa Rica
Prior art keywords
therapy
compositions
resistance
methods
androgen
Prior art date
Application number
CR20150022A
Other languages
English (en)
Inventor
James David Joseph
Jeffrey H Hager
John Lee Sensintaffar
Nhin Lu
Jing Qian
Nicholas D Smith
Original Assignee
Aragon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aragon Pharmaceuticals Inc filed Critical Aragon Pharmaceuticals Inc
Publication of CR20150022A publication Critical patent/CR20150022A/es

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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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Abstract

En la presente descripción se describen polipéptidos del receptor de andrógeno modificado que son resistentes a la inhibición por un inhibidor del receptor de androgeno.
CR20150022A 2012-07-27 2015-01-21 Métodos y composiciones para determinar la resistencia a la terapia con receptor de andrógeno CR20150022A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261676842P 2012-07-27 2012-07-27
US201361783763P 2013-03-14 2013-03-14
US201361829123P 2013-05-30 2013-05-30
PCT/US2013/052395 WO2014018926A1 (en) 2012-07-27 2013-07-26 Methods and compositions for determining resistance to androgen receptor therapy

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CR20150022A true CR20150022A (es) 2015-04-30

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CR20150022A CR20150022A (es) 2012-07-27 2015-01-21 Métodos y composiciones para determinar la resistencia a la terapia con receptor de andrógeno

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EP2300041B1 (en) 2008-04-16 2016-01-27 The Johns Hopkins University Method for determining risk of recurrence of prostate cancer
PE20150099A1 (es) 2011-12-16 2015-01-30 Olema Pharmaceuticals Inc Compuestos novedosos de benzopirano, composiciones y usos de los mismos
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