JP2016533170A5 - - Google Patents
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- JP2016533170A5 JP2016533170A5 JP2016519763A JP2016519763A JP2016533170A5 JP 2016533170 A5 JP2016533170 A5 JP 2016533170A5 JP 2016519763 A JP2016519763 A JP 2016519763A JP 2016519763 A JP2016519763 A JP 2016519763A JP 2016533170 A5 JP2016533170 A5 JP 2016533170A5
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- 239000012634 fragment Substances 0.000 claims 27
- 125000003275 alpha amino acid group Chemical group 0.000 claims 17
- 238000001514 detection method Methods 0.000 claims 11
- 101000664703 Homo sapiens Transcription factor SOX-10 Proteins 0.000 claims 6
- 102100038808 Transcription factor SOX-10 Human genes 0.000 claims 6
- 102000002260 Alkaline Phosphatase Human genes 0.000 claims 4
- 108020004774 Alkaline Phosphatase Proteins 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 101000578784 Homo sapiens Melanoma antigen recognized by T-cells 1 Proteins 0.000 claims 4
- 108010001336 Horseradish Peroxidase Proteins 0.000 claims 4
- 102100028389 Melanoma antigen recognized by T-cells 1 Human genes 0.000 claims 4
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical group 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 102000003425 Tyrosinase Human genes 0.000 claims 3
- 108060008724 Tyrosinase Proteins 0.000 claims 3
- 210000004408 hybridoma Anatomy 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- QRXMUCSWCMTJGU-UHFFFAOYSA-L (5-bromo-4-chloro-1h-indol-3-yl) phosphate Chemical compound C1=C(Br)C(Cl)=C2C(OP([O-])(=O)[O-])=CNC2=C1 QRXMUCSWCMTJGU-UHFFFAOYSA-L 0.000 claims 2
- UAIUNKRWKOVEES-UHFFFAOYSA-N 3,3',5,5'-tetramethylbenzidine Chemical compound CC1=C(N)C(C)=CC(C=2C=C(C)C(N)=C(C)C=2)=C1 UAIUNKRWKOVEES-UHFFFAOYSA-N 0.000 claims 2
- HSTOKWSFWGCZMH-UHFFFAOYSA-N 3,3'-diaminobenzidine Chemical compound C1=C(N)C(N)=CC=C1C1=CC=C(N)C(N)=C1 HSTOKWSFWGCZMH-UHFFFAOYSA-N 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- OXEUETBFKVCRNP-UHFFFAOYSA-N 9-ethyl-3-carbazolamine Chemical compound NC1=CC=C2N(CC)C3=CC=CC=C3C2=C1 OXEUETBFKVCRNP-UHFFFAOYSA-N 0.000 claims 2
- 241000283707 Capra Species 0.000 claims 2
- 241000287828 Gallus gallus Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 241000283973 Oryctolagus cuniculus Species 0.000 claims 2
- WLDHEUZGFKACJH-UHFFFAOYSA-K amaranth Chemical compound [Na+].[Na+].[Na+].C12=CC=C(S([O-])(=O)=O)C=C2C=C(S([O-])(=O)=O)C(O)=C1N=NC1=CC=C(S([O-])(=O)=O)C2=CC=CC=C12 WLDHEUZGFKACJH-UHFFFAOYSA-K 0.000 claims 2
- 102000005936 beta-Galactosidase Human genes 0.000 claims 2
- 108010005774 beta-Galactosidase Proteins 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 235000013330 chicken meat Nutrition 0.000 claims 2
- 229940039227 diagnostic agent Drugs 0.000 claims 2
- 239000000032 diagnostic agent Substances 0.000 claims 2
- 239000007850 fluorescent dye Substances 0.000 claims 2
- 239000006249 magnetic particle Substances 0.000 claims 2
- 201000001441 melanoma Diseases 0.000 claims 2
- 230000002285 radioactive effect Effects 0.000 claims 2
- -1 radioisotope Substances 0.000 claims 2
- 241000894007 species Species 0.000 claims 2
- 238000010186 staining Methods 0.000 claims 2
- 239000003053 toxin Substances 0.000 claims 2
- 231100000765 toxin Toxicity 0.000 claims 2
- 238000012800 visualization Methods 0.000 claims 2
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 241000283086 Equidae Species 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 208000018142 Leiomyosarcoma Diseases 0.000 claims 1
- 206010027145 Melanocytic naevus Diseases 0.000 claims 1
- 241001529936 Murinae Species 0.000 claims 1
- 241000699670 Mus sp. Species 0.000 claims 1
- 208000007256 Nevus Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 238000012137 double-staining Methods 0.000 claims 1
- 230000003352 fibrogenic effect Effects 0.000 claims 1
- 201000010078 malignant spindle cell melanoma Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 201000009410 rhabdomyosarcoma Diseases 0.000 claims 1
- 208000019798 spindle cell melanoma Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361886488P | 2013-10-03 | 2013-10-03 | |
| US61/886,488 | 2013-10-03 | ||
| US201461941907P | 2014-02-19 | 2014-02-19 | |
| US61/941,907 | 2014-02-19 | ||
| PCT/US2014/059162 WO2015051320A2 (en) | 2013-10-03 | 2014-10-03 | Anti-sox10 antibody systems and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016533170A JP2016533170A (ja) | 2016-10-27 |
| JP2016533170A5 true JP2016533170A5 (cg-RX-API-DMAC7.html) | 2017-11-16 |
| JP6506267B2 JP6506267B2 (ja) | 2019-04-24 |
Family
ID=52779309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016519763A Active JP6506267B2 (ja) | 2013-10-03 | 2014-10-03 | 抗ｓｏｘ１０抗体のシステムおよび方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9816997B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3052522B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6506267B2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3052522T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2765423T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015051320A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8852592B2 (en) | 2011-05-10 | 2014-10-07 | Biocare Medical, Llc | Systems and methods for anti-PAX8 antibodies |
| US10316103B1 (en) | 2012-03-30 | 2019-06-11 | Biocare Medical, Llc | Systems and methods for anti-Uroplakin III antibodies |
| EP2900265B1 (en) | 2012-09-27 | 2018-05-30 | Biocare Medical, LLC | Anti-uroplakin ii antibodies systems and methods |
| US10429390B2 (en) | 2012-12-18 | 2019-10-01 | Biocare Medical, Llc | Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer |
| JP6445467B2 (ja) | 2013-02-28 | 2019-01-09 | バイオケア メディカル， エルエルシー | 抗ｐ４０抗体システムおよび方法 |
| ES2765423T3 (es) | 2013-10-03 | 2020-06-09 | Biocare Medical Llc | Sistemas y procedimientos de anticuerpos anti-SOX10 |
| CN105238793B (zh) * | 2015-11-25 | 2019-04-16 | 中国人民解放军第三军医大学 | 引起内耳Mondini畸形的猪SOX10突变基因及其应用 |
| US10969392B2 (en) * | 2015-12-10 | 2021-04-06 | Vanderbilt University | Methods and systems for predicting response to immunotherapies for treatment of cancer |
| CN106896104A (zh) * | 2017-01-05 | 2017-06-27 | Teco诊断有限公司 | 一种生物样品测试盒及其检测方法 |
| CN114720689B (zh) * | 2022-04-07 | 2024-04-09 | 南京中医药大学 | 半夏凝集素蛋白酶联免疫Elisa试剂盒及应用 |
| CN115724965A (zh) * | 2022-07-13 | 2023-03-03 | 浙江欧赛思生物科技有限公司 | 一种豚鼠sox10多克隆抗体的制备方法及其应用 |
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| EP2900265B1 (en) | 2012-09-27 | 2018-05-30 | Biocare Medical, LLC | Anti-uroplakin ii antibodies systems and methods |
| US10429390B2 (en) | 2012-12-18 | 2019-10-01 | Biocare Medical, Llc | Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer |
| JP6445467B2 (ja) | 2013-02-28 | 2019-01-09 | バイオケア メディカル， エルエルシー | 抗ｐ４０抗体システムおよび方法 |
| ES2765423T3 (es) | 2013-10-03 | 2020-06-09 | Biocare Medical Llc | Sistemas y procedimientos de anticuerpos anti-SOX10 |
-
2014
- 2014-10-03 ES ES14850426T patent/ES2765423T3/es active Active
- 2014-10-03 US US15/026,904 patent/US9816997B2/en active Active
- 2014-10-03 WO PCT/US2014/059162 patent/WO2015051320A2/en not_active Ceased
- 2014-10-03 JP JP2016519763A patent/JP6506267B2/ja active Active
- 2014-10-03 EP EP14850426.9A patent/EP3052522B1/en active Active
- 2014-10-03 DK DK14850426.9T patent/DK3052522T3/da active
-
2017
- 2017-11-13 US US15/811,458 patent/US10295542B2/en active Active
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