MX2018008809A - Anticuerpos monoclonales especificos para el antigeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, utiles para la deteccion y el diagnostico de la infeccion causada por adv. - Google Patents
Anticuerpos monoclonales especificos para el antigeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, utiles para la deteccion y el diagnostico de la infeccion causada por adv.Info
- Publication number
- MX2018008809A MX2018008809A MX2018008809A MX2018008809A MX2018008809A MX 2018008809 A MX2018008809 A MX 2018008809A MX 2018008809 A MX2018008809 A MX 2018008809A MX 2018008809 A MX2018008809 A MX 2018008809A MX 2018008809 A MX2018008809 A MX 2018008809A
- Authority
- MX
- Mexico
- Prior art keywords
- adv
- monoclonal antibodies
- infection
- useful
- seq
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a anticuerpos monoclonales, o fragmentos de los mismos, que reconocen la proteína pIII del Adenovirus (ADV), útiles para el desarrollo de métodos de diagnóstico de infección por ADV en humanos. En particular se refiere a un anticuerpo monoclonal o un fragmento de él que comprende una región variable de la cadena pesada que tiene una secuencia con al menos un 90%, 95% o 99% de identidad con la SEQ ID No: 1 o SEQ ID No: 5 y una región variable de la cadena liviana que tiene una secuencia con al menos un 90%, 95% o 99% de identidad con la SEQ ID No: 2 o SEQ ID No: 6. También se dirige a las secuencias nucleotídicas que definen dichos anticuerpos, métodos in vitro y/o ex vivo de diagnóstico de infección por ADV en una muestra biológica que utilizan dichos anticuerpos monoclonales, y kits de diagnóstico para detectar ADV, que comprenden al menos un anticuerpo monoclonal contra ADV de acuerdo a lo descrito anteriormente.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2016000164A CL2016000164A1 (es) | 2016-01-21 | 2016-01-21 | Anticuerpos monoclonales específicos para el antígeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por adv. |
| PCT/IB2017/050312 WO2017125892A2 (es) | 2016-01-21 | 2017-01-20 | Anticuerpos monoclonales específicos para el antígeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por adv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018008809A true MX2018008809A (es) | 2018-11-29 |
Family
ID=56610130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018008809A MX2018008809A (es) | 2016-01-21 | 2017-01-20 | Anticuerpos monoclonales especificos para el antigeno piii de adenovirus humano (adv), producidos y secretados por hibridomas celulares, utiles para la deteccion y el diagnostico de la infeccion causada por adv. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10766948B2 (es) |
| EP (2) | EP3406262B1 (es) |
| CN (1) | CN108697796B (es) |
| AR (1) | AR107440A1 (es) |
| BR (1) | BR112018014538A2 (es) |
| CA (1) | CA3011569A1 (es) |
| CL (1) | CL2016000164A1 (es) |
| ES (1) | ES2898068T3 (es) |
| MX (1) | MX2018008809A (es) |
| PE (1) | PE20181498A1 (es) |
| PT (1) | PT3406262T (es) |
| UY (1) | UY37082A (es) |
| WO (1) | WO2017125892A2 (es) |
| ZA (1) | ZA201804705B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2018003869A1 (es) * | 2018-12-28 | 2021-01-15 | Univ Pontificia Catolica Chile | Anticuerpos monoclonales específicos para la proteína quimérica l del virus de la parainfluenza humana (piv), secuencias nucleotídicas; método y kit de diagnóstico de infección producida por piv |
| CN113354727B (zh) * | 2021-08-10 | 2021-11-02 | 北京溯本源和生物科技有限公司 | 一组同时检测b/c/e组腺病毒的单克隆抗体和试纸条 |
| CN118027181A (zh) * | 2023-06-14 | 2024-05-14 | 珠海重链生物科技有限公司 | 六邻体蛋白抗体及其应用 |
| CN117586385B (zh) * | 2023-11-23 | 2024-05-17 | 广州医科大学附属第一医院（广州呼吸中心） | 抗人4型腺病毒中和抗体及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4487829A (en) | 1982-03-23 | 1984-12-11 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies against adenoviruses |
| US6248514B1 (en) * | 1996-07-09 | 2001-06-19 | Canji, Inc. | Methods for measuring viral infectivity |
| CN1207569C (zh) | 1997-08-04 | 2005-06-22 | 株式会社先端生命科学研究所 | 用于测定含病毒样品的方法、病毒测定方法和诊断试剂盒 |
| AU2001277531A1 (en) * | 2000-07-10 | 2002-01-21 | Novartis Ag | Bifunctional molecules and vectors complexed therewith for targeted gene delivery |
| WO2005023848A2 (en) * | 2003-09-09 | 2005-03-17 | Gardner, Rebecca, Katherine | Adenoviral epitopes |
| CA2548942C (en) * | 2003-12-05 | 2013-10-15 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Health | Anti-sars monoclonal antibodies |
| US8003108B2 (en) * | 2005-05-03 | 2011-08-23 | Amgen Inc. | Sclerostin epitopes |
| GB2462048B (en) * | 2007-05-03 | 2012-03-21 | Agency Science Tech & Res | Antibodies binding to an intracellular prl-1 or prl-3 polypeptide |
-
2016
- 2016-01-21 CL CL2016000164A patent/CL2016000164A1/es unknown
-
2017
- 2017-01-20 US US16/070,730 patent/US10766948B2/en active Active
- 2017-01-20 CN CN201780007470.2A patent/CN108697796B/zh active Active
- 2017-01-20 MX MX2018008809A patent/MX2018008809A/es unknown
- 2017-01-20 EP EP17741167.5A patent/EP3406262B1/en active Active
- 2017-01-20 BR BR112018014538-6A patent/BR112018014538A2/pt unknown
- 2017-01-20 WO PCT/IB2017/050312 patent/WO2017125892A2/es active Application Filing
- 2017-01-20 UY UY0001037082A patent/UY37082A/es not_active Application Discontinuation
- 2017-01-20 CA CA3011569A patent/CA3011569A1/en active Pending
- 2017-01-20 ES ES17741167T patent/ES2898068T3/es active Active
- 2017-01-20 PT PT177411675T patent/PT3406262T/pt unknown
- 2017-01-20 PE PE2018001294A patent/PE20181498A1/es unknown
- 2017-01-20 EP EP20166433.1A patent/EP3756685A1/en active Pending
- 2017-01-20 AR ARP170100158A patent/AR107440A1/es unknown
-
2018
- 2018-07-13 ZA ZA2018/04705A patent/ZA201804705B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR107440A1 (es) | 2018-05-02 |
| PT3406262T (pt) | 2021-11-03 |
| UY37082A (es) | 2017-04-28 |
| BR112018014538A2 (pt) | 2018-12-26 |
| US20190048065A1 (en) | 2019-02-14 |
| CN108697796B (zh) | 2023-01-10 |
| EP3406262B1 (en) | 2021-07-28 |
| WO2017125892A2 (es) | 2017-07-27 |
| ES2898068T3 (es) | 2022-03-03 |
| CN108697796A (zh) | 2018-10-23 |
| CA3011569A1 (en) | 2017-07-27 |
| EP3406262A2 (en) | 2018-11-28 |
| WO2017125892A3 (es) | 2018-04-12 |
| EP3406262A4 (en) | 2019-01-09 |
| CL2016000164A1 (es) | 2016-07-29 |
| ZA201804705B (en) | 2019-09-25 |
| PE20181498A1 (es) | 2018-09-18 |
| EP3756685A1 (en) | 2020-12-30 |
| US10766948B2 (en) | 2020-09-08 |
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