JP2016527215A5 - - Google Patents
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- JP2016527215A5 JP2016527215A5 JP2016524705A JP2016524705A JP2016527215A5 JP 2016527215 A5 JP2016527215 A5 JP 2016527215A5 JP 2016524705 A JP2016524705 A JP 2016524705A JP 2016524705 A JP2016524705 A JP 2016524705A JP 2016527215 A5 JP2016527215 A5 JP 2016527215A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- formula
- optionally substituted
- oxygen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 COC(C(C(Nc(cc1)ccc1C(*)=O)=O)NC(c(cc1)ccc1NC(c(cc1)ccc1[N+]([O-])=O)=O)=O)C([Rn])=O Chemical compound COC(C(C(Nc(cc1)ccc1C(*)=O)=O)NC(c(cc1)ccc1NC(c(cc1)ccc1[N+]([O-])=O)=O)=O)C([Rn])=O 0.000 description 2
- WMLWGVVLDSEQNF-UHFFFAOYSA-N CC(C)Oc(c(NC(c(cc1)ccc1NC(C(C(C(N)=O)OC)NC(c(cc1)ccc1NC(c(cc1)ccc1[N+]([O-])=O)=O)=O)=O)=O)ccc1C(Nc(c(OC)c2)ccc2C(O)=O)=O)c1O Chemical compound CC(C)Oc(c(NC(c(cc1)ccc1NC(C(C(C(N)=O)OC)NC(c(cc1)ccc1NC(c(cc1)ccc1[N+]([O-])=O)=O)=O)=O)=O)ccc1C(Nc(c(OC)c2)ccc2C(O)=O)=O)c1O WMLWGVVLDSEQNF-UHFFFAOYSA-N 0.000 description 1
- NGSYXDCEERWVTK-UHFFFAOYSA-N CC(C)Oc(c(NC(c(cc1)ccc1NC(C(C(C(N)=O)OC)NC(c(cc1)ccc1NC(c(cc1)ccc1[N+]([O-])=O)=O)=O)=O)=O)ccc1C(Nc(cc2)ccc2C(O)=O)=O)c1O Chemical compound CC(C)Oc(c(NC(c(cc1)ccc1NC(C(C(C(N)=O)OC)NC(c(cc1)ccc1NC(c(cc1)ccc1[N+]([O-])=O)=O)=O)=O)=O)ccc1C(Nc(cc2)ccc2C(O)=O)=O)c1O NGSYXDCEERWVTK-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13003539 | 2013-07-12 | ||
| EP13003539.7 | 2013-07-12 | ||
| PCT/EP2014/001925 WO2015003816A2 (en) | 2013-07-12 | 2014-07-14 | Cystobactamides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016527215A JP2016527215A (ja) | 2016-09-08 |
| JP2016527215A5 true JP2016527215A5 (enExample) | 2017-08-03 |
| JP6730183B2 JP6730183B2 (ja) | 2020-07-29 |
Family
ID=48792948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016524705A Active JP6730183B2 (ja) | 2013-07-12 | 2014-07-14 | シストバクトアミド（Ｃｙｓｔｏｂａｃｔａｍｉｄｅｓ） |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20160145304A1 (enExample) |
| EP (1) | EP3019615B1 (enExample) |
| JP (1) | JP6730183B2 (enExample) |
| CN (1) | CN105793424B (enExample) |
| AU (1) | AU2014289663B2 (enExample) |
| CA (1) | CA2917767C (enExample) |
| WO (1) | WO2015003816A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2917767C (en) | 2013-07-12 | 2022-05-03 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Cystobactamides |
| GB201402277D0 (en) | 2014-02-10 | 2014-03-26 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| US20170204052A1 (en) * | 2014-05-15 | 2017-07-20 | Korea Research Institute Of Bioscience And Biotechnology | Novel antimicrobial compound and use thereof |
| CA2968270C (en) * | 2014-11-26 | 2022-11-01 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Further natural cystobactamides, synthetic derivatives thereof, and use thereof in treating bacterial infections |
| CN105712894A (zh) * | 2016-03-23 | 2016-06-29 | 叶芳 | 一种3-甲氧基-4-氨基苯甲酸及其制备方法 |
| WO2018062422A1 (ja) * | 2016-09-28 | 2018-04-05 | 日産化学工業株式会社 | ジアミンおよびその利用 |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| AU2018300150A1 (en) | 2017-07-11 | 2020-01-30 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| EP3655394B1 (en) * | 2017-07-18 | 2023-11-22 | Technische Universität Berlin | Novel albicidin derivatives, their use and synthesis |
| US11034648B2 (en) * | 2017-08-23 | 2021-06-15 | Helmholtz-Zentrum Für | Cystobactamide derivatives |
| AU2018346597B2 (en) | 2017-10-06 | 2023-07-13 | Forma Therapeutics, Inc. | Inhibiting Ubiquitin Specific Peptidase 30 |
| IL316472A (en) | 2018-01-10 | 2024-12-01 | Recurium Ip Holdings Llc | Benzamide compounds |
| WO2019160882A1 (en) | 2018-02-13 | 2019-08-22 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| KR102591947B1 (ko) | 2018-04-19 | 2023-10-25 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| IL278291B2 (en) | 2018-05-17 | 2023-10-01 | Forma Therapeutics Inc | Condensed bicyclic compounds are useful as ubiquitin-specific peptidase 30 inhibitors |
| PE20210642A1 (es) | 2018-07-13 | 2021-03-23 | Gilead Sciences Inc | Inhibidores de pd-1/pd-l1 |
| EP4218934B1 (en) | 2018-10-05 | 2025-06-18 | Forma Therapeutics, Inc. | Inhibiting ubiquitin-specific protease 30 (usp30) |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| WO2020146682A1 (en) | 2019-01-10 | 2020-07-16 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| WO2020146612A1 (en) | 2019-01-10 | 2020-07-16 | Vertex Pharmaceuticals Incorporated | Esters and carbamates as modulators of sodium channels |
| AU2020300619A1 (en) | 2019-07-03 | 2022-01-27 | Sumitomo Pharma Oncology, Inc. | Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof |
| PH12022551379A1 (en) | 2019-12-06 | 2023-05-03 | Vertex Pharma | Substituted tetrahydrofurans as modulators of sodium channels |
| EP4313173A4 (en) * | 2021-03-31 | 2025-04-16 | MediBeacon Inc. | Purification of substituted diaminopyrazine dicarboxylic acids |
| SI4347031T1 (sl) | 2021-06-04 | 2026-01-30 | Vertex Pharmaceuticals Incorporated | N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kot modulatorji natrijevih kanalčkov |
| CN113563220B (zh) * | 2021-06-25 | 2023-08-29 | 华中农业大学 | 一种抗菌化合物及其应用 |
| CN121712741A (zh) | 2023-06-26 | 2026-03-20 | 亥姆霍兹感染研究中心有限公司 | 新型囊菌酰胺衍生物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4525354A (en) * | 1983-09-14 | 1985-06-25 | University Of Hawaii | Antibiotic and process for the production thereof |
| US7020622B1 (en) * | 1997-06-10 | 2006-03-28 | Linkshare Corporation | Transaction tracking, managing, assessment, and auditing data processing system and network |
| FR2772025B1 (fr) | 1997-12-10 | 2000-03-03 | Guerbet Sa | Chelates metalliques de macrocycles polyaminocarboxyliques et leur application a l'imagerie par resonance magnetique |
| WO2001083800A2 (en) * | 2000-04-28 | 2001-11-08 | Kosan Biosciences, Inc. | Heterologous production of polyketides |
| CA2413702A1 (en) * | 2000-06-28 | 2002-01-03 | Teva Pharmaceuticals Industries Ltd. | Carvedilol |
| US7510852B2 (en) * | 2002-10-18 | 2009-03-31 | Centre De Cooperation Internationale En Recherche Agronomique Pour Le Developpement (Cirad) | Biosynthetic genes and host cells for the synthesis of polyketide antibiotics and method of use |
| WO2006109846A1 (ja) | 2005-04-06 | 2006-10-19 | Takeda Pharmaceutical Company Limited | トリアゾール誘導体およびその用途 |
| US7758972B2 (en) * | 2006-09-26 | 2010-07-20 | Semiconductor Energy Laboratory Co., Ltd. | Stilbene derivative, light emitting element, light emitting device, and electronic appliance |
| JP5379965B2 (ja) * | 2006-09-26 | 2013-12-25 | 株式会社半導体エネルギー研究所 | スチルベン誘導体、発光素子および発光装置 |
| US7816324B2 (en) * | 2007-03-13 | 2010-10-19 | Board Of Regents, The University Of Texas System | Composition and method for the treatment of diseases affected by a peptide receptor |
| US8236983B2 (en) * | 2008-03-13 | 2012-08-07 | Board Of Regents, The University Of Texas System | Composition and method for the treatment of diseases affected by apoptosis |
| US8754124B2 (en) * | 2011-11-23 | 2014-06-17 | Board Of Regents, The University Of Texas System | Oligo-benzamide compounds and their use in treating cancers |
| EP2956437B1 (en) * | 2013-02-15 | 2023-05-10 | Technische Universität Berlin | Albicidin derivatives for the treatment of bacterial infections |
| CA2917767C (en) | 2013-07-12 | 2022-05-03 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Cystobactamides |
| US20170204052A1 (en) | 2014-05-15 | 2017-07-20 | Korea Research Institute Of Bioscience And Biotechnology | Novel antimicrobial compound and use thereof |
| CA2968270C (en) * | 2014-11-26 | 2022-11-01 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Further natural cystobactamides, synthetic derivatives thereof, and use thereof in treating bacterial infections |
-
2014
- 2014-07-14 CA CA2917767A patent/CA2917767C/en active Active
- 2014-07-14 CN CN201480050439.3A patent/CN105793424B/zh active Active
- 2014-07-14 US US14/904,654 patent/US20160145304A1/en not_active Abandoned
- 2014-07-14 AU AU2014289663A patent/AU2014289663B2/en active Active
- 2014-07-14 JP JP2016524705A patent/JP6730183B2/ja active Active
- 2014-07-14 WO PCT/EP2014/001925 patent/WO2015003816A2/en not_active Ceased
- 2014-07-14 EP EP14747296.3A patent/EP3019615B1/en active Active
-
2018
- 2018-07-23 US US16/042,753 patent/US10793600B2/en active Active
-
2020
- 2020-06-10 US US16/897,497 patent/US11225503B2/en active Active
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