AU2014289663B2 - Cystobactamides - Google Patents
Cystobactamides Download PDFInfo
- Publication number
- AU2014289663B2 AU2014289663B2 AU2014289663A AU2014289663A AU2014289663B2 AU 2014289663 B2 AU2014289663 B2 AU 2014289663B2 AU 2014289663 A AU2014289663 A AU 2014289663A AU 2014289663 A AU2014289663 A AU 2014289663A AU 2014289663 B2 AU2014289663 B2 AU 2014289663B2
- Authority
- AU
- Australia
- Prior art keywords
- group
- alkyl
- formula
- cystobactamide
- pct
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 CC(NC(C(C(O*)=O)OC)C(NC)=O)=O Chemical compound CC(NC(C(C(O*)=O)OC)C(NC)=O)=O 0.000 description 4
- XXDQFLSIIZFINO-UHFFFAOYSA-N CC(C)Oc(c(OCc1ccccc1)c(cc1)C(O)=O)c1[N+]([O-])=O Chemical compound CC(C)Oc(c(OCc1ccccc1)c(cc1)C(O)=O)c1[N+]([O-])=O XXDQFLSIIZFINO-UHFFFAOYSA-N 0.000 description 2
- SRQHPUIUCUYGOO-UHFFFAOYSA-N CC(C)NC(C(C(C(N)=O)OC)NC(C)=O)=O Chemical compound CC(C)NC(C(C(C(N)=O)OC)NC(C)=O)=O SRQHPUIUCUYGOO-UHFFFAOYSA-N 0.000 description 1
- NPMAYIZQSOBKIG-UHFFFAOYSA-N CC(C)OC(c(cc1OC(C)C)ccc1N)=O Chemical compound CC(C)OC(c(cc1OC(C)C)ccc1N)=O NPMAYIZQSOBKIG-UHFFFAOYSA-N 0.000 description 1
- JBLAKDISROPCMP-UHFFFAOYSA-N CC(C)OC(c(cc1OC(C)C)ccc1NC(c(cc1)nc(OC(C)C)c1N)=O)=O Chemical compound CC(C)OC(c(cc1OC(C)C)ccc1NC(c(cc1)nc(OC(C)C)c1N)=O)=O JBLAKDISROPCMP-UHFFFAOYSA-N 0.000 description 1
- SXMLMRAYLWLCLN-UHFFFAOYSA-N CC(C)OC(c(cc1OC(C)C)ccc1NC(c(ccc([N+]([O-])=O)c1)c1O)=O)=O Chemical compound CC(C)OC(c(cc1OC(C)C)ccc1NC(c(ccc([N+]([O-])=O)c1)c1O)=O)=O SXMLMRAYLWLCLN-UHFFFAOYSA-N 0.000 description 1
- AQIZZMSROAYWPJ-UHFFFAOYSA-N CC(C)Oc(cc(cc1)C(OC)=O)c1N Chemical compound CC(C)Oc(cc(cc1)C(OC)=O)c1N AQIZZMSROAYWPJ-UHFFFAOYSA-N 0.000 description 1
- JNRFVXKBADOXJC-UHFFFAOYSA-N CC(C)Oc(cc(cc1)C(OC)=O)c1NC(c(ccc(NC(c(cc1)ccc1N)=O)c1OC(C)C)c1O)=O Chemical compound CC(C)Oc(cc(cc1)C(OC)=O)c1NC(c(ccc(NC(c(cc1)ccc1N)=O)c1OC(C)C)c1O)=O JNRFVXKBADOXJC-UHFFFAOYSA-N 0.000 description 1
- YQMSFMKYRVLVPB-UHFFFAOYSA-N CC(C)Oc(cc(cc1)C(OC)=O)c1NC(c(ccc([N+]([O-])=O)c1OC(C)C)c1O)=O Chemical compound CC(C)Oc(cc(cc1)C(OC)=O)c1NC(c(ccc([N+]([O-])=O)c1OC(C)C)c1O)=O YQMSFMKYRVLVPB-UHFFFAOYSA-N 0.000 description 1
- DKFKAZUTHFILIQ-UHFFFAOYSA-N CC(C)Oc(nc(cc1)Cl)c1[N+]([O-])=O Chemical compound CC(C)Oc(nc(cc1)Cl)c1[N+]([O-])=O DKFKAZUTHFILIQ-UHFFFAOYSA-N 0.000 description 1
- GMZLJBDYSOMKTO-UHFFFAOYSA-N CC(C)Oc1cc(C(O)=O)ccc1NC(c(cc1)nc(OC(C)C)c1NC(c(cc1)ccc1N)=O)=O Chemical compound CC(C)Oc1cc(C(O)=O)ccc1NC(c(cc1)nc(OC(C)C)c1NC(c(cc1)ccc1N)=O)=O GMZLJBDYSOMKTO-UHFFFAOYSA-N 0.000 description 1
- QLGCYIIWWWGQAH-UHFFFAOYSA-N CC(C)Oc1cc(C(OC)=O)ccc1NC(c(ccc(C)c1OC(C)C)c1OCc1ccccc1)=O Chemical compound CC(C)Oc1cc(C(OC)=O)ccc1NC(c(ccc(C)c1OC(C)C)c1OCc1ccccc1)=O QLGCYIIWWWGQAH-UHFFFAOYSA-N 0.000 description 1
- CXALCHWVYCSUIU-UHFFFAOYSA-N CC(OC1)Oc2c1c(Br)ccc2O Chemical compound CC(OC1)Oc2c1c(Br)ccc2O CXALCHWVYCSUIU-UHFFFAOYSA-N 0.000 description 1
- XRERBLZFZMBKRU-UHFFFAOYSA-N CC(Oc(c(C=O)ccc1)c1OC)=O Chemical compound CC(Oc(c(C=O)ccc1)c1OC)=O XRERBLZFZMBKRU-UHFFFAOYSA-N 0.000 description 1
- CVKFQVDFHLSEFC-UHFFFAOYSA-N CC(Oc(c(C=O)ccc1[N+]([O-])=O)c1OC)=O Chemical compound CC(Oc(c(C=O)ccc1[N+]([O-])=O)c1OC)=O CVKFQVDFHLSEFC-UHFFFAOYSA-N 0.000 description 1
- DJLFOMMCQBAMAA-UHFFFAOYSA-N COC(c(cc1OC)ccc1N)=O Chemical compound COC(c(cc1OC)ccc1N)=O DJLFOMMCQBAMAA-UHFFFAOYSA-N 0.000 description 1
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N COc(c(O)c1C=O)ccc1Br Chemical compound COc(c(O)c1C=O)ccc1Br JUPJZUTYDWXZAQ-UHFFFAOYSA-N 0.000 description 1
- GWMPFGBRRHGDRA-UHFFFAOYSA-N COc(c([N+]([O-])=O)ccc1C(O)=O)c1O Chemical compound COc(c([N+]([O-])=O)ccc1C(O)=O)c1O GWMPFGBRRHGDRA-UHFFFAOYSA-N 0.000 description 1
- PWURRRRGLCVBMX-UHFFFAOYSA-N COc(cc(cc1)C(O)=O)c1[N+]([O-])=O Chemical compound COc(cc(cc1)C(O)=O)c1[N+]([O-])=O PWURRRRGLCVBMX-UHFFFAOYSA-N 0.000 description 1
- JJVNINGBHGBWJH-UHFFFAOYSA-N COc(cccc1C=O)c1O Chemical compound COc(cccc1C=O)c1O JJVNINGBHGBWJH-UHFFFAOYSA-N 0.000 description 1
- CRTWONPTSVRAFC-UHFFFAOYSA-N COc1cc(C(O)=O)ccc1NC(c(c(O)c1OC)ccc1[N+]([O-])=O)=O Chemical compound COc1cc(C(O)=O)ccc1NC(c(c(O)c1OC)ccc1[N+]([O-])=O)=O CRTWONPTSVRAFC-UHFFFAOYSA-N 0.000 description 1
- SHCWQWRTKPNTEM-UHFFFAOYSA-N [O-][N+](c(ccc(Cl)n1)c1Cl)=O Chemical compound [O-][N+](c(ccc(Cl)n1)c1Cl)=O SHCWQWRTKPNTEM-UHFFFAOYSA-N 0.000 description 1
- UKWUOTZGXIZAJC-UHFFFAOYSA-N [O-][N+](c1ccc(C(O)=O)c(O)c1)=O Chemical compound [O-][N+](c1ccc(C(O)=O)c(O)c1)=O UKWUOTZGXIZAJC-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyridine Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13003539 | 2013-07-12 | ||
| EP13003539.7 | 2013-07-12 | ||
| PCT/EP2014/001925 WO2015003816A2 (en) | 2013-07-12 | 2014-07-14 | Cystobactamides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2014289663A1 AU2014289663A1 (en) | 2016-02-04 |
| AU2014289663B2 true AU2014289663B2 (en) | 2019-03-07 |
Family
ID=48792948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014289663A Active AU2014289663B2 (en) | 2013-07-12 | 2014-07-14 | Cystobactamides |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20160145304A1 (enExample) |
| EP (1) | EP3019615B1 (enExample) |
| JP (1) | JP6730183B2 (enExample) |
| CN (1) | CN105793424B (enExample) |
| AU (1) | AU2014289663B2 (enExample) |
| CA (1) | CA2917767C (enExample) |
| WO (1) | WO2015003816A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2917767C (en) | 2013-07-12 | 2022-05-03 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Cystobactamides |
| GB201402277D0 (en) | 2014-02-10 | 2014-03-26 | Sentinel Oncology Ltd | Pharmaceutical compounds |
| US20170204052A1 (en) * | 2014-05-15 | 2017-07-20 | Korea Research Institute Of Bioscience And Biotechnology | Novel antimicrobial compound and use thereof |
| CA2968270C (en) * | 2014-11-26 | 2022-11-01 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Further natural cystobactamides, synthetic derivatives thereof, and use thereof in treating bacterial infections |
| CN105712894A (zh) * | 2016-03-23 | 2016-06-29 | 叶芳 | 一种3-甲氧基-4-氨基苯甲酸及其制备方法 |
| WO2018062422A1 (ja) * | 2016-09-28 | 2018-04-05 | 日産化学工業株式会社 | ジアミンおよびその利用 |
| BR102018007822A2 (pt) | 2017-04-20 | 2018-11-06 | Gilead Sciences, Inc. | composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição |
| AU2018300150A1 (en) | 2017-07-11 | 2020-01-30 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| EP3655394B1 (en) * | 2017-07-18 | 2023-11-22 | Technische Universität Berlin | Novel albicidin derivatives, their use and synthesis |
| US11034648B2 (en) * | 2017-08-23 | 2021-06-15 | Helmholtz-Zentrum Für | Cystobactamide derivatives |
| AU2018346597B2 (en) | 2017-10-06 | 2023-07-13 | Forma Therapeutics, Inc. | Inhibiting Ubiquitin Specific Peptidase 30 |
| IL316472A (en) | 2018-01-10 | 2024-12-01 | Recurium Ip Holdings Llc | Benzamide compounds |
| WO2019160882A1 (en) | 2018-02-13 | 2019-08-22 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
| KR102591947B1 (ko) | 2018-04-19 | 2023-10-25 | 길리애드 사이언시즈, 인코포레이티드 | Pd-1/pd-l1 억제제 |
| IL278291B2 (en) | 2018-05-17 | 2023-10-01 | Forma Therapeutics Inc | Condensed bicyclic compounds are useful as ubiquitin-specific peptidase 30 inhibitors |
| PE20210642A1 (es) | 2018-07-13 | 2021-03-23 | Gilead Sciences Inc | Inhibidores de pd-1/pd-l1 |
| EP4218934B1 (en) | 2018-10-05 | 2025-06-18 | Forma Therapeutics, Inc. | Inhibiting ubiquitin-specific protease 30 (usp30) |
| US11236085B2 (en) | 2018-10-24 | 2022-02-01 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
| WO2020146682A1 (en) | 2019-01-10 | 2020-07-16 | Vertex Pharmaceuticals Incorporated | Carboxamides as modulators of sodium channels |
| WO2020146612A1 (en) | 2019-01-10 | 2020-07-16 | Vertex Pharmaceuticals Incorporated | Esters and carbamates as modulators of sodium channels |
| AU2020300619A1 (en) | 2019-07-03 | 2022-01-27 | Sumitomo Pharma Oncology, Inc. | Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof |
| PH12022551379A1 (en) | 2019-12-06 | 2023-05-03 | Vertex Pharma | Substituted tetrahydrofurans as modulators of sodium channels |
| EP4313173A4 (en) * | 2021-03-31 | 2025-04-16 | MediBeacon Inc. | Purification of substituted diaminopyrazine dicarboxylic acids |
| SI4347031T1 (sl) | 2021-06-04 | 2026-01-30 | Vertex Pharmaceuticals Incorporated | N-(hidroksialkil (hetero)aril) tetrahidrofuran karboksamidi kot modulatorji natrijevih kanalčkov |
| CN113563220B (zh) * | 2021-06-25 | 2023-08-29 | 华中农业大学 | 一种抗菌化合物及其应用 |
| CN121712741A (zh) | 2023-06-26 | 2026-03-20 | 亥姆霍兹感染研究中心有限公司 | 新型囊菌酰胺衍生物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4525354A (en) * | 1983-09-14 | 1985-06-25 | University Of Hawaii | Antibiotic and process for the production thereof |
| US7020622B1 (en) * | 1997-06-10 | 2006-03-28 | Linkshare Corporation | Transaction tracking, managing, assessment, and auditing data processing system and network |
| FR2772025B1 (fr) | 1997-12-10 | 2000-03-03 | Guerbet Sa | Chelates metalliques de macrocycles polyaminocarboxyliques et leur application a l'imagerie par resonance magnetique |
| WO2001083800A2 (en) * | 2000-04-28 | 2001-11-08 | Kosan Biosciences, Inc. | Heterologous production of polyketides |
| CA2413702A1 (en) * | 2000-06-28 | 2002-01-03 | Teva Pharmaceuticals Industries Ltd. | Carvedilol |
| US7510852B2 (en) * | 2002-10-18 | 2009-03-31 | Centre De Cooperation Internationale En Recherche Agronomique Pour Le Developpement (Cirad) | Biosynthetic genes and host cells for the synthesis of polyketide antibiotics and method of use |
| WO2006109846A1 (ja) | 2005-04-06 | 2006-10-19 | Takeda Pharmaceutical Company Limited | トリアゾール誘導体およびその用途 |
| US7758972B2 (en) * | 2006-09-26 | 2010-07-20 | Semiconductor Energy Laboratory Co., Ltd. | Stilbene derivative, light emitting element, light emitting device, and electronic appliance |
| JP5379965B2 (ja) * | 2006-09-26 | 2013-12-25 | 株式会社半導体エネルギー研究所 | スチルベン誘導体、発光素子および発光装置 |
| US7816324B2 (en) * | 2007-03-13 | 2010-10-19 | Board Of Regents, The University Of Texas System | Composition and method for the treatment of diseases affected by a peptide receptor |
| US8236983B2 (en) * | 2008-03-13 | 2012-08-07 | Board Of Regents, The University Of Texas System | Composition and method for the treatment of diseases affected by apoptosis |
| US8754124B2 (en) * | 2011-11-23 | 2014-06-17 | Board Of Regents, The University Of Texas System | Oligo-benzamide compounds and their use in treating cancers |
| EP2956437B1 (en) * | 2013-02-15 | 2023-05-10 | Technische Universität Berlin | Albicidin derivatives for the treatment of bacterial infections |
| CA2917767C (en) | 2013-07-12 | 2022-05-03 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Cystobactamides |
| US20170204052A1 (en) | 2014-05-15 | 2017-07-20 | Korea Research Institute Of Bioscience And Biotechnology | Novel antimicrobial compound and use thereof |
| CA2968270C (en) * | 2014-11-26 | 2022-11-01 | Helmholtz-Zentrum Fur Infektionsforschung Gmbh | Further natural cystobactamides, synthetic derivatives thereof, and use thereof in treating bacterial infections |
-
2014
- 2014-07-14 CA CA2917767A patent/CA2917767C/en active Active
- 2014-07-14 CN CN201480050439.3A patent/CN105793424B/zh active Active
- 2014-07-14 US US14/904,654 patent/US20160145304A1/en not_active Abandoned
- 2014-07-14 AU AU2014289663A patent/AU2014289663B2/en active Active
- 2014-07-14 JP JP2016524705A patent/JP6730183B2/ja active Active
- 2014-07-14 WO PCT/EP2014/001925 patent/WO2015003816A2/en not_active Ceased
- 2014-07-14 EP EP14747296.3A patent/EP3019615B1/en active Active
-
2018
- 2018-07-23 US US16/042,753 patent/US10793600B2/en active Active
-
2020
- 2020-06-10 US US16/897,497 patent/US11225503B2/en active Active
Non-Patent Citations (1)
| Title |
|---|
| ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2011, vol. 55, no. 11, pages 5043 - 5053 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2917767A1 (en) | 2015-01-15 |
| US20160145304A1 (en) | 2016-05-26 |
| CN105793424A (zh) | 2016-07-20 |
| WO2015003816A2 (en) | 2015-01-15 |
| US20190185514A1 (en) | 2019-06-20 |
| EP3019615B1 (en) | 2021-04-07 |
| CN105793424B (zh) | 2021-02-19 |
| US11225503B2 (en) | 2022-01-18 |
| US10793600B2 (en) | 2020-10-06 |
| JP6730183B2 (ja) | 2020-07-29 |
| CA2917767C (en) | 2022-05-03 |
| US20200331964A1 (en) | 2020-10-22 |
| EP3019615A2 (en) | 2016-05-18 |
| AU2014289663A1 (en) | 2016-02-04 |
| JP2016527215A (ja) | 2016-09-08 |
| WO2015003816A3 (en) | 2015-03-12 |
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