|
HU168036B
(OSRAM)
|
1973-11-09 |
1976-02-28 |
|
|
|
HU168776B
(OSRAM)
|
1973-11-09 |
1976-07-28 |
|
|
|
CA1098910A
(en)
|
1978-06-15 |
1981-04-07 |
Robert N. Schut |
3-amino-2-(5-fluoro and 5-methoxy-1h-indol-3-yl) propanoic acid derivatives
|
|
JPS57116067A
(en)
|
1981-01-12 |
1982-07-19 |
Sankyo Kagaku Kk |
Novel 8-quinolinesulfonyl derivative, its synthesis and use
|
|
DE3703435A1
(de)
|
1987-02-05 |
1988-08-18 |
Thomae Gmbh Dr K |
Neue thiazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
IE68593B1
(en)
|
1989-12-06 |
1996-06-26 |
Sanofi Sa |
Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
|
|
US5945380A
(en)
|
1995-05-26 |
1999-08-31 |
Bayer Aktiengesellschaft |
Pyridyl-thiazoles and their use to protect plants against infections by micro-organisms
|
|
US6187797B1
(en)
|
1996-12-23 |
2001-02-13 |
Dupont Pharmaceuticals Company |
Phenyl-isoxazoles as factor XA Inhibitors
|
|
WO1998028282A2
(en)
|
1996-12-23 |
1998-07-02 |
Du Pont Pharmaceuticals Company |
OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS
|
|
CA2302417A1
(en)
|
1997-10-27 |
1999-05-06 |
Takeda Chemical Industries, Ltd. |
Adenosine a3 receptor antagonists
|
|
WO1999052906A1
(de)
|
1998-04-08 |
1999-10-21 |
Bayer Aktiengesellschaft |
Substituierte oxazolyl- und thiazolyl-uracil herbizide
|
|
WO2001007423A1
(en)
|
1999-07-26 |
2001-02-01 |
Shionogi & Co., Ltd. |
Drug compositions exhibiting thrombopoietin agonism
|
|
ATE465161T1
(de)
*
|
2000-03-15 |
2010-05-15 |
Sanofi Aventis Deutschland |
Substituierte beta-carboline mit ikb-kinase hemmender wirkung
|
|
EP1268477B1
(en)
|
2000-03-15 |
2010-04-21 |
Sanofi-Aventis Deutschland GmbH |
Substituted beta-carbolines with ikb-kinase inhibiting activity
|
|
GB0010183D0
(en)
|
2000-04-26 |
2000-06-14 |
Ferring Bv |
Inhibitors of dipeptidyl peptidase IV
|
|
EP1310494B1
(en)
|
2000-08-11 |
2012-01-25 |
Nippon Chemiphar Co., Ltd. |
PPAR (delta) ACTIVATORS
|
|
JP2002053566A
(ja)
|
2000-08-11 |
2002-02-19 |
Japan Tobacco Inc |
チアゾール化合物及びその医薬用途
|
|
US20020173507A1
(en)
|
2000-08-15 |
2002-11-21 |
Vincent Santora |
Urea compounds and methods of uses
|
|
US20020103192A1
(en)
|
2000-10-26 |
2002-08-01 |
Curtin Michael L. |
Inhibitors of histone deacetylase
|
|
EP1354603A1
(en)
|
2000-12-26 |
2003-10-22 |
Takeda Chemical Industries, Ltd. |
Concomitant drugs
|
|
WO2002062775A1
(en)
|
2001-02-02 |
2002-08-15 |
Yamanouchi Pharmaceutical Co., Ltd. |
2-acylaminothiazole derivative or its salt
|
|
MY130778A
(en)
|
2001-02-09 |
2007-07-31 |
Vertex Pharma |
Heterocyclic inhibitiors of erk2 and uses thereof
|
|
US20020177594A1
(en)
|
2001-03-14 |
2002-11-28 |
Curtin Michael L. |
Inhibitors of histone deacetylase
|
|
EP1371650A4
(en)
|
2001-03-23 |
2005-05-04 |
Nippon Chemiphar Co |
ACTIVATED RECEPTOR ACTIVATOR BY PEROXYSOME PROLIFIERS
|
|
US20050009843A1
(en)
|
2001-04-26 |
2005-01-13 |
Kiyoshi Nakayama |
Medicine for inhibiting drug elimination pump
|
|
US20050080113A1
(en)
|
2001-06-11 |
2005-04-14 |
Shigenori Ohkawa |
Medicinal compositions
|
|
GB0123589D0
(en)
|
2001-10-01 |
2001-11-21 |
Syngenta Participations Ag |
Organic compounds
|
|
CA2469228A1
(en)
|
2001-12-03 |
2003-06-12 |
Japan Tobacco Inc. |
Azole compound and medicinal use thereof
|
|
EP2314586B1
(en)
|
2002-01-18 |
2016-09-14 |
Astellas Pharma Inc. |
2-Acylaminothiazole derivative or salt thereof
|
|
CA2474322A1
(en)
|
2002-01-25 |
2003-07-31 |
Kylix Pharmaceuticals B.V. |
4(hetero-) aryl substituted (thia-/oxa-/pyra) zoles for inhibition of tie-2
|
|
US7229987B2
(en)
|
2002-05-13 |
2007-06-12 |
Eli Lilly And Company |
Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes
|
|
EP1534273A4
(en)
|
2002-07-18 |
2007-08-22 |
Bristol Myers Squibb Co |
MODULATORS OF THE GLUCOCORTICOID RECEPTOR AND METHOD
|
|
US20040132726A1
(en)
|
2002-08-09 |
2004-07-08 |
Astrazeneca Ab And Nps Pharmaceuticals, Inc. |
New compounds
|
|
WO2004016592A1
(en)
|
2002-08-14 |
2004-02-26 |
Ppd Discovery, Inc. |
Prenylation inhibitors and methods of their synthesis and use
|
|
CA2504320A1
(en)
|
2002-10-30 |
2004-05-21 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of rock and other protein kinases
|
|
GB0230087D0
(en)
|
2002-12-24 |
2003-01-29 |
Astrazeneca Ab |
Therapeutic agents
|
|
GB0302672D0
(en)
|
2003-02-06 |
2003-03-12 |
Astrazeneca Ab |
Pharmaceutical formulations
|
|
WO2004071509A1
(ja)
|
2003-02-12 |
2004-08-26 |
Nippon Chemiphar Co., Ltd. |
オリゴデンドロサイト分化促進剤
|
|
WO2004092115A2
(en)
|
2003-04-07 |
2004-10-28 |
Axys Pharmaceuticals Inc. |
Hydroxamates as therapeutic agents
|
|
WO2004094375A2
(en)
|
2003-04-16 |
2004-11-04 |
Memory Pharmaceuticals Corporation |
4 - (3,4 - disubstituted phenyl) - pyrrolidin-2-one compounds as phosphodiesterase 4 inhibitors
|
|
CN100545161C
(zh)
|
2003-08-15 |
2009-09-30 |
中国科学院上海药物研究所 |
一类杂环衍生物、制备方法及其用途
|
|
US7351727B2
(en)
|
2003-09-02 |
2008-04-01 |
Bristol-Myers Squibb Company |
Inhibitors of 15-lipoxygenase
|
|
CN1898221A
(zh)
|
2003-09-06 |
2007-01-17 |
沃泰克斯药物股份有限公司 |
Atp－结合弹夹转运蛋白的调控剂
|
|
AR045651A1
(es)
|
2003-09-19 |
2005-11-02 |
Solvay Pharm Bv |
Derivados de tiazol como moduladores del receptor de cannabinoide
|
|
WO2005044194A2
(en)
|
2003-10-28 |
2005-05-19 |
Pharmacia Corporation |
TREATMENT OR PREVENTION OF NEOPLASIA BY USE OF AN Hsp90 INHIBITOR
|
|
WO2005041879A2
(en)
|
2003-10-28 |
2005-05-12 |
Pharmacia Corporation |
COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA
|
|
JP2007519754A
(ja)
|
2004-01-30 |
2007-07-19 |
スミスクライン ビーチャム コーポレーション |
化合物
|
|
EP1716122B1
(en)
|
2004-01-30 |
2017-04-19 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters
|
|
WO2005077345A1
(en)
|
2004-02-03 |
2005-08-25 |
Astrazeneca Ab |
Compounds for the treatment of gastro-esophageal reflux disease
|
|
WO2005077373A2
(en)
|
2004-02-03 |
2005-08-25 |
Astrazeneca Ab |
Treatment of gastro-esophageal reflux disease (gerd)
|
|
WO2005077900A1
(ja)
|
2004-02-18 |
2005-08-25 |
Kyorin Pharmaceutical Co., Ltd. |
ビシクロアミド誘導体
|
|
MY148488A
(en)
|
2004-02-18 |
2013-04-30 |
Astrazeneca Ab |
Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
|
|
US7259155B2
(en)
|
2004-05-05 |
2007-08-21 |
Otsuka Pharmaceutical Factory, Inc. |
Phosphonic diester derivatives
|
|
WO2006104141A1
(ja)
|
2005-03-29 |
2006-10-05 |
Shionogi & Co., Ltd. |
３－プロペニルセフェム誘導体
|
|
FR2885129B1
(fr)
|
2005-04-29 |
2007-06-15 |
Proskelia Sas |
Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
|
|
WO2006122011A2
(en)
|
2005-05-09 |
2006-11-16 |
Achillion Pharmaceuticals, Inc. |
Thiazole compounds and methods of use
|
|
US7655446B2
(en)
|
2005-06-28 |
2010-02-02 |
Vertex Pharmaceuticals Incorporated |
Crystal structure of Rho-kinase I kinase domain complexes and binding pockets thereof
|
|
US20100168102A9
(en)
*
|
2005-07-11 |
2010-07-01 |
Devgen Nv |
Amide Derivatives as Kinase Inhibitors
|
|
CA2630920A1
(en)
|
2005-11-22 |
2007-05-31 |
University Of South Florida |
Inhibition of cell proliferation
|
|
WO2007075896A2
(en)
|
2005-12-22 |
2007-07-05 |
Kemia, Inc. |
Heterocyclic cytokine inhibitors
|
|
WO2007087427A2
(en)
|
2006-01-25 |
2007-08-02 |
Synta Pharmaceuticals Corp. |
Thiazole and thiadiazole compounds for inflammation and immune-related uses
|
|
WO2007116106A1
(es)
|
2006-04-12 |
2007-10-18 |
Palobiofarma, S.L. |
Nuevos compuestos como antagonistas de los receptores a1 de adenosina
|
|
AU2007249891A1
(en)
|
2006-05-12 |
2007-11-22 |
Vertex Pharmaceuticals Incorporated |
Selective inhibitors of ROCK protein kinase and uses thereof
|
|
JP5448164B2
(ja)
|
2006-07-28 |
2014-03-19 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｃｂ２受容体を変調する化合物
|
|
US7928123B2
(en)
|
2006-09-25 |
2011-04-19 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the CB2 receptor
|
|
TW200831081A
(en)
|
2006-12-25 |
2008-08-01 |
Kyorin Seiyaku Kk |
Glucokinase activator
|
|
WO2008124000A2
(en)
|
2007-04-02 |
2008-10-16 |
Ligand Pharmaceuticals Incorporated |
Thiazole derivatives as androgen receptor modulator compounds
|
|
GB0706793D0
(en)
|
2007-04-05 |
2007-05-16 |
Evotec Ag |
Compounds
|
|
SI3184527T1
(sl)
|
2007-06-22 |
2020-03-31 |
Eli Lilly And Company |
Spojine 2,6-diokso,-2,3-dihidro-1H-purina uporabne za zdravljenje stanj povezanih z aktivnostjo TRPA1 kanala
|
|
EP2193119B1
(en)
|
2007-08-27 |
2014-01-01 |
Abbvie Deutschland GmbH & Co. KG |
4-(4-pyridinyl)-benzamides and their use as rock activity modulators
|
|
TW200916447A
(en)
|
2007-08-29 |
2009-04-16 |
Methylgene Inc |
Sirtuin inhibitors
|
|
ES2331220B1
(es)
|
2007-10-02 |
2010-09-23 |
Palobiofarma, S.L. |
Nuevos compuestos como antagonistas de los receptores a1 de adenosina.
|
|
US8440666B2
(en)
|
2007-10-31 |
2013-05-14 |
Nissan Chemical Industries, Ltd. |
Pyridazinone compounds and P2X7 receptor inhibitors
|
|
EP2217565B1
(en)
|
2007-11-07 |
2013-05-22 |
Boehringer Ingelheim International GmbH |
Compounds which modulate the cb2 receptor
|
|
WO2009067607A2
(en)
|
2007-11-20 |
2009-05-28 |
Memory Pharmaceuticals Corporation |
Combinations of pde4 inhibitors and antipsychotics for the treatment of psychotic disorders
|
|
WO2009081222A1
(en)
|
2007-12-21 |
2009-07-02 |
Glenmark Pharmaceuticals, S.A. |
Substituted tricyclic pyridine or pyrimidine vanilloid receptor ligands
|
|
US8642660B2
(en)
|
2007-12-21 |
2014-02-04 |
The University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
EP3067038B1
(en)
|
2008-02-08 |
2017-10-11 |
Shiseido Company, Ltd. |
Skin whitening agent
|
|
WO2009114552A1
(en)
|
2008-03-10 |
2009-09-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Heteroaryl compounds, compositions, and methods of use in cancer treatment
|
|
WO2009140519A1
(en)
|
2008-05-14 |
2009-11-19 |
Hydra Biosciences, Inc. |
Compounds and compositions for treating chemical warfare agent-induced injuries
|
|
WO2010028193A1
(en)
|
2008-09-03 |
2010-03-11 |
Repligen Corporation |
Compounds including pimelic acid derivatives as hdac inhibitors
|
|
US20100063085A1
(en)
*
|
2008-09-11 |
2010-03-11 |
University Court Of The University Of Dundee |
Method of treating learning impairment in down's syndrome subjects
|
|
WO2010029300A1
(en)
|
2008-09-12 |
2010-03-18 |
Biolipox Ab |
Bis aromatic compounds for use in the treatment of inflammation
|
|
WO2010036821A1
(en)
|
2008-09-24 |
2010-04-01 |
Hydra Biosciences, Inc. |
Methods and compositions for treating respiratory disorders
|
|
BRPI0923009B1
(pt)
|
2008-12-19 |
2018-07-17 |
Elanco Tiergesundheit Ag |
compostos de isoxazolina, composição para o controle de parasitas e uso de compostos de isoxazolina para o preparo de composição para o controle de parasitas
|
|
US8815840B2
(en)
*
|
2008-12-19 |
2014-08-26 |
Bristol-Myers Squibb Company |
Carbazole and carboline kinase inhibitors
|
|
ES2567047T3
(es)
|
2008-12-23 |
2016-04-19 |
Abbvie Inc. |
Derivados de pirimidina anti-virales
|
|
JP2012051804A
(ja)
*
|
2008-12-26 |
2012-03-15 |
Kyoto Univ |
Ｅｇ５阻害剤
|
|
UA103918C2
(en)
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
|
|
US8362249B2
(en)
|
2009-04-27 |
2013-01-29 |
Boehringer Ingelheim International Gmbh |
CXCR3 receptor antagonists
|
|
EP2440054A4
(en)
|
2009-06-09 |
2012-12-12 |
California Capital Equity Llc |
PYRIDILTRIA INHIBITOR OF HEDGEHOG SIGNALING
|
|
DK2470173T3
(en)
|
2009-08-25 |
2016-06-06 |
Abraxis Bioscience Llc |
Combination therapy of nanoparticle composition of the taxane and the hedgehog inhibitors
|
|
AU2010322287B2
(en)
*
|
2009-11-17 |
2014-04-03 |
The Regents Of The University Of Michigan |
1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
|
|
WO2011075684A1
(en)
|
2009-12-18 |
2011-06-23 |
Activesite Pharmaceuticals, Inc. |
Prodrugs of inhibitors of plasma kallikrein
|
|
JP5766690B2
(ja)
|
2010-04-12 |
2015-08-19 |
塩野義製薬株式会社 |
インテグラーゼ阻害活性を有するピリドン誘導体
|
|
US9221808B2
(en)
|
2010-04-16 |
2015-12-29 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinase (ROCK) and methods of use
|
|
US8685969B2
(en)
*
|
2010-06-16 |
2014-04-01 |
Bristol-Myers Squibb Company |
Carboline carboxamide compounds useful as kinase inhibitors
|
|
JP5769326B2
(ja)
|
2010-10-19 |
2015-08-26 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｒｈｏキナーゼ阻害薬
|
|
US8703953B2
(en)
|
2012-03-09 |
2014-04-22 |
Bristol-Myers Squibb Company |
Aryl ether-base kinase inhibitors
|
|
HK1199814A1
(en)
*
|
2012-03-09 |
2015-07-24 |
Lexicon Pharmaceuticals, Inc. |
Inhibition of adaptor associated kinase 1 for the treatment of pain
|
|
JP6434968B2
(ja)
|
2013-07-02 |
2018-12-05 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
Ｒｏｃｋ阻害剤としての三環式ピリド−カルボキサミド誘導体
|
|
CN105518005B
(zh)
|
2013-07-02 |
2018-07-20 |
百时美施贵宝公司 |
作为rock抑制剂的三环吡啶-甲酰胺衍生物
|