JP2016520114A - 除痛および麻酔の提供のためのジヒドロエトルフィン - Google Patents

除痛および麻酔の提供のためのジヒドロエトルフィン Download PDF

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Publication number
JP2016520114A
JP2016520114A JP2016516232A JP2016516232A JP2016520114A JP 2016520114 A JP2016520114 A JP 2016520114A JP 2016516232 A JP2016516232 A JP 2016516232A JP 2016516232 A JP2016516232 A JP 2016516232A JP 2016520114 A JP2016520114 A JP 2016520114A
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JP
Japan
Prior art keywords
level
dihydroetorphine
dihydroethorphine
dose
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016516232A
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English (en)
Japanese (ja)
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JP2016520114A5 (enExample
Inventor
ワトキンス デビッド
ワトキンス デビッド
オクシェ アレクサンダー
オクシェ アレクサンダー
スミス ケヴィン
スミス ケヴィン
マンシッカ ヘイッキ
マンシッカ ヘイッキ
ベイリー ポール
ベイリー ポール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euroceltique SA
Euro Celtique SA
Original Assignee
Euroceltique SA
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euroceltique SA, Euro Celtique SA filed Critical Euroceltique SA
Publication of JP2016520114A publication Critical patent/JP2016520114A/ja
Publication of JP2016520114A5 publication Critical patent/JP2016520114A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
    • C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
    • C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
JP2016516232A 2013-05-30 2014-05-30 除痛および麻酔の提供のためのジヒドロエトルフィン Pending JP2016520114A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1309654.0 2013-05-30
GBGB1309654.0A GB201309654D0 (en) 2013-05-30 2013-05-30 Method
PCT/GB2014/000206 WO2014191710A1 (en) 2013-05-30 2014-05-30 Dihydroetorphine for the provision of pain relief and anaesthesia

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019051613A Division JP2019123730A (ja) 2013-05-30 2019-03-19 除痛および麻酔の提供のためのジヒドロエトルフィン

Publications (2)

Publication Number Publication Date
JP2016520114A true JP2016520114A (ja) 2016-07-11
JP2016520114A5 JP2016520114A5 (enExample) 2017-07-13

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016516232A Pending JP2016520114A (ja) 2013-05-30 2014-05-30 除痛および麻酔の提供のためのジヒドロエトルフィン
JP2019051613A Pending JP2019123730A (ja) 2013-05-30 2019-03-19 除痛および麻酔の提供のためのジヒドロエトルフィン
JP2020156242A Pending JP2020200345A (ja) 2013-05-30 2020-09-17 除痛および麻酔の提供のためのジヒドロエトルフィン

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2019051613A Pending JP2019123730A (ja) 2013-05-30 2019-03-19 除痛および麻酔の提供のためのジヒドロエトルフィン
JP2020156242A Pending JP2020200345A (ja) 2013-05-30 2020-09-17 除痛および麻酔の提供のためのジヒドロエトルフィン

Country Status (13)

Country Link
US (2) US10898479B2 (enExample)
EP (1) EP3003310A1 (enExample)
JP (3) JP2016520114A (enExample)
KR (1) KR20160013977A (enExample)
CN (1) CN105555274A (enExample)
AU (1) AU2014272924B2 (enExample)
BR (1) BR112015029709A2 (enExample)
CA (1) CA2913849A1 (enExample)
GB (1) GB201309654D0 (enExample)
HK (1) HK1222585A1 (enExample)
MX (1) MX2015016418A (enExample)
PH (1) PH12015502655A1 (enExample)
WO (1) WO2014191710A1 (enExample)

Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
SI3287123T1 (sl) 2011-03-04 2020-07-31 Gruenenthal Gmbh Vodna farmacevtska formulacija tapentadola za peroralno uporabo
PT3479823T (pt) 2015-03-27 2020-09-29 Gruenenthal Gmbh Formulação estável para administração parentérica de tapentadol
GB201513442D0 (en) * 2015-07-30 2015-09-16 Euro Celtique Sa Transdermal patch
EP3515412B1 (en) 2016-09-23 2025-04-23 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
WO2018153947A1 (en) 2017-02-23 2018-08-30 Grünenthal GmbH Tapentadol as local anesthetic

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Also Published As

Publication number Publication date
CA2913849A1 (en) 2014-12-04
EP3003310A1 (en) 2016-04-13
PH12015502655A1 (en) 2016-03-07
GB201309654D0 (en) 2013-07-17
AU2014272924A1 (en) 2016-01-28
AU2014272924B2 (en) 2019-05-02
JP2020200345A (ja) 2020-12-17
WO2014191710A1 (en) 2014-12-04
HK1222585A1 (zh) 2017-07-07
US10898479B2 (en) 2021-01-26
BR112015029709A2 (pt) 2017-07-25
KR20160013977A (ko) 2016-02-05
US20210085673A1 (en) 2021-03-25
US20160106736A1 (en) 2016-04-21
JP2019123730A (ja) 2019-07-25
CN105555274A (zh) 2016-05-04
MX2015016418A (es) 2016-11-08

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