JP2016519932A5 - - Google Patents
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- JP2016519932A5 JP2016519932A5 JP2016513127A JP2016513127A JP2016519932A5 JP 2016519932 A5 JP2016519932 A5 JP 2016519932A5 JP 2016513127 A JP2016513127 A JP 2016513127A JP 2016513127 A JP2016513127 A JP 2016513127A JP 2016519932 A5 JP2016519932 A5 JP 2016519932A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- human
- sortase
- antibody
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000005260 human cell Anatomy 0.000 claims 21
- 210000004027 cell Anatomy 0.000 claims 12
- 239000003814 drug Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 229940124597 therapeutic agent Drugs 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 229920001184 polypeptide Polymers 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 210000003743 erythrocyte Anatomy 0.000 claims 3
- 210000000987 immune system Anatomy 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 239000000758 substrate Substances 0.000 claims 3
- 108010003723 Single-Domain Antibodies Proteins 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 239000003054 catalyst Substances 0.000 claims 2
- 239000002738 chelating agent Substances 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000002872 contrast media Substances 0.000 claims 2
- 239000003431 cross linking reagent Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 239000002243 precursor Substances 0.000 claims 2
- 150000003384 small molecules Chemical class 0.000 claims 2
- 239000003053 toxin Substances 0.000 claims 2
- 231100000765 toxin Toxicity 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 230000000269 nucleophilic effect Effects 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019079111A JP6901154B2 (ja) | 2013-05-10 | 2019-04-18 | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361822092P | 2013-05-10 | 2013-05-10 | |
| US61/822,092 | 2013-05-10 | ||
| US201461943094P | 2014-02-21 | 2014-02-21 | |
| US61/943,094 | 2014-02-21 | ||
| PCT/US2014/037545 WO2014183066A2 (en) | 2013-05-10 | 2014-05-09 | Protein modification of living cells using sortase |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019079111A Division JP6901154B2 (ja) | 2013-05-10 | 2019-04-18 | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016519932A JP2016519932A (ja) | 2016-07-11 |
| JP2016519932A5 true JP2016519932A5 (cg-RX-API-DMAC7.html) | 2017-06-22 |
| JP6603209B2 JP6603209B2 (ja) | 2019-11-06 |
Family
ID=51867884
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016513127A Expired - Fee Related JP6603209B2 (ja) | 2013-05-10 | 2014-05-09 | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
| JP2019079111A Expired - Fee Related JP6901154B2 (ja) | 2013-05-10 | 2019-04-18 | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
| JP2021043795A Active JP7306731B2 (ja) | 2013-05-10 | 2021-03-17 | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019079111A Expired - Fee Related JP6901154B2 (ja) | 2013-05-10 | 2019-04-18 | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
| JP2021043795A Active JP7306731B2 (ja) | 2013-05-10 | 2021-03-17 | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US10260038B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2994530A4 (cg-RX-API-DMAC7.html) |
| JP (3) | JP6603209B2 (cg-RX-API-DMAC7.html) |
| AU (3) | AU2014262469B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2014183066A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (113)
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| JP6603209B2 (ja) | 2013-05-10 | 2019-11-06 | ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ | ソルターゼ（Ｓｏｒｔａｓｅ）を用いた生存細胞のタンパク質修飾 |
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- 2014-05-09 EP EP14795120.6A patent/EP2994530A4/en not_active Withdrawn
- 2014-05-09 EP EP22173120.1A patent/EP4119662A1/en not_active Withdrawn
- 2014-05-09 AU AU2014262469A patent/AU2014262469B2/en not_active Expired - Fee Related
- 2014-05-09 US US14/890,296 patent/US10260038B2/en active Active
- 2014-05-09 WO PCT/US2014/037545 patent/WO2014183066A2/en not_active Ceased
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2019
- 2019-02-15 US US16/277,721 patent/US12331311B2/en active Active
- 2019-04-11 US US16/381,654 patent/US11492590B2/en active Active
- 2019-04-18 JP JP2019079111A patent/JP6901154B2/ja not_active Expired - Fee Related
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- 2021-03-17 JP JP2021043795A patent/JP7306731B2/ja active Active
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- 2022-09-14 AU AU2022231702A patent/AU2022231702A1/en not_active Abandoned
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