JP2012523221A5 - - Google Patents

Info

Publication number

JP2012523221A5

JP2012523221A5 JP2012503917A JP2012503917A JP2012523221A5 JP 2012523221 A5 JP2012523221 A5 JP 2012523221A5 JP 2012503917 A JP2012503917 A JP 2012503917A JP 2012503917 A JP2012503917 A JP 2012503917A JP 2012523221 A5 JP2012523221 A5 JP 2012523221A5

Authority

JP

Japan

Prior art keywords

human monoclonal

monoclonal antibody

human

seq

light chain

Prior art date

2010-04-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 102000039446 nucleic acids Human genes 0.000 claims 10
• 108020004707 nucleic acids Proteins 0.000 claims 10
• 150000007523 nucleic acids Chemical class 0.000 claims 10
• 125000003275 alpha amino acid group Chemical group 0.000 claims 5
• 239000002158 endotoxin Substances 0.000 claims 5
• 229920006008 lipopolysaccharide Polymers 0.000 claims 5
• 210000004027 cell Anatomy 0.000 claims 4
• 208000032536 Pseudomonas Infections Diseases 0.000 claims 3
• 210000004408 hybridoma Anatomy 0.000 claims 3
• 210000003719 b-lymphocyte Anatomy 0.000 claims 2
• 238000012258 culturing Methods 0.000 claims 2
• 230000002265 prevention Effects 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 206010011409 Cross infection Diseases 0.000 claims 1
• 102000008300 Mutant Proteins Human genes 0.000 claims 1
• 108010021466 Mutant Proteins Proteins 0.000 claims 1
• 206010029803 Nosocomial infection Diseases 0.000 claims 1
• 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
• 241000589517 Pseudomonas aeruginosa Species 0.000 claims 1
• 239000000427 antigen Substances 0.000 claims 1
• 102000036639 antigens Human genes 0.000 claims 1
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• 230000021615 conjugation Effects 0.000 claims 1
• 238000003745 diagnosis Methods 0.000 claims 1
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