JP2012523221A - 緑膿菌（Ｐｓｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａ）のＩＡＴＳＯ１血清型のリポ多糖類（ＬＰＳ）に対して特異的なヒトモノクローナル抗体 - Google Patents
緑膿菌（Ｐｓｅｕｄｏｍｏｎａｓａｅｒｕｇｉｎｏｓａ）のＩＡＴＳＯ１血清型のリポ多糖類（ＬＰＳ）に対して特異的なヒトモノクローナル抗体 Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP09005245.7 | 2009-04-09 | ||
| EP09005245 | 2009-04-09 | ||
| PCT/EP2010/002158 WO2010115606A1 (en) | 2009-04-09 | 2010-04-06 | Human monoclonal antibody specific for lipopolysaccarides (lps) of serotype iats 01 of pseudomonas aeruginosa |
Publications (2)
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| JP2012523221A true JP2012523221A (ja) | 2012-10-04 |
| JP2012523221A5 JP2012523221A5 (cg-RX-API-DMAC7.html) | 2013-05-23 |
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| US20130045207A1 (en) * | 2010-02-18 | 2013-02-21 | Symphogen A/S | Antibody against serotype g lipopolysaccharide of pseudomonas aeruginosa |
| PL2718320T3 (pl) * | 2011-06-10 | 2018-06-29 | Medimmune Limited | Cząsteczki wiążące przeciwko PSL Pseudomonas i ich zastosowanie |
| KR102184343B1 (ko) | 2011-11-07 | 2020-11-30 | 메디뮨 엘엘씨 | 항슈도모나스 ｐｓｌ 및 ｐｃｒｖ 결합 분자를 이용한 병용 요법 |
| ES2981535T3 (es) | 2015-11-10 | 2024-10-09 | Visterra Inc | Conjugados de molécula de anticuerpo-fármaco que se unen específicamente al lipopolisacárido y usos de los mismos |
| JP7303110B2 (ja) | 2017-01-18 | 2023-07-04 | ビステラ， インコーポレイテッド | 抗体分子－薬物コンジュゲートおよびその使用 |
| JP2023521319A (ja) | 2020-04-03 | 2023-05-24 | ビステラ， インコーポレイテッド | 抗体分子－薬物コンジュゲートおよびその使用 |
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| US4834975A (en) | 1984-05-25 | 1989-05-30 | Genetics Corporation | Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production |
| US5955584A (en) * | 1986-03-31 | 1999-09-21 | Charter Ventures | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof |
| ES2338105T3 (es) * | 2003-05-14 | 2010-05-04 | Kenta Biotech Ag | Anticuerpo monoclonal humano especifico para lipopolisacaridos (lps) de serotipo iats 06 pseudomonas aeruginosa. |
| EP1690875A1 (en) * | 2005-02-14 | 2006-08-16 | Kenta Biotech AG | Human monoclonal antibody specific for lipopolysaccharides (LPS) of the pseudomonas aeruginosa IATS O11 serotype |
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2010
- 2010-04-06 BR BRPI1013427A patent/BRPI1013427A2/pt not_active IP Right Cessation
- 2010-04-06 KR KR1020117026384A patent/KR20120016086A/ko not_active Withdrawn
- 2010-04-06 MX MX2011010634A patent/MX2011010634A/es not_active Application Discontinuation
- 2010-04-06 JP JP2012503917A patent/JP2012523221A/ja not_active Withdrawn
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Also Published As
| Publication number | Publication date |
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| US20120114657A1 (en) | 2012-05-10 |
| MX2011010634A (es) | 2012-03-06 |
| CN102639562A (zh) | 2012-08-15 |
| WO2010115606A1 (en) | 2010-10-14 |
| CA2758081A1 (en) | 2010-10-14 |
| IL215549A0 (en) | 2011-12-29 |
| KR20120016086A (ko) | 2012-02-22 |
| EP2417157A1 (en) | 2012-02-15 |
| BRPI1013427A2 (pt) | 2016-04-05 |
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