JP2016519664A - ネットワークを基にした微生物組成物及び方法 - Google Patents

ネットワークを基にした微生物組成物及び方法 Download PDF

Info

Publication number
JP2016519664A
JP2016519664A JP2016502561A JP2016502561A JP2016519664A JP 2016519664 A JP2016519664 A JP 2016519664A JP 2016502561 A JP2016502561 A JP 2016502561A JP 2016502561 A JP2016502561 A JP 2016502561A JP 2016519664 A JP2016519664 A JP 2016519664A
Authority
JP
Japan
Prior art keywords
seq
bacteria
clade
group
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016502561A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016519664A6 (enExample
JP2016519664A5 (enExample
Inventor
アール ヘン マシュー
アール ヘン マシュー
エヌ クック デイビッド
エヌ クック デイビッド
ケイ オオスミ トシロウ
ケイ オオスミ トシロウ
ランバルド マッケンジー メリー‐ジェーン
ランバルド マッケンジー メリー‐ジェーン
ディー リトコフスキー ケビン
ディー リトコフスキー ケビン
チャン ハン
チャン ハン
グラント オーニス ジョン
グラント オーニス ジョン
ベリー デイビッド
ベリー デイビッド
Original Assignee
セレス セラピューティクス インコーポレイテッド
セレス セラピューティクス インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セレス セラピューティクス インコーポレイテッド, セレス セラピューティクス インコーポレイテッド filed Critical セレス セラピューティクス インコーポレイテッド
Publication of JP2016519664A publication Critical patent/JP2016519664A/ja
Publication of JP2016519664A5 publication Critical patent/JP2016519664A5/ja
Publication of JP2016519664A6 publication Critical patent/JP2016519664A6/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2016502561A 2013-03-15 2014-03-17 ネットワークを基にした微生物組成物及び方法 Pending JP2016519664A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361798666P 2013-03-15 2013-03-15
US61/798,666 2013-03-15
PCT/US2014/030817 WO2014145958A2 (en) 2013-03-15 2014-03-17 Network-based microbial compositions and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019088423A Division JP7136743B2 (ja) 2013-03-15 2019-05-08 ネットワークを基にした微生物組成物及び方法

Publications (3)

Publication Number Publication Date
JP2016519664A true JP2016519664A (ja) 2016-07-07
JP2016519664A5 JP2016519664A5 (enExample) 2017-02-02
JP2016519664A6 JP2016519664A6 (enExample) 2019-10-17

Family

ID=51538577

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2016502561A Pending JP2016519664A (ja) 2013-03-15 2014-03-17 ネットワークを基にした微生物組成物及び方法
JP2019088423A Active JP7136743B2 (ja) 2013-03-15 2019-05-08 ネットワークを基にした微生物組成物及び方法
JP2022138978A Pending JP2022188020A (ja) 2013-03-15 2022-09-01 ネットワークを基にした微生物組成物及び方法
JP2024141842A Pending JP2024167277A (ja) 2013-03-15 2024-08-23 ネットワークを基にした微生物組成物及び方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019088423A Active JP7136743B2 (ja) 2013-03-15 2019-05-08 ネットワークを基にした微生物組成物及び方法
JP2022138978A Pending JP2022188020A (ja) 2013-03-15 2022-09-01 ネットワークを基にした微生物組成物及び方法
JP2024141842A Pending JP2024167277A (ja) 2013-03-15 2024-08-23 ネットワークを基にした微生物組成物及び方法

Country Status (6)

Country Link
US (3) US10076546B2 (enExample)
EP (1) EP2967077A4 (enExample)
JP (4) JP2016519664A (enExample)
AU (3) AU2014232370B2 (enExample)
HK (1) HK1220326A1 (enExample)
WO (1) WO2014145958A2 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018035153A (ja) * 2016-08-29 2018-03-08 国立大学法人 東京大学 糞便微生物叢を含む組成物
JP2020518284A (ja) * 2017-04-28 2020-06-25 アレン−ベルコー, エマALLEN−VERCOE, Emma 細菌を保管するための方法および組成物
JP2020530493A (ja) * 2017-08-07 2020-10-22 フィンチ セラピューティクス、インコーポレイテッド． 腸内の抗生物質耐性菌を除菌するための組成物及び方法
JP2022541795A (ja) * 2019-07-19 2022-09-27 フィンチ セラピューティクス ホールディングス エルエルシー 胃腸障害の治療のための方法および産物
JP2022551057A (ja) * 2019-10-11 2022-12-07 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 気分障害の改善のためのバイオマーカーとしての２－メチルブチレート
JP2023517024A (ja) * 2020-03-04 2023-04-21 アンスティテュ・ナシオナル・ドゥ・ルシェルシェ・プール・ラグリクルテュール・ラリマンタシオン・エ・ランヴィロンヌマン メタボリックシンドローム及び炎症性腸疾患の処置における使用のためのコプロコッカス（ｃｏｐｒｏｃｏｃｃｕｓ）菌
JP7279983B1 (ja) 2022-09-21 2023-05-23 学校法人近畿大学 腸内細菌培養組培地、及び腸内細菌培養方法。

Families Citing this family (130)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4663746A3 (en) 2010-02-01 2026-04-15 Ferring Microbiome Inc. Bacteriotherapy for clostridium difficile colitis
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
CA2892588A1 (en) 2011-12-01 2013-06-06 School Corporation, Azabu Veterinary Medicine Educational Institution Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
EP2830599B1 (en) 2012-03-29 2018-08-15 Therabiome, Llc Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
MX2015006491A (es) 2012-11-23 2015-12-03 Seres Health Inc Composiciones bacterianas sinergicas y metodos de produccion y uso de las mismas.
MX369877B (es) 2013-02-04 2019-11-25 Seres Therapeutics Inc Composiciones y metodos.
EP2951283A4 (en) 2013-02-04 2017-01-25 Seres Therapeutics, Inc. Compositions and methods
US9907755B2 (en) 2013-03-14 2018-03-06 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
JP2016519664A (ja) 2013-03-15 2016-07-07 セレス セラピューティクス インコーポレイテッド ネットワークを基にした微生物組成物及び方法
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
WO2015013214A2 (en) 2013-07-21 2015-01-29 Whole Biome, Inc. Methods and systems for microbiome characterization, monitoring and treatment
MX367109B (es) 2013-11-25 2019-08-05 Seres Therapeutics Inc Composiciones bacterianas sinergicas y sus metodos de produccion y usos.
US9956282B2 (en) 2013-12-16 2018-05-01 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
EP3134509B1 (en) * 2014-04-23 2026-01-21 Cornell University Modulation of fat storage in a subject by altering population levels of christensenellaceae in the gi tract
US10357157B2 (en) 2014-10-21 2019-07-23 uBiome, Inc. Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features
US10395777B2 (en) 2014-10-21 2019-08-27 uBiome, Inc. Method and system for characterizing microorganism-associated sleep-related conditions
WO2016065075A1 (en) 2014-10-21 2016-04-28 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics
US10346592B2 (en) 2014-10-21 2019-07-09 uBiome, Inc. Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues
EP4529950A3 (en) 2014-10-31 2025-08-20 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
PE20171138A1 (es) 2014-12-23 2017-08-09 4D Pharma Res Ltd Modulacion inmunitaria
DK3193901T3 (en) 2014-12-23 2018-05-28 4D Pharma Res Ltd PIRIN POLYPEPTIDE AND IMMUNMODULATION
HK1246373A1 (zh) * 2015-02-27 2018-09-07 Alere Inc. 微生物群诊断
WO2016183535A1 (en) 2015-05-14 2016-11-17 University Of Puerto Rico Methods for restoring microbiota of newborns
HK1253064A1 (zh) * 2015-06-01 2019-06-06 The University Of Chicago 通过操纵共生微生物菌群对癌症的治疗
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
PL3307289T3 (pl) 2015-06-09 2022-01-17 Rebiotix, Inc. Sposoby wytwarzania kompozycji do terapii przywracającej mikrobiotę (mrt)
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
PE20180243A1 (es) 2015-06-15 2018-01-31 4D Pharma Res Ltd Composiciones que comprenden cepas bacterianas
LT3360559T (lt) 2015-06-15 2019-12-27 4D Pharma Research Limited Kompozicijos, apimančios bakterijų kamienus
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3662917A1 (en) 2015-06-15 2020-06-10 4D Pharma Research Limited Compositions comprising bacterial strains
JP2018531908A (ja) * 2015-09-04 2018-11-01 メモリアル スローン ケタリング キャンサー センター 癌の再発のリスクを検出するための方法及び組成物
MA41013A (fr) 2015-11-20 2017-08-30 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
WO2017117142A1 (en) 2015-12-28 2017-07-06 New York University Device and method of restoring microbiota of newborns
JP2019500035A (ja) * 2015-12-31 2019-01-10 カエルス ファーマシューティカルズ ビー．ヴィ． ユーバクテリウム・ハリー（Ｅｕｂａｃｔｅｒｉｕｍ ｈａｌｌｉｉ）を培養し、保存する方法
CN105524907B (zh) * 2016-02-01 2018-12-04 江南大学 一种底物专一性提高的胆盐水解酶突变体
RS64782B1 (sr) 2016-02-04 2023-11-30 Univ Gent Upotreba mikrobnih zajednica za zdravlje ljudi i životinja
MX373290B (es) 2016-03-04 2020-06-18 4D Pharma Plc Composiciones que comprenden cepas bacterianas.
CN115919906A (zh) 2016-03-04 2023-04-07 加利福尼亚大学董事会 微生物聚生体及其用途
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
WO2017156031A1 (en) * 2016-03-07 2017-09-14 uBiome, Inc. Method and system for characterizing mouth-associated conditions
AU2017234120B2 (en) 2016-03-14 2024-06-20 Holobiome, Inc. Modulation of the gut microbiome to treat mental disorders or diseases of the central nervous system
MY190858A (en) * 2016-04-05 2022-05-12 Nch Corp Nutrient rich germinant composition and spore incubation method
EP3442545A4 (en) * 2016-04-11 2020-01-08 President and Fellows of Harvard College PROBIOTIC FORMULATIONS FOR IMPROVING SPORTS PERFORMANCE
US11766461B2 (en) 2016-04-20 2023-09-26 The Board of Trustees of the Stanford Junior Compositions and methods for nucleic acid expression and protein secretion in Bacteroides
KR102658297B1 (ko) 2016-06-14 2024-04-18 베단타 바이오사이언시즈, 인크. 클로스트리디움 디피실레 감염의 치료
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
KR101815692B1 (ko) 2016-07-25 2018-01-16 주식회사 고바이오랩 구강 세균의 군집을 이용한 대사성 질환 진단용 바이오 마커
US10441612B2 (en) * 2016-08-16 2019-10-15 Taichung Veterans General Hospital Intestinal microbe therapy, composition therefor and method for preparing the same
US10799540B2 (en) * 2016-09-06 2020-10-13 Bgi Shenzhen Faecalibacterium longum and application thereof
US11959125B2 (en) 2016-09-15 2024-04-16 Sun Genomics, Inc. Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
WO2018053308A1 (en) * 2016-09-15 2018-03-22 Sun Genomics Llc Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample
FI20165932L (fi) * 2016-12-07 2018-06-08 Univ Helsinki Immunomodulatorisia koostumuksia
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US11566238B2 (en) 2016-12-15 2023-01-31 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for modulating growth of a genetically modified gut bacterial cell
US10783437B2 (en) * 2017-03-05 2020-09-22 International Business Machines Corporation Hybrid aggregation for deep learning neural networks
US10733214B2 (en) 2017-03-20 2020-08-04 International Business Machines Corporation Analyzing metagenomics data
CA3211208A1 (en) 2017-04-03 2018-10-11 Gusto Global, Llc Rational design of microbial-based biotherapeutics
EP3388069B1 (en) 2017-04-12 2019-05-01 ETH Zurich Consortia of living bacteria useful for treatment of microbiome dysbiosis
MA48940A (fr) 2017-05-22 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41708A (fr) 2017-05-24 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
TWI767013B (zh) 2017-06-14 2022-06-11 英商4D製藥研究有限公司 包含細菌品系之組成物
PL3638271T3 (pl) 2017-06-14 2021-03-22 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
JP2020523326A (ja) 2017-06-14 2020-08-06 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ 細菌株を含む組成物
AU2018253466B2 (en) 2017-07-17 2019-03-28 smartDNA Pty Ltd Method of diagnosing a dysbiosis
AU2018309153A1 (en) * 2017-08-04 2020-03-19 Tarunmeet GUJRAL Roseburia hominis, Eubacterium eligens, and combinations thereof as biotherapeutics
MX2020001501A (es) * 2017-08-06 2020-03-24 Second Genome Inc Streptococcus australis como bioterapeuticos.
BR112020002992A2 (pt) 2017-08-14 2020-08-18 Seres Therapeutics, Inc. composições e métodos para tratamento de doença colestática
WO2019046646A1 (en) 2017-08-30 2019-03-07 Whole Biome Inc. METHODS AND COMPOSITIONS FOR THE TREATMENT OF MICROBIOMA ASSOCIATED DISORDERS
JP2021501185A (ja) * 2017-10-30 2021-01-14 セレス セラピューティクス インコーポレイテッド 抗生物質耐性を処置するための組成物及び方法
MX2020005875A (es) 2017-12-05 2020-10-08 Bioplx Inc Métodos y composiciones para prevenir la infección microbiana.
EP3723775A4 (en) 2017-12-15 2022-04-13 Solarea Bio, Inc. MICROBIAL COMPOSITIONS AND METHODS OF TREATING TYPE 2 DIABETES, OBESITY AND METABOLIC SYNDROME
CN112105371B (zh) * 2018-02-09 2024-12-17 内斯托尔株式会社 脂多糖控制性肠道细菌及其用途
WO2019178494A1 (en) * 2018-03-15 2019-09-19 Evelo Biosciences, Inc. Compositions and methods for treating cancer and inflammation using tyzzerella nexilis
AU2019253714A1 (en) 2018-04-10 2020-11-26 Siolta Therapeutics, Inc. Microbial consortia
CN112292141A (zh) * 2018-04-13 2021-01-29 医学生命探索有限公司 产生长链双羧基脂肪酸(lcdfa)的微生物及其用途
CN113164526A (zh) 2018-07-19 2021-07-23 潘德勒姆治疗公司 用于微生物植入的方法和组合物
CN108977395B (zh) * 2018-07-31 2022-03-22 李昕 钝化固化修复土壤六价铬污染的生物纳米材料的制备方法
JP7558170B2 (ja) 2018-08-17 2024-09-30 ヴェダンタ バイオサイエンシーズ インコーポレーテッド 腸内毒素症を減少させ、微生物叢を復元する方法
WO2020051379A1 (en) 2018-09-05 2020-03-12 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases
US11980647B2 (en) 2018-09-05 2024-05-14 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
US12144834B2 (en) 2018-09-13 2024-11-19 Xbiome Inc. Methods and compositions for treating gastrointestinal and inflammatory disorders
CA3154314A1 (en) 2018-09-13 2020-03-19 Gnubiotics Sciences Sa Microbiome markers and uses thereof
US12414971B2 (en) 2018-09-25 2025-09-16 Duke University Methods and compositions to treat and prevent infection
US20210355546A1 (en) * 2018-11-02 2021-11-18 The Regents Of The University Of California Methods to Diagnose and Treat Cancer Using Non-Human Nucleic Acids
CA3120569A1 (en) * 2018-11-21 2020-05-28 Chan Zuckerberg Biohub, Inc. High-complexity synthetic gut bacterial communities
EP3890505A4 (en) * 2018-12-05 2022-11-02 Seres Therapeutics, Inc. COMPOSITIONS FOR STABILIZING BACTERIA AND THEIR USES
US11980645B2 (en) 2019-01-22 2024-05-14 The Regents Of The University Of California Bile acids and use in disease treatment
US11270791B2 (en) * 2019-03-30 2022-03-08 Tata Chemicals Limited In silico methods for obtaining nutraceutical compositions
CN113853198A (zh) 2019-04-09 2021-12-28 德慕拜昂生物科技公司 用于改善皮肤健康和用于治疗和预防与病原微生物相关联的疾病、疾患和病症的组合物和方法
WO2021033042A1 (en) * 2019-08-16 2021-02-25 Janssen Biotech, Inc. Optimized culture media for clostridia bacteria
AU2020354581A1 (en) 2019-09-24 2022-03-03 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases
JP7624449B2 (ja) * 2019-10-07 2025-01-30 シオルタ・セラピューティクス，インコーポレイテッド 治療用医薬組成物
EP3808358A1 (en) * 2019-10-17 2021-04-21 University College Cork-National University of Ireland, Cork Microbial compositions, strains and methods
IL271775A (en) * 2019-12-31 2021-06-30 Biomica Ltd Microbial consortium and uses thereof
WO2021146632A1 (en) * 2020-01-17 2021-07-22 Second Genome, Inc. Methods and compositions for treating type 2 diabetes
WO2021163212A1 (en) 2020-02-10 2021-08-19 Native Microbials, Inc. Microbial compositions and methods of use for canine enteropathy and dysbiosis
AU2021234298A1 (en) * 2020-03-10 2022-09-29 Federation Bio Inc. Microbial consortia for the treatment of disease
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
GB202007452D0 (en) * 2020-05-19 2020-07-01 Microbiotica Ltd Threrapeutic bacterial composition
EP4152959A4 (en) * 2020-05-21 2024-07-03 Chan Zuckerberg Biohub, Inc. HIGH COMPLEXITY SYNTHETIC GUT BACTERIAL COMMUNITIES
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
EP4189063A4 (en) * 2020-07-28 2024-08-07 Icahn School of Medicine at Mount Sinai COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL TRACT INFECTIONS
CA3188645A1 (en) 2020-08-14 2022-02-17 Prolacta Bioscience, Inc. Human milk oligosaccharide compositions for use with bacteriotherapies
JP7510824B2 (ja) * 2020-09-02 2024-07-04 日清食品ホールディングス株式会社 Ｉｌ－１７の産生を抑制するビフィズス菌
JP2023545458A (ja) * 2020-10-14 2023-10-30 ダームビオント インコーポレイテッド 皮膚の健康状態の改善、ならびに、真菌および他の病原性マイクローブに関連する疾患、障害および疾病の処置および予防のための組成物および方法
AU2021388169A1 (en) * 2020-11-25 2023-07-13 Seres Therapeutics, Inc. Designed bacterial compositions for treating graft-versus-host-disease
KR102296290B1 (ko) * 2020-12-31 2021-09-01 주식회사 바이오뱅크힐링 비피도박테리움 아돌레센티스 균주, 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
EP4304557A4 (en) * 2021-03-12 2025-04-02 MarvelBiome, Inc. METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS, OR METABOLITES FOR THE TREATMENT OF EYE DISORDERS
US12011467B2 (en) 2021-05-18 2024-06-18 J. Craig Venter Institute, Inc. Bacterial formulation
CN113337436A (zh) * 2021-06-09 2021-09-03 中国科学院新疆生态与地理研究所 一种尿素分解菌及其选育方法和应用
CN113493847B (zh) * 2021-06-24 2022-04-19 北京工业大学 基于PMA高通量测序和PICRUSt的抗生素抗性基因及潜在宿主细菌的鉴定方法
EP4436407A1 (en) 2021-11-22 2024-10-02 Solarea Bio, Inc. Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause
US20230190834A1 (en) 2021-12-21 2023-06-22 Solarea Bio, Inc. Immunomodulatory compositions comprising microbial entities
EP4478893A4 (en) * 2022-02-15 2025-05-21 The Regents of the University of California Methods, devices, and systems for determining the functional microbial niche and identifying interventions in complex heterogeneous communities
WO2024026561A2 (en) 2022-08-01 2024-02-08 Novel Biome Solutions Inc. Fecal microbiota transplant methods of manufacture
JP2024076476A (ja) * 2022-11-25 2024-06-06 ノバセル株式会社 Ｔｖｃｍの案を評価するための装置、方法及びそのためのプログラム
WO2025030167A2 (en) * 2023-08-03 2025-02-06 University Of Virginia Patent Foundation Compositions, systems, and methods relating to predictive microbiome transplantation and clostridioides difficile therapies
EP4772608A1 (en) * 2023-08-30 2026-07-08 Ajou University Industry-Academic Cooperation Foundation Bacteroides eggerthii kgmb05336 strain and use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002007741A1 (en) * 2000-07-25 2002-01-31 Borody Thomas J Probiotic recolonisation therapy
WO2011043654A1 (en) * 2009-10-05 2011-04-14 Aak Patent B.V. Methods for diagnosing irritable bowel syndrome
WO2012122478A1 (en) * 2011-03-09 2012-09-13 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
WO2012142605A1 (en) * 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent

Family Cites Families (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3009864A (en) 1958-09-18 1961-11-21 Union Carbide Corp Process control
US3228838A (en) 1959-04-23 1966-01-11 Union Carbide Corp Preservation of biological substances
US3009861A (en) 1961-01-13 1961-11-21 Alderton Gordon Isolation of bacterial spores
US3608030A (en) 1969-05-21 1971-09-21 Howard Tint Method of preparing a tablet dosage-form for the immunization of the intestinal tract with live virus preparations
US4077227A (en) 1976-11-12 1978-03-07 Regents Of The University Of Minnesota Method of freezing liquid material in which agglomeration is inhibited
US4205132A (en) 1978-07-17 1980-05-27 Microlife Technics, Inc. Lyophilization of bacteria
FI59925C (fi) 1980-01-11 1981-11-10 Esko Viljo Nurmi Foerfarande foer framstaellning av ett bakteriepreparat anvaendbart foer foerhindrande av salmonellainfektion hos fjaederfae
US4655047A (en) 1985-03-25 1987-04-07 I.Q.F. Inc. Process for freezing or chilling
JPS61252212A (ja) 1985-04-12 1986-11-10 Mitsubishi Petrochem Co Ltd 高吸水性ポリマ−の製造方法
US4839281A (en) 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
JP2733849B2 (ja) 1987-10-12 1998-03-30 ボロディー，ソーマス・ユリウス 胃腸障害治療のための改良された方法
US5045446A (en) 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
DE68928665T2 (de) 1988-08-02 1998-11-12 Gastro Services Pty Ltd Behandlung von gastro-intestinalen krankheiten
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
GB2233343B (en) 1989-06-30 1993-07-07 Farmos Oy A bacterial preparation for use in poultry
JP2961182B2 (ja) 1990-03-09 1999-10-12 ミヤリサン株式会社 クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物
JP2961184B2 (ja) 1990-05-07 1999-10-12 ミヤリサン株式会社 クロストリジウム・ディフィシル下痢症および偽膜性大腸炎の予防ならびに治療用医薬組成物
US5436002A (en) 1991-01-29 1995-07-25 Mycogen Corporation Bacillus thuringiensisisolate PS201T6 toxin
RU2035186C1 (ru) 1992-07-09 1995-05-20 Семен Рафаилович Резник Профилактический биопрепарат споролакт
KR950703640A (ko) 1992-10-09 1995-09-20 가일 케이,나우톤. 간 보존 세포(liver reserve cells)
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
EP0952773B1 (en) 1995-09-15 2005-11-23 Dale N. Gerding Methods and compositions for prevention and treatment of clostridium difficile-associated diseases
AUPO430496A0 (en) 1996-12-19 1997-01-23 Arnott's Biscuits Limited Prebiotics and probiotics
US5965128A (en) 1997-08-13 1999-10-12 University Of Georgia Research Foundation Inc. Control of enterohemorrhagic E. coli 0157:H7 in cattle by probiotic bacteria and specific strains of E. coli
US5951977A (en) 1997-10-14 1999-09-14 The United States Of America, As Represented By The Secretary Of Agriculture Competitive exclusion culture for swine
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
US6589771B1 (en) 1999-10-28 2003-07-08 Immunom Technologies, Inc. Methods for arousing dormant bacteria
US20030118547A1 (en) 2000-01-27 2003-06-26 Vandenberg Grant William Composition for intestinal delivery
US6613549B2 (en) 2000-02-10 2003-09-02 Urex Biotech, Inc. Probiotic therapy for newborns
US20040170617A1 (en) 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
CA2430292A1 (en) 2000-11-30 2002-06-06 The Bio Balance Corp. Preparation of compositions comprising bacterial strains and volatile plant extracts and therapeutic and industrial applications thereof
EP1527164A4 (en) 2001-05-04 2006-02-01 Univ Florida CLONING AND SEQUENCING OF PYRUVATE CARBOXYLASE (PDC) GENES FROM BACTERIA AND USES THEREOF
ITMI20011632A1 (it) 2001-07-27 2003-01-27 Sanofi Synthelabo Composizione solida contenente spore di batteri non patogeni del genere bacillus
GB0130789D0 (en) 2001-12-21 2002-02-06 King S College London Application of spores
US8383342B2 (en) 2002-04-24 2013-02-26 The University Of North Carolina At Greensboro Compositions, products, methods and systems to monitor water and other ecosystems
GB0212975D0 (en) 2002-06-06 2002-07-17 Mars Uk Ltd Mammalian animal composition
AU2002951692A0 (en) 2002-09-23 2002-10-17 Vital Biotech (Hong Kong) Limited Improvements in or relating to vaccines
US20050180962A1 (en) 2003-01-30 2005-08-18 Eyal Raz Inactivated probiotic bacteria and methods of use thereof
WO2004101770A1 (en) 2003-03-13 2004-11-25 Universite De Moncton (Bureau De Soutien A L'innovation) Antioxidant producing bacterium and uses thereof
CA2522957C (en) 2003-04-23 2013-10-22 Medarex, Inc. Compositions and methods for the therapy of inflammatory bowel disease
EP1473370A3 (en) 2003-04-24 2005-03-09 BioMerieux, Inc. Genus, group, species and/or strain specific 16S rDNA Sequences
WO2004104175A2 (en) 2003-05-14 2004-12-02 University Of Georgia Research Foundation, Inc. Probiotic bacteria and methods
AU2004265511A1 (en) 2003-08-18 2005-02-24 The Bio Balance Corporation A stable liquid probiotic composition, preparation and applications thereof
US7731976B2 (en) 2003-08-29 2010-06-08 Cobb And Company, Llp Treatment of irritable bowel syndrome using probiotic composition
US20050048515A1 (en) 2003-08-29 2005-03-03 Garner Bryan E. Methods for detecting and quantifying specific probiotic microorganisms in animal feed
US20050239706A1 (en) 2003-10-31 2005-10-27 Washington University In St. Louis Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
CN1913787B (zh) 2004-02-03 2014-11-26 增值研究合伙有限公司 在动物中促进生长的活体细菌的应用
US7632520B2 (en) 2004-02-16 2009-12-15 Sanjeev Khandelwal Synergistic antibacterial formulation and to a method of making the same
US7854927B2 (en) 2004-05-11 2010-12-21 Ganeden Biotech, Inc. Methods and compositions for the dietary management of autoimmune disorders
US7521201B2 (en) 2004-11-01 2009-04-21 Strategic Diagnostics Inc. Bacteriophages as selective agents
EP1815016B1 (en) 2004-11-01 2012-06-27 George Mason University Compositions and methods for diagnosing colon disorders
US20060188523A1 (en) 2005-01-10 2006-08-24 Zhiheng Pei Methods for diagnosing and treating chronic tonsillitis
US7993667B2 (en) 2005-03-25 2011-08-09 Kimberly-Clark Worldwide, Inc. Methods of manufacturing a medicated tampon assembly
JP4938006B2 (ja) 2005-05-31 2012-05-23 ザ・アイムス・カンパニー ネコ科動物プロバイオティク・ビフィドバクテリア
US7452872B2 (en) 2005-08-24 2008-11-18 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
DK1931363T3 (en) 2005-09-28 2016-02-22 Nordisk Rebalance As Treatment of IBD using both probiotic bacteria and fermented cereal as behandlingseffektorer
US8968721B2 (en) 2005-12-28 2015-03-03 Advanced Bionutrition Corporation Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
EP2035544A2 (en) 2006-05-18 2009-03-18 Biobalance Llc Bacterial strains, compositions including same and probiotic use thereof
JP5019563B2 (ja) 2006-06-16 2012-09-05 旭化成ケミカルズ株式会社 腸内細菌賦活剤
JP2009541298A (ja) 2006-06-20 2009-11-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 胃腸障害を処置するための電子カプセル
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
EE05459B1 (et) 2006-12-08 2011-08-15 Tartu �likool Sporogeense Bacillus smithii tvi TBMI12 MSCL P737 ja selle endospooride kasutamine probiootikumina, toidulisandina ning probiootiline kompositsioon
WO2008076696A2 (en) 2006-12-18 2008-06-26 Washington University In St. Louis The gut microbiome as a biomarker and therapeutic target for treating obesity or an obesity related disorder
DE102006062250A1 (de) 2006-12-22 2008-06-26 Roland Saur-Brosch Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden
WO2008083157A2 (en) 2006-12-29 2008-07-10 Washington University In St. Louis Altering pgc-1alapha, ampk, fiaf, or the gastrointestinal microbiota as a means to modulate body fat and/or weight loss in a subject
US8518873B2 (en) 2007-09-12 2013-08-27 The Medicines Company Method of inhibiting clostridium difficile by administration of oritavancin
US8469648B2 (en) * 2007-10-24 2013-06-25 T&T Engineering Services Apparatus and method for pre-loading of a main rotating structural member
JP2011503232A (ja) 2007-11-20 2011-01-27 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド 免疫応答の調節
US8236508B2 (en) 2008-01-29 2012-08-07 Drexel University Detecting and measuring live pathogens utilizing a mass detection device
US8021654B2 (en) 2008-03-14 2011-09-20 Danisco A/S Methods of treating pigs with Bacillus strains
RU2010144789A (ru) 2008-04-01 2012-05-10 Метаметрикс Клиникал Лэборетери (Us) Процесс и способ мониторинга желудочно-кишечной микрофлоры
CN102940652B (zh) 2008-05-28 2015-03-25 青岛东海药业有限公司 两形真杆菌制剂及其应用
EP2313773A1 (en) 2008-07-15 2011-04-27 Metanomics Health GmbH Means and methods diagnosing gastric bypass and conditions related thereto
CN102131928A (zh) 2008-08-26 2011-07-20 奥林巴斯株式会社 粪便试样的调制方法、粪便试样调制用溶液、及粪便采集用试剂盒
WO2010030997A1 (en) 2008-09-12 2010-03-18 The Washington University Regulating intestinal microbiota dependent signaling as a means to modulate body fat and/or weight loss
WO2010036876A2 (en) 2008-09-25 2010-04-01 New York University Compositions and methods for characterizing and restoring gastrointestinal, skin, and nasal microbiota
EP2367839A4 (en) 2008-11-03 2012-07-04 Univ Tufts METHOD AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORTS NUTRITION AND GROWTH
GB0821913D0 (en) 2008-12-02 2009-01-07 Price & Co Antibacterial compounds
IT1393931B1 (it) 2009-02-25 2012-05-17 Neuroscienze Pharmaness S C A R L Composizione di spore di batteri non patogeni
US20120128633A1 (en) 2009-04-30 2012-05-24 Campagnie Gervaise Donone Use of collinsella aerofaciens for reducing bloating
DK2419114T4 (da) 2009-05-01 2019-05-27 Uas Laboratories Llc Bakteriesammensætninger til profylakse og behandling af degenerative sygdomme
US9050276B2 (en) 2009-06-16 2015-06-09 The Trustees Of Columbia University In The City Of New York Autism-associated biomarkers and uses thereof
WO2011046614A2 (en) 2009-10-16 2011-04-21 The Regents Of The University Of California Methods and systems for phylogenetic analysis
US20120165215A1 (en) 2009-06-26 2012-06-28 The Regents Of The University Of California Methods and systems for phylogenetic analysis
WO2011005756A1 (en) 2009-07-06 2011-01-13 Puretech Ventures, Llc Delivery of agents targeted to microbiota niches
MX2012002039A (es) 2009-08-18 2012-04-11 Nestec Sa Una composicion nutricional que comprende cepas de lactococcus y que reduce los sintomas de la alergia, especialmente en infantes y en niños.
WO2011022542A2 (en) 2009-08-19 2011-02-24 Puretech Ventures, Llc Administration of factors normally present in a microbial niche to improve health
US20120149584A1 (en) 2009-08-21 2012-06-14 Bernat Olle Methods of diagnosing and treating microbiome-associated disease using interaction network parameters
GB0916335D0 (en) 2009-09-17 2009-10-28 Martin W J Medicaments
ES2660008T3 (es) 2009-09-23 2018-03-20 Thomas Julius Borody Terapia para infecciones entéricas crónicas
US20110081320A1 (en) 2009-10-06 2011-04-07 Nubiome, Inc. Treatment/Cure of Autoimmune Disease
US20120276149A1 (en) 2009-10-15 2012-11-01 Dan Littman Methods for modulating bacterial infection
DK2498626T3 (en) 2009-11-12 2015-07-13 Nestec Sa FOOD COMPOSITION TO PROMOTE GAS MICROFLORAL BALANCE AND HEALTH
MX348611B (es) 2009-12-31 2017-06-21 Milton Trachtman Ira Forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a una infección bacteriana.
US9492487B2 (en) 2010-02-01 2016-11-15 Matthew Ryan Garner Microbial product containing multiple microorganisms
EP4663746A3 (en) 2010-02-01 2026-04-15 Ferring Microbiome Inc. Bacteriotherapy for clostridium difficile colitis
US20130230498A1 (en) 2010-02-16 2013-09-05 Arizona Board Of Regents For And On Behalf Of Arizona State University Reducing short-chain fatty acids and energy uptake in obese humans by managing their intestinal microbial communities
CA2791464A1 (en) 2010-03-01 2011-09-09 Institut National De La Recherche Agronomique Method of diagnosis of obesity
CN102939391A (zh) 2010-03-01 2013-02-20 国家农艺研究院 炎症性肠病的诊断方法
IT1398553B1 (it) 2010-03-08 2013-03-01 Probiotical Spa Composizione comprendente batteri probiotici per il trattamento di patologie associate con le alterazioni del sistema immunitario.
WO2011113801A1 (en) 2010-03-16 2011-09-22 Universiteit Gent Use of clostridium perfringens strain 23 to protect against necrotic enteritis
US8951512B2 (en) 2010-05-04 2015-02-10 New York University Methods for treating bone disorders by characterizing and restoring mammalian bacterial microbiota
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性ｔ細胞の増殖または集積を誘導する作用を有する組成物
US10487332B2 (en) 2010-07-06 2019-11-26 Glaxosmithkline Biologicals Sa Immunisation of large mammals with low doses of RNA
BR112013001107B1 (pt) 2010-07-16 2022-01-25 The Board Of Trustees Of The University Of Arkansas Métodos e composições incluindo bactéria formadora de esporos para aumento da saúde dos animais
FI20105825A7 (fi) 2010-07-26 2012-01-27 Suomen Punainen Risti Veripalvelu Veriryhmästatuksen käyttö III
CA2807242C (en) 2010-08-04 2017-05-02 Thomas Julius Borody Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
WO2012024638A2 (en) 2010-08-20 2012-02-23 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
US20130224164A1 (en) 2010-09-10 2013-08-29 Viropharma Incorporated Environmental Clostridial Bacteriotherapy and Related Formulations and Methods of Manufacture and Use
EP2646567A4 (en) 2010-10-04 2014-03-26 British Columbia Cancer Agency DETECTION OF FUSOBACTERIUM IN A GASTROINTESTINAL SAMPLE FOR THE DIAGNOSIS OF GASTROINTESTINAL CARCINOMA
EP2662078A1 (en) 2010-11-10 2013-11-13 National Jewish Health Methods to Treat Allergic Conditions
US20120064592A1 (en) 2011-01-26 2012-03-15 Qteros, Inc. Biocatalysts synthesizing deregulated cellulases
CN103491969A (zh) 2011-02-09 2014-01-01 拉维沃公司 恢复和重建肠道微生物群的合生素组合物
TW201247875A (en) 2011-02-25 2012-12-01 Tricorder Diagnostics Llc Microbial signatures as indicators of radiation exposure
WO2012122522A2 (en) 2011-03-09 2012-09-13 Washington University Cultured collection of gut microbial community
US20120276056A1 (en) 2011-04-26 2012-11-01 Wieslaw Janusz Bochenek Method for Use of Biologic Agents Including Live or Dormant Forms of Bacteria and other organisms in Treating Infections, Inflammation and Other Diseases of Distal Small Intestine and Large Intestine
WO2012159023A2 (en) 2011-05-19 2012-11-22 Virginia Commonwealth University Gut microflora as biomarkers for the prognosis of cirrhosis and brain dysfunction
US9579353B2 (en) 2011-06-10 2017-02-28 Prothera, Inc. Pharmaceutical compositions containing pediococcus and methods for reducing the symptoms of gastroenterological syndromes
WO2013008102A2 (en) 2011-07-14 2013-01-17 R.E.D. Laboratories N.V../ S.A. Methods and compositions for evaluating and/or treating chronic immune diseases
US20130022575A1 (en) 2011-07-19 2013-01-24 Microbial Rx Systems and methods of replacing intestinal flora
US20140348811A1 (en) 2011-07-27 2014-11-27 Max International, Llc Compositions comprising sugar-cysteine products
WO2013019896A1 (en) 2011-08-01 2013-02-07 Symbiotix Biotherapies, Inc. Platform for identifying and/or characterizing immunomodulatory agents
CA2851602C (en) 2011-08-30 2020-07-14 Academisch Medisch Centrum Method for preventing and/or treating insulin resistance
EP2756071B1 (en) 2011-09-14 2017-12-20 University Of Guelph Media supplements and methods to culture human gastrointestinal anaerobic microorganisms
US20130121968A1 (en) 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
US20130115232A1 (en) 2011-10-03 2013-05-09 Fred Hutchinson Cancer Research Center Methods for detecting graft-versus-host disease
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
DK2750682T3 (en) 2011-10-11 2016-08-22 Achim Biotherapeutics Ab A composition comprising anaerobically cultured human intestinal flora
CA2892588A1 (en) 2011-12-01 2013-06-06 School Corporation, Azabu Veterinary Medicine Educational Institution Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
GB201201766D0 (en) 2012-02-01 2012-03-14 Imp Innovations Ltd Method
WO2013166031A1 (en) 2012-04-30 2013-11-07 The Washington University Method of isolating and characterizing microorganisms that are targets of host immune responses
US10130665B2 (en) 2012-05-18 2018-11-20 Genome Research Limited Method for identifying bacteria for bacteriotherapy
US9719144B2 (en) 2012-05-25 2017-08-01 Arizona Board Of Regents Microbiome markers and therapies for autism spectrum disorders
US10722577B2 (en) 2012-05-25 2020-07-28 Sloan Kettering Institute For Cancer Research Methods for treating GI syndrome and graft versus host disease
EP2684469A1 (en) 2012-07-13 2014-01-15 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Methods for strengthening and assessment of the natural defence of the colon against C. difficile overgrowth
MX2015006491A (es) 2012-11-23 2015-12-03 Seres Health Inc Composiciones bacterianas sinergicas y metodos de produccion y uso de las mismas.
MX369877B (es) 2013-02-04 2019-11-25 Seres Therapeutics Inc Composiciones y metodos.
EP2951283A4 (en) 2013-02-04 2017-01-25 Seres Therapeutics, Inc. Compositions and methods
US20160040215A1 (en) 2013-03-14 2016-02-11 Seres Therapeutics, Inc. Methods for Pathogen Detection and Enrichment from Materials and Compositions
JP2016519664A (ja) 2013-03-15 2016-07-07 セレス セラピューティクス インコーポレイテッド ネットワークを基にした微生物組成物及び方法
US9962415B2 (en) 2013-05-03 2018-05-08 Nestec S.A. Lachnospiraceae in the gut microbiota and association with body weight
WO2015018307A1 (en) 2013-08-06 2015-02-12 Bgi Shenzhen Co., Limited Biomarkers for colorectal cancer
MX367109B (es) 2013-11-25 2019-08-05 Seres Therapeutics Inc Composiciones bacterianas sinergicas y sus metodos de produccion y usos.
US9956282B2 (en) 2013-12-16 2018-05-01 Seres Therapeutics, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
US20180200308A1 (en) 2015-07-08 2018-07-19 Seres Therapeutics, Inc. Methods of treating colitis
US10300043B2 (en) 2015-08-12 2019-05-28 Mayo Foundation For Medical Education And Research Method for treating a gastrointestinal disorder in a mammal using bacteroides thetaiotaomicron and compositions thereof
WO2017074257A1 (en) 2015-10-26 2017-05-04 Nanyang Technological University Non-viable derivatives of clostridium sporogenes as anti-cancer therapeutic agents
US20190247447A1 (en) 2015-11-24 2019-08-15 Seres Therapeutics, Inc. Designed bacterial compositions
EP3379935A4 (en) 2015-11-25 2019-08-28 Memorial Sloan-Kettering Cancer Center METHOD AND COMPOSITIONS FOR REDUCING VANCOMYCIN RESISTANT ENTEROKOKKEN
US20180369297A1 (en) 2015-12-14 2018-12-27 Metabogen Ab Treatment of intrahepatic cholestasis and related liver diseases
AU2017234120B2 (en) 2016-03-14 2024-06-20 Holobiome, Inc. Modulation of the gut microbiome to treat mental disorders or diseases of the central nervous system
AU2018346255A1 (en) 2017-10-03 2020-04-23 Seres Therapeutics, Inc. Manipulation of tryptamine metabolism
JP2021501185A (ja) 2017-10-30 2021-01-14 セレス セラピューティクス インコーポレイテッド 抗生物質耐性を処置するための組成物及び方法
KR20210024481A (ko) 2018-05-24 2021-03-05 세레스 테라퓨틱스, 인코포레이티드 설계된 박테리아 조성물 및 이의 용도

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002007741A1 (en) * 2000-07-25 2002-01-31 Borody Thomas J Probiotic recolonisation therapy
WO2011043654A1 (en) * 2009-10-05 2011-04-14 Aak Patent B.V. Methods for diagnosing irritable bowel syndrome
WO2012122478A1 (en) * 2011-03-09 2012-09-13 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
WO2012142605A1 (en) * 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLIN. INFECT. DIS., vol. 36, JPN6018003432, 2003, pages 580 - 585, ISSN: 0003947298 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018035153A (ja) * 2016-08-29 2018-03-08 国立大学法人 東京大学 糞便微生物叢を含む組成物
JP2020518284A (ja) * 2017-04-28 2020-06-25 アレン−ベルコー, エマALLEN−VERCOE, Emma 細菌を保管するための方法および組成物
JP2020530493A (ja) * 2017-08-07 2020-10-22 フィンチ セラピューティクス、インコーポレイテッド． 腸内の抗生物質耐性菌を除菌するための組成物及び方法
JP2022541795A (ja) * 2019-07-19 2022-09-27 フィンチ セラピューティクス ホールディングス エルエルシー 胃腸障害の治療のための方法および産物
US12290538B2 (en) 2019-07-19 2025-05-06 Finch Therapeutics Holdings Llc Methods and products for treatment of gastrointestinal disorders
JP2022551057A (ja) * 2019-10-11 2022-12-07 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 気分障害の改善のためのバイオマーカーとしての２－メチルブチレート
JP7607036B2 (ja) 2019-10-11 2024-12-26 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 気分障害の改善のためのバイオマーカーとしての２－メチルブチレート
JP2023517024A (ja) * 2020-03-04 2023-04-21 アンスティテュ・ナシオナル・ドゥ・ルシェルシェ・プール・ラグリクルテュール・ラリマンタシオン・エ・ランヴィロンヌマン メタボリックシンドローム及び炎症性腸疾患の処置における使用のためのコプロコッカス（ｃｏｐｒｏｃｏｃｃｕｓ）菌
JP7279983B1 (ja) 2022-09-21 2023-05-23 学校法人近畿大学 腸内細菌培養組培地、及び腸内細菌培養方法。
JP2024044791A (ja) * 2022-09-21 2024-04-02 学校法人近畿大学 腸内細菌培養組培地、及び腸内細菌培養方法。

Also Published As

Publication number Publication date
AU2014232370B2 (en) 2018-11-01
JP2019163285A (ja) 2019-09-26
HK1220326A1 (zh) 2017-05-05
WO2014145958A3 (en) 2015-01-29
AU2019200628A1 (en) 2019-02-21
US11666612B2 (en) 2023-06-06
AU2014232370A1 (en) 2015-11-05
AU2019200628B2 (en) 2021-02-25
JP2024167277A (ja) 2024-12-03
WO2014145958A2 (en) 2014-09-18
EP2967077A2 (en) 2016-01-20
CA2906921A1 (en) 2014-09-18
AU2021203396A1 (en) 2021-06-24
JP2022188020A (ja) 2022-12-20
US10881696B2 (en) 2021-01-05
US20210252079A1 (en) 2021-08-19
JP7136743B2 (ja) 2022-09-13
WO2014145958A4 (en) 2015-04-02
US20160030494A1 (en) 2016-02-04
EP2967077A4 (en) 2016-09-14
US20180353554A1 (en) 2018-12-13
US10076546B2 (en) 2018-09-18

Similar Documents

Publication Publication Date Title
US11666612B2 (en) Network-based microbial compositions and methods
JP7409743B2 (ja) 病原性細菌生育の抑制のための組成物および方法
JP2016519664A5 (enExample)
EP3074027B1 (en) Synergistic bacterial compositions and methods of production and use thereof
CA2906921C (en) Network-based microbial compositions and methods

Legal Events

Date Code Title Description
A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20160614

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161130

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170315

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20170612

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20170628

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180206

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20180507

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180724

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20190108