MX348611B - Forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a una infección bacteriana. - Google Patents
Forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a una infección bacteriana.Info
- Publication number
- MX348611B MX348611B MX2012007735A MX2012007735A MX348611B MX 348611 B MX348611 B MX 348611B MX 2012007735 A MX2012007735 A MX 2012007735A MX 2012007735 A MX2012007735 A MX 2012007735A MX 348611 B MX348611 B MX 348611B
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- treatment
- inflammatory bowel
- bowel disease
- prophylaxis
- Prior art date
Links
- 208000022559 Inflammatory bowel disease Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title 1
- 239000006041 probiotic Substances 0.000 abstract 3
- 235000018291 probiotics Nutrition 0.000 abstract 3
- 230000003115 biocidal effect Effects 0.000 abstract 2
- 230000000529 probiotic effect Effects 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 230000002939 deleterious effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a una forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a infección bacteriana, en donde dicha forma de dosificación comprende: (i) un componente de liberación retardada comprendiendo una cantidad de antibiótico efectiva para reducir la colonización de bacterias patogénicas en el tracto gastrointestinal, comprendiendo dicho antibiótico una combinación de sulfametoxazol, y trimetoprim; y (ii) un componente de liberación inmediata que comprende una formulación de probióticos en una cantidad efectiva para restaurar las colonias de microflora normal en el intestino, en donde dicho componente de liberación inmediata libera dicha formulación de probióticos luego del contacto con el fluido en el estómago; y en donde dicho componente de liberación retardada libera dicho antibiótico a un pH de 7 o mayor.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29147409P | 2009-12-31 | 2009-12-31 | |
| PCT/US2010/062339 WO2011082218A1 (en) | 2009-12-31 | 2010-12-29 | Compositions and method for treatment and prophylaxis of inflammatory bowel disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2012007735A MX2012007735A (es) | 2012-09-28 |
| MX348611B true MX348611B (es) | 2017-06-21 |
Family
ID=44226799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2012007735A MX348611B (es) | 2009-12-31 | 2010-12-29 | Forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a una infección bacteriana. |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US9138441B2 (es) |
| EP (1) | EP2519108A4 (es) |
| AU (1) | AU2010339573B2 (es) |
| CA (1) | CA2785658C (es) |
| IL (1) | IL220613B (es) |
| MX (1) | MX348611B (es) |
| WO (1) | WO2011082218A1 (es) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX348611B (es) | 2009-12-31 | 2017-06-21 | Milton Trachtman Ira | Forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a una infección bacteriana. |
| WO2012012146A2 (en) * | 2010-06-30 | 2012-01-26 | The Regents Of The University Of Colorado | Compositions and methods to modulate progression and onset of inflammatory bowel disease |
| US10307167B2 (en) | 2012-12-14 | 2019-06-04 | Corquest Medical, Inc. | Assembly and method for left atrial appendage occlusion |
| US10813630B2 (en) | 2011-08-09 | 2020-10-27 | Corquest Medical, Inc. | Closure system for atrial wall |
| US10314594B2 (en) | 2012-12-14 | 2019-06-11 | Corquest Medical, Inc. | Assembly and method for left atrial appendage occlusion |
| WO2013036290A1 (en) * | 2011-09-09 | 2013-03-14 | Yale University | Compositions and methods for assessing and treating inflammatory diseases and disorders |
| CN103082292B (zh) * | 2011-11-02 | 2015-03-04 | 深圳华大基因研究院 | 罗斯氏菌(Roseburia)在治疗和预防肥胖相关疾病中的应用 |
| WO2014011233A1 (en) * | 2012-07-09 | 2014-01-16 | Trachtman Ira Milton | Compositions and method for treatment and prophylaxis of inflammatory bowel disease |
| SE1251123A1 (sv) * | 2012-10-05 | 2014-04-06 | Indevex Ab Publ | Födoämnesprodukt |
| US20140142689A1 (en) | 2012-11-21 | 2014-05-22 | Didier De Canniere | Device and method of treating heart valve malfunction |
| DK3628161T3 (da) | 2012-11-23 | 2023-05-30 | Seres Therapeutics Inc | Synergistiske bakterielle sammensætninger og fremgangsmåder til fremstilling og anvendelse deraf |
| US8906668B2 (en) | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
| AU2014212004B2 (en) | 2013-02-04 | 2018-09-20 | Société des Produits Nestlé S.A. | Compositions for treating or preventing or reducing the severity of clostridium difficile related diseases |
| WO2014121304A1 (en) | 2013-02-04 | 2014-08-07 | Seres Health, Inc. | Compositions and methods |
| EP2967077A4 (en) | 2013-03-15 | 2016-09-14 | Seres Therapeutics Inc | NETWORK-BASED MICROBIAL COMPOSITIONS AND METHOD |
| US20160206564A1 (en) * | 2013-09-27 | 2016-07-21 | Ira Milton Trachtman | Compositions and methods for treatment and prophylaxis of gastrointestinal diseases |
| KR102611070B1 (ko) | 2013-11-25 | 2023-12-07 | 세레스 테라퓨틱스, 인코포레이티드 | 상승적 박테리아 조성물 및 그것의 생산 방법 및 용도 |
| US9566443B2 (en) | 2013-11-26 | 2017-02-14 | Corquest Medical, Inc. | System for treating heart valve malfunction including mitral regurgitation |
| US9956282B2 (en) | 2013-12-16 | 2018-05-01 | Seres Therapeutics, Inc. | Bacterial compositions and methods of use thereof for treatment of immune system disorders |
| US10799541B2 (en) | 2014-07-01 | 2020-10-13 | Probi USA, Inc. | Bi-layer dual release probiotic tablets |
| US10842626B2 (en) | 2014-12-09 | 2020-11-24 | Didier De Canniere | Intracardiac device to correct mitral regurgitation |
| KR20180030459A (ko) * | 2015-03-09 | 2018-03-23 | 바이오이뮤나이저 에스에이지엘 | 항산화제와 비피도박테리아 및 프로바이오틱스로부터 분리된 세포벽이 조합된 조합물을 포함하는 항-노화 조성물 |
| JP7111700B2 (ja) | 2016-09-16 | 2022-08-02 | デュポン ニュートリション バイオサイエンシーズ エーピーエス | 細菌 |
| MX2020001774A (es) | 2017-08-14 | 2020-09-09 | Seres Therapeutics Inc | Composiciones y métodos para tratar enfermedad colestásica. |
| BR112020008552A2 (pt) | 2017-10-30 | 2020-12-29 | Seres Therapeutics, Inc. | métodos e composições para tratamento de resistência a antibiótico |
| US12163135B2 (en) | 2017-12-05 | 2024-12-10 | BioPlx, Inc. | Methods and compositions to prevent microbial infection |
| CN109170163A (zh) * | 2018-09-29 | 2019-01-11 | 华南农业大学 | 一种含有纳豆芽孢杆菌的高效饲料添加剂 |
| US11813296B2 (en) * | 2018-10-04 | 2023-11-14 | Deerland Enzymes, Inc. | Bacillus subtilis probiotics and methods of use for improving immune function, hormonal status, and physical performance |
| JP2022504792A (ja) * | 2018-10-10 | 2022-01-13 | セルバトゥス リミテッド | 炎症性疾患及び関連する感染の治療方法 |
| CN114225024B (zh) * | 2021-12-29 | 2022-08-19 | 山东健袖生态科技有限公司 | 一种用于治疗疾病的益生菌药物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6461607B1 (en) | 1998-08-24 | 2002-10-08 | Ganeden Biotech, Inc. | Probiotic, lactic acid-producing bacteria and uses thereof |
| ATE290391T1 (de) | 1998-12-11 | 2005-03-15 | Urex Biotech Inc | Orale verabreichung von laktobacillus zur behandlung und prävention von urogenitalen infektionen |
| US8048924B2 (en) * | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
| IL152127A0 (en) | 2002-10-06 | 2003-05-29 | Bio Balance Corp | Probiotic compositions for the treatment of inflammatory bowel disease |
| WO2004069156A2 (en) * | 2003-01-30 | 2004-08-19 | The Regents Of The University Of California | Inactivated probiotic bacteria and methods of use thereof |
| ES2713954T3 (es) | 2004-05-14 | 2019-05-24 | Merck Sharp & Dohme | Tratamiento de enfermedades asociadas al uso de antibióticos |
| EP1931363B1 (en) * | 2005-09-28 | 2015-11-18 | Nordisk Rebalance A/S | Treatment of ibd using both probiotic bacteria and fermented cereal as treatment effectors |
| WO2007081981A2 (en) * | 2006-01-11 | 2007-07-19 | Attune Foods | Probiotic food, process for its preparation and dietary regimen |
| US20070298018A1 (en) * | 2006-06-23 | 2007-12-27 | Lacpro Industries, Llc | Novel lactobacillus bulgaricus strain and compositions |
| JP5140154B2 (ja) | 2007-06-27 | 2013-02-06 | アストラゼネカ・アクチエボラーグ | ピラジノン誘導体および肺疾患の処置におけるそれらの使用 |
| US20090098088A1 (en) | 2007-10-10 | 2009-04-16 | The Procter & Gamble Company | Methods And Kits For The Treatment Of Diverticular Conditions |
| WO2009092810A2 (en) * | 2008-01-24 | 2009-07-30 | Bacterfield Oü | Single pharmaceutical composition containing antibiotics and probiotics |
| RU2010143460A (ru) | 2008-05-01 | 2012-06-10 | Дзе Проктер Энд Гэмбл Компани (US) | Способы и наборы для терапии восстановительных состояний кишечника |
| WO2009158384A1 (en) * | 2008-06-27 | 2009-12-30 | The Procter & Gamble Company | Methods and kits for the treatment inhibition, and maintenance of gastrointestinal disorders |
| EP2485742A4 (en) * | 2009-10-06 | 2013-03-20 | Scott Dorfner | ANTIBIOTIC FORMULATIONS WITH REDUCED SIDE EFFECTS ON STOMACH AND DARM |
| PE20121185A1 (es) | 2009-10-27 | 2012-09-15 | Lupin Ltd | Dispersion solida de rifaximina |
| MX348611B (es) | 2009-12-31 | 2017-06-21 | Milton Trachtman Ira | Forma de dosificación oral para usarse en el tratamiento de enfermedad inflamatoria de intestino debido a una infección bacteriana. |
-
2010
- 2010-12-29 MX MX2012007735A patent/MX348611B/es active IP Right Grant
- 2010-12-29 WO PCT/US2010/062339 patent/WO2011082218A1/en not_active Ceased
- 2010-12-29 EP EP10841670.2A patent/EP2519108A4/en not_active Withdrawn
- 2010-12-29 CA CA2785658A patent/CA2785658C/en not_active Expired - Fee Related
- 2010-12-29 US US13/517,486 patent/US9138441B2/en not_active Expired - Fee Related
- 2010-12-29 AU AU2010339573A patent/AU2010339573B2/en not_active Ceased
-
2012
- 2012-06-24 IL IL220613A patent/IL220613B/en active IP Right Grant
-
2015
- 2015-09-18 US US14/857,933 patent/US9492488B2/en not_active Expired - Fee Related
-
2016
- 2016-10-13 US US15/292,300 patent/US9649348B2/en not_active Expired - Fee Related
-
2017
- 2017-05-11 US US15/592,786 patent/US20170246226A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20160000839A1 (en) | 2016-01-07 |
| CA2785658A1 (en) | 2011-07-07 |
| EP2519108A1 (en) | 2012-11-07 |
| US9492488B2 (en) | 2016-11-15 |
| AU2010339573B2 (en) | 2014-08-28 |
| CA2785658C (en) | 2017-10-24 |
| EP2519108A4 (en) | 2013-10-16 |
| IL220613B (en) | 2018-06-28 |
| US9138441B2 (en) | 2015-09-22 |
| US20170246226A1 (en) | 2017-08-31 |
| WO2011082218A1 (en) | 2011-07-07 |
| US9649348B2 (en) | 2017-05-16 |
| AU2010339573A1 (en) | 2012-07-19 |
| US20170056456A1 (en) | 2017-03-02 |
| IL220613A0 (en) | 2012-08-30 |
| MX2012007735A (es) | 2012-09-28 |
| US20120276201A1 (en) | 2012-11-01 |
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