JP2016519124A5 - - Google Patents
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- JP2016519124A5 JP2016519124A5 JP2016511042A JP2016511042A JP2016519124A5 JP 2016519124 A5 JP2016519124 A5 JP 2016519124A5 JP 2016511042 A JP2016511042 A JP 2016511042A JP 2016511042 A JP2016511042 A JP 2016511042A JP 2016519124 A5 JP2016519124 A5 JP 2016519124A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- concentration
- seq
- antibody
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361816899P | 2013-04-29 | 2013-04-29 | |
| US61/816,899 | 2013-04-29 | ||
| EP14305160.5 | 2014-02-05 | ||
| EP14305160 | 2014-02-05 | ||
| PCT/EP2014/058733 WO2014177568A1 (en) | 2013-04-29 | 2014-04-29 | Anti-il-4/anti-il-13 bispecific antibody formulations |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019004836A Division JP2019070025A (ja) | 2013-04-29 | 2019-01-16 | 抗ｉｌ−４／抗ｉｌ−１３二特異的抗体製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016519124A JP2016519124A (ja) | 2016-06-30 |
| JP2016519124A5 true JP2016519124A5 (enExample) | 2017-06-22 |
| JP6470261B2 JP6470261B2 (ja) | 2019-02-13 |
Family
ID=50159179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016511042A Active JP6470261B2 (ja) | 2013-04-29 | 2014-04-29 | 抗ｉｌ−４／抗ｉｌ−１３二特異的抗体製剤 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US10005835B2 (enExample) |
| EP (1) | EP2991678B1 (enExample) |
| JP (1) | JP6470261B2 (enExample) |
| KR (1) | KR102307257B1 (enExample) |
| CN (1) | CN105339004B (enExample) |
| AU (1) | AU2014261497B2 (enExample) |
| CA (1) | CA2910693C (enExample) |
| CL (1) | CL2015003193A1 (enExample) |
| IL (1) | IL242372B2 (enExample) |
| MX (1) | MX378502B (enExample) |
| MY (1) | MY178837A (enExample) |
| PH (1) | PH12015502441B1 (enExample) |
| RU (1) | RU2690850C2 (enExample) |
| SG (2) | SG10201708746RA (enExample) |
| TW (1) | TWI679019B (enExample) |
| WO (1) | WO2014177568A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2050764A1 (en) | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| TWI719112B (zh) | 2011-03-16 | 2021-02-21 | 賽諾菲公司 | 雙重ｖ區類抗體蛋白質之用途 |
| BR112015027291A8 (pt) | 2013-05-03 | 2019-12-24 | Selecta Biosciences Inc | uso de um imunossupressor que têm uma vida eficaz farmacodinâmica especificada e composição compreendendo o referido imunossupressor |
| TWI745962B (zh) | 2014-06-27 | 2021-11-11 | 法商賽諾菲公司 | 測定投予至人類個體之包括雙-v-區類抗體蛋白或其片段的劑量是否在人類個體中與il-4或il-13特異性結合之方法 |
| KR101776879B1 (ko) * | 2015-01-19 | 2017-09-08 | 주식회사 녹십자 | 항-egfr 항체를 포함하는 약학 제제 |
| CN108778261A (zh) * | 2016-01-12 | 2018-11-09 | 雷迪博士实验室有限公司 | 稳定的药物组合物 |
| KR20240052871A (ko) | 2016-04-27 | 2024-04-23 | 애브비 인코포레이티드 | 항-il-13 항체를 이용한 il-13 활성이 유해한 질환의 치료 방법 |
| EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| US10940185B2 (en) | 2016-12-28 | 2021-03-09 | Jcr Pharmaceuticals Co., Ltd. | Lyophilized preparation |
| WO2018183932A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a il-13 inhibitor |
| US11603407B2 (en) * | 2017-04-06 | 2023-03-14 | Regeneron Pharmaceuticals, Inc. | Stable antibody formulation |
| HRP20240167T1 (hr) | 2017-04-28 | 2024-04-26 | Amgen Inc. | Formulacije ljudskih anti-rankl protutijela i postupci njihove upotrebe |
| WO2018211517A1 (en) | 2017-05-16 | 2018-11-22 | Bhami's Research Laboratory, Pvt. Ltd. | High concentration protein formulations with reduced viscosity |
| TWI795415B (zh) | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段 |
| WO2019221269A1 (ja) | 2018-05-17 | 2019-11-21 | アステラス製薬株式会社 | 抗ヒトＭＵＣ１抗体Ｆａｂフラグメント、ペプチドリンカー及び／又は配位子を含む複合体 |
| WO2020053301A1 (en) * | 2018-09-11 | 2020-03-19 | Ichnos Sciences S.A. | Compositions comprising a bispecific antibody, bufffer and one or more stabilizing agents |
| CN112789028A (zh) * | 2018-10-01 | 2021-05-11 | 美国安进公司 | 用于减少双特异性抗体的聚集的方法 |
| MY205764A (en) * | 2018-10-10 | 2024-11-12 | Astellas Pharma Inc | Pharmaceutical composition containing tagged site-antihuman antibody fab fragment complex |
| KR102131519B1 (ko) * | 2018-10-30 | 2020-07-07 | 가톨릭대학교 산학협력단 | 간암 전이 진단 또는 예후 예측용 바이오마커 및 이의 용도 |
| WO2020106757A1 (en) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| SG11202108627SA (en) | 2019-02-18 | 2021-09-29 | Lilly Co Eli | Therapeutic antibody formulation |
| JP7784898B2 (ja) * | 2019-05-24 | 2025-12-12 | サノフイ | 全身性硬化症を治療するための方法 |
| EP3980784A1 (en) | 2019-06-04 | 2022-04-13 | Selecta Biosciences, Inc. | Formulations and doses of pegylated uricase |
| GB201911461D0 (en) * | 2019-08-09 | 2019-09-25 | Arecor Ltd | Novel composition |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| AU2021236234A1 (en) * | 2020-03-11 | 2022-10-06 | Selecta Biosciences, Inc. | Methods and compositions related to synthetic nanocarriers |
| WO2026011751A1 (zh) * | 2024-07-08 | 2026-01-15 | 武汉友芝友生物制药股份有限公司 | 抗体制剂 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
| US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| ES2284161T3 (es) | 1990-01-12 | 2007-11-01 | Amgen Fremont Inc. | Generacion de anticuerpos xenogenicos. |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5869619A (en) | 1991-12-13 | 1999-02-09 | Xoma Corporation | Modified antibody variable domains |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| EP0822830B1 (en) | 1995-04-27 | 2008-04-02 | Amgen Fremont Inc. | Human anti-IL-8 antibodies, derived from immunized xenomice |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| ATE549918T1 (de) | 1996-12-03 | 2012-04-15 | Amgen Fremont Inc | Menschliche antikörper, die ausdrücklich menschliches tnf alpha binden |
| TR199902553T2 (xx) | 1997-04-14 | 2000-03-21 | Micromet Gesellschaft F�R Biomedizinische Forschung Mbh | �nsan v�cuduna kar�� antijen resept�rlerinin �retimi i�in yeni metod ve kullan�mlar�. |
| US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| US20040023338A1 (en) | 2001-10-26 | 2004-02-05 | Heavner George A. | IL-4 mutein proteins, antibodies, compositions, methods and uses |
| EP1578912A4 (en) | 2001-10-26 | 2007-12-26 | Centocor Inc | IL-13 MUTEIN PROTEINS, ANTIBODIES, COMPOSITIONS, METHODS AND USES |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| TWI307630B (en) * | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
| US20060148009A1 (en) | 2004-10-12 | 2006-07-06 | Xencor, Inc. | Prediction and assessment of immunogenicity |
| WO2008086395A2 (en) * | 2007-01-09 | 2008-07-17 | Wyeth | Anti-il-13 antibody formulations and uses thereof |
| EP2050764A1 (en) * | 2007-10-15 | 2009-04-22 | sanofi-aventis | Novel polyvalent bispecific antibody format and uses thereof |
| WO2009070642A1 (en) | 2007-11-28 | 2009-06-04 | Medimmune, Llc | Protein formulation |
| EP2196476A1 (en) | 2008-12-10 | 2010-06-16 | Novartis Ag | Antibody formulation |
| EP2458990B1 (en) * | 2009-07-28 | 2016-03-30 | Merck Sharp & Dohme Corp. | Methods for producing high concentration lyophilized pharmaceutical formulations |
| EP2547365A1 (en) * | 2010-03-17 | 2013-01-23 | Abbott Research B.V. | Anti-nerve growth factor (ngf) antibody compositions |
| TWI719112B (zh) * | 2011-03-16 | 2021-02-21 | 賽諾菲公司 | 雙重ｖ區類抗體蛋白質之用途 |
| TWI838039B (zh) | 2011-03-28 | 2024-04-01 | 法商賽諾菲公司 | 具有交叉結合區定向之雙重可變區類抗體結合蛋白 |
| JOP20200043A1 (ar) * | 2011-05-10 | 2017-06-16 | Amgen Inc | طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول |
| ES2806146T3 (es) * | 2011-09-22 | 2021-02-16 | Amgen Inc | Proteínas de unión al antígeno CD27L |
| CN102961745B (zh) * | 2012-09-27 | 2015-02-18 | 苏州康聚生物科技有限公司 | 抗体组合物制剂及其应用 |
-
2014
- 2014-04-25 TW TW103114922A patent/TWI679019B/zh active
- 2014-04-29 SG SG10201708746RA patent/SG10201708746RA/en unknown
- 2014-04-29 WO PCT/EP2014/058733 patent/WO2014177568A1/en not_active Ceased
- 2014-04-29 EP EP14724659.9A patent/EP2991678B1/en active Active
- 2014-04-29 SG SG11201508682RA patent/SG11201508682RA/en unknown
- 2014-04-29 US US14/787,507 patent/US10005835B2/en active Active
- 2014-04-29 AU AU2014261497A patent/AU2014261497B2/en active Active
- 2014-04-29 RU RU2015150149A patent/RU2690850C2/ru active
- 2014-04-29 MY MYPI2015703782A patent/MY178837A/en unknown
- 2014-04-29 JP JP2016511042A patent/JP6470261B2/ja active Active
- 2014-04-29 CN CN201480037173.9A patent/CN105339004B/zh active Active
- 2014-04-29 CA CA2910693A patent/CA2910693C/en active Active
- 2014-04-29 IL IL242372A patent/IL242372B2/en unknown
- 2014-04-29 MX MX2015015152A patent/MX378502B/es unknown
- 2014-04-29 KR KR1020157032914A patent/KR102307257B1/ko active Active
-
2015
- 2015-10-22 PH PH12015502441A patent/PH12015502441B1/en unknown
- 2015-10-29 CL CL2015003193A patent/CL2015003193A1/es unknown
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