|
HUP9801135A2
(hu)
|
1995-05-09 |
1998-08-28 |
Basf Aktiengesellschaft |
Pirazolo[1,5-a]pirimidinek, eljárás előállításukra és alkalmazásuk
|
|
US6060478A
(en)
|
1996-07-24 |
2000-05-09 |
Dupont Pharmaceuticals |
Azolo triazines and pyrimidines
|
|
US6191131B1
(en)
|
1997-07-23 |
2001-02-20 |
Dupont Pharmaceuticals Company |
Azolo triazines and pyrimidines
|
|
JPH10218881A
(ja)
|
1997-02-03 |
1998-08-18 |
Pola Chem Ind Inc |
新規なピロロピラゾロピリミジン誘導体
|
|
GB2323861B
(en)
|
1997-02-05 |
2001-06-20 |
Sector Exhibiting Systems |
Artificial wall structure
|
|
US6235741B1
(en)
|
1997-05-30 |
2001-05-22 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
JP2002501532A
(ja)
|
1997-05-30 |
2002-01-15 |
メルク エンド カンパニー インコーポレーテッド |
新規血管形成阻害薬
|
|
US6245759B1
(en)
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
JP2001302666A
(ja)
|
1999-09-21 |
2001-10-31 |
Nissan Chem Ind Ltd |
アゾール縮合ヘテロ環アニライド化合物及び除草剤
|
|
MY125533A
(en)
|
1999-12-06 |
2006-08-30 |
Bristol Myers Squibb Co |
Heterocyclic dihydropyrimidine compounds
|
|
US6723332B2
(en)
|
2000-05-26 |
2004-04-20 |
Neurogen Corporation |
Oxomidazopyridine-carboxamides
|
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
|
US7067520B2
(en)
|
2000-11-17 |
2006-06-27 |
Ishihara Sangyo Kaisha, Ltd. |
Preventive or therapeutic medicines for diabetes containing fused-heterocyclic compounds or their salts
|
|
GB0103926D0
(en)
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
|
EP1463742A4
(en)
|
2001-06-21 |
2006-05-10 |
Ariad Pharma Inc |
NEW PYRAZOLO AND PYRROLO PYRIMIDINES AND THEIR USES
|
|
US6833371B2
(en)
|
2001-11-01 |
2004-12-21 |
Icagen, Inc. |
Pyrazolopyrimidines
|
|
KR20040097375A
(ko)
*
|
2002-04-23 |
2004-11-17 |
시오노기 앤드 컴파니, 리미티드 |
피라졸로[1, 5-에이]피리미딘 유도체 및 이를 함유한엔에이디(피)에이취 산화효소 저해제
|
|
EP1511751B1
(en)
|
2002-06-04 |
2008-03-19 |
Neogenesis Pharmaceuticals, Inc. |
Pyrazolo[1,5-a]pyrimidine compounds as antiviral agents
|
|
US7449488B2
(en)
|
2002-06-04 |
2008-11-11 |
Schering Corporation |
Pyrazolopyrimidines as protein kinase inhibitors
|
|
CA2497544C
(en)
|
2002-09-04 |
2010-11-02 |
Schering Corporation |
Pyrazolo[1,5-a]pyrimidines compounds as cyclin dependent kinase inhibitors
|
|
MXPA05002571A
(es)
|
2002-09-04 |
2005-09-08 |
Schering Corp |
Pirazolopirimidinas como inhibidores de cinasa dependientes de ciclina.
|
|
US8580782B2
(en)
|
2002-09-04 |
2013-11-12 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
|
|
US7601724B2
(en)
|
2002-09-04 |
2009-10-13 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
US7119200B2
(en)
|
2002-09-04 |
2006-10-10 |
Schering Corporation |
Pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7196092B2
(en)
|
2002-09-04 |
2007-03-27 |
Schering Corporation |
N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7563798B2
(en)
|
2002-09-04 |
2009-07-21 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
MXPA05002570A
(es)
|
2002-09-04 |
2005-09-08 |
Schering Corp |
Pirazolopirimidinas como inhibidores de cinasa dependientes de ciclina.
|
|
US8673924B2
(en)
|
2002-09-04 |
2014-03-18 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
|
|
CN1310918C
(zh)
|
2002-09-04 |
2007-04-18 |
先灵公司 |
作为细胞周期蛋白依赖激酶抑制剂的吡唑并嘧啶
|
|
US7205308B2
(en)
|
2002-09-04 |
2007-04-17 |
Schering Corporation |
Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7196078B2
(en)
|
2002-09-04 |
2007-03-27 |
Schering Corpoartion |
Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
AU2003299651A1
(en)
|
2002-12-11 |
2004-06-30 |
Merck And Co., Inc. |
Tyrosine kinase inhibitors
|
|
KR20050115252A
(ko)
|
2003-02-28 |
2005-12-07 |
데이진 화-마 가부시키가이샤 |
피라졸로[1,5-a]피리미딘 유도체
|
|
NZ546611A
(en)
|
2003-09-18 |
2010-02-26 |
Conforma Therapeutics Corp |
Novel heterocyclic compounds as HSP90-inhibitors
|
|
NZ547481A
(en)
|
2003-11-19 |
2009-12-24 |
Array Biopharma Inc |
Heterocyclic inhibitors of mek and methods of use thereof
|
|
EP1720879A2
(de)
|
2004-02-25 |
2006-11-15 |
Basf Aktiengesellschaft |
Azolopyrimidin-verbindungen und ihre verwendung zur bekämpfung von schadpilzen
|
|
WO2005117909A2
(en)
|
2004-04-23 |
2005-12-15 |
Exelixis, Inc. |
Kinase modulators and methods of use
|
|
ES2354824T3
(es)
*
|
2004-11-04 |
2011-03-18 |
Vertex Pharmaceuticals, Inc. |
Pirazolo[1,5-a]pirimidinas útiles como inhibidores de proteínas cinasas.
|
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US20060156482A1
(en)
|
2005-01-14 |
2006-07-20 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
|
DE102005007534A1
(de)
|
2005-02-17 |
2006-08-31 |
Bayer Cropscience Ag |
Pyrazolopyrimidine
|
|
US20070155738A1
(en)
|
2005-05-20 |
2007-07-05 |
Alantos Pharmaceuticals, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
US20070155737A1
(en)
|
2005-05-20 |
2007-07-05 |
Alantos Pharmaceuticals, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
US20060293345A1
(en)
|
2005-05-20 |
2006-12-28 |
Christoph Steeneck |
Heterobicyclic metalloprotease inhibitors
|
|
CA2624882C
(en)
|
2005-10-06 |
2014-05-20 |
Schering Corporation |
Pyrazolopyrimidines as protein kinase inhibitors
|
|
US7642266B2
(en)
|
2005-10-06 |
2010-01-05 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
BRPI0616985B1
(pt)
|
2005-10-06 |
2021-10-26 |
Merck Sharp & Dohme Corp. |
Composto de pirazolo[1,5-a]pirimidina, e, uso de um composto
|
|
CN101316847A
(zh)
|
2005-10-06 |
2008-12-03 |
先灵公司 |
用作蛋白激酶抑制剂的吡唑并(1,5a)嘧啶化合物
|
|
KR101071438B1
(ko)
|
2005-10-21 |
2011-10-10 |
미쓰비시 타나베 파마 코퍼레이션 |
카나비노이드 수용체 길항제로서의피라졸로[1,5-a]피리미딘 화합물
|
|
WO2007048064A2
(en)
|
2005-10-21 |
2007-04-26 |
Exelixis, Inc. |
Amino-pyrimidines as casein kinase ii (ck2) modulators
|
|
EP2007373A4
(en)
|
2006-03-29 |
2012-12-19 |
Foldrx Pharmaceuticals Inc |
INHIBITION OF ALPHA SYNUCLEINE TOXICITY
|
|
KR20090019796A
(ko)
|
2006-05-22 |
2009-02-25 |
쉐링 코포레이션 |
CDK 억제제로서의 피라졸로[1,5-a]피리미딘
|
|
AR061793A1
(es)
|
2006-07-05 |
2008-09-24 |
Mitsubishi Tanabe Pharma Corp |
Compuesto de pirazolo[1,5-a] pirimidina y composicion farmaceutica
|
|
US8198448B2
(en)
|
2006-07-14 |
2012-06-12 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
PE20080403A1
(es)
|
2006-07-14 |
2008-04-25 |
Amgen Inc |
Derivados heterociclicos fusionados y metodos de uso
|
|
CA2670083A1
(en)
|
2006-11-20 |
2008-05-29 |
Alantos Pharmaceuticals Holding, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
EP2014661A1
(de)
|
2007-06-13 |
2009-01-14 |
Bayer CropScience AG |
Heterocyclisch substituierte Heterocyclyl-carbonsäurederivate
|
|
US20090012103A1
(en)
|
2007-07-05 |
2009-01-08 |
Matthew Abelman |
Substituted heterocyclic compounds
|
|
WO2009006580A1
(en)
|
2007-07-05 |
2009-01-08 |
Cv Therapeutics, Inc. |
Optionally condensed dihydropyridine, dihydropyrimidine and dihydropyrane derivatives acting as late sodium channel blockers
|
|
WO2009017954A1
(en)
|
2007-08-01 |
2009-02-05 |
Phenomix Corporation |
Inhibitors of jak2 kinase
|
|
CA2706946A1
(en)
|
2007-11-28 |
2009-06-04 |
Schering Corporation |
2-fluoropyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
WO2009075790A1
(en)
|
2007-12-07 |
2009-06-18 |
Alantos Pharmaceuticals Holding, Inc. |
Metalloprotease inhibitors for intra-articular application
|
|
CA2711558C
(en)
|
2008-01-04 |
2016-12-13 |
Intellikine, Inc. |
Phosphatidyl inositol-3 kinase inhibiting compounds
|
|
EP2085398A1
(en)
|
2008-02-01 |
2009-08-05 |
Merz Pharma GmbH & Co. KGaA |
Pyrazolopyrimidines, a process for their preparation and their use as medicine
|
|
JP2011515401A
(ja)
|
2008-03-20 |
2011-05-19 |
アムジエン・インコーポレーテツド |
オーロラキナーゼモジュレーターおよび使用方法
|
|
AU2009268611B2
(en)
|
2008-07-08 |
2015-04-09 |
Intellikine, Llc |
Kinase inhibitors and methods of use
|
|
EP2320907A4
(en)
|
2008-08-05 |
2012-09-05 |
Merck Sharp & Dohme |
THERAPEUTIC COMPOUNDS
|
|
WO2010034738A2
(en)
|
2008-09-24 |
2010-04-01 |
Basf Se |
Pyrazole compounds for controlling invertebrate pests
|
|
CN102271515B
(zh)
|
2008-10-31 |
2014-07-02 |
健泰科生物技术公司 |
吡唑并嘧啶jak抑制剂化合物和方法
|
|
WO2010059836A1
(en)
|
2008-11-20 |
2010-05-27 |
Decode Genetics Ehf |
Substituted aza-bridged bicyclics for cardiovascular and cns disease
|
|
WO2010086040A1
(en)
|
2009-01-29 |
2010-08-05 |
Biomarin Iga, Ltd. |
Pyrazolo-pyrimidines for treatment of duchenne muscular dystrophy
|
|
US20100204265A1
(en)
|
2009-02-09 |
2010-08-12 |
Genelabs Technologies, Inc. |
Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections
|
|
CN101537007A
(zh)
|
2009-03-18 |
2009-09-23 |
中国医学科学院血液病医院(血液学研究所) |
N-(噻吩-2)吡唑并[1,5-a]嘧啶-3-甲酰胺类化合物在制备抗恶性肿瘤药物方面的应用
|
|
UA110324C2
(en)
|
2009-07-02 |
2015-12-25 |
Genentech Inc |
Jak inhibitory compounds based on pyrazolo pyrimidine
|
|
MY162604A
(en)
|
2009-08-17 |
2017-06-30 |
Intellikine Llc |
Heterocyclic compounds and uses thereof
|
|
CN101671336B
(zh)
|
2009-09-23 |
2013-11-13 |
辽宁利锋科技开发有限公司 |
芳杂环并嘧啶衍生物和类似物及其制备方法和用途
|
|
RU2607453C2
(ru)
|
2009-12-04 |
2017-01-10 |
Сенхва Байосайенсиз, Инк. |
Пиразолопиримидины и родственные гетероциклы как ск2 ингибиторы
|
|
ES2572387T3
(es)
|
2010-03-18 |
2016-05-31 |
Pasteur Institut Korea |
Compuestos anti-infecciosos
|
|
WO2011121096A1
(en)
|
2010-03-31 |
2011-10-06 |
Dkfz Deutsches Krebsforschungszentrum |
PYRAZOL[1,5-a]PYRIMIDINE DERIVATIVES AS WNT PATHWAY ANTAGONISTS
|
|
WO2011163527A1
(en)
|
2010-06-23 |
2011-12-29 |
Vertex Pharmaceuticals Incorporated |
Pyrrolo- pyrazine derivatives useful as inhibitors of atr kinase
|
|
MX2012015292A
(es)
|
2010-06-24 |
2013-05-30 |
Gilead Sciences Inc |
Pirazolo[1, 5]pirimidinas en la forma de agentes antivirales.
|
|
CN102985426B
(zh)
|
2010-07-13 |
2015-10-07 |
弗·哈夫曼-拉罗切有限公司 |
作为irak4调节剂的吡唑并[1,5a]嘧啶和噻吩并[3,2b]嘧啶衍生物
|
|
WO2012022045A1
(en)
|
2010-08-20 |
2012-02-23 |
Hutchison Medipharma Limited |
Pyrrolopyrimidine compounds and uses thereof
|
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
|
WO2012067822A1
(en)
|
2010-11-16 |
2012-05-24 |
Abbott Laboratories |
Pyrazolo [1, 5 -a] pyrimidin potassium channel modulators
|
|
CA2820362C
(en)
|
2010-12-08 |
2020-03-24 |
The United States Of America, As Represented By The Secretary, Departmt Of Health And Human Services |
Substituted pyrazolopyrimidines as glucocerebrosidase activators
|
|
JP6005134B2
(ja)
|
2011-04-21 |
2016-10-12 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
フルオロアルキル置換ピラゾロピリジンおよびその使用
|
|
WO2012143796A2
(en)
|
2011-04-21 |
2012-10-26 |
Institut Pasteur Korea |
Anti-inflammation compounds
|
|
JP2014522818A
(ja)
|
2011-06-22 |
2014-09-08 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Atrキナーゼ阻害剤として有用な化合物
|
|
US9845327B2
(en)
|
2011-06-22 |
2017-12-19 |
The General Hospital Corporation |
Treatment of proteinopathies
|
|
JP2014517079A
(ja)
|
2011-06-22 |
2014-07-17 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Atrキナーゼ阻害剤として有用な化合物
|
|
EP2723745A1
(en)
|
2011-06-22 |
2014-04-30 |
Vertex Pharmaceuticals Inc. |
Compounds useful as inhibitors of atr kinase
|
|
EA201490265A1
(ru)
|
2011-07-13 |
2014-12-30 |
Фармасайкликс, Инк. |
Ингибиторы тирозинкиназы брутона
|
|
WO2013052263A2
(en)
|
2011-09-16 |
2013-04-11 |
Microbiotix, Inc. |
Antifungal compounds
|
|
WO2013138436A1
(en)
|
2012-03-14 |
2013-09-19 |
Bristol-Myers Squibb Company |
Cyclolic hydrazine derivatives as hiv attachment inhibitors
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
BR112014024552A2
(pt)
|
2012-04-02 |
2017-09-19 |
Cytokinetics Inc |
método para aprimorar a função do diafragma em um paciente que necessite do mesmo; método para aumentar a função, atividade, eficiência, sensibilidade ao cálcio ou tempo de fadiga do músculo esquelético no diafragma de um paciente que necessite do mesmo e método para aumentar a função, atividade, eficiência, força, sensibilidade ao cálcio ou tempo de fadiga de uma fibra muscular esquelética do diafragma.
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
CN103373996A
(zh)
|
2012-04-20 |
2013-10-30 |
山东亨利医药科技有限责任公司 |
作为crth2受体拮抗剂的二并环衍生物
|
|
KR20150014506A
(ko)
|
2012-05-23 |
2015-02-06 |
사피라 파르마슈티칼즈 게엠베하 |
바이러스성 질환의 치료, 개선 또는 예방에서 유용한 7-옥소-4,7-디하이드로-피라졸로[1,5-a]피리미딘 유도체
|
|
EP2864338B1
(en)
|
2012-05-23 |
2016-12-14 |
Savira Pharmaceuticals GmbH |
7-oxo-thiazolopyridine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease
|
|
WO2014011911A2
(en)
|
2012-07-11 |
2014-01-16 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
WO2014015523A1
(en)
|
2012-07-27 |
2014-01-30 |
Hutchison Medipharma Limited |
Novel heteroaryl and heterocycle compounds, compositions and methods
|
|
KR20150039832A
(ko)
|
2012-08-06 |
2015-04-13 |
사피라 파르마슈티칼즈 게엠베하 |
디하이드록시피리미딘 탄산 유도체 및 바이러스성 질환의 치료, 개선 또는 예방에서의 이의 용도
|
|
US9505752B2
(en)
|
2012-08-09 |
2016-11-29 |
Viiv Healthcare Uk (No. 5) Limited |
Piperidine amide derivatives as HIV attachment inhibitors
|
|
EP2895472B1
(en)
|
2012-08-09 |
2016-11-23 |
VIIV Healthcare UK (No.5) Limited |
Tricyclic alkene derivatives as HIV attachment inhibitors
|
|
WO2014025850A1
(en)
|
2012-08-09 |
2014-02-13 |
Bristol-Myers Squibb Company |
Tricyclic amidine derivatives as hiv attachment inhibitors
|
|
US9345247B2
(en)
|
2012-08-17 |
2016-05-24 |
Bayer Cropscience Ag |
Azaindole carboxylic acid amides and azaindole thiocarboxylic acid amides for use as insecticides and acaricides
|
|
CN104583197B
(zh)
|
2012-08-24 |
2017-05-17 |
霍夫曼-拉罗奇有限公司 |
新型双环吡啶衍生物
|
|
WO2014035140A2
(en)
|
2012-08-30 |
2014-03-06 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating histone methyltransferase activity
|
|
WO2014039831A1
(en)
|
2012-09-07 |
2014-03-13 |
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
|
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(ja)
|
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|
|
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|
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|