|
DE59608203D1
(de)
|
1995-05-09 |
2001-12-20 |
Basf Ag |
PYRAZOLO- 1,5a]-PYRIMIDINE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
|
|
US6191131B1
(en)
|
1997-07-23 |
2001-02-20 |
Dupont Pharmaceuticals Company |
Azolo triazines and pyrimidines
|
|
US6060478A
(en)
|
1996-07-24 |
2000-05-09 |
Dupont Pharmaceuticals |
Azolo triazines and pyrimidines
|
|
JPH10218881A
(ja)
|
1997-02-03 |
1998-08-18 |
Pola Chem Ind Inc |
新規なピロロピラゾロピリミジン誘導体
|
|
GB2323861B
(en)
|
1997-02-05 |
2001-06-20 |
Sector Exhibiting Systems |
Artificial wall structure
|
|
AU734009B2
(en)
|
1997-05-30 |
2001-05-31 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
US6235741B1
(en)
|
1997-05-30 |
2001-05-22 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
US6245759B1
(en)
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
JP2001302666A
(ja)
|
1999-09-21 |
2001-10-31 |
Nissan Chem Ind Ltd |
アゾール縮合ヘテロ環アニライド化合物及び除草剤
|
|
MY125533A
(en)
|
1999-12-06 |
2006-08-30 |
Bristol Myers Squibb Co |
Heterocyclic dihydropyrimidine compounds
|
|
US6723332B2
(en)
|
2000-05-26 |
2004-04-20 |
Neurogen Corporation |
Oxomidazopyridine-carboxamides
|
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
|
US7067520B2
(en)
|
2000-11-17 |
2006-06-27 |
Ishihara Sangyo Kaisha, Ltd. |
Preventive or therapeutic medicines for diabetes containing fused-heterocyclic compounds or their salts
|
|
GB0103926D0
(en)
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
|
EP1463742A4
(en)
|
2001-06-21 |
2006-05-10 |
Ariad Pharma Inc |
NEW PYRAZOLO AND PYRROLO PYRIMIDINES AND THEIR USES
|
|
WO2003037900A2
(en)
|
2001-11-01 |
2003-05-08 |
Icagen, Inc. |
Pyrazolopyrimidines
|
|
US7662826B2
(en)
*
|
2002-04-23 |
2010-02-16 |
Shionogi & Co., Ltd. |
Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same
|
|
US7449488B2
(en)
|
2002-06-04 |
2008-11-11 |
Schering Corporation |
Pyrazolopyrimidines as protein kinase inhibitors
|
|
AU2003240488A1
(en)
|
2002-06-04 |
2003-12-19 |
Neogenesis Pharmaceuticals, Inc. |
Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents
|
|
US7205308B2
(en)
|
2002-09-04 |
2007-04-17 |
Schering Corporation |
Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
WO2004022559A1
(en)
|
2002-09-04 |
2004-03-18 |
Schering Corporation |
Pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7196092B2
(en)
|
2002-09-04 |
2007-03-27 |
Schering Corporation |
N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7196078B2
(en)
|
2002-09-04 |
2007-03-27 |
Schering Corpoartion |
Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7563798B2
(en)
|
2002-09-04 |
2009-07-21 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
TWI335919B
(en)
|
2002-09-04 |
2011-01-11 |
Schering Corp |
Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US8580782B2
(en)
|
2002-09-04 |
2013-11-12 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
|
|
US7601724B2
(en)
|
2002-09-04 |
2009-10-13 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
EP1537116B1
(en)
|
2002-09-04 |
2010-06-02 |
Schering Corporation |
Pyrazolopyrimidines suitable for the treatment of cancer diseases
|
|
US7119200B2
(en)
|
2002-09-04 |
2006-10-10 |
Schering Corporation |
Pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US8673924B2
(en)
|
2002-09-04 |
2014-03-18 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
|
|
CN1701073B
(zh)
|
2002-09-04 |
2011-06-22 |
先灵公司 |
作为细胞周期蛋白依赖激酶抑制剂的吡唑并[1,5-a]嘧啶
|
|
WO2004052315A2
(en)
|
2002-12-11 |
2004-06-24 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
EP1599482A4
(en)
|
2003-02-28 |
2008-10-01 |
Teijin Pharma Ltd |
PYRAZOLO1,5-A PYRIMIDINE DERIVATIVES
|
|
EP2145888A1
(en)
|
2003-09-18 |
2010-01-20 |
Conforma Therapeutics Corporation |
Deazapurine derivatives as HSP90-Inhibitors
|
|
CN1905873A
(zh)
|
2003-11-19 |
2007-01-31 |
阵列生物制药公司 |
Mek的杂环抑制剂及其使用方法
|
|
EP1720879A2
(de)
|
2004-02-25 |
2006-11-15 |
Basf Aktiengesellschaft |
Azolopyrimidin-verbindungen und ihre verwendung zur bekämpfung von schadpilzen
|
|
JP5213229B2
(ja)
|
2004-04-23 |
2013-06-19 |
エグゼリクシス， インコーポレイテッド |
キナーゼ調節因子および使用方法
|
|
EP1812440B1
(en)
*
|
2004-11-04 |
2010-09-22 |
Vertex Pharmaceuticals, Inc. |
Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases
|
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US20060156482A1
(en)
|
2005-01-14 |
2006-07-20 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
|
DE102005007534A1
(de)
|
2005-02-17 |
2006-08-31 |
Bayer Cropscience Ag |
Pyrazolopyrimidine
|
|
EA013525B1
(ru)
|
2005-05-20 |
2010-06-30 |
Алантос-Фармасьютикалз Холдинг, Инк. |
Гетеробициклические ингибиторы металлопротеазы и их применение
|
|
US20070155737A1
(en)
|
2005-05-20 |
2007-07-05 |
Alantos Pharmaceuticals, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
US20070155738A1
(en)
|
2005-05-20 |
2007-07-05 |
Alantos Pharmaceuticals, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
AR057979A1
(es)
|
2005-10-06 |
2008-01-09 |
Schering Corp |
PIRAZOLPIRIMIDINAS COMO INHIBIDORAS DE PROTEíNA QUINASA. COMPOSICIONES FARMACEUTICAS.
|
|
US7776865B2
(en)
|
2005-10-06 |
2010-08-17 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
WO2007044426A2
(en)
|
2005-10-06 |
2007-04-19 |
Schering Corporation |
Pyrazolopyrimidines as protein kinase inhibitors
|
|
CN101360499B
(zh)
|
2005-10-06 |
2015-10-07 |
默沙东公司 |
吡唑并[1,5-a]嘧啶衍生物在制备抑制蛋白激酶的药物中的用途
|
|
JP5119157B2
(ja)
|
2005-10-21 |
2013-01-16 |
エクセリクシス， インク． |
カゼインキナーゼｉｉ（ｃｋ２）モジュレーターとしてのピラゾロ−ピリミジン類
|
|
EP1945220A1
(en)
|
2005-10-21 |
2008-07-23 |
Mitsubishi Tanabe Pharma Corporation |
Pyrazolo[1,5-a]pyrimidine compounds as cannabinoid receptor antagonists
|
|
JP2009531443A
(ja)
|
2006-03-29 |
2009-09-03 |
フォールドアールエックス ファーマシューティカルズ インコーポレーティッド |
α−シヌクレイン毒性の抑制
|
|
KR20090019796A
(ko)
|
2006-05-22 |
2009-02-25 |
쉐링 코포레이션 |
ＣＤＫ 억제제로서의 피라졸로[1,5-ａ]피리미딘
|
|
AR061793A1
(es)
|
2006-07-05 |
2008-09-24 |
Mitsubishi Tanabe Pharma Corp |
Compuesto de pirazolo[1,5-a] pirimidina y composicion farmaceutica
|
|
US8198448B2
(en)
|
2006-07-14 |
2012-06-12 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
PE20080403A1
(es)
|
2006-07-14 |
2008-04-25 |
Amgen Inc |
Derivados heterociclicos fusionados y metodos de uso
|
|
CA2670083A1
(en)
|
2006-11-20 |
2008-05-29 |
Alantos Pharmaceuticals Holding, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
EP2014661A1
(de)
|
2007-06-13 |
2009-01-14 |
Bayer CropScience AG |
Heterocyclisch substituierte Heterocyclyl-carbonsäurederivate
|
|
WO2009006580A1
(en)
|
2007-07-05 |
2009-01-08 |
Cv Therapeutics, Inc. |
Optionally condensed dihydropyridine, dihydropyrimidine and dihydropyrane derivatives acting as late sodium channel blockers
|
|
US20090012103A1
(en)
|
2007-07-05 |
2009-01-08 |
Matthew Abelman |
Substituted heterocyclic compounds
|
|
WO2009017954A1
(en)
|
2007-08-01 |
2009-02-05 |
Phenomix Corporation |
Inhibitors of jak2 kinase
|
|
WO2009070567A1
(en)
|
2007-11-28 |
2009-06-04 |
Schering Corporation |
2-fluoropyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
WO2009075790A1
(en)
|
2007-12-07 |
2009-06-18 |
Alantos Pharmaceuticals Holding, Inc. |
Metalloprotease inhibitors for intra-articular application
|
|
AU2009204483B2
(en)
|
2008-01-04 |
2014-03-13 |
Intellikine, Llc |
Certain chemical entities, compositions and methods
|
|
EP2085398A1
(en)
|
2008-02-01 |
2009-08-05 |
Merz Pharma GmbH & Co. KGaA |
Pyrazolopyrimidines, a process for their preparation and their use as medicine
|
|
WO2009117157A1
(en)
|
2008-03-20 |
2009-09-24 |
Amgen Inc. |
Aurora kinase modulators and method of use
|
|
MX2011000216A
(es)
|
2008-07-08 |
2011-03-29 |
Intellikine Inc |
Inhibidores de cinasa y metodos para su uso.
|
|
WO2010017047A1
(en)
|
2008-08-05 |
2010-02-11 |
Merck & Co., Inc. |
Therapeutic compounds
|
|
CN102223798A
(zh)
|
2008-09-24 |
2011-10-19 |
巴斯夫欧洲公司 |
用于防治无脊椎动物害虫的吡唑化合物
|
|
RU2539568C2
(ru)
|
2008-10-31 |
2015-01-20 |
Дженентек, Инк. |
Пиразолопиримидиновые соединения-ингибиторы jak и способы
|
|
WO2010059836A1
(en)
|
2008-11-20 |
2010-05-27 |
Decode Genetics Ehf |
Substituted aza-bridged bicyclics for cardiovascular and cns disease
|
|
WO2010086040A1
(en)
|
2009-01-29 |
2010-08-05 |
Biomarin Iga, Ltd. |
Pyrazolo-pyrimidines for treatment of duchenne muscular dystrophy
|
|
US20100204265A1
(en)
|
2009-02-09 |
2010-08-12 |
Genelabs Technologies, Inc. |
Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections
|
|
CN101537007A
(zh)
|
2009-03-18 |
2009-09-23 |
中国医学科学院血液病医院（血液学研究所） |
N-(噻吩-2)吡唑并[1,5-a]嘧啶-3-甲酰胺类化合物在制备抗恶性肿瘤药物方面的应用
|
|
UA110324C2
(en)
|
2009-07-02 |
2015-12-25 |
Genentech Inc |
Jak inhibitory compounds based on pyrazolo pyrimidine
|
|
GEP201706639B
(en)
|
2009-08-17 |
2017-03-27 |
Intellikine Llc |
Heterocyclic compounds and uses thereof
|
|
CN101671336B
(zh)
|
2009-09-23 |
2013-11-13 |
辽宁利锋科技开发有限公司 |
芳杂环并嘧啶衍生物和类似物及其制备方法和用途
|
|
KR101851130B1
(ko)
|
2009-12-04 |
2018-04-23 |
센화 바이오사이언시즈 인코포레이티드 |
Ｃｋ2 억제제로서 피라졸로피리미딘 및 관련된 헤테로사이클
|
|
ES2572387T3
(es)
|
2010-03-18 |
2016-05-31 |
Pasteur Institut Korea |
Compuestos anti-infecciosos
|
|
WO2011121096A1
(en)
|
2010-03-31 |
2011-10-06 |
Dkfz Deutsches Krebsforschungszentrum |
PYRAZOL[1,5-a]PYRIMIDINE DERIVATIVES AS WNT PATHWAY ANTAGONISTS
|
|
EP2585468A1
(en)
|
2010-06-23 |
2013-05-01 |
Vertex Pharmaceuticals Incorporated |
Pyrrolo- pyrazine derivatives useful as inhibitors of atr kinase
|
|
RS54761B1
(sr)
|
2010-06-24 |
2016-10-31 |
Gilead Sciences |
Pirazolo[1,5-a]pirimidini i-triazini kao antiviralni agensi
|
|
KR101995013B1
(ko)
|
2010-07-13 |
2019-07-02 |
에프. 호프만-라 로슈 아게 |
Irak4 조절제로서 피라졸로[1,5a]피리미딘 및 티에노[3,2b]피리미딘 유도체
|
|
WO2012022045A1
(en)
|
2010-08-20 |
2012-02-23 |
Hutchison Medipharma Limited |
Pyrrolopyrimidine compounds and uses thereof
|
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
|
US8609669B2
(en)
|
2010-11-16 |
2013-12-17 |
Abbvie Inc. |
Potassium channel modulators
|
|
EP2649075B1
(en)
|
2010-12-08 |
2018-04-25 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Substituted pyrazolopyrimidines as glucocerebrosidase activators
|
|
ES2583086T3
(es)
|
2011-04-21 |
2016-09-19 |
Bayer Intellectual Property Gmbh |
Pirazolopiridinas sustituidas con fluoroalquilo y su uso
|
|
KR102104125B1
(ko)
|
2011-04-21 |
2020-05-29 |
재단법인 한국파스퇴르연구소 |
소염 화합물
|
|
EP2723747A1
(en)
|
2011-06-22 |
2014-04-30 |
Vertex Pharmaceuticals Inc. |
Compounds useful as inhibitors of atr kinase
|
|
WO2012178123A1
(en)
|
2011-06-22 |
2012-12-27 |
Vertex Pharmaceuticals Incorporated |
Compounds useful as inhibitors of atr kinase
|
|
CN103764166B
(zh)
|
2011-06-22 |
2017-10-24 |
通用医疗公司 |
蛋白质病的治疗
|
|
US9309250B2
(en)
|
2011-06-22 |
2016-04-12 |
Vertex Pharmaceuticals Incorporated |
Substituted pyrrolo[2,3-b]pyrazines as ATR kinase inhibitors
|
|
BR112014000653A2
(pt)
|
2011-07-13 |
2017-02-14 |
Pharmacyclics Inc |
inibidores de tirosina quinase de bruton
|
|
WO2013052263A2
(en)
|
2011-09-16 |
2013-04-11 |
Microbiotix, Inc. |
Antifungal compounds
|
|
WO2013138436A1
(en)
|
2012-03-14 |
2013-09-19 |
Bristol-Myers Squibb Company |
Cyclolic hydrazine derivatives as hiv attachment inhibitors
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
AU2013243671B2
(en)
|
2012-04-02 |
2017-09-21 |
Cytokinetics, Inc. |
Methods for improving diaphragm function
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
CN103373996A
(zh)
|
2012-04-20 |
2013-10-30 |
山东亨利医药科技有限责任公司 |
作为crth2受体拮抗剂的二并环衍生物
|
|
HK1204987A1
(en)
|
2012-05-23 |
2015-12-11 |
Savira Pharmaceuticals Gmbh |
7-oxo-4,7 -dihydro- pyrazolo [1, 5 -a]pyrimidine derivatives which are useful in the treatment, amelioration or prevention of a viral disease
|
|
CN104334563B
(zh)
|
2012-05-23 |
2017-03-08 |
萨维拉制药有限公司 |
7‑氧代‑噻唑并吡啶碳酸衍生物和它们在治疗、改善或预防病毒疾病中的用途
|
|
US20140018361A1
(en)
|
2012-07-11 |
2014-01-16 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
WO2014015523A1
(en)
|
2012-07-27 |
2014-01-30 |
Hutchison Medipharma Limited |
Novel heteroaryl and heterocycle compounds, compositions and methods
|
|
CA2879245A1
(en)
|
2012-08-06 |
2014-02-13 |
Savira Pharmaceuticals Gmbh |
Dihydroxypyrimidine carbonic acid derivatives and their use in the treatment, amelioration or prevention of a viral disease
|
|
WO2014025852A1
(en)
|
2012-08-09 |
2014-02-13 |
Bristol-Myers Squibb Company |
Tricyclic alkene derivatives as hiv attachment inhibitors
|
|
WO2014025850A1
(en)
|
2012-08-09 |
2014-02-13 |
Bristol-Myers Squibb Company |
Tricyclic amidine derivatives as hiv attachment inhibitors
|
|
US9505752B2
(en)
|
2012-08-09 |
2016-11-29 |
Viiv Healthcare Uk (No. 5) Limited |
Piperidine amide derivatives as HIV attachment inhibitors
|
|
KR20150044895A
(ko)
|
2012-08-17 |
2015-04-27 |
바이엘 크롭사이언스 아게 |
살곤충제 및 살응애제로서의 아자인돌 카르복실산 아미드 및 아자인돌 티오카르복실산 아미드
|
|
MX2015001099A
(es)
|
2012-08-24 |
2015-04-08 |
Hoffmann La Roche |
Nuevos derivados biciclicos de piridina.
|
|
WO2014035140A2
(en)
|
2012-08-30 |
2014-03-06 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating histone methyltransferase activity
|
|
WO2014039831A1
(en)
|
2012-09-07 |
2014-03-13 |
Takeda Pharmaceutical Company Limited |
SUBSTITUTED-1,4-DIHYDROPYRAZOLO[4,3-b]INDOLES
|
|
WO2014042433A2
(en)
|
2012-09-14 |
2014-03-20 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating adenosine a3 receptor activity
|
|
TW201412740A
(zh)
|
2012-09-20 |
2014-04-01 |
Bayer Pharma AG |
經取代之吡咯并嘧啶胺基苯并噻唑酮
|
|
CN104812389B
(zh)
|
2012-09-24 |
2020-07-17 |
润新生物公司 |
某些化学实体、组合物及方法
|
|
CA2900335C
(en)
|
2012-10-22 |
2021-10-26 |
City Of Hope |
Synthetic analogs of epipolythiodioxopiperazines and uses thereof
|
|
US9012643B2
(en)
|
2012-10-24 |
2015-04-21 |
Becton, Dickinson And Company |
Hydroxamate substituted azaindoline-cyanine dyes and bioconjugates of the same
|
|
WO2014089379A1
(en)
|
2012-12-07 |
2014-06-12 |
Vertex Pharmaceuticals Incorporated |
Compounds useful as inhibitors of atr kinase
|