|
DE59608203D1
(de)
|
1995-05-09 |
2001-12-20 |
Basf Ag |
PYRAZOLO- 1,5a]-PYRIMIDINE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
|
|
US6060478A
(en)
|
1996-07-24 |
2000-05-09 |
Dupont Pharmaceuticals |
Azolo triazines and pyrimidines
|
|
US6191131B1
(en)
|
1997-07-23 |
2001-02-20 |
Dupont Pharmaceuticals Company |
Azolo triazines and pyrimidines
|
|
JPH10218881A
(ja)
|
1997-02-03 |
1998-08-18 |
Pola Chem Ind Inc |
新規なピロロピラゾロピリミジン誘導体
|
|
GB2323861B
(en)
|
1997-02-05 |
2001-06-20 |
Sector Exhibiting Systems |
Artificial wall structure
|
|
CA2291709A1
(en)
|
1997-05-30 |
1998-12-03 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
US6235741B1
(en)
|
1997-05-30 |
2001-05-22 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
US6245759B1
(en)
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
JP2001302666A
(ja)
|
1999-09-21 |
2001-10-31 |
Nissan Chem Ind Ltd |
アゾール縮合ヘテロ環アニライド化合物及び除草剤
|
|
MY125533A
(en)
|
1999-12-06 |
2006-08-30 |
Bristol Myers Squibb Co |
Heterocyclic dihydropyrimidine compounds
|
|
AU2001264932A1
(en)
|
2000-05-26 |
2001-12-11 |
Neurogen Corporation |
Oxo-imidazopyrimidine-carboxamides and their use as gaba brain receptor ligands
|
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
|
US7067520B2
(en)
|
2000-11-17 |
2006-06-27 |
Ishihara Sangyo Kaisha, Ltd. |
Preventive or therapeutic medicines for diabetes containing fused-heterocyclic compounds or their salts
|
|
GB0103926D0
(en)
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
|
WO2003000187A2
(en)
|
2001-06-21 |
2003-01-03 |
Ariad Pharmaceuticals, Inc. |
Novel pyrazolo-and pyrrolo-pyrimidines and uses thereof
|
|
WO2003037900A2
(en)
|
2001-11-01 |
2003-05-08 |
Icagen, Inc. |
Pyrazolopyrimidines
|
|
US7662826B2
(en)
*
|
2002-04-23 |
2010-02-16 |
Shionogi & Co., Ltd. |
Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same
|
|
CA2487211C
(en)
|
2002-06-04 |
2010-09-14 |
Neogenesis Pharmaceuticals, Inc. |
Pyrazolo(1,5a) pyrimidine compounds as antiviral agents
|
|
US7449488B2
(en)
|
2002-06-04 |
2008-11-11 |
Schering Corporation |
Pyrazolopyrimidines as protein kinase inhibitors
|
|
JP4790265B2
(ja)
|
2002-09-04 |
2011-10-12 |
シェーリング コーポレイション |
サイクリン依存性キナーゼインヒビターとしての新規ピラゾロピリミジン
|
|
US7074924B2
(en)
|
2002-09-04 |
2006-07-11 |
Schering Corporation |
Pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
TW200413377A
(en)
|
2002-09-04 |
2004-08-01 |
Schering Corp |
Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7205308B2
(en)
|
2002-09-04 |
2007-04-17 |
Schering Corporation |
Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7196078B2
(en)
|
2002-09-04 |
2007-03-27 |
Schering Corpoartion |
Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7563798B2
(en)
|
2002-09-04 |
2009-07-21 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
US8580782B2
(en)
|
2002-09-04 |
2013-11-12 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
|
|
US7119200B2
(en)
|
2002-09-04 |
2006-10-10 |
Schering Corporation |
Pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
ATE469903T1
(de)
|
2002-09-04 |
2010-06-15 |
Schering Corp |
Zur behandlung von krebserkrankungen geeignete pyrazolopyrimidine
|
|
US8673924B2
(en)
|
2002-09-04 |
2014-03-18 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
|
|
US7196092B2
(en)
|
2002-09-04 |
2007-03-27 |
Schering Corporation |
N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors
|
|
US7601724B2
(en)
|
2002-09-04 |
2009-10-13 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
WO2004052315A2
(en)
|
2002-12-11 |
2004-06-24 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
JP4564485B2
(ja)
|
2003-02-28 |
2010-10-20 |
帝人ファーマ株式会社 |
ピラゾロ[1,5−a]ピリミジン誘導体
|
|
EA010160B1
(ru)
|
2003-09-18 |
2008-06-30 |
Конформа Терапьютикс Корпорейшн |
Новые гетероциклические соединения - ингибиторы hsp90 и способы их получения
|
|
ZA200604580B
(en)
|
2003-11-19 |
2009-08-26 |
Array Biopharma Inc |
Heterocyclic inhibitors of Mek and methods of use thereof
|
|
JP2007523939A
(ja)
|
2004-02-25 |
2007-08-23 |
ビーエーエスエフ アクチェンゲゼルシャフト |
アゾロピリミジン化合物及び寄生性菌類を駆除するためのその使用
|
|
WO2005117909A2
(en)
|
2004-04-23 |
2005-12-15 |
Exelixis, Inc. |
Kinase modulators and methods of use
|
|
US7528138B2
(en)
|
2004-11-04 |
2009-05-05 |
Vertex Pharmaceuticals Incorporated |
Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases
|
|
US7635699B2
(en)
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US20060156482A1
(en)
|
2005-01-14 |
2006-07-20 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
|
DE102005007534A1
(de)
|
2005-02-17 |
2006-08-31 |
Bayer Cropscience Ag |
Pyrazolopyrimidine
|
|
US20070155738A1
(en)
|
2005-05-20 |
2007-07-05 |
Alantos Pharmaceuticals, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
US20070155737A1
(en)
|
2005-05-20 |
2007-07-05 |
Alantos Pharmaceuticals, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
KR20080087070A
(ko)
|
2005-05-20 |
2008-09-30 |
알란토스 파마슈티컬즈 홀딩, 인코포레이티드 |
피리미딘 또는 트리아진 융합된 비시클릭 메탈로프로테아제억제제
|
|
US7642266B2
(en)
|
2005-10-06 |
2010-01-05 |
Schering Corporation |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
US7645762B2
(en)
*
|
2005-10-06 |
2010-01-12 |
Schering Corporation |
Substituted pyrazolo[1,5-a] pyrimidines as protein kinase inhibitors
|
|
ATE533770T1
(de)
|
2005-10-06 |
2011-12-15 |
Schering Corp |
Pyrazolopyrimidine als proteinkinaseinhibitoren
|
|
BRPI0616985B1
(pt)
|
2005-10-06 |
2021-10-26 |
Merck Sharp & Dohme Corp. |
Composto de pirazolo[1,5-a]pirimidina, e, uso de um composto
|
|
US8101625B2
(en)
|
2005-10-21 |
2012-01-24 |
Exelixis, Inc. |
Pyrimidinones as Casein Kinase II (CK2) modulators
|
|
KR101071438B1
(ko)
|
2005-10-21 |
2011-10-10 |
미쓰비시 타나베 파마 코퍼레이션 |
카나비노이드 수용체 길항제로서의피라졸로[1,5-a]피리미딘 화합물
|
|
US20100273776A1
(en)
|
2006-03-29 |
2010-10-28 |
FOLDRx PHARMACEUTICALS, INC |
Inhibition of alpha-synuclein toxicity
|
|
JP2009538304A
(ja)
|
2006-05-22 |
2009-11-05 |
シェーリング コーポレイション |
CDK阻害剤としてのピラゾロ[1,5−a]ピリミジン
|
|
AR061793A1
(es)
|
2006-07-05 |
2008-09-24 |
Mitsubishi Tanabe Pharma Corp |
Compuesto de pirazolo[1,5-a] pirimidina y composicion farmaceutica
|
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
PE20121506A1
(es)
|
2006-07-14 |
2012-11-26 |
Amgen Inc |
Compuestos triazolopiridinas como inhibidores de c-met
|
|
US8198448B2
(en)
|
2006-07-14 |
2012-06-12 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
WO2008063671A2
(en)
|
2006-11-20 |
2008-05-29 |
Alantos Pharmaceuticals Holding, Inc. |
Heterobicyclic metalloprotease inhibitors
|
|
EP2014661A1
(de)
|
2007-06-13 |
2009-01-14 |
Bayer CropScience AG |
Heterocyclisch substituierte Heterocyclyl-carbonsäurederivate
|
|
WO2009006580A1
(en)
|
2007-07-05 |
2009-01-08 |
Cv Therapeutics, Inc. |
Optionally condensed dihydropyridine, dihydropyrimidine and dihydropyrane derivatives acting as late sodium channel blockers
|
|
US20090012103A1
(en)
|
2007-07-05 |
2009-01-08 |
Matthew Abelman |
Substituted heterocyclic compounds
|
|
WO2009017954A1
(en)
|
2007-08-01 |
2009-02-05 |
Phenomix Corporation |
Inhibitors of jak2 kinase
|
|
CA2706946A1
(en)
|
2007-11-28 |
2009-06-04 |
Schering Corporation |
2-fluoropyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
|
|
WO2009075790A1
(en)
|
2007-12-07 |
2009-06-18 |
Alantos Pharmaceuticals Holding, Inc. |
Metalloprotease inhibitors for intra-articular application
|
|
SG187426A1
(en)
|
2008-01-04 |
2013-02-28 |
Intellikine Llc |
Certain chemical entities, compositions and methods
|
|
EP2085398A1
(en)
|
2008-02-01 |
2009-08-05 |
Merz Pharma GmbH & Co. KGaA |
Pyrazolopyrimidines, a process for their preparation and their use as medicine
|
|
WO2009117157A1
(en)
|
2008-03-20 |
2009-09-24 |
Amgen Inc. |
Aurora kinase modulators and method of use
|
|
CA2730106A1
(en)
|
2008-07-08 |
2010-01-14 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
|
AU2009279936A1
(en)
|
2008-08-05 |
2010-02-11 |
Banyu Pharmaceutical Co., Ltd. |
Therapeutic compounds
|
|
JP2012503623A
(ja)
|
2008-09-24 |
2012-02-09 |
ビーエーエスエフ ソシエタス・ヨーロピア |
無脊椎動物系害虫防除用ピラゾール化合物
|
|
CN102271515B
(zh)
|
2008-10-31 |
2014-07-02 |
健泰科生物技术公司 |
吡唑并嘧啶jak抑制剂化合物和方法
|
|
WO2010059836A1
(en)
|
2008-11-20 |
2010-05-27 |
Decode Genetics Ehf |
Substituted aza-bridged bicyclics for cardiovascular and cns disease
|
|
WO2010086040A1
(en)
|
2009-01-29 |
2010-08-05 |
Biomarin Iga, Ltd. |
Pyrazolo-pyrimidines for treatment of duchenne muscular dystrophy
|
|
US20100204265A1
(en)
|
2009-02-09 |
2010-08-12 |
Genelabs Technologies, Inc. |
Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections
|
|
CN101537007A
(zh)
|
2009-03-18 |
2009-09-23 |
中国医学科学院血液病医院(血液学研究所) |
N-(噻吩-2)吡唑并[1,5-a]嘧啶-3-甲酰胺类化合物在制备抗恶性肿瘤药物方面的应用
|
|
UA110324C2
(en)
*
|
2009-07-02 |
2015-12-25 |
Genentech Inc |
Jak inhibitory compounds based on pyrazolo pyrimidine
|
|
JP5819831B2
(ja)
|
2009-08-17 |
2015-11-24 |
インテリカイン, エルエルシー |
複素環式化合物およびそれらの使用
|
|
CN101671336B
(zh)
|
2009-09-23 |
2013-11-13 |
辽宁利锋科技开发有限公司 |
芳杂环并嘧啶衍生物和类似物及其制备方法和用途
|
|
CN102762208A
(zh)
|
2009-12-04 |
2012-10-31 |
赛林药物股份有限公司 |
作为ck2抑制剂的吡唑嘧啶和相关杂环
|
|
BR112012023576B1
(pt)
|
2010-03-18 |
2022-08-23 |
Institut Pasteur Korea |
Compostos anti-infecciosos e composições compreendendo os mesmos
|
|
WO2011121096A1
(en)
|
2010-03-31 |
2011-10-06 |
Dkfz Deutsches Krebsforschungszentrum |
PYRAZOL[1,5-a]PYRIMIDINE DERIVATIVES AS WNT PATHWAY ANTAGONISTS
|
|
NZ605627A
(en)
|
2010-06-23 |
2015-06-26 |
Vertex Pharma |
Pyrrolo-pyrazine derivatives useful as inhibitors of atr kinase
|
|
RS54761B1
(sr)
|
2010-06-24 |
2016-10-31 |
Gilead Sciences |
Pirazolo[1,5-a]pirimidini i-triazini kao antiviralni agensi
|
|
KR101995013B1
(ko)
*
|
2010-07-13 |
2019-07-02 |
에프. 호프만-라 로슈 아게 |
Irak4 조절제로서 피라졸로[1,5a]피리미딘 및 티에노[3,2b]피리미딘 유도체
|
|
WO2012022045A1
(en)
|
2010-08-20 |
2012-02-23 |
Hutchison Medipharma Limited |
Pyrrolopyrimidine compounds and uses thereof
|
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
|
US8609669B2
(en)
|
2010-11-16 |
2013-12-17 |
Abbvie Inc. |
Potassium channel modulators
|
|
HRP20220512T1
(hr)
|
2010-12-08 |
2022-05-27 |
The U.S.A. As Represented By The Secretary, Department Of Health And Human Services |
Supstituirani pirazolopirimidini kao aktivatori glukocerebrozidaze
|
|
ES2583086T3
(es)
|
2011-04-21 |
2016-09-19 |
Bayer Intellectual Property Gmbh |
Pirazolopiridinas sustituidas con fluoroalquilo y su uso
|
|
US9029389B2
(en)
|
2011-04-21 |
2015-05-12 |
Institut Pasteur Korea |
Anti-inflammation compounds
|
|
AU2012272815B2
(en)
|
2011-06-22 |
2017-09-07 |
The General Hospital Corporation |
Treatment of proteinopathies
|
|
JP2014522818A
(ja)
|
2011-06-22 |
2014-09-08 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Atrキナーゼ阻害剤として有用な化合物
|
|
EP2723746A1
(en)
|
2011-06-22 |
2014-04-30 |
Vertex Pharmaceuticals Inc. |
Compounds useful as inhibitors of atr kinase
|
|
WO2012178123A1
(en)
|
2011-06-22 |
2012-12-27 |
Vertex Pharmaceuticals Incorporated |
Compounds useful as inhibitors of atr kinase
|
|
JP2014520863A
(ja)
|
2011-07-13 |
2014-08-25 |
ファーマサイクリックス,インク. |
Bruton型チロシンキナーゼの阻害剤
|
|
WO2013052263A2
(en)
|
2011-09-16 |
2013-04-11 |
Microbiotix, Inc. |
Antifungal compounds
|
|
WO2013138436A1
(en)
|
2012-03-14 |
2013-09-19 |
Bristol-Myers Squibb Company |
Cyclolic hydrazine derivatives as hiv attachment inhibitors
|
|
EA031183B1
(ru)
|
2012-04-02 |
2018-11-30 |
Сайтокинетикс, Инк. |
Способы улучшения функции диафрагмы
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
CN103373996A
(zh)
|
2012-04-20 |
2013-10-30 |
山东亨利医药科技有限责任公司 |
作为crth2受体拮抗剂的二并环衍生物
|
|
RU2014146778A
(ru)
|
2012-05-23 |
2016-07-10 |
Савира Фармасьютикалз Гмбх |
Производные 7-оксо-4,7-дигидропиразоло[1,5-а]пиримидина, которые пригодны для лечения, уменьшения интенсивности или предупреждения вирусного заболевания
|
|
JP2015517555A
(ja)
|
2012-05-23 |
2015-06-22 |
ザヴィラ ファーマシューティカルズ ゲーエムベーハー |
7−オキソ−チアゾロピリジン炭酸誘導体及びウイルス性疾患の治療、改善又は予防におけるその使用
|
|
US20140018361A1
(en)
|
2012-07-11 |
2014-01-16 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
WO2014015523A1
(en)
|
2012-07-27 |
2014-01-30 |
Hutchison Medipharma Limited |
Novel heteroaryl and heterocycle compounds, compositions and methods
|
|
HK1210177A1
(en)
|
2012-08-06 |
2016-04-15 |
Savira Pharmaceuticals Gmbh |
Dihydroxypyrimidine carbonic acid derivatives and their use in treatment, amelioration or prevention of a viral disease
|
|
EP2895475B1
(en)
|
2012-08-09 |
2016-11-09 |
VIIV Healthcare UK (No.5) Limited |
Tricyclic amidine derivatives as hiv attachment inhibitors
|
|
EP2895472B1
(en)
|
2012-08-09 |
2016-11-23 |
VIIV Healthcare UK (No.5) Limited |
Tricyclic alkene derivatives as HIV attachment inhibitors
|
|
US9505752B2
(en)
|
2012-08-09 |
2016-11-29 |
Viiv Healthcare Uk (No. 5) Limited |
Piperidine amide derivatives as HIV attachment inhibitors
|
|
AU2013304133B2
(en)
|
2012-08-17 |
2017-02-23 |
Bayer Cropscience Ag |
Azaindole carboxylic acid amides and azaindole thiocarboxylic acid amides for use as insecticides and acaricides
|
|
JP6258937B2
(ja)
|
2012-08-24 |
2018-01-10 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
新規二環式ピリジン誘導体
|
|
WO2014035140A2
(en)
|
2012-08-30 |
2014-03-06 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating histone methyltransferase activity
|
|
EP2909212B1
(en)
|
2012-09-07 |
2017-02-22 |
Takeda Pharmaceutical Company Limited |
Substituted 1,4-dihydropyrazolo[4,3-b]indoles
|
|
WO2014042433A2
(en)
|
2012-09-14 |
2014-03-20 |
Kainos Medicine, Inc. |
Compounds and compositions for modulating adenosine a3 receptor activity
|
|
TW201412740A
(zh)
|
2012-09-20 |
2014-04-01 |
Bayer Pharma AG |
經取代之吡咯并嘧啶胺基苯并噻唑酮
|
|
CN104812389B
(zh)
|
2012-09-24 |
2020-07-17 |
润新生物公司 |
某些化学实体、组合物及方法
|
|
EP2909214B1
(en)
|
2012-10-22 |
2020-07-22 |
City of Hope |
Etp derivatives
|
|
BR112015003160A2
(pt)
|
2012-10-24 |
2017-07-04 |
Becton Dickinson Co |
corantes de azaindolina - cianina substituídos por hidroxamato e bioconjugados dos mesmos
|
|
HK1209746A1
(en)
|
2012-12-07 |
2016-04-08 |
沃泰克斯药物股份有限公司 |
Compounds useful as inhibitors of atr kinase
|