JP2016512232A5 - - Google Patents
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- JP2016512232A5 JP2016512232A5 JP2015562913A JP2015562913A JP2016512232A5 JP 2016512232 A5 JP2016512232 A5 JP 2016512232A5 JP 2015562913 A JP2015562913 A JP 2015562913A JP 2015562913 A JP2015562913 A JP 2015562913A JP 2016512232 A5 JP2016512232 A5 JP 2016512232A5
- Authority
- JP
- Japan
- Prior art keywords
- hydroxypropyl
- carbamate
- chlorophenyl
- group
- dichlorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361776926P | 2013-03-12 | 2013-03-12 | |
| US61/776,926 | 2013-03-12 | ||
| PCT/KR2014/002005 WO2014142518A1 (en) | 2013-03-12 | 2014-03-11 | Phenyl carbamate compounds for use in preventing or treating a movement disorder |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512232A JP2016512232A (ja) | 2016-04-25 |
| JP2016512232A5 true JP2016512232A5 (enExample) | 2017-08-31 |
| JP6200526B2 JP6200526B2 (ja) | 2017-09-20 |
Family
ID=51530016
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562906A Active JP6062077B2 (ja) | 2013-03-12 | 2014-03-07 | 小児てんかん及びてんかん関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| JP2015562915A Active JP6062078B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん及びてんかん−関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| JP2015562914A Active JP6215971B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌａｌｋｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｅｐｉｌｅｐｓｙｏｒｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅ｝ |
| JP2015562913A Active JP6200526B2 (ja) | 2013-03-12 | 2014-03-11 | 運動障害の予防又は治療用フェニルカルバメート化合物 |
| JP2017133937A Pending JP2017206546A (ja) | 2013-03-12 | 2017-07-07 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌ ａｌｋｙｌ ｃａｒｂａｍａｔｅ ｃｏｍｐｏｕｎｄｓｆｏｒ ｕｓｅ ｉｎ ｐｒｅｖｅｎｔｉｎｇ ｏｒ ｔｒｅａｔｉｎｇ ｅｐｉｌｅｐｓｙ ｏｒ ｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄ ｓｙｎｄｒｏｍｅ｝ |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562906A Active JP6062077B2 (ja) | 2013-03-12 | 2014-03-07 | 小児てんかん及びてんかん関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| JP2015562915A Active JP6062078B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん及びてんかん−関連症侯群の予防又は治療用フェニルカルバメート化合物｛ｐｈｅｎｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｐｅｄｉａｔｒｉｃｅｐｉｌｅｓｙａｎｄｅｐｉｌｅｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅｓ｝ |
| JP2015562914A Active JP6215971B2 (ja) | 2013-03-12 | 2014-03-11 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌａｌｋｙｌｃａｒｂａｍａｔｅｃｏｍｐｏｕｎｄｓｆｏｒｕｓｅｉｎｐｒｅｖｅｎｔｉｎｇｏｒｔｒｅａｔｉｎｇｅｐｉｌｅｐｓｙｏｒｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄｓｙｎｄｒｏｍｅ｝ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017133937A Pending JP2017206546A (ja) | 2013-03-12 | 2017-07-07 | てんかん又はてんかん−関連症侯群の予防又は治療用フェニルアルキルカルバメート化合物｛ｐｈｅｎｙｌ ａｌｋｙｌ ｃａｒｂａｍａｔｅ ｃｏｍｐｏｕｎｄｓｆｏｒ ｕｓｅ ｉｎ ｐｒｅｖｅｎｔｉｎｇ ｏｒ ｔｒｅａｔｉｎｇ ｅｐｉｌｅｐｓｙ ｏｒ ｅｐｉｌｅｐｓｙ−ｒｅｌａｔｅｄ ｓｙｎｄｒｏｍｅ｝ |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US9872847B2 (enExample) |
| EP (4) | EP2968210B1 (enExample) |
| JP (5) | JP6062077B2 (enExample) |
| KR (5) | KR101717872B1 (enExample) |
| CN (6) | CN105228604A (enExample) |
| ES (3) | ES2998534T3 (enExample) |
| WO (4) | WO2014142477A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2998534T3 (en) * | 2013-03-12 | 2025-02-20 | Bio Pharm Solutions Co Ltd | Phenyl carbamate compounds for use in preventing or treating pediatric epilesy |
| CN105189450B (zh) | 2013-03-12 | 2019-09-13 | 比皮艾思药物研发有限公司 | 氨基甲酸苯酯化合物及包含该化合物的用于预防或治疗精神障碍的组合物 |
| WO2017150903A1 (en) | 2016-02-29 | 2017-09-08 | Bio-Pharm Solutions Co., Ltd. | Sulfamate derivative compounds, processes for preparing them and their uses |
| KR102635941B1 (ko) * | 2016-12-14 | 2024-02-13 | 에스케이바이오팜 주식회사 | 진전 또는 진전 증후군의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도 |
| CN109920550A (zh) * | 2018-12-25 | 2019-06-21 | 天津大学 | 一种基于dMRI研究青少年肌阵挛性癫痫的方法 |
| EP4204395A4 (en) * | 2020-08-31 | 2024-08-07 | Bio-Pharm Solutions Co., Ltd. | Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease |
| EP4211125A4 (en) | 2020-09-10 | 2024-10-02 | Bio-Pharm Solutions Co., Ltd. | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING A PSYCHIATRIC DISORDER |
| US12054449B2 (en) | 2021-08-05 | 2024-08-06 | Bio-Pharm Solutions Co., Ltd. | Phenylcarbamate crystalline form and method for manufacturing the same |
| CN119552104B (zh) * | 2024-12-03 | 2025-07-15 | 西安瑞谱源生物技术有限公司 | 一种氘代维生素a的制备方法 |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3313697A (en) | 1962-06-26 | 1967-04-11 | Armour Pharma | Carbamate compositions for and methods of treating the central nervous system |
| US3313696A (en) | 1962-06-26 | 1967-04-11 | Armour Pharmacentical Company | Carbamate sedative compositions and method of use |
| US3313699A (en) | 1962-06-26 | 1967-04-11 | Armour Pharma | Compositions for and method of treating the central nervous system |
| US3265728A (en) * | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US3313700A (en) * | 1962-07-18 | 1967-04-11 | Armour Pharmacentical Company | Method of treating the central nervous system with substituted phenethyl carbamates and compositions therefor |
| FR5671M (enExample) * | 1965-04-23 | 1968-01-02 | ||
| JPS61271992A (ja) | 1985-05-28 | 1986-12-02 | Central Glass Co Ltd | 光学活性ジオ−ルの製造方法 |
| US5258397A (en) | 1988-11-30 | 1993-11-02 | Novapharme | 3-Isoxazoyl derivatives endowed with anticonvulsant activity, procedure for their preparation and their pharmaceutical compositions |
| FR2686084B1 (fr) * | 1992-01-10 | 1995-12-22 | Bioprojet Soc Civ | Nouveaux derives de l'imidazole, leur preparation et leurs applications therapeutiques. |
| KR100197901B1 (ko) * | 1994-02-21 | 1999-06-15 | 남창우 | 페닐-1,2-에탄디올 광학이성체의 단일 카바메이트 |
| US20100210590A1 (en) * | 1995-09-27 | 2010-08-19 | Northwestern University | Compositions and treatments for seizure-related disorders |
| US5698588A (en) | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| US20010034365A1 (en) * | 1996-01-16 | 2001-10-25 | Choi Yong Moon | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| UA65607C2 (uk) * | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
| WO2002051395A1 (en) | 1998-05-28 | 2002-07-04 | Codon Pharmaceuticals, Inc. | Treatment of neurodegenerative diseases |
| AR020115A1 (es) * | 1998-08-06 | 2002-04-10 | Daiichi Seiyaku Co | Agente terapeutico o preventivo para epilepsias rebeldes y uso del compuesto para la produccion de los mismos |
| CN1503665A (zh) | 2001-02-27 | 2004-06-09 | ����-������ҩƷ��˾ | 用于预防或治疗焦虑症的氨基甲酸酯化合物 |
| JP2004527492A (ja) * | 2001-02-27 | 2004-09-09 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 運動障害の予防もしくは治療における使用のためのカルバメート化合物 |
| RU2283106C2 (ru) | 2001-02-27 | 2006-09-10 | Орто-Макнейл Фармасьютикал, Инк. | Производные карбаматов для использования для лечения боли |
| PT1383489E (pt) | 2001-02-27 | 2007-06-21 | Ortho Mcneil Pharm Inc | Compostos carbamato para utilização na prevenção ou tratamento de distúrbios neurodegenerativos |
| PT1401424E (pt) | 2001-02-27 | 2007-02-28 | Ortho Mcneil Pharm Inc | Compostos carbamato para utilização na prevenção ou tratamento de distúrbios psicóticos |
| US7199135B2 (en) * | 2001-07-05 | 2007-04-03 | H. Lundbeck A/S | Substituted alkyl amido piperidines |
| JP4635130B2 (ja) * | 2002-06-11 | 2011-02-16 | 株式会社医薬分子設計研究所 | 神経変性疾患治療剤 |
| DK1809273T3 (da) | 2004-09-16 | 2010-08-02 | Janssen Pharmaceutica Nv | Anvendelse af 2-phenyl-1,2-ethandiol-(di)carbamater til behandling af epileptogenese |
| EP1717235A3 (en) * | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
| US20070021501A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods of treating epileptogenesis |
| US7737141B2 (en) | 2006-07-28 | 2010-06-15 | Eisai R&D Management Co., Ltd. | Prodrug of cinnamide compound |
| AU2007313017A1 (en) | 2006-10-13 | 2008-04-24 | Janssen Pharmaceutica, N.V. | Phenylalkylamino carbamate compositions |
| MX2009003929A (es) * | 2006-10-13 | 2009-06-26 | Janssen Pharmaceutica Nv | Composiciones de fenilalquil carbamato. |
| EP2079465A2 (en) | 2006-10-27 | 2009-07-22 | Janssen Pharmaceutica N.V. | Methods for treatment of cochlear and vestibular disorders |
| JP2010508355A (ja) | 2006-10-30 | 2010-03-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 鬱病を処置する方法 |
| US7863499B2 (en) | 2007-02-08 | 2011-01-04 | Albert Einstein College Of Medicine Of Yeshiva University | Model of infantile spasm syndrome |
| JP2010524858A (ja) | 2007-04-10 | 2010-07-22 | エスジーエックス ファーマシューティカルズ、インコーポレイテッド | 縮合環複素環キナーゼ調節因子 |
| CN102159077A (zh) | 2008-08-21 | 2011-08-17 | 吉瑞工厂 | 用于治疗神经性疼痛的方法 |
| AU2009300607C1 (en) | 2008-10-02 | 2014-08-07 | Taisho Pharmaceutical Co., Ltd. | 7-piperidinoalkyl-3,4-dihydroquinolone derivative |
| CN102448937A (zh) | 2009-05-29 | 2012-05-09 | 拉夸里亚创药株式会社 | 作为钙或钠通道阻滞剂的芳基取代羧酰胺衍生物 |
| JP2013501026A (ja) * | 2009-08-05 | 2013-01-10 | クオンベルゲンセ プハルマセウトイカルス リミテッド | てんかん及び関連疾患の治療のための共治療法 |
| KR101532823B1 (ko) * | 2010-07-02 | 2015-07-03 | (주)바이오팜솔루션즈 | 페닐 카바메이트 화합물 및 이를 포함하는 근육 이완제 |
| US9018253B2 (en) | 2010-07-02 | 2015-04-28 | Bio-Pharm Solutions Co., Ltd. | Phenylcarbamate compound and muscle relaxant containing the same |
| CA2815460C (en) * | 2011-01-13 | 2017-04-18 | Bio-Pharm Solutions Co., Ltd. | Process for preparation of phenyl carbamate derivatives |
| EP2797878B1 (en) | 2011-12-27 | 2017-08-16 | Bio-Pharm Solutions Co., Ltd. | Phenyl carbamate compounds for use in preventing or treating stroke |
| CN105189450B (zh) | 2013-03-12 | 2019-09-13 | 比皮艾思药物研发有限公司 | 氨基甲酸苯酯化合物及包含该化合物的用于预防或治疗精神障碍的组合物 |
| ES2998534T3 (en) * | 2013-03-12 | 2025-02-20 | Bio Pharm Solutions Co Ltd | Phenyl carbamate compounds for use in preventing or treating pediatric epilesy |
-
2014
- 2014-03-07 ES ES14762362T patent/ES2998534T3/es active Active
- 2014-03-07 CN CN201480015460.XA patent/CN105228604A/zh active Pending
- 2014-03-07 WO PCT/KR2014/001903 patent/WO2014142477A1/en not_active Ceased
- 2014-03-07 CN CN201910335069.2A patent/CN109939092B/zh active Active
- 2014-03-07 EP EP14762362.3A patent/EP2968210B1/en active Active
- 2014-03-07 KR KR1020157026389A patent/KR101717872B1/ko active Active
- 2014-03-07 JP JP2015562906A patent/JP6062077B2/ja active Active
- 2014-03-11 US US14/775,092 patent/US9872847B2/en active Active
- 2014-03-11 WO PCT/KR2014/002006 patent/WO2014142519A1/en not_active Ceased
- 2014-03-11 CN CN201480015472.2A patent/CN105188689B/zh active Active
- 2014-03-11 WO PCT/KR2014/002005 patent/WO2014142518A1/en not_active Ceased
- 2014-03-11 KR KR1020157026390A patent/KR101717873B1/ko active Active
- 2014-03-11 JP JP2015562915A patent/JP6062078B2/ja active Active
- 2014-03-11 US US14/775,189 patent/US9682059B2/en active Active
- 2014-03-11 JP JP2015562914A patent/JP6215971B2/ja active Active
- 2014-03-11 ES ES14764907T patent/ES3046835T3/es active Active
- 2014-03-11 CN CN201480015516.1A patent/CN105188690B/zh active Active
- 2014-03-11 CN CN202010408166.2A patent/CN111419830B/zh active Active
- 2014-03-11 KR KR1020157026378A patent/KR20150120518A/ko not_active Ceased
- 2014-03-11 US US14/774,287 patent/US9504668B2/en active Active
- 2014-03-11 CN CN201480015456.3A patent/CN105209027A/zh active Pending
- 2014-03-11 EP EP14764907.3A patent/EP2968212B1/en active Active
- 2014-03-11 JP JP2015562913A patent/JP6200526B2/ja active Active
- 2014-03-11 EP EP14765077.4A patent/EP2968213A4/en not_active Withdrawn
- 2014-03-11 KR KR1020177013680A patent/KR101992035B1/ko active Active
- 2014-03-11 EP EP14764227.6A patent/EP2968211B1/en active Active
- 2014-03-11 WO PCT/KR2014/002007 patent/WO2014142520A1/en not_active Ceased
- 2014-03-11 KR KR1020157026369A patent/KR101739676B1/ko active Active
- 2014-03-11 ES ES14764227T patent/ES2881850T3/es active Active
- 2014-03-11 US US14/204,298 patent/US20140275243A1/en not_active Abandoned
-
2016
- 2016-06-22 US US15/190,123 patent/US9956197B2/en active Active
-
2017
- 2017-07-07 JP JP2017133937A patent/JP2017206546A/ja active Pending
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