MX2009004553A - Metodos para el tratamiento de trastornos cocleares y vestibulares. - Google Patents

Metodos para el tratamiento de trastornos cocleares y vestibulares.

Info

Publication number
MX2009004553A
MX2009004553A MX2009004553A MX2009004553A MX2009004553A MX 2009004553 A MX2009004553 A MX 2009004553A MX 2009004553 A MX2009004553 A MX 2009004553A MX 2009004553 A MX2009004553 A MX 2009004553A MX 2009004553 A MX2009004553 A MX 2009004553A
Authority
MX
Mexico
Prior art keywords
formula
group
methods
phenyl
alkyl
Prior art date
Application number
MX2009004553A
Other languages
English (en)
Inventor
Magali Haas
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of MX2009004553A publication Critical patent/MX2009004553A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención está dirigida a métodos para proveer otoprotección, que comprenden administrar a un sujeto que necesita la misma una cantidad terapéuticamente efectiva de un compuesto seleccionado del grupo que consiste de la fórmula (I) y la fórmula (II) (ver fórmulas) o una sal o éster farmacéuticamente aceptable del mismo, en donde fenilo es sustituido en X con uno a cinco átomos de halógeno seleccionandos del grupo que consiste de flúor, cloro, bromo y yodo; y, R1, R2, R3, R4, R5 Y R6 se seleccionan independientemente del grupo que consiste de hidrógeno y alquilo de C1-C4; en donde alquilo de C1-C4 es opcionalmente sustituido con fenilo (en donde fenilo es opcionalmente sustituido con sustituyentes independientemente seleccionados del grupo que consiste de halógeno, alquilo de C1-C4, alcoxi de C1-C4, amino, nitro y ciano).
MX2009004553A 2006-10-27 2007-10-11 Metodos para el tratamiento de trastornos cocleares y vestibulares. MX2009004553A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86314406P 2006-10-27 2006-10-27
PCT/US2007/081031 WO2008060787A2 (en) 2006-10-27 2007-10-11 Methods for treatment of cochlear and vestibular disorders

Publications (1)

Publication Number Publication Date
MX2009004553A true MX2009004553A (es) 2009-11-10

Family

ID=39402353

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009004553A MX2009004553A (es) 2006-10-27 2007-10-11 Metodos para el tratamiento de trastornos cocleares y vestibulares.

Country Status (16)

Country Link
US (1) US20080103198A1 (es)
EP (1) EP2079465A2 (es)
JP (1) JP2010523468A (es)
KR (1) KR20090085071A (es)
CN (1) CN101568335A (es)
AU (1) AU2007319578A1 (es)
BR (1) BRPI0718316A2 (es)
CA (1) CA2667587A1 (es)
CO (1) CO6180505A2 (es)
CR (1) CR10830A (es)
EA (1) EA200970424A1 (es)
IL (1) IL198395A0 (es)
MX (1) MX2009004553A (es)
NO (1) NO20091658L (es)
WO (1) WO2008060787A2 (es)
ZA (1) ZA200903653B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9018253B2 (en) 2010-07-02 2015-04-28 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
CA2815460C (en) 2011-01-13 2017-04-18 Bio-Pharm Solutions Co., Ltd. Process for preparation of phenyl carbamate derivatives
RU2475223C1 (ru) * 2011-07-06 2013-02-20 Государственное образовательное учреждение высшего профессионального образования "Самарский государственный медицинский университет" Министерства здравоохранения и социального развития Российской Федерации Способ лечения кохлео-вестибулярных расстройств у пациентов с остеохондрозом шейного отдела позвоночника
EP2797881B1 (en) 2011-12-27 2018-11-14 Bio-Pharm Solutions Co., Ltd. Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same
KR101717872B1 (ko) 2013-03-12 2017-03-17 (주)바이오팜솔루션즈 소아 간질 및 간질-관련 증후군의 예방 또는 치료용 페닐카바메이트 화합물

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
GB0024517D0 (en) * 2000-10-06 2000-11-22 Glaxo Group Ltd Use of medicaments
SE0100344D0 (sv) * 2001-02-05 2001-02-05 Jan Nordmark New Use

Also Published As

Publication number Publication date
CN101568335A (zh) 2009-10-28
EP2079465A2 (en) 2009-07-22
BRPI0718316A2 (pt) 2014-07-01
AU2007319578A1 (en) 2008-05-22
KR20090085071A (ko) 2009-08-06
CR10830A (es) 2009-09-29
NO20091658L (no) 2009-05-25
US20080103198A1 (en) 2008-05-01
ZA200903653B (en) 2010-08-25
CA2667587A1 (en) 2008-05-22
EA200970424A1 (ru) 2010-04-30
CO6180505A2 (es) 2010-07-19
WO2008060787A2 (en) 2008-05-22
JP2010523468A (ja) 2010-07-15
IL198395A0 (en) 2010-02-17
WO2008060787A3 (en) 2008-08-28

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