JP2016512047A5 - - Google Patents
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- JP2016512047A5 JP2016512047A5 JP2016502782A JP2016502782A JP2016512047A5 JP 2016512047 A5 JP2016512047 A5 JP 2016512047A5 JP 2016502782 A JP2016502782 A JP 2016502782A JP 2016502782 A JP2016502782 A JP 2016502782A JP 2016512047 A5 JP2016512047 A5 JP 2016512047A5
- Authority
- JP
- Japan
- Prior art keywords
- host cell
- synthase
- genetically modified
- modified host
- enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361800356P | 2013-03-15 | 2013-03-15 | |
| US61/800,356 | 2013-03-15 | ||
| PCT/US2014/028421 WO2014144135A2 (en) | 2013-03-15 | 2014-03-14 | Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019175333A Division JP2019213558A (ja) | 2013-03-15 | 2019-09-26 | アセチル補酵素ａ由来化合物を生産するためのホスホケトラーゼおよびホスホトランスアセチラーゼの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512047A JP2016512047A (ja) | 2016-04-25 |
| JP2016512047A5 true JP2016512047A5 (https=) | 2017-04-20 |
| JP6595449B2 JP6595449B2 (ja) | 2019-10-23 |
Family
ID=50391556
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502782A Active JP6595449B2 (ja) | 2013-03-15 | 2014-03-14 | アセチル補酵素ａ由来化合物を生産するためのホスホケトラーゼおよびホスホトランスアセチラーゼの使用 |
| JP2019175333A Pending JP2019213558A (ja) | 2013-03-15 | 2019-09-26 | アセチル補酵素ａ由来化合物を生産するためのホスホケトラーゼおよびホスホトランスアセチラーゼの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019175333A Pending JP2019213558A (ja) | 2013-03-15 | 2019-09-26 | アセチル補酵素ａ由来化合物を生産するためのホスホケトラーゼおよびホスホトランスアセチラーゼの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9410214B2 (https=) |
| EP (1) | EP2971027B1 (https=) |
| JP (2) | JP6595449B2 (https=) |
| KR (1) | KR102159691B1 (https=) |
| CN (1) | CN105189772B (https=) |
| AU (1) | AU2014227811C1 (https=) |
| BR (1) | BR112015023089A2 (https=) |
| CA (1) | CA2903053C (https=) |
| ES (1) | ES2721920T3 (https=) |
| MX (1) | MX364748B (https=) |
| MY (1) | MY171958A (https=) |
| WO (1) | WO2014144135A2 (https=) |
| ZA (1) | ZA201506406B (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013066568A1 (en) * | 2011-10-07 | 2013-05-10 | Danisco Us Inc. | Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene |
| WO2014081803A1 (en) | 2012-11-20 | 2014-05-30 | Mascoma Corporation | An electron consuming ethanol production pathway to displace glycerol formation in s. cerevisiae |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| US20160376600A1 (en) | 2013-11-25 | 2016-12-29 | Genomatica, Inc. | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol |
| WO2015084633A1 (en) | 2013-12-03 | 2015-06-11 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis |
| WO2016044713A1 (en) * | 2014-09-18 | 2016-03-24 | Genomatica, Inc. | Non-natural microbial organisms with improved energetic efficiency |
| CN104372017B (zh) * | 2014-11-05 | 2017-06-30 | 中国科学院青岛生物能源与过程研究所 | 一种提高基因工程菌异戊二烯及其衍生物产量的方法及应用 |
| WO2017051930A1 (en) * | 2015-09-25 | 2017-03-30 | Ajinomoto Co., Inc. | Method of producing isoprenoid compound |
| CN108235682A (zh) | 2015-09-29 | 2018-06-29 | 金伯利-克拉克环球有限公司 | 用于维护微生物群落的健康平衡的协同组合物 |
| GB201519088D0 (en) * | 2015-10-28 | 2015-12-09 | Metabogen Ab | The use of bacteria formulations |
| CN108473528B (zh) | 2015-10-29 | 2026-01-16 | 弗门尼舍公司 | 高强度甜味剂 |
| US10612032B2 (en) | 2016-03-24 | 2020-04-07 | The Board Of Trustees Of The Leland Stanford Junior University | Inducible production-phase promoters for coordinated heterologous expression in yeast |
| US20190309328A1 (en) * | 2016-10-28 | 2019-10-10 | Sekisui Chemical Co., Ltd. | Recombinant cells and method for producing isoprene or terpene |
| CN110268057B (zh) * | 2016-11-16 | 2024-03-29 | 斯坦福大学托管董事会 | 用于鉴定和表达基因簇的系统和方法 |
| CN110366594B (zh) * | 2016-12-16 | 2023-12-15 | 丹尼斯科美国公司 | 双功能磷酸转酮酶-磷酸转乙酰酶融合多肽 |
| CA3049126A1 (en) | 2017-01-25 | 2018-08-02 | Amyris Bio Products Portugal, Unipessoal, Lda | Co-production of isoprenoids |
| KR102769558B1 (ko) | 2017-02-28 | 2025-02-19 | 킴벌리-클라크 월드와이드, 인크. | 미생물총의 건강한 균형을 유지하기 위한 상승적 조성물 |
| US20200063166A1 (en) * | 2017-03-13 | 2020-02-27 | Dsm Ip Assets B.V. | Zinc binuclear cluster transcriptional regulator-deficient strain |
| SG11201910136RA (en) | 2017-05-03 | 2019-11-28 | Firmenich Incorporated | Methods for making high intensity sweeteners |
| US20200095621A1 (en) * | 2017-05-16 | 2020-03-26 | The Regents Of The University Of California | Methods and compositions for 3-hydroxypropionate production |
| US11103808B2 (en) | 2017-08-07 | 2021-08-31 | Amyris, Inc. | Process for recovering isoprenoids produced by microorganisms |
| WO2019030007A1 (en) | 2017-08-07 | 2019-02-14 | Total Raffinage Chimie | PROCESS FOR RECOVERING FERMENTATION PRODUCTS |
| JP2019041712A (ja) * | 2017-09-05 | 2019-03-22 | 株式会社デンソー | 組み換え体及びスクアレンの製造方法 |
| CN111655855B (zh) | 2017-09-14 | 2025-09-09 | 生命明疗法股份有限公司 | 人治疗靶标及其调节剂 |
| CA3084263A1 (en) | 2017-12-07 | 2019-06-13 | Zymergen Inc. | Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation |
| BR112020012704A8 (pt) | 2017-12-21 | 2022-03-03 | Zymergen Inc | Nepetalactol oxidorredutases, nepetalactol sintases, e micróbios capazes de produzir nepetalactona |
| CN112041449B (zh) | 2018-03-06 | 2024-07-05 | 丹尼斯科美国公司 | 通过过表达pab1的酵母来降低乙酸生产 |
| US20210047660A1 (en) * | 2018-03-06 | 2021-02-18 | Danisco Us Inc. | Compositions and methods for increasing ethanol production by yeast using gcy1 and dak1 |
| EP3821022A1 (en) | 2018-07-12 | 2021-05-19 | Amyris, Inc. | Methods for controlling fermentation feed rates |
| MX2021005219A (es) | 2018-11-07 | 2021-06-18 | Firmenich Incorporated | Metodos para hacer edulcorantes de alta intensidad. |
| EP3860363A1 (en) | 2018-11-07 | 2021-08-11 | Firmenich Incorporated | Methods for making high intensity sweeteners |
| CN111378588A (zh) * | 2018-12-29 | 2020-07-07 | 中国科学院青岛生物能源与过程研究所 | 一种转化纤维素水解液合成法尼烯的基因工程菌及其应用 |
| JP2022532535A (ja) * | 2019-05-08 | 2022-07-15 | オークソリティック リミテッド | 栄養要求性選択方法 |
| WO2021022097A1 (en) * | 2019-08-01 | 2021-02-04 | Danisco Us Inc | Over-expression of adh5p for increased ethanol production by yeast |
| CN110628806B (zh) * | 2019-09-23 | 2021-09-21 | 华南理工大学 | 一种高产β-紫罗兰酮基因工程菌及其构建方法和应用 |
| CN111763662B (zh) * | 2019-11-29 | 2023-12-19 | 上海京新生物医药有限公司 | 酮还原酶及其在替格瑞洛中间体合成中的应用 |
| CN112342163A (zh) * | 2020-11-13 | 2021-02-09 | 华中农业大学 | 一种伯克霍尔德菌及其应用 |
| US11905544B2 (en) | 2020-12-17 | 2024-02-20 | Debut Biotechnology, Inc. | Dehydratase variants with improved specific activity for the production of pyruvate from glycerate |
| WO2022133213A1 (en) * | 2020-12-18 | 2022-06-23 | Debut Biotechnology, Inc. | Cell-free production of geranyl pyrophosphate from glycerol in a cell-free manufacturing system |
| US20220333118A1 (en) | 2021-04-13 | 2022-10-20 | Debut Biotechnology, Inc. | Flavonoid and anthocyanin bioproduction using microorganism hosts |
| CN113430215B (zh) * | 2021-06-03 | 2023-04-18 | 昆明理工大学 | 乙酰CoA合成酶基因RKACS1及其应用 |
| CN114480158B (zh) * | 2021-09-15 | 2023-02-03 | 安徽农业大学 | 一种戊糖片球菌及其在棉酚降解中的应用 |
| WO2023244843A1 (en) | 2022-06-16 | 2023-12-21 | Amyris, Inc. | HIGH pH METHODS AND COMPOSITIONS FOR CULTURING GENETICALLY MODIFIED HOST CELLS |
| NL2032683B1 (en) * | 2022-07-18 | 2024-01-26 | Sestina Bio Llc | Bioproduction of isoprenoids |
| CN115305226B (zh) * | 2022-09-22 | 2023-06-16 | 郑州轻工业大学 | 一株降解烟碱并产氢的抗辐射不动杆菌zj-22及其应用 |
| CN116926092B (zh) * | 2022-10-28 | 2024-04-26 | 昆明理工大学 | 一种泛酸激酶基因RkPank及其应用 |
| CN116064266B (zh) * | 2022-11-01 | 2024-06-14 | 四川大学 | 盐胁迫抗性增强的重组酿酒酵母菌及其构建方法与应用 |
| WO2024151689A1 (en) | 2023-01-10 | 2024-07-18 | Amyris, Inc. | Production of canthaxanthin |
| WO2024235968A1 (en) | 2023-05-15 | 2024-11-21 | Dsm Ip Assets B.V. | Method of reducing emulsion formationduring fermentation process |
| AR133254A1 (es) * | 2023-07-14 | 2025-09-10 | Danstar Ferment Ag | Aumento de la producción de acetil-coenzima a y productos derivados en levaduras |
| WO2025133860A1 (en) * | 2023-12-21 | 2025-06-26 | Danstar Ferment Ag | Increased production of acetyl-phosphate and products derived therefrom in yeasts |
| CN119639631B (zh) * | 2025-02-12 | 2025-05-23 | 云南省农业科学院农业环境资源研究所 | 一株草根围副伯克霍尔德氏菌及其菌剂与应用 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0118367B1 (en) | 1983-03-08 | 1989-04-26 | Merck & Co. Inc. | Recombinant dna cloning vector pve1, deletion and hybrid mutants, and recombinant derivatives thereof, products and processes |
| US4703009A (en) | 1983-03-08 | 1987-10-27 | Merck & Co., Inc. | RDNA cloning vector pVE1, deletion and hybrid mutants and recombinant derivatives thereof products and processes |
| US5272065A (en) | 1983-10-20 | 1993-12-21 | Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
| US5672497A (en) | 1986-03-21 | 1997-09-30 | Eli Lilly And Company | Method for increasing the antibiotic-producing ability of antibiotic-producing microorganisms |
| CA1340599C (en) | 1986-03-21 | 1999-06-22 | Karen Leigh Cox | Antibiotic-producing microorganisms |
| US5098837A (en) | 1988-06-07 | 1992-03-24 | Eli Lilly And Company | Macrolide biosynthetic genes for use in streptomyces and other organisms |
| US5149638A (en) | 1988-09-29 | 1992-09-22 | Eli Lilly And Company | Tylosin biosynthetic genes tylA, tylB and tylI |
| US5252474A (en) | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
| US6060234A (en) | 1991-01-17 | 2000-05-09 | Abbott Laboratories | Polyketide derivatives and recombinant methods for making same |
| US5824513A (en) | 1991-01-17 | 1998-10-20 | Abbott Laboratories | Recombinant DNA method for producing erythromycin analogs |
| WO1993013663A1 (en) | 1992-01-17 | 1993-07-22 | Abbott Laboratories | Method of directing biosynthesis of specific polyketides |
| US5849541A (en) | 1993-11-02 | 1998-12-15 | Merck & Co., Inc. | DNA encoding triol polyketide synthase |
| US5716849A (en) | 1994-06-08 | 1998-02-10 | Novartis Finance Corporation | Genes for the biosynthesis of soraphen |
| CA2197524A1 (en) | 1996-02-22 | 1997-08-22 | Bradley Stuart Dehoff | Polyketide synthase genes |
| CA2197160C (en) | 1996-02-22 | 2007-05-01 | Stanley Gene Burgett | Platenolide synthase gene |
| DE69736673T2 (de) | 1996-08-20 | 2007-09-13 | Novartis Ag | Rifamycin biosynthese genkluster |
| ID21555A (id) * | 1996-11-13 | 1999-06-24 | Du Pont | Metoda untuk produksi gliserol oleh organisme-organisme yang direkombinasi |
| JP2001511349A (ja) | 1997-07-25 | 2001-08-14 | ヘキスト・マリオン・ルセル | Ｓａｃｃｈａｒｏｐｏｌｙｓｐｏｒａｅｒｙｔｈｒａｅａ及びＳｔｒｅｐｔｏｍｙｃｅｓａｎｔｉｂｉｏｔｉｃｕｓにおける６−デオキシヘキソースの生合成及び移送のための遺伝子 |
| US6090601A (en) | 1998-01-23 | 2000-07-18 | Kosan Bioscience | Sorangium polyketide synthase |
| US6143526A (en) | 1998-03-09 | 2000-11-07 | Baltz; Richard H. | Biosynthetic genes for spinosyn insecticide production |
| WO1999061599A2 (en) | 1998-05-28 | 1999-12-02 | Kosan Biosciences, Inc. | Recombinant narbonolide polyketide synthase |
| NZ508326A (en) | 1998-06-18 | 2003-10-31 | Novartis Ag | A polyketide synthase and non ribosomal peptide synthase genes, isolated from a myxobacterium, necessary for synthesis of epothiones A and B |
| US6265202B1 (en) | 1998-06-26 | 2001-07-24 | Regents Of The University Of Minnesota | DNA encoding methymycin and pikromycin |
| MXPA01003376A (es) | 1998-10-02 | 2002-11-07 | Kosan Biosciences Inc | Enzimas policetido sintetasa y construcciones de acido desoxirribonucleico recombinante para las mismas. |
| JP2003512013A (ja) | 1998-10-29 | 2003-04-02 | コーサン バイオサイエンシーズ， インコーポレイテッド | 組換えオレアンドライドポリケチドシンターゼ |
| WO2000031247A2 (en) | 1998-11-20 | 2000-06-02 | Kosan Biosciences, Inc. | Recombinant methods and materials for producing epothilone and epothilone derivatives |
| US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| US7253001B2 (en) | 2002-03-19 | 2007-08-07 | Forskarpatent I Syd Ab | Metabolic engineering for improved xylose utilisation of Saccharomyces cerevisiae |
| WO2009013159A2 (en) | 2007-07-23 | 2009-01-29 | Dsm Ip Assets B.V. | Acetyl-coa producing enzymes in yeast |
| AU2009316660B2 (en) | 2008-11-19 | 2015-01-29 | Amrys, Inc. | Compositions and methods for the assembly of polynucleotides |
| JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
| MX2012001508A (es) | 2009-08-04 | 2013-05-30 | Evogene Ltd | Polinucleotidos y polipeptidos aislados, y metodos para utilizarlos para mejorar la tolerancia al estres abiotico, rendimiento, tasa de crecimiento, vigor, biomasa, contenido de aceite y/o eficacia en el uso de nitrogeno de las plantas. |
| JP5056897B2 (ja) | 2010-05-14 | 2012-10-24 | トヨタ自動車株式会社 | ２−ブタノールの製造方法及び２−ブタノール生産能を有する組換え微生物 |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| JP5387756B2 (ja) * | 2011-01-20 | 2014-01-15 | トヨタ自動車株式会社 | 組換え酵母及びこれを用いた物質生産方法 |
| BR112013027555A2 (pt) | 2011-04-29 | 2021-08-10 | Danisco Us Inc. | células recombinantes capazes de maior produção de isopreno, mevalonato e isoprenoides e método para produzir isopreno, mevalonato e isoprenoides |
| EP2546336A1 (en) * | 2011-07-11 | 2013-01-16 | DSM IP Assets B.V. | Yeast strains that consume uronic acids and produce fermentation products such as ethanol |
| EP2776571B1 (en) * | 2011-11-09 | 2017-04-12 | Amyris, Inc. | Production of acetyl-coenzyme a derived isoprenoids |
| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
-
2014
- 2014-03-14 JP JP2016502782A patent/JP6595449B2/ja active Active
- 2014-03-14 MX MX2015012365A patent/MX364748B/es active IP Right Grant
- 2014-03-14 EP EP14714149.3A patent/EP2971027B1/en active Active
- 2014-03-14 WO PCT/US2014/028421 patent/WO2014144135A2/en not_active Ceased
- 2014-03-14 MY MYPI2015703178A patent/MY171958A/en unknown
- 2014-03-14 CA CA2903053A patent/CA2903053C/en active Active
- 2014-03-14 AU AU2014227811A patent/AU2014227811C1/en active Active
- 2014-03-14 ES ES14714149T patent/ES2721920T3/es active Active
- 2014-03-14 US US14/214,062 patent/US9410214B2/en active Active
- 2014-03-14 CN CN201480025977.7A patent/CN105189772B/zh active Active
- 2014-03-14 KR KR1020157028637A patent/KR102159691B1/ko active Active
- 2014-03-14 BR BR112015023089A patent/BR112015023089A2/pt not_active Application Discontinuation
-
2015
- 2015-09-01 ZA ZA2015/06406A patent/ZA201506406B/en unknown
-
2019
- 2019-09-26 JP JP2019175333A patent/JP2019213558A/ja active Pending
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