BR112015023089A2 - célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa - Google Patents
célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coaInfo
- Publication number
- BR112015023089A2 BR112015023089A2 BR112015023089A BR112015023089A BR112015023089A2 BR 112015023089 A2 BR112015023089 A2 BR 112015023089A2 BR 112015023089 A BR112015023089 A BR 112015023089A BR 112015023089 A BR112015023089 A BR 112015023089A BR 112015023089 A2 BR112015023089 A2 BR 112015023089A2
- Authority
- BR
- Brazil
- Prior art keywords
- acetyl
- coa
- host cell
- isoprenoid
- producing
- Prior art date
Links
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 150000003505 terpenes Chemical class 0.000 title abstract 3
- 108010032776 glycerol-1-phosphatase Proteins 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- LIPOUNRJVLNBCD-UHFFFAOYSA-N acetyl dihydrogen phosphate Chemical compound CC(=O)OP(O)(O)=O LIPOUNRJVLNBCD-UHFFFAOYSA-N 0.000 abstract 2
- -1 acetyl-coa derivative compound Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 108700023175 Phosphate acetyltransferases Proteins 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 108010004621 phosphoketolase Proteins 0.000 abstract 1
- 229930001119 polyketide Natural products 0.000 abstract 1
- 125000000830 polyketide group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/02—Aldehyde-lyases (4.1.2)
- C12Y401/02009—Phosphoketolase (4.1.2.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/54—Acetic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03021—Glycerol-1-phosphatase (3.1.3.21)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361800356P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/028421 WO2014144135A2 (en) | 2013-03-15 | 2014-03-14 | Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015023089A2 true BR112015023089A2 (pt) | 2017-11-21 |
Family
ID=50391556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015023089A BR112015023089A2 (pt) | 2013-03-15 | 2014-03-14 | célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9410214B2 (https=) |
| EP (1) | EP2971027B1 (https=) |
| JP (2) | JP6595449B2 (https=) |
| KR (1) | KR102159691B1 (https=) |
| CN (1) | CN105189772B (https=) |
| AU (1) | AU2014227811C1 (https=) |
| BR (1) | BR112015023089A2 (https=) |
| CA (1) | CA2903053C (https=) |
| ES (1) | ES2721920T3 (https=) |
| MX (1) | MX364748B (https=) |
| MY (1) | MY171958A (https=) |
| WO (1) | WO2014144135A2 (https=) |
| ZA (1) | ZA201506406B (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014008278A2 (pt) | 2011-10-07 | 2017-04-18 | Danisco Us Inc | utilização de fosfocetolase na produção de mevalonato, precursores isoprenoides e isopreno |
| BR112015011544B1 (pt) | 2012-11-20 | 2022-08-16 | Lallemand Hungary Liquidity Management Llc | Microrganismo recombinante, composição compreendendo o mesmo, método de produção de etanol e co-cultura |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| US20160376600A1 (en) | 2013-11-25 | 2016-12-29 | Genomatica, Inc. | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol |
| EP4296364B1 (en) | 2013-12-03 | 2025-12-03 | Genomatica, Inc. | Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis |
| EP3741865B1 (en) * | 2014-09-18 | 2024-03-13 | Genomatica, Inc. | Non-natural microbial organisms with improved energetic efficiency |
| CN104372017B (zh) * | 2014-11-05 | 2017-06-30 | 中国科学院青岛生物能源与过程研究所 | 一种提高基因工程菌异戊二烯及其衍生物产量的方法及应用 |
| WO2017051930A1 (en) * | 2015-09-25 | 2017-03-30 | Ajinomoto Co., Inc. | Method of producing isoprenoid compound |
| KR102587444B1 (ko) | 2015-09-29 | 2023-10-11 | 킴벌리-클라크 월드와이드, 인크. | 미생물총의 건강한 균형을 유지하기 위한 상승 조성물 |
| GB201519088D0 (en) * | 2015-10-28 | 2015-12-09 | Metabogen Ab | The use of bacteria formulations |
| CA3003163A1 (en) | 2015-10-29 | 2017-05-04 | Senomyx, Inc. | High intensity sweeteners |
| US10612032B2 (en) | 2016-03-24 | 2020-04-07 | The Board Of Trustees Of The Leland Stanford Junior University | Inducible production-phase promoters for coordinated heterologous expression in yeast |
| EP3505618A4 (en) * | 2016-10-28 | 2020-04-22 | Sekisui Chemical Co., Ltd. | RECOMBINANT CELL AND METHOD FOR PRODUCING ISOPRENE OR TERPEN |
| US20200040347A1 (en) * | 2016-11-16 | 2020-02-06 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and Methods for Identifying and Expressing Gene Clusters |
| BR112019012306A2 (pt) * | 2016-12-16 | 2019-11-12 | Danisco Us Inc | polipeptídeos de fusão de fosfocetolase-fosfotransacetilase bifuncionais |
| EP3574105B1 (en) | 2017-01-25 | 2021-04-21 | Amyris Bio Products Portugal, Unipessoal, LDA | Co-production of a sesquiterpene and a carotenoid |
| MX389431B (es) | 2017-02-28 | 2025-03-20 | Kimberly Clark Co | Composicion sinergica para el mantenimiento del equilibrio saludable de la microflora. |
| CN110431224A (zh) * | 2017-03-13 | 2019-11-08 | 帝斯曼知识产权资产管理有限公司 | 锌双核簇转录调控因子缺陷型菌株 |
| US11060124B2 (en) | 2017-05-03 | 2021-07-13 | Firmenich Incorporated | Methods for making high intensity sweeteners |
| WO2018213349A1 (en) * | 2017-05-16 | 2018-11-22 | The Regents Of The University Of California | Methods and compositions for 3-hydroxypropionate production |
| WO2019030007A1 (en) | 2017-08-07 | 2019-02-14 | Total Raffinage Chimie | PROCESS FOR RECOVERING FERMENTATION PRODUCTS |
| US11103808B2 (en) | 2017-08-07 | 2021-08-31 | Amyris, Inc. | Process for recovering isoprenoids produced by microorganisms |
| JP2019041712A (ja) * | 2017-09-05 | 2019-03-22 | 株式会社デンソー | 組み換え体及びスクアレンの製造方法 |
| CA3075528A1 (en) | 2017-09-14 | 2019-03-21 | Lifemine Therapeutics, Inc. | Human therapeutic targets and modulators thereof |
| WO2019113387A1 (en) | 2017-12-07 | 2019-06-13 | Zymergen Inc. | Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation |
| JP2021506316A (ja) | 2017-12-21 | 2021-02-22 | ザイマージェン インコーポレイテッド | ネペタラクトールオキシドレダクターゼ、ネペタラクトールシンターゼ、及びネペタラクトンを産生する能力がある微生物 |
| PL3762499T3 (pl) * | 2018-03-06 | 2024-06-24 | Danisco Us Inc | Redukcja wytwarzania octanu przez drożdże wykazujące nadmierną ekspresję pab1 |
| CN112105726A (zh) * | 2018-03-06 | 2020-12-18 | 丹尼斯科美国公司 | 使用gcy1和dak1来增加酵母的乙醇生产的组合物和方法 |
| MX2021000053A (es) | 2018-07-12 | 2021-03-25 | Amyris Inc | Metodos para controlar velocidades de alimentacion de la fermentacion. |
| JP2022512931A (ja) | 2018-11-07 | 2022-02-07 | フィルメニッヒ インコーポレイテッド | 高甘味度甘味料の製造方法 |
| CA3118467A1 (en) | 2018-11-07 | 2020-05-14 | Firmenich Incorporated | Methods for making high intensity sweeteners |
| CN111378588A (zh) * | 2018-12-29 | 2020-07-07 | 中国科学院青岛生物能源与过程研究所 | 一种转化纤维素水解液合成法尼烯的基因工程菌及其应用 |
| MA55912A (fr) * | 2019-05-08 | 2022-03-16 | Auxolytic Ltd | Procédés de sélection auxotrophe |
| BR112022001859A2 (pt) * | 2019-08-01 | 2022-06-28 | Danisco Us Inc | Superexpressão de adh5p para produção de etanol aumentada por levedura |
| CN110628806B (zh) * | 2019-09-23 | 2021-09-21 | 华南理工大学 | 一种高产β-紫罗兰酮基因工程菌及其构建方法和应用 |
| CN111763662B (zh) * | 2019-11-29 | 2023-12-19 | 上海京新生物医药有限公司 | 酮还原酶及其在替格瑞洛中间体合成中的应用 |
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| US11905544B2 (en) | 2020-12-17 | 2024-02-20 | Debut Biotechnology, Inc. | Dehydratase variants with improved specific activity for the production of pyruvate from glycerate |
| US12006528B2 (en) | 2020-12-18 | 2024-06-11 | Debut Biotechnology, Inc. | Cell-free production of geranyl pyrophosphate from glycerol in a cell-free manufacturing system |
| US20220333118A1 (en) | 2021-04-13 | 2022-10-20 | Debut Biotechnology, Inc. | Flavonoid and anthocyanin bioproduction using microorganism hosts |
| CN113430215B (zh) * | 2021-06-03 | 2023-04-18 | 昆明理工大学 | 乙酰CoA合成酶基因RKACS1及其应用 |
| CN114480158B (zh) * | 2021-09-15 | 2023-02-03 | 安徽农业大学 | 一种戊糖片球菌及其在棉酚降解中的应用 |
| WO2023244843A1 (en) | 2022-06-16 | 2023-12-21 | Amyris, Inc. | HIGH pH METHODS AND COMPOSITIONS FOR CULTURING GENETICALLY MODIFIED HOST CELLS |
| NL2032683B1 (en) * | 2022-07-18 | 2024-01-26 | Sestina Bio Llc | Bioproduction of isoprenoids |
| CN115305226B (zh) * | 2022-09-22 | 2023-06-16 | 郑州轻工业大学 | 一株降解烟碱并产氢的抗辐射不动杆菌zj-22及其应用 |
| CN116926092B (zh) * | 2022-10-28 | 2024-04-26 | 昆明理工大学 | 一种泛酸激酶基因RkPank及其应用 |
| CN116064266B (zh) * | 2022-11-01 | 2024-06-14 | 四川大学 | 盐胁迫抗性增强的重组酿酒酵母菌及其构建方法与应用 |
| EP4649142A1 (en) | 2023-01-10 | 2025-11-19 | Amyris, Inc. | Production of canthaxanthin |
| CN121079426A (zh) | 2023-05-15 | 2025-12-05 | 帝斯曼知识产权资产管理有限公司 | 发酵过程中减少乳液形成的方法 |
| AR133254A1 (es) * | 2023-07-14 | 2025-09-10 | Danstar Ferment Ag | Aumento de la producción de acetil-coenzima a y productos derivados en levaduras |
| WO2025133860A1 (en) * | 2023-12-21 | 2025-06-26 | Danstar Ferment Ag | Increased production of acetyl-phosphate and products derived therefrom in yeasts |
| CN119639631B (zh) * | 2025-02-12 | 2025-05-23 | 云南省农业科学院农业环境资源研究所 | 一株草根围副伯克霍尔德氏菌及其菌剂与应用 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703009A (en) | 1983-03-08 | 1987-10-27 | Merck & Co., Inc. | RDNA cloning vector pVE1, deletion and hybrid mutants and recombinant derivatives thereof products and processes |
| DE3477936D1 (en) | 1983-03-08 | 1989-06-01 | Merck & Co Inc | Recombinant dna cloning vector pve1, deletion and hybrid mutants, and recombinant derivatives thereof, products and processes |
| US5272065A (en) | 1983-10-20 | 1993-12-21 | Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
| CA1340599C (en) | 1986-03-21 | 1999-06-22 | Karen Leigh Cox | Antibiotic-producing microorganisms |
| US5672497A (en) | 1986-03-21 | 1997-09-30 | Eli Lilly And Company | Method for increasing the antibiotic-producing ability of antibiotic-producing microorganisms |
| US5098837A (en) | 1988-06-07 | 1992-03-24 | Eli Lilly And Company | Macrolide biosynthetic genes for use in streptomyces and other organisms |
| US5149638A (en) | 1988-09-29 | 1992-09-22 | Eli Lilly And Company | Tylosin biosynthetic genes tylA, tylB and tylI |
| US5252474A (en) | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
| US5824513A (en) | 1991-01-17 | 1998-10-20 | Abbott Laboratories | Recombinant DNA method for producing erythromycin analogs |
| WO1993013663A1 (en) | 1992-01-17 | 1993-07-22 | Abbott Laboratories | Method of directing biosynthesis of specific polyketides |
| US6060234A (en) | 1991-01-17 | 2000-05-09 | Abbott Laboratories | Polyketide derivatives and recombinant methods for making same |
| JPH09504436A (ja) | 1993-11-02 | 1997-05-06 | メルク エンド カンパニー インコーポレーテッド | トリオールポリケチドシンターゼをコードするｄｎａ |
| US5716849A (en) | 1994-06-08 | 1998-02-10 | Novartis Finance Corporation | Genes for the biosynthesis of soraphen |
| CA2197524A1 (en) | 1996-02-22 | 1997-08-22 | Bradley Stuart Dehoff | Polyketide synthase genes |
| CA2197160C (en) | 1996-02-22 | 2007-05-01 | Stanley Gene Burgett | Platenolide synthase gene |
| ES2271973T3 (es) | 1996-08-20 | 2007-04-16 | Novartis Ag | Grupo de genes de la biosintesis de la rifamicina. |
| CN1174100C (zh) * | 1996-11-13 | 2004-11-03 | 纳幕尔杜邦公司 | 用重组生物体生产甘油的方法 |
| JP2001511349A (ja) | 1997-07-25 | 2001-08-14 | ヘキスト・マリオン・ルセル | Ｓａｃｃｈａｒｏｐｏｌｙｓｐｏｒａｅｒｙｔｈｒａｅａ及びＳｔｒｅｐｔｏｍｙｃｅｓａｎｔｉｂｉｏｔｉｃｕｓにおける６−デオキシヘキソースの生合成及び移送のための遺伝子 |
| US6090601A (en) | 1998-01-23 | 2000-07-18 | Kosan Bioscience | Sorangium polyketide synthase |
| US6143526A (en) | 1998-03-09 | 2000-11-07 | Baltz; Richard H. | Biosynthetic genes for spinosyn insecticide production |
| NZ509006A (en) | 1998-05-28 | 2003-09-26 | Kosan Biosciences Inc | Recombinant narbonolide polyketide synthase |
| NZ508326A (en) | 1998-06-18 | 2003-10-31 | Novartis Ag | A polyketide synthase and non ribosomal peptide synthase genes, isolated from a myxobacterium, necessary for synthesis of epothiones A and B |
| US6265202B1 (en) | 1998-06-26 | 2001-07-24 | Regents Of The University Of Minnesota | DNA encoding methymycin and pikromycin |
| NZ510819A (en) | 1998-10-02 | 2004-03-26 | Kosan Biosciences Inc | Polyketide synthase enzymes and recombinant DNA constructs therefor |
| JP2003512013A (ja) | 1998-10-29 | 2003-04-02 | コーサン バイオサイエンシーズ， インコーポレイテッド | 組換えオレアンドライドポリケチドシンターゼ |
| NZ511722A (en) | 1998-11-20 | 2004-05-28 | Kosan Biosciences Inc | Recombinant methods and materials for producing epothilone and epothilone derivatives |
| US7192751B2 (en) | 2001-12-06 | 2007-03-20 | The Regents Of The University Of California | Biosynthesis of amorpha-4,11-diene |
| US7253001B2 (en) | 2002-03-19 | 2007-08-07 | Forskarpatent I Syd Ab | Metabolic engineering for improved xylose utilisation of Saccharomyces cerevisiae |
| US20100248233A1 (en) | 2007-07-23 | 2010-09-30 | Dsm Ip Assets B.V. | Acetyl-coa producing enzymes in yeast |
| WO2010059763A1 (en) | 2008-11-19 | 2010-05-27 | Amyris Biotechnologies, Inc. | Compositions and methods for the assembly of polynucleotides |
| JP4760951B2 (ja) | 2009-05-08 | 2011-08-31 | トヨタ自動車株式会社 | ブタノール生産能を有する組換え微生物及びブタノールの製造方法 |
| WO2011015985A2 (en) | 2009-08-04 | 2011-02-10 | Evogene Ltd. | Polynucleotides and polypeptides for increasing desirable plant qualities |
| JP5056897B2 (ja) | 2010-05-14 | 2012-10-24 | トヨタ自動車株式会社 | ２−ブタノールの製造方法及び２−ブタノール生産能を有する組換え微生物 |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| CN103328631B (zh) * | 2011-01-20 | 2017-04-26 | 丰田自动车株式会社 | 重组酵母和使用该重组酵母的物质生产方法 |
| BR112013027555A2 (pt) * | 2011-04-29 | 2021-08-10 | Danisco Us Inc. | células recombinantes capazes de maior produção de isopreno, mevalonato e isoprenoides e método para produzir isopreno, mevalonato e isoprenoides |
| EP2546336A1 (en) * | 2011-07-11 | 2013-01-16 | DSM IP Assets B.V. | Yeast strains that consume uronic acids and produce fermentation products such as ethanol |
| CN104039974B (zh) * | 2011-11-09 | 2016-10-12 | 阿迈瑞斯公司 | 乙酰辅酶a衍生的类异戊二烯的生产 |
| US9163263B2 (en) | 2012-05-02 | 2015-10-20 | The Goodyear Tire & Rubber Company | Identification of isoprene synthase variants with improved properties for the production of isoprene |
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| AU2014227811B2 (en) | 2018-03-22 |
| JP6595449B2 (ja) | 2019-10-23 |
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| JP2019213558A (ja) | 2019-12-19 |
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| CA2903053C (en) | 2023-01-17 |
| ZA201506406B (en) | 2017-01-25 |
| WO2014144135A2 (en) | 2014-09-18 |
| AU2014227811A1 (en) | 2015-09-24 |
| MY171958A (en) | 2019-11-08 |
| MX2015012365A (es) | 2016-04-15 |
| WO2014144135A3 (en) | 2014-10-23 |
| CN105189772A (zh) | 2015-12-23 |
| EP2971027B1 (en) | 2019-01-30 |
| KR102159691B1 (ko) | 2020-09-24 |
| ES2721920T3 (es) | 2019-08-06 |
| US9410214B2 (en) | 2016-08-09 |
| US20140273144A1 (en) | 2014-09-18 |
| MX364748B (es) | 2019-05-06 |
| JP2016512047A (ja) | 2016-04-25 |
| EP2971027A2 (en) | 2016-01-20 |
| AU2014227811C1 (en) | 2018-09-27 |
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