|
US4444744A
(en)
|
1980-03-03 |
1984-04-24 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibodies to cell surface antigens
|
|
DE3407582A1
(de)
|
1984-03-01 |
1985-09-05 |
Dornier System Gmbh, 7990 Friedrichshafen |
Schaltungsanordnung fuer einen regelkreis
|
|
EP0282581A4
(en)
|
1986-09-19 |
1988-11-02 |
Scripps Clinic Res |
Monoclonal paratopic molecule directed to human ganglioside gd2.
|
|
US5591829A
(en)
|
1987-05-29 |
1997-01-07 |
Matsushita; Shuzo |
Antibodies modified with toxic substance
|
|
US5051364A
(en)
|
1989-02-16 |
1991-09-24 |
The Salk Institute For Biological Studies |
Anti-lipocortin-I and anti-lipocortin-II monoclonal antibodies
|
|
DE3909799A1
(de)
|
1989-03-24 |
1990-09-27 |
Behringwerke Ag |
Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
|
|
EP0491007B1
(en)
|
1989-09-08 |
1996-03-13 |
The Johns Hopkins University |
Structural alterations of the egf receptor gene in human gliomas
|
|
US5223253A
(en)
|
1989-09-28 |
1993-06-29 |
American Home Products Corporation |
Bovine vaccine compositions and method for preventing trichomonas infections using same
|
|
US5650489A
(en)
|
1990-07-02 |
1997-07-22 |
The Arizona Board Of Regents |
Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
|
|
GB2250993B
(en)
|
1990-11-21 |
1995-02-15 |
Inst Nat Sante Rech Med |
Stromelysin-3 and its application in the diagnosis and treatment of malignant breast cancer
|
|
US5750376A
(en)
|
1991-07-08 |
1998-05-12 |
Neurospheres Holdings Ltd. |
In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
|
|
MX9205293A
(es)
|
1991-09-20 |
1993-05-01 |
Syntex Sinergen Neuroscience J |
Factores neurotrofico derivado del glial
|
|
US5314992A
(en)
|
1991-11-25 |
1994-05-24 |
Trustees Of Dartmouth College |
Lipocortin-1 receptor protein and its uses
|
|
EP0642353A1
(en)
|
1992-05-14 |
1995-03-15 |
Oncologix, Inc. |
Treatment of vascular leakage syndrome and collagenase induced disease by administration of matrix metalloproteinase inhibitors
|
|
UA29466C2
(uk)
|
1993-01-14 |
2000-11-15 |
Канзер Рісерч Кампейн Технолоджі, Лтд |
Фармацевтична композиція з антипухлинною активністю
|
|
US5626862A
(en)
|
1994-08-02 |
1997-05-06 |
Massachusetts Institute Of Technology |
Controlled local delivery of chemotherapeutic agents for treating solid tumors
|
|
US5688773A
(en)
|
1994-08-17 |
1997-11-18 |
The General Hospital Corporation |
Method of selectively destroying neoplastic cells
|
|
US5985822A
(en)
|
1994-12-09 |
1999-11-16 |
The Scripps Research Institute |
Inhibition of glial cell proliferation with N-CAM homophilic peptides
|
|
US5756340A
(en)
|
1995-05-08 |
1998-05-26 |
The Regents Of The University Of California |
Insect control with multiple toxins
|
|
JP3809502B2
(ja)
|
1995-05-30 |
2006-08-16 |
二郎 有川 |
ハンタウィルス抗原蛋白質およびモノクローナル抗体
|
|
JPH0971599A
(ja)
|
1995-09-06 |
1997-03-18 |
Nippon Seibutsu Kagaku Kenkyusho |
鶏貧血ウイルス(cav)感染鶏血清と高い反応性を示すポリペプチド及びこのポリペプチドに対する抗体、鶏貧血ウイルス感染の診断法及びワクチン
|
|
US6667156B2
(en)
|
1995-12-27 |
2003-12-23 |
Uab Research Foundation |
Diagnosis and treatment of neuroectodermal tumors
|
|
US5905027A
(en)
|
1995-12-27 |
1999-05-18 |
Uab Research Foundation |
Method of diagnosing and treating gliomas
|
|
WO1997043301A2
(en)
*
|
1996-05-10 |
1997-11-20 |
Novartis Ag |
Identification of members of combinatorial libraries by mass spectrometry
|
|
US6130101A
(en)
|
1997-09-23 |
2000-10-10 |
Molecular Probes, Inc. |
Sulfonated xanthene derivatives
|
|
AU748250B2
(en)
|
1997-12-05 |
2002-05-30 |
Kyogo Itoh |
Tumor antigen peptide derivatives
|
|
GB9809776D0
(en)
*
|
1998-05-07 |
1998-07-08 |
Nycomed Imaging As |
Method
|
|
AU5197599A
(en)
|
1998-08-12 |
2000-03-06 |
Daiichi Pure Chemicals Co., Ltd. |
Fluorescent labelling reagents
|
|
US6703381B1
(en)
|
1998-08-14 |
2004-03-09 |
Nobex Corporation |
Methods for delivery therapeutic compounds across the blood-brain barrier
|
|
DE69912444T3
(de)
*
|
1998-08-25 |
2010-05-06 |
University Of Washington, Seattle |
Schnelle quantitative analyse von proteinen oder proteinfunktionen in komplexen gemischen
|
|
US6214986B1
(en)
|
1998-10-07 |
2001-04-10 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of bcl-x expression
|
|
US6629040B1
(en)
*
|
1999-03-19 |
2003-09-30 |
University Of Washington |
Isotope distribution encoded tags for protein identification
|
|
SE9901387D0
(sv)
|
1999-04-19 |
1999-04-19 |
Astra Ab |
New pharmaceutical foromaulations
|
|
US6849714B1
(en)
|
1999-05-17 |
2005-02-01 |
Conjuchem, Inc. |
Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
|
|
US6767635B1
(en)
|
1999-09-14 |
2004-07-27 |
Biomedical Apherese Systeme Gmbh |
Magnetic nanoparticles having biochemical activity, method for the production thereof and their use
|
|
AUPQ339899A0
(en)
*
|
1999-10-13 |
1999-11-04 |
University Of Queensland, The |
Novel molecules
|
|
AU4305101A
(en)
|
1999-11-22 |
2001-06-04 |
Research Foundation Of The State University Of New York, The |
Magnetic nanoparticles for selective therapy
|
|
DE10020376A1
(de)
|
2000-04-26 |
2001-11-08 |
Inst Zelltechnologie E V |
Dynamische Marker
|
|
CA2427858A1
(en)
|
2000-11-03 |
2002-05-10 |
University Of Vermont And State Agricultural College |
Compositions for inhibiting grb7
|
|
US20020077921A1
(en)
|
2000-12-15 |
2002-06-20 |
Paul-David Morrison |
Method and apparatus for an interactive catalog
|
|
WO2002069896A2
(en)
|
2001-03-01 |
2002-09-12 |
Northwest Hospital |
Connexin enhances chemotherapy-induced apoptosis in human cancer cells inhibiting tumor cell proliferation
|
|
WO2003008583A2
(en)
|
2001-03-02 |
2003-01-30 |
Sagres Discovery |
Novel compositions and methods for cancer
|
|
WO2003000203A2
(en)
|
2001-06-26 |
2003-01-03 |
Uab Research Foundation |
Chlorotoxin inhibition of cell invasion, cancer metastasis, angiogenesis and tissue remodeling
|
|
GB0115581D0
(en)
*
|
2001-06-26 |
2001-08-15 |
Glaxo Group Ltd |
Method of mass spectometry
|
|
WO2003029462A1
(en)
|
2001-09-27 |
2003-04-10 |
Pieris Proteolab Ag |
Muteins of human neutrophil gelatinase-associated lipocalin and related proteins
|
|
US6972326B2
(en)
|
2001-12-03 |
2005-12-06 |
Molecular Probes, Inc. |
Labeling of immobilized proteins using dipyrrometheneboron difluoride dyes
|
|
WO2003066663A2
(en)
|
2002-02-04 |
2003-08-14 |
Auburn University |
Peptides for recognition and targeting of glial cell tumors
|
|
US20030232013A1
(en)
|
2002-02-22 |
2003-12-18 |
Gary Sieckman |
Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides
|
|
WO2003101474A1
(en)
|
2002-05-31 |
2003-12-11 |
Transmolecular, Inc. |
Combination chemotherapy with chlorotoxin
|
|
US20060088899A1
(en)
|
2002-05-31 |
2006-04-27 |
Alvarez Vernon L |
Combination chemotherapy with chlorotoxin
|
|
US7563600B2
(en)
*
|
2002-09-12 |
2009-07-21 |
Combimatrix Corporation |
Microarray synthesis and assembly of gene-length polynucleotides
|
|
US7560160B2
(en)
|
2002-11-25 |
2009-07-14 |
Materials Modification, Inc. |
Multifunctional particulate material, fluid, and composition
|
|
US20040101822A1
(en)
|
2002-11-26 |
2004-05-27 |
Ulrich Wiesner |
Fluorescent silica-based nanoparticles
|
|
CA2519361A1
(en)
*
|
2003-03-21 |
2004-10-07 |
Schering Corporation |
Method of screening for target ligands
|
|
CN1791671A
(zh)
*
|
2003-03-21 |
2006-06-21 |
先灵公司 |
靶配体的筛选方法
|
|
EP1639090A4
(en)
|
2003-06-09 |
2008-04-16 |
Univ Michigan |
COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
|
|
DE10328251A1
(de)
|
2003-06-24 |
2005-01-13 |
Toximed Gmbh |
Pharmazeutischer Wirkstoff
|
|
WO2005053611A2
(en)
|
2003-11-26 |
2005-06-16 |
Transmolecular, Inc. |
Treatment of phosphatidylinositol phospholipid disorders
|
|
DE602004020570D1
(de)
*
|
2003-12-18 |
2009-05-28 |
Biomethodes |
Verfahren zur ortspezifischen Massenmutagenese
|
|
DE602005019728D1
(de)
|
2004-04-06 |
2010-04-15 |
Transmolecular Inc |
Diagnose und behandlung von myeloid- und lymphoidzellenkrebs mit chlorotoxin oder derivat
|
|
US20080153746A1
(en)
|
2004-04-06 |
2008-06-26 |
Transmolecular, Inc. |
Diagnosis and Treatment of Myeloid and Lymphoid Cell Cancers
|
|
CA2565701A1
(en)
|
2004-05-06 |
2005-11-17 |
Jonathan M. Barasch |
Ngal for reduction and amelioration of ischemic and nephrotoxic injuries
|
|
JP2008507280A
(ja)
|
2004-07-21 |
2008-03-13 |
アンブレツクス・インコーポレイテツド |
非天然コードアミノ酸を用いた生合成ポリペプチド
|
|
WO2006036928A2
(en)
*
|
2004-09-27 |
2006-04-06 |
Wayne State University |
Inhibitors of matrix metalloproteinases to treat neurological disorders
|
|
GB0422901D0
(en)
*
|
2004-10-14 |
2004-11-17 |
Ares Trading Sa |
Lipocalin protein
|
|
KR100681763B1
(ko)
|
2005-02-28 |
2007-02-15 |
재단법인 목암생명공학연구소 |
인간 리포칼린 2를 유효성분으로 포함하는 암 전이 억제용약학적 조성물, 이를 이용한 암 전이 억제 방법
|
|
GB0504767D0
(en)
*
|
2005-03-08 |
2005-04-13 |
Ares Trading Sa |
Lipocalin protein
|
|
US7462446B2
(en)
|
2005-03-18 |
2008-12-09 |
University Of Washington |
Magnetic nanoparticle compositions and methods
|
|
US20070037232A1
(en)
|
2005-03-31 |
2007-02-15 |
Barasch Jonathan M |
Detection of NGAL in chronic renal disease
|
|
EP1871911A2
(en)
|
2005-04-07 |
2008-01-02 |
Chiron Corporation |
Cancer-related genes (prlr)
|
|
WO2006110582A1
(en)
|
2005-04-08 |
2006-10-19 |
Xcyte Therapies, Inc. |
Compositions and methods for the treatment of burns and sepsis
|
|
US7833979B2
(en)
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
|
ATE502048T1
(de)
|
2005-04-22 |
2011-04-15 |
Univ Washington |
Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs
|
|
MX2008002149A
(es)
|
2005-08-18 |
2008-04-22 |
Ambrx Inc |
Composiciones de arnt y sus usos.
|
|
EP2147927A3
(en)
|
2006-03-31 |
2010-09-01 |
Transmolecular, Inc. |
Use of 131i-tm-601 for the diagnosis and treatment of gliomas
|
|
EP2029157A4
(en)
|
2006-05-19 |
2009-11-18 |
Georgia Tech Res Inst |
ABC TRANSPORTERLIGAND
|
|
CN100564517C
(zh)
|
2006-09-21 |
2009-12-02 |
武汉大学 |
一种蝎抗神经胶质瘤肽及其制备方法和应用
|
|
CN101003788A
(zh)
|
2006-09-21 |
2007-07-25 |
武汉大学 |
一种蝎抗肿瘤转移肽及其制备方法和应用
|
|
PE20081140A1
(es)
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
|
ATE502114T1
(de)
|
2007-06-21 |
2011-04-15 |
Univ Muenchen Tech |
Biologisch aktive proteine mit erhöhter in-vivo- und/oder in-vitro-stabilität
|
|
US20090004105A1
(en)
|
2007-06-27 |
2009-01-01 |
Zhen Cheng |
Molecular imaging of matrix metalloproteinase expression using labeled chlorotoxin
|
|
CA2696303A1
(en)
|
2007-08-07 |
2009-02-12 |
Transmolecular, Inc. |
Chlorotoxins as drug carriers
|
|
US20110283260A1
(en)
|
2007-08-31 |
2011-11-17 |
Iosemantics, Llc |
Quality assurance tools for use with source code and a semantic model
|
|
EP2211913A4
(en)
|
2007-10-12 |
2010-12-22 |
Transmolecular Inc |
SYSTEMIC ADMINISTRATION OF CHLOROTOXIN AGENTS FOR THE DIAGNOSIS AND TREATMENT OF TUMORS
|
|
CA2702611A1
(en)
|
2007-10-19 |
2009-04-23 |
Abbott Laboratories |
Immunoassays and kits for the detection of ngal
|
|
US8846036B2
(en)
|
2007-10-19 |
2014-09-30 |
Abbott Laboratories |
Antibodies that bind to mammalian NGAL and uses thereof
|
|
US20090123970A1
(en)
|
2007-10-19 |
2009-05-14 |
Abbott Laboratories |
Glycosylated mammalian ngal and use thereof
|
|
US20090269777A1
(en)
|
2007-10-19 |
2009-10-29 |
Abbott Laboratories |
Immunoassays and kits for the detection of ngal
|
|
US20090124022A1
(en)
|
2007-10-19 |
2009-05-14 |
Abbott Laboratories |
Antibodies that bind to mammalian ngal and uses thereof
|
|
US20090176274A1
(en)
|
2007-10-19 |
2009-07-09 |
Abbott Laboratories |
Glycosylated mammalian ngal and use thereof
|
|
US20090123946A1
(en)
|
2007-10-19 |
2009-05-14 |
Abbott Laboratories |
Immunoassays and kits for the detection of ngal
|
|
CN101910845A
(zh)
|
2007-11-15 |
2010-12-08 |
比奥波托诊断股份公司 |
个体分子形式的生物标志的诊断用途
|
|
ES2658852T3
(es)
|
2008-01-18 |
2018-03-12 |
Visen Medical, Inc. |
Agentes de imaginología fluorescentes
|
|
US9308239B2
(en)
|
2008-02-26 |
2016-04-12 |
The Penn State Research Foundation |
Methods and compositions for treatment of retinoid-responsive conditions
|
|
US8093060B2
(en)
|
2008-02-28 |
2012-01-10 |
Canon Kabushiki Kaisha |
Multisite phosphorylated peptide (protein) recognizing compound and detection method, imaging method, alzheimer's disease diagnosing method and reagent kit using the same
|
|
CN102026671B
(zh)
|
2008-03-14 |
2014-09-03 |
Visen医药公司 |
整联蛋白靶向试剂及使用其的体内和体外成像方法
|
|
CN102056617A
(zh)
|
2008-03-20 |
2011-05-11 |
特兰斯莫莱库拉公司 |
血管生成的抑制
|
|
GB0807831D0
(en)
|
2008-04-29 |
2008-06-04 |
Cambridge Entpr Ltd |
Agents for imaging cell death
|
|
CN101270158B
(zh)
|
2008-04-30 |
2010-12-22 |
武汉大学 |
一种靶向抗神经胶质瘤蛋白及制备方法和用途
|
|
US8227439B2
(en)
|
2008-05-15 |
2012-07-24 |
Morphotek, Inc. |
Treatment of metastatic tumors
|
|
JP2009300110A
(ja)
|
2008-06-10 |
2009-12-24 |
Olympus Corp |
移植細胞の光学的検出方法又はイメージング方法
|
|
JP5711118B2
(ja)
|
2008-06-24 |
2015-04-30 |
テクニッシュ ウニヴェルジテート ミュンヘン |
所与の標的に対してアフィニティーを有するhNGALおよび類縁タンパク質のムテイン
|
|
US20100098637A1
(en)
|
2008-09-23 |
2010-04-22 |
The Regents Of The University Of Michigan |
Dye-loaded nanoparticle
|
|
CN101381405B
(zh)
|
2008-09-24 |
2011-07-27 |
武汉摩尔生物科技有限公司 |
基因工程肿瘤靶向kct-w1多肽及制备方法和用途
|
|
JP2010085108A
(ja)
|
2008-09-29 |
2010-04-15 |
Nano Factory:Kk |
生体光イメージング用プローブ
|
|
US20100105150A1
(en)
|
2008-10-24 |
2010-04-29 |
Abbott Laboratories |
Isolated human autoantibodies to neutrophil gelatinase-associated lipocalin (ngal) and methods and kits for the detection of human autoantibodies to ngal
|
|
US20100331650A1
(en)
*
|
2009-06-25 |
2010-12-30 |
Roche Diagnostics Operations, Inc. |
Episodic blood glucose monitoring system with an interactive graphical user interface and methods thereof
|
|
CN102791827B
(zh)
|
2009-11-09 |
2016-11-16 |
华盛顿大学商业化中心 |
官能化发色聚合物点及其生物共轭体
|
|
CN101921769B
(zh)
|
2010-01-11 |
2012-07-25 |
山西大学 |
一种重组腺病毒及其制备方法和应用
|
|
WO2011094671A2
(en)
|
2010-01-29 |
2011-08-04 |
The Uab Research Foundation |
N-terminally conjugated polypeptides for targeted therapy and diagnosis
|
|
JP5858932B2
(ja)
|
2010-02-04 |
2016-02-10 |
モルフォテック, インコーポレイテッド |
クロロトキシンポリペプチドおよびコンジュゲートならびにその使用
|
|
CN101824084A
(zh)
|
2010-04-08 |
2010-09-08 |
山西大学 |
靶向性抗胶质瘤蛋白质及其应用
|
|
JP2013532126A
(ja)
|
2010-05-11 |
2013-08-15 |
フレッド ハッチンソン キャンサー リサーチ センター |
クロロトキシン変異体、コンジュゲート、およびそれらを使用する方法
|
|
NZ606584A
(en)
*
|
2010-08-16 |
2014-10-31 |
Pieris Ag |
Binding proteins for hepcidin
|
|
EP2638173B1
(en)
*
|
2010-11-08 |
2019-06-19 |
The Board of Trustees of The Leland Stanford Junior University |
Fusion proteins comprising an engineered knottin peptide and uses thereof
|
|
EP3270407B1
(en)
*
|
2010-12-28 |
2021-07-07 |
Quest Diagnostics Investments LLC |
Quantitation of insulin by mass spectrometry
|
|
DK2748357T3
(en)
|
2011-09-07 |
2018-07-16 |
X Chem Inc |
Methods for labeling DNA-encoded libraries
|
|
CN105008393A
(zh)
|
2012-12-10 |
2015-10-28 |
弗莱德哈钦森癌症研究中心 |
用于筛选的方法
|