JP2016501191A5 - - Google Patents
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- JP2016501191A5 JP2016501191A5 JP2015542020A JP2015542020A JP2016501191A5 JP 2016501191 A5 JP2016501191 A5 JP 2016501191A5 JP 2015542020 A JP2015542020 A JP 2015542020A JP 2015542020 A JP2015542020 A JP 2015542020A JP 2016501191 A5 JP2016501191 A5 JP 2016501191A5
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- JP
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- Prior art keywords
- alkyl
- pharmaceutically acceptable
- acceptable salt
- stereoisomer
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 C*(*)C(C=C1)=**(*)C1=O Chemical compound C*(*)C(C=C1)=**(*)C1=O 0.000 description 8
- WMCIAMZXTMRTEN-UHFFFAOYSA-N CC(C=C1)=NN(C)C1=O Chemical compound CC(C=C1)=NN(C)C1=O WMCIAMZXTMRTEN-UHFFFAOYSA-N 0.000 description 1
- HDCAHRAHYJJDSU-UHFFFAOYSA-N Cc1cnc(NC)nc1 Chemical compound Cc1cnc(NC)nc1 HDCAHRAHYJJDSU-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261725913P | 2012-11-13 | 2012-11-13 | |
| US61/725,913 | 2012-11-13 | ||
| PCT/US2013/069729 WO2014078323A1 (en) | 2012-11-13 | 2013-11-12 | N-pyrrolidinyl, n'-pyrazolyl- urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017206051A Division JP6482629B2 (ja) | 2012-11-13 | 2017-10-25 | Ｔｒｋａキナーゼ阻害剤としてのｎ−ピロリジニル、ｎ’−ピラゾリル尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016501191A JP2016501191A (ja) | 2016-01-18 |
| JP2016501191A5 true JP2016501191A5 (enExample) | 2016-12-01 |
| JP6316834B2 JP6316834B2 (ja) | 2018-04-25 |
Family
ID=49667600
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015542020A Active JP6316834B2 (ja) | 2012-11-13 | 2013-11-12 | Ｔｒｋａキナーゼ阻害剤としてのｎ−ピロリジニル、ｎ’−ピラゾリル尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
| JP2017206051A Active JP6482629B2 (ja) | 2012-11-13 | 2017-10-25 | Ｔｒｋａキナーゼ阻害剤としてのｎ−ピロリジニル、ｎ’−ピラゾリル尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
| JP2019022674A Pending JP2019081786A (ja) | 2012-11-13 | 2019-02-12 | Ｔｒｋａキナーゼ阻害剤としてのｎ−ピロリジニル、ｎ’−ピラゾリル尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017206051A Active JP6482629B2 (ja) | 2012-11-13 | 2017-10-25 | Ｔｒｋａキナーゼ阻害剤としてのｎ−ピロリジニル、ｎ’−ピラゾリル尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
| JP2019022674A Pending JP2019081786A (ja) | 2012-11-13 | 2019-02-12 | Ｔｒｋａキナーゼ阻害剤としてのｎ−ピロリジニル、ｎ’−ピラゾリル尿素、チオ尿素、グアニジン、およびシアノグアニジン化合物 |
Country Status (32)
Families Citing this family (60)
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| TWI876442B (zh) | 2017-10-10 | 2025-03-11 | 美商絡速藥業公司 | 6-(2-羥基-2-甲基丙氧基)-4-(6-(6-((6-甲氧基吡啶-3-基)甲基)-3,6-二氮雜雙環[3.1.1]庚-3-基)吡啶-3-基)吡唑并[1,5-a]吡啶-3-甲腈之調配物 |
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| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
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