JP2015528814A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015528814A5 JP2015528814A5 JP2015524805A JP2015524805A JP2015528814A5 JP 2015528814 A5 JP2015528814 A5 JP 2015528814A5 JP 2015524805 A JP2015524805 A JP 2015524805A JP 2015524805 A JP2015524805 A JP 2015524805A JP 2015528814 A5 JP2015528814 A5 JP 2015528814A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- group
- optionally substituted
- cancer
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 24
- 206010028980 Neoplasm Diseases 0.000 claims 8
- 201000011510 cancer Diseases 0.000 claims 8
- 125000002947 alkylene group Chemical group 0.000 claims 7
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- 238000000034 method Methods 0.000 claims 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 238000003745 diagnosis Methods 0.000 claims 6
- 125000004432 carbon atom Chemical group C* 0.000 claims 4
- 238000002428 photodynamic therapy Methods 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 206010017533 Fungal infection Diseases 0.000 claims 2
- 208000031888 Mycoses Diseases 0.000 claims 2
- 208000036142 Viral infection Diseases 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000000732 arylene group Chemical group 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 125000002993 cycloalkylene group Chemical group 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 125000001475 halogen functional group Chemical group 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- 125000000547 substituted alkyl group Chemical group 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 125000001188 haloalkyl group Chemical group 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- RBEAYBQHKMZUIC-UHFFFAOYSA-N CC(C(O)=O)OC(CCC(CN)=O)=O Chemical compound CC(C(O)=O)OC(CCC(CN)=O)=O RBEAYBQHKMZUIC-UHFFFAOYSA-N 0.000 description 1
- PBLXLODXZMRGEN-UHFFFAOYSA-N NCC(CCC(O)OCCC(O)=O)=O Chemical compound NCC(CCC(O)OCCC(O)=O)=O PBLXLODXZMRGEN-UHFFFAOYSA-N 0.000 description 1
- CYUFWQITJUHRPK-UHFFFAOYSA-N NCC(CCC(OC(C(O)=O)(F)F)=O)=O Chemical compound NCC(CCC(OC(C(O)=O)(F)F)=O)=O CYUFWQITJUHRPK-UHFFFAOYSA-N 0.000 description 1
- YHADLDPGTIWYGF-UHFFFAOYSA-N NCC(CCC(OCC(O)=O)=O)=O Chemical compound NCC(CCC(OCC(O)=O)=O)=O YHADLDPGTIWYGF-UHFFFAOYSA-N 0.000 description 1
- QFCHWNKQKYZMIC-UHFFFAOYSA-N NCC(CCC(OCCCC(O)=O)=O)=O Chemical compound NCC(CCC(OCCCC(O)=O)=O)=O QFCHWNKQKYZMIC-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12179277.4 | 2012-08-03 | ||
| EP12179277 | 2012-08-03 | ||
| EP12197305 | 2012-12-14 | ||
| EP12197305.1 | 2012-12-14 | ||
| PCT/EP2013/066317 WO2014020164A1 (en) | 2012-08-03 | 2013-08-02 | Compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015528814A JP2015528814A (ja) | 2015-10-01 |
| JP2015528814A5 true JP2015528814A5 (enExample) | 2016-09-08 |
| JP6280117B2 JP6280117B2 (ja) | 2018-02-14 |
Family
ID=48948407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015524805A Active JP6280117B2 (ja) | 2012-08-03 | 2013-08-02 | 化合物 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9249086B2 (enExample) |
| EP (1) | EP2880012B1 (enExample) |
| JP (1) | JP6280117B2 (enExample) |
| KR (1) | KR102180174B1 (enExample) |
| CN (1) | CN104661994B (enExample) |
| AU (1) | AU2013298525B2 (enExample) |
| BR (1) | BR112015002390B1 (enExample) |
| CA (1) | CA2880422C (enExample) |
| CL (1) | CL2015000233A1 (enExample) |
| ES (1) | ES2908080T3 (enExample) |
| IL (1) | IL236965B (enExample) |
| IN (1) | IN2015DN00837A (enExample) |
| MX (1) | MX364940B (enExample) |
| NZ (1) | NZ629914A (enExample) |
| RU (1) | RU2635563C2 (enExample) |
| SG (1) | SG11201500805VA (enExample) |
| WO (1) | WO2014020164A1 (enExample) |
| ZA (1) | ZA201500778B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112016014073A2 (pt) | 2013-12-20 | 2017-08-08 | Galderma Res & Dev | Tratamento fotodinâmico de pulso de pele fotodanificada |
| EP4119539A1 (en) * | 2015-09-23 | 2023-01-18 | XWPharma Ltd. | Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof |
| DK3389716T3 (da) * | 2015-12-17 | 2022-04-11 | Photocure Asa | Fremgangsmåde til fotodynamisk terapi (pdt) for blærekræft |
| GB201522309D0 (en) * | 2015-12-17 | 2016-02-03 | Photocure Asa | Use |
| GB201522398D0 (en) | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| CN112010772A (zh) | 2016-01-26 | 2020-12-01 | 赵鸣 | 5-氨基酮戊酸及其衍生物的盐化合物和应用 |
| FI3641882T3 (fi) * | 2017-06-21 | 2023-12-14 | Photocure Asa | Menetelmä nestemäisen farmaseuttisen koostumuksen valmistamiseksi ja laite käytettäväksi sellaisessa menetelmässä |
| IL285384B2 (en) | 2019-02-13 | 2024-11-01 | Alpheus Medical Inc | Non-invasive sonodynamic therapy |
| WO2020243319A1 (en) | 2019-05-29 | 2020-12-03 | Sonalasense, Inc. | Sonosensitization |
| WO2022032283A2 (en) | 2020-08-07 | 2022-02-10 | Alpheus Medical, Inc. | Ultrasound arrays for enhanced sonodynamic therapy for treating cancer |
| EP4676462A1 (en) | 2023-03-07 | 2026-01-14 | Photocure ASA | Therapy for bladder cancer |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07188133A (ja) | 1993-12-27 | 1995-07-25 | Asahi Chem Ind Co Ltd | δ−アミノレブリン酸またはその同族体の製造法 |
| WO1996028412A1 (en) * | 1995-03-10 | 1996-09-19 | Photocure As | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| US6992107B1 (en) | 1995-03-10 | 2006-01-31 | Photocure Asa | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy |
| US7530461B2 (en) | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| US6492420B2 (en) | 1995-03-10 | 2002-12-10 | Photocure As | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| JPH1112197A (ja) | 1997-06-18 | 1999-01-19 | Cosmo Sogo Kenkyusho:Kk | 悪性腫瘍診断剤及び治療剤 |
| GB0018528D0 (en) | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| DE10202487A1 (de) | 2002-01-23 | 2003-07-31 | Photonamic Gmbh & Co Kg | Dermales Applikationssystem für Aminolävulinsäure-Derivate |
| DE10312659A1 (de) | 2003-03-21 | 2004-10-07 | Universität Regensburg | 5-Aminolävulinsäurederivate und ihre Verwendung |
| GB0406917D0 (en) | 2004-03-26 | 2004-04-28 | Photocure Asa | Compounds |
| JP4417865B2 (ja) | 2004-03-30 | 2010-02-17 | コスモ石油株式会社 | ５−アミノレブリン酸リン酸塩、その製造方法及びその用途 |
| JP4719483B2 (ja) | 2004-03-30 | 2011-07-06 | コスモ石油株式会社 | ５−アミノレブリン酸スルホン酸塩の製造方法 |
| ES2355978T3 (es) * | 2004-03-30 | 2011-04-01 | Cosmo Oil Co., Ltd. | Sal de fosfato de ácido 5-aminolevulinico, proceso para producir la misma y uso de la misma. |
| GB0424833D0 (en) * | 2004-11-10 | 2004-12-15 | Photocure Asa | Method |
| JP5404995B2 (ja) | 2006-08-10 | 2014-02-05 | コスモ石油株式会社 | 植物のポリフェノール増量剤 |
| JP5039389B2 (ja) | 2007-02-02 | 2012-10-03 | コスモ石油株式会社 | ホップのアルファ酸又はホップオイル含量向上剤 |
| PT2130435E (pt) | 2007-03-30 | 2015-11-30 | Cosmo Ala Co Ltd | Agente para melhorar a resistência de plantas a bases e método para melhorar a resistência de plantas a bases |
| JP4705616B2 (ja) | 2007-07-20 | 2011-06-22 | コスモ石油株式会社 | 植物における金属成分の吸収向上剤 |
| GB0724279D0 (en) * | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| CA2709274A1 (en) * | 2007-12-14 | 2009-06-25 | Photoderma Sa | Novel compounds useful in therapeutic and cosmetic methods |
| ES2822122T3 (es) | 2008-04-22 | 2021-04-29 | Sbi Pharmaceuticals Co Ltd | Método de detección del cáncer de vejiga |
| WO2009139106A1 (ja) | 2008-05-13 | 2009-11-19 | コスモ石油株式会社 | 芝草の品質向上剤 |
| JP5276894B2 (ja) | 2008-05-13 | 2013-08-28 | コスモ石油株式会社 | イネの健苗育成向上剤 |
| JP5323539B2 (ja) | 2009-03-11 | 2013-10-23 | コスモ石油株式会社 | 農作物の収穫部位の収量向上剤 |
-
2013
- 2013-08-02 EP EP13745829.5A patent/EP2880012B1/en active Active
- 2013-08-02 BR BR112015002390-8A patent/BR112015002390B1/pt active IP Right Grant
- 2013-08-02 CA CA2880422A patent/CA2880422C/en active Active
- 2013-08-02 US US14/419,125 patent/US9249086B2/en active Active
- 2013-08-02 NZ NZ629914A patent/NZ629914A/en unknown
- 2013-08-02 JP JP2015524805A patent/JP6280117B2/ja active Active
- 2013-08-02 IN IN837DEN2015 patent/IN2015DN00837A/en unknown
- 2013-08-02 AU AU2013298525A patent/AU2013298525B2/en active Active
- 2013-08-02 MX MX2015001374A patent/MX364940B/es active IP Right Grant
- 2013-08-02 KR KR1020157003692A patent/KR102180174B1/ko active Active
- 2013-08-02 WO PCT/EP2013/066317 patent/WO2014020164A1/en not_active Ceased
- 2013-08-02 SG SG11201500805VA patent/SG11201500805VA/en unknown
- 2013-08-02 CN CN201380048873.3A patent/CN104661994B/zh active Active
- 2013-08-02 RU RU2015104830A patent/RU2635563C2/ru active
- 2013-08-02 ES ES13745829T patent/ES2908080T3/es active Active
-
2015
- 2015-01-28 IL IL236965A patent/IL236965B/en active IP Right Grant
- 2015-01-30 CL CL2015000233A patent/CL2015000233A1/es unknown
- 2015-02-03 ZA ZA2015/00778A patent/ZA201500778B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015528814A5 (enExample) | ||
| RU2015104830A (ru) | Соединения | |
| CY1124117T1 (el) | Ετεροκυκλικες αλκυνυλοβενζολικες ενωσεις και ιατρικες συνθεσεις και χρησεις αυτων | |
| JP2015508103A5 (enExample) | ||
| JP2015500843A5 (enExample) | ||
| JP2016503797A5 (enExample) | ||
| JP2016503799A5 (enExample) | ||
| JP2016537382A5 (enExample) | ||
| JP2013510120A5 (enExample) | ||
| JP2010524947A5 (enExample) | ||
| JP2014508804A5 (enExample) | ||
| JP2006526646A5 (enExample) | ||
| JP2016506960A5 (enExample) | ||
| RU2015118647A (ru) | Аминопиримидиновые соединения в качестве ингибиторов содержащих т790м мутантных egfr | |
| JP2016040288A5 (enExample) | ||
| CN107427516B8 (zh) | 7-苄基-4-(2-甲基苄基)-2,4,6,7,8,9-六氢咪唑并[1,2-a]吡啶并[3,4-e]嘧啶-5(1h)-酮、其类似物、及其盐、以及它们用于治疗的方法 | |
| JP2019522055A5 (enExample) | ||
| JP2013537203A5 (enExample) | ||
| JP2012140458A5 (enExample) | ||
| JP2017529357A5 (enExample) | ||
| JP2013102146A5 (ja) | 化合物 | |
| JP2015501833A5 (enExample) | ||
| JP2017517538A5 (enExample) | ||
| JP2012513416A5 (enExample) | ||
| JP2014526533A5 (enExample) |