CN104661994B - 化合物 - Google Patents

化合物 Download PDF

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Publication number
CN104661994B
CN104661994B CN201380048873.3A CN201380048873A CN104661994B CN 104661994 B CN104661994 B CN 104661994B CN 201380048873 A CN201380048873 A CN 201380048873A CN 104661994 B CN104661994 B CN 104661994B
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compound
group
amino
pharmaceutically acceptable
product
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Chinese (zh)
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CN104661994A (zh
Inventor
J·E·布伦登
C·B·沙尔诺克
阿斯拉克·戈达尔
乔·克拉韦内斯
N·O·尼尔森
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Photocure ASA
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Photocure ASA
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/00615-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201380048873.3A 2012-08-03 2013-08-02 化合物 Active CN104661994B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12179277 2012-08-03
EP12179277.4 2012-08-03
EP12197305 2012-12-14
EP12197305.1 2012-12-14
PCT/EP2013/066317 WO2014020164A1 (en) 2012-08-03 2013-08-02 Compounds

Publications (2)

Publication Number Publication Date
CN104661994A CN104661994A (zh) 2015-05-27
CN104661994B true CN104661994B (zh) 2017-08-08

Family

ID=48948407

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380048873.3A Active CN104661994B (zh) 2012-08-03 2013-08-02 化合物

Country Status (18)

Country Link
US (1) US9249086B2 (enExample)
EP (1) EP2880012B1 (enExample)
JP (1) JP6280117B2 (enExample)
KR (1) KR102180174B1 (enExample)
CN (1) CN104661994B (enExample)
AU (1) AU2013298525B2 (enExample)
BR (1) BR112015002390B1 (enExample)
CA (1) CA2880422C (enExample)
CL (1) CL2015000233A1 (enExample)
ES (1) ES2908080T3 (enExample)
IL (1) IL236965B (enExample)
IN (1) IN2015DN00837A (enExample)
MX (1) MX364940B (enExample)
NZ (1) NZ629914A (enExample)
RU (1) RU2635563C2 (enExample)
SG (1) SG11201500805VA (enExample)
WO (1) WO2014020164A1 (enExample)
ZA (1) ZA201500778B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11235168B2 (en) 2015-12-17 2022-02-01 Photocure Asa Method of photodynamic therapy (PDT) for bladder cancer

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3082787B1 (en) * 2013-12-20 2020-11-25 Galderma Research & Development Pulse photodynamic treatment of photodamaged skin
US10457627B2 (en) * 2015-09-23 2019-10-29 Xw Laboratories Inc. Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof
GB201522309D0 (en) * 2015-12-17 2016-02-03 Photocure Asa Use
GB201522398D0 (en) 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy
CN106187793A (zh) * 2016-01-26 2016-12-07 赵鸣 5‑氨基酮戊酸及其衍生物的盐化合物和应用
PL3641882T3 (pl) * 2017-06-21 2024-02-26 Photocure Asa Sposób przygotowania ciekłej kompozycji farmaceutycznej oraz urządzenie do stosowania w takim sposobie
AU2020221841B2 (en) 2019-02-13 2025-10-09 Alpheus Medical, Inc. Non-invasive sonodynamic therapy
BR112021023836A8 (pt) 2019-05-29 2023-02-28 Sonalasense Inc Sonossensibilização
CA3185803A1 (en) 2020-08-07 2022-02-10 Vijay Agarwal Ultrasound arrays for enhanced sonodynamic therapy for treating cancer
KR20250154511A (ko) 2023-03-07 2025-10-28 포토큐어 에이에스에이 방광암 치료

Citations (2)

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CN1942430A (zh) * 2004-03-30 2007-04-04 克斯莫石油株式会社 5-氨基乙酰丙酸盐、其制备方法及其用途
CN101896203A (zh) * 2007-12-12 2010-11-24 光治疗Asa公司 固体形式的5-氨基酮戊酸和衍生物在光动力治疗和诊断中的应用

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JPH07188133A (ja) 1993-12-27 1995-07-25 Asahi Chem Ind Co Ltd δ−アミノレブリン酸またはその同族体の製造法
KR100444007B1 (ko) 1995-03-10 2004-12-03 포토큐레 에이에스에이 광화학치료또는진단에사용하기위한5-아미노레불린산의에스테르
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
JPH1112197A (ja) 1997-06-18 1999-01-19 Cosmo Sogo Kenkyusho:Kk 悪性腫瘍診断剤及び治療剤
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
DE10202487A1 (de) 2002-01-23 2003-07-31 Photonamic Gmbh & Co Kg Dermales Applikationssystem für Aminolävulinsäure-Derivate
DE10312659A1 (de) 2003-03-21 2004-10-07 Universität Regensburg 5-Aminolävulinsäurederivate und ihre Verwendung
GB0406917D0 (en) 2004-03-26 2004-04-28 Photocure Asa Compounds
JP4417865B2 (ja) 2004-03-30 2010-02-17 コスモ石油株式会社 5−アミノレブリン酸リン酸塩、その製造方法及びその用途
JP4719483B2 (ja) 2004-03-30 2011-07-06 コスモ石油株式会社 5−アミノレブリン酸スルホン酸塩の製造方法
GB0424833D0 (en) 2004-11-10 2004-12-15 Photocure Asa Method
JP5404995B2 (ja) 2006-08-10 2014-02-05 コスモ石油株式会社 植物のポリフェノール増量剤
JP5039389B2 (ja) 2007-02-02 2012-10-03 コスモ石油株式会社 ホップのアルファ酸又はホップオイル含量向上剤
ES2550243T3 (es) 2007-03-30 2015-11-05 Cosmo Ala Co., Ltd. Agente para mejorar la resistencia a los álcalis de una planta y método para mejorar la resistencia a los álcalis de una planta
JP4705616B2 (ja) 2007-07-20 2011-06-22 コスモ石油株式会社 植物における金属成分の吸収向上剤
EP2231105A1 (en) * 2007-12-14 2010-09-29 Photoderma SA Novel compounds useful in therapeutic and cosmetic methods
DK2272538T3 (da) 2008-04-22 2020-10-26 Sbi Pharmaceuticals Co Ltd Fremgangsmåde til påvisning af blærecancer
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JP5276894B2 (ja) 2008-05-13 2013-08-28 コスモ石油株式会社 イネの健苗育成向上剤
JP5323539B2 (ja) 2009-03-11 2013-10-23 コスモ石油株式会社 農作物の収穫部位の収量向上剤

Patent Citations (2)

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CN1942430A (zh) * 2004-03-30 2007-04-04 克斯莫石油株式会社 5-氨基乙酰丙酸盐、其制备方法及其用途
CN101896203A (zh) * 2007-12-12 2010-11-24 光治疗Asa公司 固体形式的5-氨基酮戊酸和衍生物在光动力治疗和诊断中的应用

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11235168B2 (en) 2015-12-17 2022-02-01 Photocure Asa Method of photodynamic therapy (PDT) for bladder cancer
US11980772B2 (en) 2015-12-17 2024-05-14 Photocure Asa Method of photodynamic therapy (PDT) for bladder cancer

Also Published As

Publication number Publication date
IN2015DN00837A (enExample) 2015-06-12
EP2880012A1 (en) 2015-06-10
HK1211283A1 (en) 2016-05-20
BR112015002390A8 (pt) 2019-07-30
CA2880422A1 (en) 2014-02-06
BR112015002390A2 (pt) 2017-07-04
KR102180174B1 (ko) 2020-11-19
SG11201500805VA (en) 2015-02-27
IL236965B (en) 2019-03-31
ZA201500778B (en) 2016-04-28
MX2015001374A (es) 2015-09-07
AU2013298525B2 (en) 2017-12-14
BR112015002390B1 (pt) 2020-03-24
RU2635563C2 (ru) 2017-11-14
US20150191419A1 (en) 2015-07-09
JP6280117B2 (ja) 2018-02-14
AU2013298525A1 (en) 2015-03-05
KR20150039208A (ko) 2015-04-09
ES2908080T3 (es) 2022-04-27
CA2880422C (en) 2021-02-09
CN104661994A (zh) 2015-05-27
MX364940B (es) 2019-05-15
US9249086B2 (en) 2016-02-02
RU2015104830A (ru) 2016-09-27
EP2880012B1 (en) 2021-12-15
WO2014020164A1 (en) 2014-02-06
JP2015528814A (ja) 2015-10-01
CL2015000233A1 (es) 2015-04-24
NZ629914A (en) 2017-02-24

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