JP2015518736A5 - - Google Patents
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- Publication number
- JP2015518736A5 JP2015518736A5 JP2015516270A JP2015516270A JP2015518736A5 JP 2015518736 A5 JP2015518736 A5 JP 2015518736A5 JP 2015516270 A JP2015516270 A JP 2015516270A JP 2015516270 A JP2015516270 A JP 2015516270A JP 2015518736 A5 JP2015518736 A5 JP 2015518736A5
- Authority
- JP
- Japan
- Prior art keywords
- bacterium
- nucleic acid
- acid encoding
- diol
- glycerol dehydratase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000894006 Bacteria Species 0.000 claims 17
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims 12
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 9
- 108010025885 Glycerol dehydratase Proteins 0.000 claims 9
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 9
- 102000039446 nucleic acids Human genes 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 108010065027 Propanediol Dehydratase Proteins 0.000 claims 8
- 150000002009 diols Chemical class 0.000 claims 8
- 230000035772 mutation Effects 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 230000007420 reactivation Effects 0.000 claims 5
- OWBTYPJTUOEWEK-QWWZWVQMSA-N (R,R)-butane-2,3-diol Chemical compound C[C@@H](O)[C@@H](C)O OWBTYPJTUOEWEK-QWWZWVQMSA-N 0.000 claims 4
- 101710088194 Dehydrogenase Proteins 0.000 claims 4
- 101710168863 Diacetyl reductase [(S)-acetoin forming] Proteins 0.000 claims 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 2
- 241001656809 Clostridium autoethanogenum Species 0.000 claims 2
- 108020004705 Codon Proteins 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 239000001963 growth medium Substances 0.000 claims 2
- 235000016709 nutrition Nutrition 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 1
- 241000588748 Klebsiella Species 0.000 claims 1
- 101000933577 Klebsiella pneumoniae Diacetyl reductase [(S)-acetoin forming] Proteins 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261657292P | 2012-06-08 | 2012-06-08 | |
| US61/657,292 | 2012-06-08 | ||
| PCT/US2013/044865 WO2013185123A1 (en) | 2012-06-08 | 2013-06-09 | Recombinant microorganisms and uses therefor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015518736A JP2015518736A (ja) | 2015-07-06 |
| JP2015518736A5 true JP2015518736A5 (enExample) | 2016-08-04 |
| JP6381525B2 JP6381525B2 (ja) | 2018-08-29 |
Family
ID=49712722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015516270A Active JP6381525B2 (ja) | 2012-06-08 | 2013-06-09 | 組換え微生物およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9890384B2 (enExample) |
| EP (1) | EP2859089B1 (enExample) |
| JP (1) | JP6381525B2 (enExample) |
| KR (1) | KR102079275B1 (enExample) |
| CN (2) | CN113186144A (enExample) |
| IN (1) | IN2014DN10508A (enExample) |
| WO (1) | WO2013185123A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130323820A1 (en) | 2012-06-01 | 2013-12-05 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| KR102121888B1 (ko) | 2012-08-28 | 2020-06-12 | 란자테크 뉴질랜드 리미티드 | 재조합 미생물 및 이에 대한 용도 |
| KR102324599B1 (ko) | 2013-09-22 | 2021-11-12 | 란자테크 뉴질랜드 리미티드 | 발효 공정 |
| KR101577502B1 (ko) * | 2013-12-16 | 2015-12-14 | 지에스칼텍스 주식회사 | Ｄ（－）２，３－부탄디올의 생성능이 증강된 재조합 미생물 및 이를 이용한 ｄ（－）２，３－부탄디올의 생산 방법 |
| ES2828707T3 (es) | 2014-01-28 | 2021-05-27 | Lanzatech New Zealand Ltd | Método para producir un microorganismo recombinante |
| KR101743021B1 (ko) | 2014-05-08 | 2017-06-02 | 한국생명공학연구원 | 재조합 미생물을 이용한 l형 2,3-부탄디올의 제조방법 |
| EP3210012B1 (en) | 2014-10-22 | 2023-06-07 | LanzaTech NZ, Inc. | Gas testing unit and method |
| TWI689592B (zh) | 2014-10-22 | 2020-04-01 | 紐西蘭商藍瑟科技紐西蘭有限公司 | 多段生物反應器方法 |
| EP3230459B1 (en) | 2014-12-08 | 2020-09-16 | LanzaTech New Zealand Limited | Recombinant microorganisms exhibiting increased flux through a fermentation pathway |
| EP3262153A4 (en) | 2015-02-23 | 2018-07-04 | Lanzatech New Zealand Limited | Recombinant acetogenic bacterium for the conversion of methane to products |
| KR20180056785A (ko) | 2015-10-13 | 2018-05-29 | 란자테크 뉴질랜드 리미티드 | 에너지-생성 발효 경로를 포함하는 유전자 조작된 박테리아 |
| CN108431208A (zh) | 2015-12-03 | 2018-08-21 | 朗泽科技新西兰有限公司 | 增补精氨酸以改善气体发酵产乙酸菌的效率 |
| US10358661B2 (en) | 2015-12-28 | 2019-07-23 | Lanzatech New Zealand Limited | Microorganism with modified hydrogenase activity |
| CN108603201A (zh) | 2016-02-01 | 2018-09-28 | 朗泽科技新西兰有限公司 | 整合发酵和电解工艺 |
| KR20180110144A (ko) | 2016-02-26 | 2018-10-08 | 란자테크 뉴질랜드 리미티드 | C1-고정 박테리아에 대한 crispr/cas 시스템 |
| WO2017200884A1 (en) | 2016-05-14 | 2017-11-23 | Lanzatech, Inc. | Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods |
| BR112020004591A2 (pt) | 2017-09-08 | 2020-09-08 | Lanzatech, Inc. | processo para produzir um ou mais produtos de fermentação |
| CN111936631A (zh) * | 2017-12-19 | 2020-11-13 | 朗泽科技有限公司 | 用于生物产生乙二醇的微生物和方法 |
| WO2019157507A1 (en) | 2018-02-12 | 2019-08-15 | Lanzatech, Inc. | A process for improving carbon conversion efficiency |
| KR102669528B1 (ko) | 2018-04-20 | 2024-05-29 | 란자테크, 인크. | 간헐적 전기분해 스트림 |
| US11097967B2 (en) | 2018-11-19 | 2021-08-24 | Lanzatech, Inc. | Integration of fermentation and gasification |
| CA3210756A1 (en) | 2019-01-29 | 2020-08-06 | Lanzatech, Inc. | Production of bio-based liquefied petroleum gas |
| MY203041A (en) | 2019-02-08 | 2024-06-05 | Lanzatech Inc | Process for recovering close boiling products |
| WO2020188033A1 (en) | 2019-03-20 | 2020-09-24 | Global Bioenergies | Improved means and methods for producing isobutene from acetyl-coa |
| US11772038B2 (en) | 2019-07-11 | 2023-10-03 | Lanzatech, Inc. | Methods for optimizing gas utilization |
| US11932818B2 (en) | 2020-03-16 | 2024-03-19 | Lanzatech, Inc. | Tail gas of gas fermentation to dry gasification feedstock |
| CN113840909A (zh) | 2020-03-18 | 2021-12-24 | 朗泽科技有限公司 | 从气态底物发酵生产2-苯乙醇 |
| CA3177077A1 (en) | 2020-04-29 | 2021-11-04 | Lanzatech, Inc. | Fermentative production of ?-ketoadipate from gaseous substrates |
| MY197253A (en) | 2020-06-06 | 2023-06-08 | Lanzatech Inc | Microorganism with knock-in at acetolactate decarboxylase gene locus |
| KR102725416B1 (ko) | 2021-02-08 | 2024-11-04 | 란자테크, 인크. | 재조합 미생물 및 이의 용도 |
| BR112023020761A2 (pt) | 2021-04-09 | 2023-12-12 | Lanzatech Inc | Processo para fornecer uma matéria-prima, e, aparelho para fornecer uma matéria-prima de fermentação gasosa |
| WO2023004293A1 (en) | 2021-07-20 | 2023-01-26 | Lanzatech, Inc. | Recombinant microorganisms and uses therefor |
| TW202307202A (zh) | 2021-08-06 | 2023-02-16 | 美商朗澤科技有限公司 | 用於改良乙二醇之生物產生的微生物及方法 |
| US12091648B2 (en) | 2021-11-03 | 2024-09-17 | Lanzatech, Inc. | System and method for generating bubbles in a vessel |
| US12280331B2 (en) | 2022-04-29 | 2025-04-22 | Lanzatech, Inc. | Low residence time gas separator |
| US12077800B2 (en) | 2022-06-16 | 2024-09-03 | Lanzatech, Inc. | Liquid distributor system and process of liquid distribution |
| CN119403929A (zh) | 2022-06-21 | 2025-02-07 | 朗泽科技有限公司 | 用于由c1底物连续共产生高价值专用蛋白和化学产物的微生物和方法 |
| WO2023250382A1 (en) | 2022-06-21 | 2023-12-28 | Lanzatech, Inc. | Microorganisms and methods for the continuous co-production of tandem repeat proteins and chemical products from c1-substrates |
| WO2024036187A1 (en) | 2022-08-10 | 2024-02-15 | Lanzatech, Inc. | Carbon sequestration in soils with production of chemical products |
| KR20240024407A (ko) * | 2022-08-16 | 2024-02-26 | 한국과학기술원 | 일산화탄소 이용능이 증대된 미생물 및 이를 이용한 2,3-bdo 생산 |
| US12359224B2 (en) | 2023-06-05 | 2025-07-15 | Lanzatech, Inc. | Integrated gas fermentation and carbon black processes |
| WO2024253882A1 (en) | 2023-06-05 | 2024-12-12 | Lanzatech, Inc. | Integrated gas fermentation |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
| US5593886A (en) | 1992-10-30 | 1997-01-14 | Gaddy; James L. | Clostridium stain which produces acetic acid from waste gases |
| UA72220C2 (uk) | 1998-09-08 | 2005-02-15 | Байоенджініерінг Рісорсиз, Інк. | Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання |
| DE60121335T2 (de) | 2000-07-25 | 2007-08-02 | Emmaus Foundation, Inc., Fayetteville | Verfahren zur steigerung der ethanolproduktion bei der mikrobiellen fermentation |
| CN101437948A (zh) * | 2006-05-02 | 2009-05-20 | 纳幕尔杜邦公司 | 四碳醇的发酵生产 |
| US8206970B2 (en) * | 2006-05-02 | 2012-06-26 | Butamax(Tm) Advanced Biofuels Llc | Production of 2-butanol and 2-butanone employing aminobutanol phosphate phospholyase |
| US7704723B2 (en) | 2006-08-31 | 2010-04-27 | The Board Of Regents For Oklahoma State University | Isolation and characterization of novel clostridial species |
| US20080274522A1 (en) * | 2007-05-02 | 2008-11-06 | Bramucci Michael G | Method for the production of 2-butanone |
| FR2916000B1 (fr) * | 2007-05-07 | 2013-07-05 | Lallemand Sas | Moyens pour reduire l'accumulation d'acetoine dans des milieux de fermentation alcoolique |
| CA2703622C (en) | 2007-11-13 | 2014-12-16 | Lanzatech New Zealand Limited | Clostridium autoethanogenum strain and methods of use thereof to produce ethanol and acetate |
| US8372612B2 (en) * | 2007-12-21 | 2013-02-12 | Butamax(Tm) Advanced Biofuels Llc | Production of four carbon alcohols using improved strain |
| NZ589632A (en) | 2008-06-09 | 2013-03-28 | Lanzatech New Zealand Ltd | Production of butanediol by anaerobic microbial fermentation |
| BRPI0913547A2 (pt) * | 2008-09-29 | 2020-08-18 | Butamax Advanced Biofuels Llc | célula bacteriana ácido-lática recombinante, método para a produção de 2-butanol e método para a produção de 2-butanona |
| US20100184173A1 (en) * | 2008-11-14 | 2010-07-22 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
| US8039239B2 (en) * | 2008-12-16 | 2011-10-18 | Coskata, Inc. | Recombinant microorganisms having modified production of alcohols and acids |
| JP2012511928A (ja) * | 2008-12-16 | 2012-05-31 | ゲノマチカ， インク． | 合成ガス及び他の炭素源の有用な製品への変換のための微生物及び方法 |
| WO2011041426A1 (en) * | 2009-09-29 | 2011-04-07 | Butamax(Tm) Advanced Biofuels Llc | Improved yeast production host cells |
| US8143037B2 (en) | 2010-03-19 | 2012-03-27 | Coskata, Inc. | Ethanologenic Clostridium species, Clostridium coskatii |
| US8759070B2 (en) * | 2010-09-10 | 2014-06-24 | University Of Delaware | Recombinant clostridia that fix CO2 and CO and uses thereof |
| US20110236941A1 (en) * | 2010-10-22 | 2011-09-29 | Lanzatech New Zealand Limited | Recombinant microorganism and methods of production thereof |
| PL2678432T4 (pl) | 2011-02-25 | 2019-05-31 | Lanzatech New Zealand Ltd | Rekombinowane mikroorganizmy i ich zastosowania |
| WO2014092562A1 (en) * | 2012-12-11 | 2014-06-19 | Photanol B.V. | Synthesis of acetoin, 2,3-butanediol and 2-butanol by cyanobacteria by heterologous expression of a catabolic pathway |
-
2013
- 2013-06-09 CN CN202110477268.4A patent/CN113186144A/zh active Pending
- 2013-06-09 JP JP2015516270A patent/JP6381525B2/ja active Active
- 2013-06-09 KR KR1020147036648A patent/KR102079275B1/ko active Active
- 2013-06-09 WO PCT/US2013/044865 patent/WO2013185123A1/en not_active Ceased
- 2013-06-09 EP EP13800454.4A patent/EP2859089B1/en active Active
- 2013-06-09 CN CN201380042293.3A patent/CN104919037A/zh active Pending
- 2013-06-10 US US13/914,234 patent/US9890384B2/en active Active
-
2014
- 2014-12-09 IN IN10508DEN2014 patent/IN2014DN10508A/en unknown
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