JP2015518473A5 - - Google Patents

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JP2015518473A5
JP2015518473A5 JP2015503659A JP2015503659A JP2015518473A5 JP 2015518473 A5 JP2015518473 A5 JP 2015518473A5 JP 2015503659 A JP2015503659 A JP 2015503659A JP 2015503659 A JP2015503659 A JP 2015503659A JP 2015518473 A5 JP2015518473 A5 JP 2015518473A5
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JP2015518473A (ja
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Priority claimed from PCT/US2013/034672 external-priority patent/WO2013149185A1/en
Publication of JP2015518473A publication Critical patent/JP2015518473A/ja
Publication of JP2015518473A5 publication Critical patent/JP2015518473A5/ja
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JP2015503659A 2012-03-29 2013-03-29 ツブリシン誘導体およびその複合体の製造方法 Pending JP2015518473A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261617386P 2012-03-29 2012-03-29
US61/617,386 2012-03-29
US201261684450P 2012-08-17 2012-08-17
US61/684,450 2012-08-17
US201361771451P 2013-03-01 2013-03-01
US61/771,451 2013-03-01
US201361794720P 2013-03-15 2013-03-15
US61/794,720 2013-03-15
PCT/US2013/034672 WO2013149185A1 (en) 2012-03-29 2013-03-29 Processes for preparing tubulysin derivatives and conjugates thereof

Publications (2)

Publication Number Publication Date
JP2015518473A JP2015518473A (ja) 2015-07-02
JP2015518473A5 true JP2015518473A5 (https=) 2016-05-19

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JP2015503659A Pending JP2015518473A (ja) 2012-03-29 2013-03-29 ツブリシン誘導体およびその複合体の製造方法

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US (2) US20140080175A1 (https=)
EP (1) EP2831059B1 (https=)
JP (1) JP2015518473A (https=)
CA (1) CA2868494A1 (https=)
WO (1) WO2013149185A1 (https=)

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US20140080175A1 (en) 2012-03-29 2014-03-20 Endocyte, Inc. Processes for preparing tubulysin derivatives and conjugates thereof
EP2908818A4 (en) 2012-10-16 2016-07-13 Endocyte Inc CONJUGATES OF DRUG DELIVERY CONTAINING ARTIFICIAL AMINO ACIDS AND METHODS OF USE
BR112015011118B1 (pt) 2012-11-15 2022-12-13 Endocyte, Inc Conjugado; composição farmacêutica; e uso de um conjugado
US20140249315A1 (en) * 2013-03-01 2014-09-04 Endocyte, Inc. Processes for preparing tubulysins
WO2015113760A1 (en) * 2014-01-28 2015-08-06 Tube Pharmaceuticals Gmbh Cytotoxic tubulysin compounds for conjugation
EP3131587A4 (en) * 2014-04-14 2017-11-01 Endocyte, Inc. Drug delivery conjugates for treating resistant cancer and for use in combination therapy
US20160074527A1 (en) * 2014-09-17 2016-03-17 Genentech, Inc. Pyrrolobenzodiazepines and antibody disulfide conjugates thereof
HK1248069A1 (zh) * 2015-02-25 2018-10-12 William Marsh Rice University 去乙酰氧基微管溶素h及其类似物
WO2017031209A1 (en) * 2015-08-18 2017-02-23 Endocyte, Inc. Tubulysin analogs and methods
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MA53765B2 (fr) * 2018-12-21 2025-04-30 Regeneron Pharmaceuticals, Inc. Tubulysines et conjugués tubulysines-protéines

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