JP2015514728A5 - - Google Patents
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- Publication number
- JP2015514728A5 JP2015514728A5 JP2015506121A JP2015506121A JP2015514728A5 JP 2015514728 A5 JP2015514728 A5 JP 2015514728A5 JP 2015506121 A JP2015506121 A JP 2015506121A JP 2015506121 A JP2015506121 A JP 2015506121A JP 2015514728 A5 JP2015514728 A5 JP 2015514728A5
- Authority
- JP
- Japan
- Prior art keywords
- residue
- aliphatic residue
- aliphatic
- polysubstituted
- unsubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 Cc1c(C(NCC(*)(*)C(*)(*)O)=O)c(*)nc(N2CCOCC2)c1 Chemical compound Cc1c(C(NCC(*)(*)C(*)(*)O)=O)c(*)nc(N2CCOCC2)c1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12002709 | 2012-04-18 | ||
| EP12002709.9 | 2012-04-18 | ||
| PCT/EP2013/001134 WO2013156154A1 (en) | 2012-04-18 | 2013-04-17 | Substituted 6-amino-nicotinamides bearing an oh-containing group as kcnq2/3 modulators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015514728A JP2015514728A (ja) | 2015-05-21 |
| JP2015514728A5 true JP2015514728A5 (https=) | 2016-06-02 |
| JP6033403B2 JP6033403B2 (ja) | 2016-11-30 |
Family
ID=48227140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015506121A Expired - Fee Related JP6033403B2 (ja) | 2012-04-18 | 2013-04-17 | Ｋｃｎｑ２／３調節因子としてのｏｈ含有基を有する置換６−アミノ−ニコチンアミド類 |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP2888233B1 (https=) |
| JP (1) | JP6033403B2 (https=) |
| CN (1) | CN104428287A (https=) |
| AR (1) | AR090739A1 (https=) |
| AU (1) | AU2013248637A1 (https=) |
| BR (1) | BR112014025840A2 (https=) |
| CA (1) | CA2870573A1 (https=) |
| CY (1) | CY1118255T1 (https=) |
| DK (1) | DK2888233T3 (https=) |
| EA (1) | EA201401142A1 (https=) |
| ES (1) | ES2605947T3 (https=) |
| HK (1) | HK1210173A1 (https=) |
| HR (1) | HRP20161424T1 (https=) |
| HU (1) | HUE030859T2 (https=) |
| IL (1) | IL235030A0 (https=) |
| LT (1) | LT2888233T (https=) |
| MX (1) | MX2014012494A (https=) |
| PT (1) | PT2888233T (https=) |
| RS (1) | RS55466B1 (https=) |
| SI (1) | SI2888233T1 (https=) |
| WO (1) | WO2013156154A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201809184VA (en) * | 2016-04-22 | 2018-11-29 | Ono Pharmaceutical Co | Crystal polymorphism of kcnq2-5 channel activator |
| JP7262468B2 (ja) * | 2017-12-29 | 2023-04-21 | スリーエム イノベイティブ プロパティズ カンパニー | 熱硬化性２剤型加工用接着剤組成物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2230392A1 (de) | 1972-06-22 | 1974-01-31 | Cassella Farbwerke Mainkur Ag | Substituierte pyridinverbindungen und verfahren zu ihrer herstellung |
| DE2513949A1 (de) | 1975-03-29 | 1976-10-07 | Bayer Ag | Azofarbstoffe |
| CA2438868A1 (en) | 2001-02-20 | 2002-09-19 | Valentin K. Gribkoff | Modulators of kcnq potassium channels and use thereof in treating migraine and mechanistically related diseases |
| US20020183335A1 (en) * | 2001-02-20 | 2002-12-05 | Piyasena Hewawasam | 2, 4-disubstituted pyrimidine-5-carboxamide derivatives as KCNQ potassium channel modulators |
| EP2086935A1 (de) * | 2006-10-16 | 2009-08-12 | Grünenthal GmbH | Substituierte sulfonamid-derivate als bradykinin 1 rezeptor modulatoren |
| DE102006049452A1 (de) | 2006-10-17 | 2008-05-08 | Grünenthal GmbH | Substituierte Tetrahydropyrolopiperazin-Verbindungen und deren Verwendung in Arzneimitteln |
| HRP20120822T1 (hr) | 2008-10-24 | 2012-11-30 | Grünenthal GmbH | Supstituirani 4,5,6,7-tetrahidrotienopiridini kao kcnq2/3 modulatori za lijeäśenje boli, epilepsije i urinarne inkontinencije |
| TWI475020B (zh) | 2009-03-12 | 2015-03-01 | The substituted nicotine amide as a KCNQ2 / 3 modifier | |
| PE20140199A1 (es) * | 2010-10-20 | 2014-02-16 | Gruenenthal Chemie | 6-amino-nicotinamidas sustituidas como moduladores de kcnq2/3 |
-
2013
- 2013-04-17 ES ES13719386.8T patent/ES2605947T3/es active Active
- 2013-04-17 DK DK13719386.8T patent/DK2888233T3/en active
- 2013-04-17 LT LTEP13719386.8T patent/LT2888233T/lt unknown
- 2013-04-17 HR HRP20161424TT patent/HRP20161424T1/hr unknown
- 2013-04-17 WO PCT/EP2013/001134 patent/WO2013156154A1/en not_active Ceased
- 2013-04-17 EP EP13719386.8A patent/EP2888233B1/en not_active Not-in-force
- 2013-04-17 MX MX2014012494A patent/MX2014012494A/es unknown
- 2013-04-17 HU HUE13719386A patent/HUE030859T2/en unknown
- 2013-04-17 EA EA201401142A patent/EA201401142A1/ru unknown
- 2013-04-17 SI SI201330394A patent/SI2888233T1/sl unknown
- 2013-04-17 AU AU2013248637A patent/AU2013248637A1/en not_active Abandoned
- 2013-04-17 HK HK15111080.1A patent/HK1210173A1/xx unknown
- 2013-04-17 RS RS20161120A patent/RS55466B1/sr unknown
- 2013-04-17 CN CN201380019282.3A patent/CN104428287A/zh active Pending
- 2013-04-17 CA CA2870573A patent/CA2870573A1/en not_active Abandoned
- 2013-04-17 BR BR112014025840A patent/BR112014025840A2/pt not_active IP Right Cessation
- 2013-04-17 JP JP2015506121A patent/JP6033403B2/ja not_active Expired - Fee Related
- 2013-04-17 PT PT137193868T patent/PT2888233T/pt unknown
- 2013-04-18 AR ARP130101283A patent/AR090739A1/es unknown
-
2014
- 2014-10-07 IL IL235030A patent/IL235030A0/en unknown
-
2016
- 2016-11-24 CY CY20161101222T patent/CY1118255T1/el unknown
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