JP2015512450A5 - - Google Patents
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- Publication number
- JP2015512450A5 JP2015512450A5 JP2015504701A JP2015504701A JP2015512450A5 JP 2015512450 A5 JP2015512450 A5 JP 2015512450A5 JP 2015504701 A JP2015504701 A JP 2015504701A JP 2015504701 A JP2015504701 A JP 2015504701A JP 2015512450 A5 JP2015512450 A5 JP 2015512450A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- hyo
- antigen
- pcv2
- soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102000036639 antigens Human genes 0.000 claims description 36
- 108091007433 antigens Proteins 0.000 claims description 36
- 239000000427 antigen Substances 0.000 claims description 31
- 241001673669 Porcine circovirus 2 Species 0.000 claims description 24
- 241000700605 Viruses Species 0.000 claims description 24
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 claims description 22
- 239000002671 adjuvant Substances 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 11
- 230000002163 immunogen Effects 0.000 claims description 9
- 108060003951 Immunoglobulin Proteins 0.000 claims description 7
- 102000018358 immunoglobulin Human genes 0.000 claims description 7
- 101710167800 Capsid assembly scaffolding protein Proteins 0.000 claims description 6
- 101710113540 ORF2 protein Proteins 0.000 claims description 6
- 101710090523 Putative movement protein Proteins 0.000 claims description 6
- 230000001413 cellular effect Effects 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 241000204045 Mycoplasma hyopneumoniae Species 0.000 claims description 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 230000028993 immune response Effects 0.000 claims description 3
- 230000001681 protective effect Effects 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 241001533384 Circovirus Species 0.000 claims description 2
- 241000928435 Porcine circovirus 1 Species 0.000 claims description 2
- 101710120037 Toxin CcdB Proteins 0.000 claims description 2
- 229930003427 Vitamin E Natural products 0.000 claims description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 2
- 230000003053 immunization Effects 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- 241000701447 unidentified baculovirus Species 0.000 claims description 2
- 229940046009 vitamin E Drugs 0.000 claims description 2
- 235000019165 vitamin E Nutrition 0.000 claims description 2
- 239000011709 vitamin E Substances 0.000 claims description 2
- 229960005486 vaccine Drugs 0.000 claims 4
- 241000282887 Suidae Species 0.000 claims 3
- 241000282898 Sus scrofa Species 0.000 claims 3
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 206010035664 Pneumonia Diseases 0.000 claims 1
- 241000202347 Porcine circovirus Species 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 244000144972 livestock Species 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000000241 respiratory effect Effects 0.000 claims 1
- 101710098119 Chaperonin GroEL 2 Proteins 0.000 description 1
- 241000202934 Mycoplasma pneumoniae Species 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261620189P | 2012-04-04 | 2012-04-04 | |
| US61/620,189 | 2012-04-04 | ||
| PCT/US2013/035091 WO2013152086A1 (en) | 2012-04-04 | 2013-04-03 | Pcv/mycoplasma hyopneumoniae/prrs combination vaccine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015512450A JP2015512450A (ja) | 2015-04-27 |
| JP2015512450A5 true JP2015512450A5 (cg-RX-API-DMAC10.html) | 2016-06-02 |
| JP6271504B2 JP6271504B2 (ja) | 2018-01-31 |
Family
ID=48140160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015504701A Active JP6271504B2 (ja) | 2012-04-04 | 2013-04-03 | Ｐｃｖ／マイコプラズマ・ハイオニューモニエ／ｐｒｒｓ混合ワクチン |
Country Status (32)
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005515162A (ja) | 2001-07-02 | 2005-05-26 | ファイザー・プロダクツ・インク | マイコプラズマ・ハイオニューモニエ（Ｍｙｃｏｐｌａｓｍａｈｙｏｐｎｅｕｍｏｎｉａｅ）を用いた単回ワクチン接種 |
| US8546149B2 (en) | 2010-08-27 | 2013-10-01 | Intervet Inc. | Potency test for vaccine formulations |
| UA114503C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
| UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| US9120859B2 (en) * | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
| PT2938747T (pt) | 2012-12-28 | 2019-08-01 | Boehringer Ingelheim Vetmedica Gmbh | Método de preparação de uma vacina de micoplasma |
| AU2013370982C9 (en) | 2012-12-28 | 2019-01-24 | Boehringer Ingelheim Vetmedica Gmbh | Immunogenic composition comprising mycoplasma antigens |
| EP2994162B1 (en) | 2013-05-08 | 2021-04-07 | Pharmgate Biologics Inc. | Vaccine for pcv2 and mycoplasma |
| DK3072523T3 (en) * | 2013-11-21 | 2019-04-08 | Agricultural Tech Res Inst | COMPOSITION FOR PREVENTION AND TREATMENT OF INFECTIONS WITH MYCOPLASMA |
| KR102360690B1 (ko) * | 2013-12-03 | 2022-02-08 | 인터벳 인터내셔널 비.브이. | Ｐｒｒｓ 및 로소니아 인트라셀룰라리스에 대한 돼지 백신 |
| PL3076996T3 (pl) * | 2013-12-03 | 2020-05-18 | Intervet International B.V. | Szczepionka przeciwko cirkowirusowi świń typu 2 |
| CN104056265B (zh) * | 2014-07-11 | 2016-04-27 | 江苏南农高科技股份有限公司 | 猪圆环病毒2型、猪繁殖与呼吸综合征二联疫苗及其制备方法 |
| CN107073103A (zh) * | 2014-09-12 | 2017-08-18 | 英特维特国际股份有限公司 | 用于保护猪免于猪流行性腹泻病毒的疫苗 |
| CN107073102B (zh) * | 2014-09-12 | 2021-06-25 | 英特维特国际股份有限公司 | 用于保护母猪的后代免于猪流行性腹泻病毒的疫苗 |
| EP3229832A1 (en) * | 2014-12-11 | 2017-10-18 | Intervet International B.V. | Process for ready-to-use pcv2/m.hyo combination vaccine |
| AU2016380864B2 (en) | 2015-12-28 | 2019-10-31 | Boehringer Ingelheim Animal Health USA Inc. | M hyo multivalent vaccine and uses thereof |
| BR112018069100A2 (pt) * | 2016-03-23 | 2019-01-29 | Intervet International B.V. | uma vacina combinada contra a infecção por vírus pcv2 e mycoplasma hyopneumoniae |
| BR112018069219A2 (pt) | 2016-03-23 | 2019-01-22 | Intervet Int Bv | uma vacina para aplicação intradérmica contra infecção pelo vírus pcv2 e prrs |
| CN109476711B (zh) * | 2016-08-09 | 2023-08-08 | 财团法人农业科技研究院 | 防治猪鼻霉浆菌感染的组合物及生产该组合物的方法 |
| UA124976C2 (uk) * | 2016-12-14 | 2021-12-22 | Зоетіс Сервісіз Ллс | Вакцина для захисту тварини свині від зараження вірусом prrs |
| CA3045563C (en) * | 2016-12-23 | 2022-05-03 | Intervet International B.V. | Combination vaccine for swine |
| CA3058281A1 (en) * | 2017-04-13 | 2018-10-18 | Intervet International B.V. | Vaccines containing swine pathogens for associated non-mixed use |
| CN109280642B (zh) * | 2017-07-21 | 2022-07-22 | 浙江海隆生物科技有限公司 | CHO细胞株及其制备方法和使用该CHO细胞株制备猪圆环病毒2型Cap蛋白及其应用 |
| JP7354106B2 (ja) | 2017-12-04 | 2023-10-02 | インターベット インターナショナル ベー． フェー． | レプリコン粒子および油性アジュバントによるワクチン接種 |
| CA3085535A1 (en) * | 2017-12-22 | 2019-06-27 | Hipra Scientific, S.L.U. | Intradermal combination vaccine against mycoplasma and porcine circovirus |
| CN119488586A (zh) | 2018-03-26 | 2025-02-21 | 勃林格殷格翰动物保健美国有限公司 | 制备免疫原性组合物的方法 |
| KR102769557B1 (ko) * | 2021-11-19 | 2025-02-20 | 주식회사 이노백 | 신규한 재조합 돼지 써코바이러스 2형 단백질 및 이의 용도 |
| CN115851616A (zh) * | 2022-09-23 | 2023-03-28 | 江西正邦科技股份有限公司 | 猪伪狂犬病毒毒株、猪圆环病毒2型毒株、四联灭活疫苗及其制备方法 |
| CN119913202B (zh) * | 2025-01-15 | 2025-09-19 | 北京华夏兴洋生物科技有限公司 | 用于制备猪三联疫苗的重组载体、重组病毒及其应用 |
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| TWI449533B (zh) * | 2008-04-18 | 2014-08-21 | Intervet Int Bv | 防備胞內勞森菌（Ｌａｗｓｏｎｉａ ｉｎｔｒａｃｅｌｌｕｌａｒｉｓ）、豬肺炎黴漿菌（Ｍｙｃｏｐｌａｓｍａ ｈｙｏｐｎｅｕｍｏｎｉａｅ）及豬環狀病毒（Ｐｏｒｃｉｎｅ ｃｉｒｃｏ ｖｉｒｕｓ）用疫苗 |
| KR101320192B1 (ko) | 2008-10-16 | 2013-10-30 | 조에티스 엘엘씨 | 토크 테노 바이러스(ｔｔｖ) 분리물 및 조성물 |
| ES2559445T3 (es) | 2010-05-11 | 2016-02-12 | Intervet International B.V. | Vacuna contra Mycoplasma hyopneumoniae apta para la administración en presencia de anticuerpos de origen materno |
| US8546149B2 (en) | 2010-08-27 | 2013-10-01 | Intervet Inc. | Potency test for vaccine formulations |
| EP2609428B1 (en) * | 2010-08-27 | 2016-02-10 | Intervet International B.V. | Potency test for vaccine formulations |
| UA108902C2 (uk) | 2010-11-10 | 2015-06-25 | Вірус північноамериканського репродуктивного та респіраторного синдрому свиней (prrs) та його застосування | |
| MX362166B (es) | 2012-03-07 | 2018-12-14 | Ceva Sante Animale | Nueva vacuna veterinaria. |
| UA114504C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
| US9120859B2 (en) * | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
| UA114503C2 (uk) * | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
-
2013
- 2013-03-04 UA UAA201410839A patent/UA114504C2/uk unknown
- 2013-03-26 US US13/850,331 patent/US9125886B2/en active Active
- 2013-04-02 TW TW102111963A patent/TWI504406B/zh active
- 2013-04-03 HR HRP20140956AA patent/HRP20140956A2/hr not_active Application Discontinuation
- 2013-04-03 MY MYPI2014702759A patent/MY168549A/en unknown
- 2013-04-03 LT LTEP13717118.7T patent/LT2833909T/lt unknown
- 2013-04-03 ES ES13717118T patent/ES2719483T3/es active Active
- 2013-04-03 SI SI201331404T patent/SI2833909T1/sl unknown
- 2013-04-03 TR TR2019/05176T patent/TR201905176T4/tr unknown
- 2013-04-03 KR KR1020147030871A patent/KR101808903B1/ko active Active
- 2013-04-03 RU RU2014140108A patent/RU2644256C2/ru active
- 2013-04-03 EP EP13717118.7A patent/EP2833909B1/en not_active Revoked
- 2013-04-03 AU AU2013243540A patent/AU2013243540C1/en not_active Ceased
- 2013-04-03 PL PL13717118T patent/PL2833909T3/pl unknown
- 2013-04-03 MX MX2014012016A patent/MX336502B/es unknown
- 2013-04-03 CA CA2869601A patent/CA2869601C/en active Active
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- 2013-04-03 MX MX2015015469A patent/MX354773B/es unknown
- 2013-04-03 DK DK13717118.7T patent/DK2833909T3/en active
- 2013-04-03 RS RS20190354A patent/RS58480B1/sr unknown
- 2013-04-03 WO PCT/US2013/035091 patent/WO2013152086A1/en not_active Ceased
- 2013-04-03 EP EP19155397.3A patent/EP3508217A1/en active Pending
- 2013-04-03 BR BR112014024775-7A patent/BR112014024775B1/pt active IP Right Grant
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- 2013-04-03 JP JP2015504701A patent/JP6271504B2/ja active Active
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- 2013-04-04 AR ARP130101115 patent/AR090614A1/es not_active Application Discontinuation
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2014
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2015
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2019
- 2019-04-12 CY CY20191100407T patent/CY1121578T1/el unknown
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