ES2097840T3 - Adyuvante de vacuna que comprende un tetrapoliol. - Google Patents
Adyuvante de vacuna que comprende un tetrapoliol.Info
- Publication number
- ES2097840T3 ES2097840T3 ES92113037T ES92113037T ES2097840T3 ES 2097840 T3 ES2097840 T3 ES 2097840T3 ES 92113037 T ES92113037 T ES 92113037T ES 92113037 T ES92113037 T ES 92113037T ES 2097840 T3 ES2097840 T3 ES 2097840T3
- Authority
- ES
- Spain
- Prior art keywords
- emulsion
- amount
- tetrapoliol
- vaccine adjuvant
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Abstract
SE MUESTRA UN ADJUTOR PARA POTENCIAR LA INMUNOGENICIDAD DE UN ANTIGENO, QUE SE PUEDE FABRICAR A ESCALA COMERCIAL, Y QUE ES UNA EMULSION CON PARTICULAS ACEITOSAS DISPERSADAS EN UNA FASE ACUOSA CONTINUA; DICHA EMULSION COMPRENDE: UNA CANTIDAD FORMANTE DE EMULSION DE UN TRETA E, UN CANTIDAD FORMANTE DE EMULSION DE UN ACEITE METABOLIZABLE NO TOXICO; OPCIONALMENTE UNA CANTIDAD ESTABILIZANTE DE EMULSION DE UNA SUPERFICIATIVO BASADO EN ETER GLICOL; Y UNA CANTIDAD INMUNOPOTENCIADORA DE UN GLICOPEPTIDO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11642587A | 1987-11-03 | 1987-11-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2097840T3 true ES2097840T3 (es) | 1997-04-16 |
Family
ID=22367122
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92113037T Expired - Lifetime ES2097840T3 (es) | 1987-11-03 | 1988-11-02 | Adyuvante de vacuna que comprende un tetrapoliol. |
ES88118263T Expired - Lifetime ES2052674T3 (es) | 1987-11-03 | 1988-11-02 | Adyuvante de vacunas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88118263T Expired - Lifetime ES2052674T3 (es) | 1987-11-03 | 1988-11-02 | Adyuvante de vacunas. |
Country Status (11)
Country | Link |
---|---|
EP (2) | EP0315153B1 (es) |
JP (2) | JP2746272B2 (es) |
AT (1) | ATE149091T1 (es) |
AU (1) | AU626271B2 (es) |
CA (1) | CA1338618C (es) |
DE (2) | DE3889521T2 (es) |
ES (2) | ES2097840T3 (es) |
HU (1) | HU210825A9 (es) |
IE (1) | IE63692B1 (es) |
NZ (1) | NZ226811A (es) |
ZA (1) | ZA888209B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0832638B2 (ja) | 1989-05-25 | 1996-03-29 | カイロン コーポレイション | サブミクロン油滴乳剤を含んで成るアジュバント製剤 |
US5709860A (en) * | 1991-07-25 | 1998-01-20 | Idec Pharmaceuticals Corporation | Induction of cytotoxic T-lymphocyte responses |
ES2053402B1 (es) * | 1993-01-15 | 1995-02-01 | Hipra Lab Sa | Metodo de preparacion de vacunas inactivadas y vacunas vivas adyuvantadas asi como las vacunas obtenidas por dicho metodo. |
DE4333376C2 (de) * | 1993-09-30 | 1995-09-07 | Gerbu Biotechnik Gmbh | Mittel zur Steigerung der Ausbeute von Antikörpern in der Immunologie |
GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
ES2242604T3 (es) | 1999-02-26 | 2005-11-16 | Chiron Corporation | Microemulsiones con macroparticulas y microparticulas adsorbidas. |
US7854934B2 (en) | 1999-08-20 | 2010-12-21 | Sloan-Kettering Institute For Cancer Research | Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof |
AU6921300A (en) | 1999-08-20 | 2001-03-19 | Sloan-Kettering Institute For Cancer Research | Novel glycoconjugates, glycoamino, acids, intermediates thereto, and uses thereof |
US7824687B2 (en) | 1999-08-20 | 2010-11-02 | Sloan-Kettering Institute For Cancer Research | Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof |
AU770475B2 (en) * | 1999-12-23 | 2004-02-19 | Aphton Corporation | A stable immunogenic composition for frozen storage |
FR2804026B1 (fr) * | 2000-01-21 | 2004-06-11 | Merial Sas | Vaccination contre l'herpesvirose canine et vaccins |
US7018638B2 (en) | 2000-12-19 | 2006-03-28 | Wyeth | Mycoplasma hyopneumoniae bacterin vaccine |
MY129765A (en) * | 2000-12-19 | 2007-04-30 | Wyeth Corp | Improved mycoplasma hyopneumoniae bacterin vaccine |
RU2541809C2 (ru) | 2003-04-04 | 2015-02-20 | Зоетис Пи ЛЛК | Микрофлюидизированные эмульсии "масло в воде" и композиции вакцины |
AU2011265184B2 (en) | 2010-06-11 | 2016-08-04 | Sloan-Kettering Institute For Cancer Research | Multivalent glycopeptide constructs and uses thereof |
UA114504C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs |
UA114503C2 (uk) | 2012-04-04 | 2017-06-26 | Зоетіс Сервісіз Ллс | Комбінована вакцина pcv та mycoplasma hyopneumoniae |
US9120859B2 (en) | 2012-04-04 | 2015-09-01 | Zoetis Services Llc | Mycoplasma hyopneumoniae vaccine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
DE3750176T2 (de) * | 1986-09-22 | 1994-10-13 | Univ Emory | Impfstoff und verfahren zur herstellung. |
-
1988
- 1988-11-02 AU AU24588/88A patent/AU626271B2/en not_active Ceased
- 1988-11-02 ES ES92113037T patent/ES2097840T3/es not_active Expired - Lifetime
- 1988-11-02 JP JP63278546A patent/JP2746272B2/ja not_active Expired - Fee Related
- 1988-11-02 NZ NZ226811A patent/NZ226811A/en unknown
- 1988-11-02 DE DE3889521T patent/DE3889521T2/de not_active Expired - Fee Related
- 1988-11-02 DE DE3855807T patent/DE3855807T2/de not_active Expired - Fee Related
- 1988-11-02 IE IE330588A patent/IE63692B1/en not_active IP Right Cessation
- 1988-11-02 ES ES88118263T patent/ES2052674T3/es not_active Expired - Lifetime
- 1988-11-02 EP EP88118263A patent/EP0315153B1/en not_active Expired - Lifetime
- 1988-11-02 ZA ZA888209A patent/ZA888209B/xx unknown
- 1988-11-02 CA CA000582048A patent/CA1338618C/en not_active Expired - Fee Related
- 1988-11-02 EP EP92113037A patent/EP0513861B1/en not_active Expired - Lifetime
- 1988-11-02 AT AT92113037T patent/ATE149091T1/de not_active IP Right Cessation
-
1995
- 1995-02-17 HU HU95P/P00082P patent/HU210825A9/hu unknown
-
1997
- 1997-04-21 JP JP9103566A patent/JP2816337B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0315153B1 (en) | 1994-05-11 |
AU626271B2 (en) | 1992-07-30 |
EP0513861A1 (en) | 1992-11-19 |
AU2458888A (en) | 1989-05-04 |
IE63692B1 (en) | 1995-05-31 |
CA1338618C (en) | 1996-10-01 |
ES2052674T3 (es) | 1994-07-16 |
IE883305L (en) | 1989-05-03 |
EP0513861B1 (en) | 1997-02-26 |
NZ226811A (en) | 1991-06-25 |
ATE149091T1 (de) | 1997-03-15 |
JPH1053535A (ja) | 1998-02-24 |
DE3855807D1 (de) | 1997-04-03 |
DE3889521T2 (de) | 1994-12-08 |
ZA888209B (en) | 1990-07-25 |
JP2746272B2 (ja) | 1998-05-06 |
JP2816337B2 (ja) | 1998-10-27 |
EP0315153A2 (en) | 1989-05-10 |
DE3855807T2 (de) | 1997-06-12 |
DE3889521D1 (de) | 1994-06-16 |
JPH01157918A (ja) | 1989-06-21 |
EP0315153A3 (en) | 1989-08-09 |
HU210825A9 (en) | 1995-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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