DE3889521D1 - Impfstoff-Adjuvans. - Google Patents

Impfstoff-Adjuvans.

Info

Publication number
DE3889521D1
DE3889521D1 DE3889521T DE3889521T DE3889521D1 DE 3889521 D1 DE3889521 D1 DE 3889521D1 DE 3889521 T DE3889521 T DE 3889521T DE 3889521 T DE3889521 T DE 3889521T DE 3889521 D1 DE3889521 D1 DE 3889521D1
Authority
DE
Germany
Prior art keywords
emulsion
amount
optionally
toxic
vaccine adjuvant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3889521T
Other languages
English (en)
Other versions
DE3889521T2 (de
Inventor
Anthony Clifford Allison
Noelene Elva Byars
Cherng-Chyi Fu
Deborah Marilyn Lidgate
Philip Lewis Felgner
Linda Cheryl Foster
William Alfred Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Application granted granted Critical
Publication of DE3889521D1 publication Critical patent/DE3889521D1/de
Publication of DE3889521T2 publication Critical patent/DE3889521T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/5555—Muramyl dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
DE3889521T 1987-11-03 1988-11-02 Impfstoff-Adjuvans. Expired - Fee Related DE3889521T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11642587A 1987-11-03 1987-11-03

Publications (2)

Publication Number Publication Date
DE3889521D1 true DE3889521D1 (de) 1994-06-16
DE3889521T2 DE3889521T2 (de) 1994-12-08

Family

ID=22367122

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3889521T Expired - Fee Related DE3889521T2 (de) 1987-11-03 1988-11-02 Impfstoff-Adjuvans.
DE3855807T Expired - Fee Related DE3855807T2 (de) 1987-11-03 1988-11-02 Einen Tetra-Polyol enthaltendes Impfstoff-Adjuvans

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3855807T Expired - Fee Related DE3855807T2 (de) 1987-11-03 1988-11-02 Einen Tetra-Polyol enthaltendes Impfstoff-Adjuvans

Country Status (11)

Country Link
EP (2) EP0513861B1 (de)
JP (2) JP2746272B2 (de)
AT (1) ATE149091T1 (de)
AU (1) AU626271B2 (de)
CA (1) CA1338618C (de)
DE (2) DE3889521T2 (de)
ES (2) ES2052674T3 (de)
HU (1) HU210825A9 (de)
IE (1) IE63692B1 (de)
NZ (1) NZ226811A (de)
ZA (1) ZA888209B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU212924B (en) 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
US5709860A (en) * 1991-07-25 1998-01-20 Idec Pharmaceuticals Corporation Induction of cytotoxic T-lymphocyte responses
ES2053402B1 (es) * 1993-01-15 1995-02-01 Hipra Lab Sa Metodo de preparacion de vacunas inactivadas y vacunas vivas adyuvantadas asi como las vacunas obtenidas por dicho metodo.
DE4333376C2 (de) * 1993-09-30 1995-09-07 Gerbu Biotechnik Gmbh Mittel zur Steigerung der Ausbeute von Antikörpern in der Immunologie
GB9326253D0 (en) * 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
WO2000050006A2 (en) 1999-02-26 2000-08-31 Chiron Corporation Microemulsions with adsorbed macromoelecules and microparticles
US7824687B2 (en) 1999-08-20 2010-11-02 Sloan-Kettering Institute For Cancer Research Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof
WO2001014395A2 (en) 1999-08-20 2001-03-01 Sloan-Kettering Institute For Cancer Research Novel glycoconjugates, glycoamino, acids, intermediates thereto, and uses thereof
US7854934B2 (en) 1999-08-20 2010-12-21 Sloan-Kettering Institute For Cancer Research Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
US20020058040A1 (en) * 1999-12-23 2002-05-16 Stephen Grimes Stable immunogenic composition for frozen storage
FR2804026B1 (fr) * 2000-01-21 2004-06-11 Merial Sas Vaccination contre l'herpesvirose canine et vaccins
US7018638B2 (en) 2000-12-19 2006-03-28 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
MY129765A (en) * 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
MXPA05010697A (es) 2003-04-04 2005-12-12 Pfizer Prod Inc Emulsiones de aceite en agua microfluidizadas y composiciones de vacunas.
US9493580B2 (en) 2010-06-11 2016-11-15 Sloan-Kettering Institute For Cancer Research Multivalent glycopeptide constructs and uses thereof
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
JPH01501064A (ja) * 1986-09-22 1989-04-13 エモリ　ユニバーシティ ワクチンとその製法

Also Published As

Publication number Publication date
JP2746272B2 (ja) 1998-05-06
IE63692B1 (en) 1995-05-31
EP0315153A3 (en) 1989-08-09
EP0315153B1 (de) 1994-05-11
EP0513861B1 (de) 1997-02-26
ES2097840T3 (es) 1997-04-16
EP0513861A1 (de) 1992-11-19
AU626271B2 (en) 1992-07-30
NZ226811A (en) 1991-06-25
IE883305L (en) 1989-05-03
DE3855807T2 (de) 1997-06-12
AU2458888A (en) 1989-05-04
DE3889521T2 (de) 1994-12-08
HU210825A9 (en) 1995-08-28
CA1338618C (en) 1996-10-01
JP2816337B2 (ja) 1998-10-27
JPH01157918A (ja) 1989-06-21
EP0315153A2 (de) 1989-05-10
JPH1053535A (ja) 1998-02-24
DE3855807D1 (de) 1997-04-03
ATE149091T1 (de) 1997-03-15
ZA888209B (en) 1990-07-25
ES2052674T3 (es) 1994-07-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: BARZ, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 80803 MUENCHEN

8339 Ceased/non-payment of the annual fee