|
GB1062357A
(en)
|
1965-03-23 |
1967-03-22 |
Pfizer & Co C |
Quinazolone derivatives
|
|
US4032637A
(en)
|
1972-09-26 |
1977-06-28 |
Sandoz Ltd. |
Method of promoting sleep
|
|
US4337341A
(en)
|
1976-11-02 |
1982-06-29 |
Eli Lilly And Company |
4a-Aryl-octahydro-1H-2-pyrindines
|
|
GB8608335D0
(en)
|
1986-04-04 |
1986-05-08 |
Pfizer Ltd |
Pharmaceutically acceptable salts
|
|
US5453510A
(en)
|
1990-07-13 |
1995-09-26 |
Burroughs Wellcome Co. |
Neuromuscular blocking agents
|
|
JPH0741461A
(ja)
|
1993-05-27 |
1995-02-10 |
Eisai Co Ltd |
スルホン酸エステル誘導体
|
|
CA2214685C
(en)
|
1995-03-10 |
2008-05-20 |
Berlex Laboratories, Inc. |
Benzamidine derivatives their preparation and their use as anti-coagulants
|
|
GB9523675D0
(en)
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9619284D0
(en)
|
1996-09-16 |
1996-10-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9622363D0
(en)
|
1996-10-28 |
1997-01-08 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
WO1999031073A1
(en)
|
1997-12-15 |
1999-06-24 |
Yamanouchi Pharmaceutical Co., Ltd. |
Novel pyrimidine-5-carboxamide derivatives
|
|
US6303652B1
(en)
|
1998-08-21 |
2001-10-16 |
Hughes Institute |
BTK inhibitors and methods for their identification and use
|
|
EP1107957B1
(en)
|
1998-08-29 |
2006-10-18 |
AstraZeneca AB |
Pyrimidine compounds
|
|
AU762523C
(en)
|
1998-11-10 |
2004-02-12 |
Janssen Pharmaceutica N.V. |
HIV replication inhibiting pyrimidines
|
|
US6262088B1
(en)
|
1998-11-19 |
2001-07-17 |
Berlex Laboratories, Inc. |
Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants
|
|
US6127376A
(en)
|
1998-12-04 |
2000-10-03 |
Berlex Laboratories, Inc. |
Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
|
|
GB9828511D0
(en)
|
1998-12-24 |
1999-02-17 |
Zeneca Ltd |
Chemical compounds
|
|
US6495558B1
(en)
|
1999-01-22 |
2002-12-17 |
Amgen Inc. |
Kinase inhibitors
|
|
WO2000046203A2
(en)
|
1999-02-04 |
2000-08-10 |
Millennium Pharmaceuticals, Inc. |
G-protein coupled heptahelical receptor binding compounds and methods of use thereof
|
|
GB9914258D0
(en)
|
1999-06-18 |
1999-08-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
ATE247645T1
(de)
|
1999-06-29 |
2003-09-15 |
Egyt Gyogyszervegyeszeti Gyar |
Neue piperazinylalkylthiopyrimidine derivate, diese enthaltende pharmazeutische zusammenstellungen und verfahren zu deren herstellung
|
|
JP4794793B2
(ja)
|
1999-12-28 |
2011-10-19 |
ファーマコペイア， インコーポレイテッド |
Ｎ−ヘテロ環ＴＮＦ−α発現阻害剤
|
|
US20030004174A9
(en)
|
2000-02-17 |
2003-01-02 |
Armistead David M. |
Kinase inhibitors
|
|
GB0004888D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
GB0004887D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
EP1282607B1
(en)
|
2000-05-08 |
2015-11-11 |
Janssen Pharmaceutica NV |
Prodrugs of hiv replication inhibiting pyrimidines
|
|
GB0016877D0
(en)
|
2000-07-11 |
2000-08-30 |
Astrazeneca Ab |
Chemical compounds
|
|
CA2417500C
(en)
|
2000-07-28 |
2008-11-18 |
Georgetown University Medical Center |
Erbb-2 selective small molecule kinase inhibitors
|
|
US6908906B2
(en)
*
|
2001-02-09 |
2005-06-21 |
Sankyo Company, Limited |
Crystalline forms of pyrimidine nucleoside derivative
|
|
US6881737B2
(en)
|
2001-04-11 |
2005-04-19 |
Amgen Inc. |
Substituted triazinyl acrylamide derivatives and methods of use
|
|
JO3429B1
(ar)
|
2001-08-13 |
2019-10-20 |
Janssen Pharmaceutica Nv |
مشتقات برميدينات مثبطة فيروس الايدز
|
|
US6939874B2
(en)
|
2001-08-22 |
2005-09-06 |
Amgen Inc. |
Substituted pyrimidinyl derivatives and methods of use
|
|
WO2003030909A1
(en)
|
2001-09-25 |
2003-04-17 |
Bayer Pharmaceuticals Corporation |
2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer
|
|
EA007298B1
(ru)
|
2001-11-01 |
2006-08-25 |
Янссен Фармацевтика Н.В. |
Гетероариламины в качестве ингибиторов гликогенсинтаза-киназы 3-бета (ингибиторов gsk3)
|
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
US7459455B2
(en)
|
2002-02-08 |
2008-12-02 |
Smithkline Beecham Corporation |
Pyrimidine compounds
|
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
|
WO2003081210A2
(en)
|
2002-03-21 |
2003-10-02 |
Sunesis Pharmaceuticals, Inc. |
Identification of kinase inhibitors
|
|
US20040002395A1
(en)
|
2002-06-27 |
2004-01-01 |
Poynor Raymond L. |
Bridge weight for metal wood golf club
|
|
ATE451104T1
(de)
|
2002-07-29 |
2009-12-15 |
Rigel Pharmaceuticals Inc |
Verfahren zur behandlung oder pruvention von autoimmunkrankheiten mit 2,4-pyrimidindiamin- verbindungen
|
|
CA2439440A1
(en)
|
2002-09-05 |
2004-03-05 |
Emory University |
Treatment of tuberous sclerosis associated neoplasms
|
|
AU2002951853A0
(en)
|
2002-10-04 |
2002-10-24 |
Commonwealth Scientific And Industrial Research Organisation |
Crystal structure of erbb2 and uses thereof
|
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
|
KR20110132482A
(ko)
|
2003-02-07 |
2011-12-07 |
얀센 파마슈티카 엔.브이. |
Ｈｉｖ 감염 예방용 피리미딘 유도체
|
|
EP1597251B1
(en)
|
2003-02-20 |
2009-06-10 |
SmithKline Beecham Corporation |
Pyrimidine compounds
|
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
|
US20050014753A1
(en)
|
2003-04-04 |
2005-01-20 |
Irm Llc |
Novel compounds and compositions as protein kinase inhibitors
|
|
US20050043233A1
(en)
|
2003-04-29 |
2005-02-24 |
Boehringer Ingelheim International Gmbh |
Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
|
|
US7504396B2
(en)
|
2003-06-24 |
2009-03-17 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
ES2421139T3
(es)
|
2003-07-30 |
2013-08-29 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidindiamina para su uso en el tratamiento o la prevención de enfermedades autoinmunitarias
|
|
EP1663242B1
(en)
|
2003-08-07 |
2011-04-27 |
Rigel Pharmaceuticals, Inc. |
2,4-pyrimidinediamine compounds and uses as anti-proliferative agents
|
|
DK2287156T3
(da)
|
2003-08-15 |
2013-08-26 |
Novartis Ag |
2,4-Di(phenylamino)-pyrimidiner egnede i behandling af neoplastiske sygdomme, inflammatoriske lidelser og lidelser i immunsystemet
|
|
GB0321710D0
(en)
|
2003-09-16 |
2003-10-15 |
Novartis Ag |
Organic compounds
|
|
JP2007505858A
(ja)
|
2003-09-18 |
2007-03-15 |
ノバルティス アクチエンゲゼルシャフト |
増殖性障害の処置に有用な２，４−ジ（フェニルアミノ）ピリミジン
|
|
JP2007514775A
(ja)
|
2003-12-19 |
2007-06-07 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
１−（２，４−ピリミジンジアミノ）−２−シクロペンタンカルボキサイミド合成中間体の立体異性体および立体異性体混合物
|
|
KR101164541B1
(ko)
|
2004-01-12 |
2012-07-10 |
와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 |
선택적 키나제 저해제
|
|
AU2005206541A1
(en)
|
2004-01-16 |
2005-08-04 |
Wyeth |
Quinoline intermediates of receptor tyrosine kinase inhibitors and the synthesis thereof
|
|
EP1735268B1
(en)
|
2004-03-15 |
2012-02-15 |
Eli Lilly And Company |
Opioid receptor antagonists
|
|
WO2005105988A2
(en)
|
2004-04-28 |
2005-11-10 |
Vertex Pharmaceuticals Incorporated |
Crystal structure of human jak3 kinase domain complex and binding pockets thereof
|
|
CA2566531A1
(en)
|
2004-05-18 |
2005-12-15 |
Rigel Pharmaceuticals, Inc. |
Cycloalkyl substituted pyrimidinediamine compounds and their uses
|
|
EP1598343A1
(de)
|
2004-05-19 |
2005-11-23 |
Boehringer Ingelheim International GmbH |
2-Arylaminopyrimidine als PLK Inhibitoren
|
|
EP3042964A1
(en)
|
2004-06-04 |
2016-07-13 |
Genentech, Inc. |
Egfr mutations
|
|
US7521457B2
(en)
|
2004-08-20 |
2009-04-21 |
Boehringer Ingelheim International Gmbh |
Pyrimidines as PLK inhibitors
|
|
GB0419161D0
(en)
|
2004-08-27 |
2004-09-29 |
Novartis Ag |
Organic compounds
|
|
WO2006034473A2
(en)
|
2004-09-23 |
2006-03-30 |
Reddy Us Therapeutics, Inc. |
Novel pyrimidine compounds, process for their preparation and compositions containing them
|
|
CA2573976C
(en)
|
2004-09-30 |
2014-04-29 |
Tibotec Pharmaceuticals Ltd. |
Hiv inhibiting 5-carbo- or heterocyclic substituted pyrimidines
|
|
AU2005295788A1
(en)
|
2004-10-13 |
2006-04-27 |
Wyeth |
N-benzenesulfonyl substituted anilino-pyrimidine analogs
|
|
US20060088471A1
(en)
|
2004-10-20 |
2006-04-27 |
Proteolix, Inc. |
Compounds for enzyme inhibition
|
|
TW200628463A
(en)
|
2004-11-10 |
2006-08-16 |
Synta Pharmaceuticals Corp |
Heteroaryl compounds
|
|
GB2420559B
(en)
|
2004-11-15 |
2008-08-06 |
Rigel Pharmaceuticals Inc |
Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
|
|
WO2006068770A1
(en)
|
2004-11-24 |
2006-06-29 |
Rigel Pharmaceuticals, Inc. |
Spiro-2, 4-pyrimidinediamine compounds and their uses
|
|
MY169441A
(en)
|
2004-12-08 |
2019-04-11 |
Janssen Pharmaceutica Nv |
2,4, (4,6) pyrimidine derivatives
|
|
EP1841760B1
(en)
|
2004-12-30 |
2011-08-10 |
Exelixis, Inc. |
Pyrimidine derivatives as kinase modulators and method of use
|
|
EP1856053A1
(en)
|
2005-01-14 |
2007-11-21 |
Millennium Pharmaceuticals, Inc. |
Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity
|
|
EP2161275A1
(en)
|
2005-01-19 |
2010-03-10 |
Rigel Pharmaceuticals, Inc. |
Prodrugs of 2,4-pyrimidinediamine compounds and their uses
|
|
US8067175B2
(en)
|
2005-02-11 |
2011-11-29 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for detecting a drug resistant EGFR mutant
|
|
AU2006227628A1
(en)
|
2005-03-16 |
2006-09-28 |
Targegen, Inc. |
Pyrimidine compounds and methods of use
|
|
DE102005016634A1
(de)
|
2005-04-12 |
2006-10-19 |
Merck Patent Gmbh |
Neuartige Aza-Hetercyclen als Kinase-Inhibitoren
|
|
WO2007027238A2
(en)
|
2005-05-03 |
2007-03-08 |
Rigel Pharmaceuticals, Inc. |
Jak kinase inhibitors and their uses
|
|
WO2006124874A2
(en)
|
2005-05-12 |
2006-11-23 |
Kalypsys, Inc. |
Inhibitors of b-raf kinase
|
|
WO2006128172A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating b cell regulated autoimmune disorders
|
|
WO2006128129A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating cancer
|
|
WO2006129100A1
(en)
|
2005-06-03 |
2006-12-07 |
Glaxo Group Limited |
Novel compounds
|
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
US7491732B2
(en)
|
2005-06-08 |
2009-02-17 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
|
JP5376950B2
(ja)
|
2005-10-21 |
2013-12-25 |
エクセリクシス， インク． |
カゼインキナーゼｉｉ（ｃｋ２）モジュレーターとしてのピリミジオン類
|
|
NZ592990A
(en)
|
2005-11-01 |
2013-01-25 |
Targegen Inc |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
WO2007056151A2
(en)
|
2005-11-03 |
2007-05-18 |
Irm Llc |
Protein kinase inhbitors
|
|
US7713987B2
(en)
|
2005-12-06 |
2010-05-11 |
Rigel Pharmaceuticals, Inc. |
Pyrimidine-2,4-diamines and their uses
|
|
US20080318989A1
(en)
|
2005-12-19 |
2008-12-25 |
Burdick Daniel J |
Pyrimidine Kinase Inhibitors
|
|
TW200736232A
(en)
|
2006-01-26 |
2007-10-01 |
Astrazeneca Ab |
Pyrimidine derivatives
|
|
KR20080110998A
(ko)
|
2006-01-30 |
2008-12-22 |
엑셀리시스, 인코포레이티드 |
Ｊａｋ２ 조절자로서 ４아릴２아미노피리미딘 또는 4아릴２아미노알킬피리미딘 및 이들을 포함하는 약제학적 조성물
|
|
US7659280B2
(en)
|
2006-02-17 |
2010-02-09 |
Rigel Pharmaceuticals, Inc. |
2,4-pyrimidinediamine compounds for treating or preventing autoimmune diseases
|
|
WO2007098507A2
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
ATE482953T1
(de)
|
2006-03-30 |
2010-10-15 |
Tibotec Pharm Ltd |
Hiv-inhibierende 5-(hydroxymethylen- und aminomethylen) substituierte pyrimidine
|
|
BRPI0709690B8
(pt)
|
2006-03-30 |
2021-05-25 |
Janssen R & D Ireland |
5-amido pirimidinas substituídas e composição farmacêutica que as compreende
|
|
GB0608386D0
(en)
|
2006-04-27 |
2006-06-07 |
Senexis Ltd |
Compounds
|
|
CA2650035C
(en)
|
2006-04-27 |
2015-02-03 |
Intezyne Technologies, Inc. |
Poly (ethylene glycol) containing chemically disparate endgroups
|
|
DE102006027156A1
(de)
|
2006-06-08 |
2007-12-13 |
Bayer Schering Pharma Ag |
Sulfimide als Proteinkinaseinhibitoren
|
|
CA2656290A1
(en)
|
2006-07-05 |
2008-01-10 |
Exelixis, Inc. |
Methods of using igf1r and abl kinase modulators
|
|
WO2008009458A1
(en)
|
2006-07-21 |
2008-01-24 |
Novartis Ag |
2, 4 -di (arylaminio) -pyrimidine-5-carboxamide compounds as jak kinases inhibitors
|
|
DE102006041382A1
(de)
|
2006-08-29 |
2008-03-20 |
Bayer Schering Pharma Ag |
Carbamoyl-Sulfoximide als Proteinkinaseinhibitoren
|
|
PT2201840E
(pt)
|
2006-09-22 |
2012-02-14 |
Pharmacyclics Inc |
Inibidores da tirosina quinase de bruton
|
|
WO2008049123A2
(en)
|
2006-10-19 |
2008-04-24 |
Rigel Pharmaceuticals, Inc. |
2,4-pyrimidinediamine derivatives as inhibitors of jak kinases for the treatment of autoimmune diseases
|
|
EP2089391B1
(en)
|
2006-11-03 |
2013-01-16 |
Pharmacyclics, Inc. |
Bruton's tyrosine kinase activity probe and method of using
|
|
US8163902B2
(en)
|
2006-11-21 |
2012-04-24 |
Rigel Pharmaceuticals, Inc. |
Prodrugs of 2,4-pyrimidinediamine compounds and their uses
|
|
KR101149295B1
(ko)
|
2006-12-08 |
2012-07-05 |
아이알엠 엘엘씨 |
단백질 키나제 억제제로서의 화합물
|
|
CA2670645A1
(en)
|
2006-12-19 |
2008-07-03 |
Genentech, Inc. |
Pyrimidine kinase inhibitors
|
|
EP1939185A1
(de)
|
2006-12-20 |
2008-07-02 |
Bayer Schering Pharma Aktiengesellschaft |
Neuartige Hetaryl-Phenylendiamin-Pyrimidine als Proteinkinaseinhibitoren zur Behandlung von Krebs
|
|
KR20090094073A
(ko)
|
2006-12-29 |
2009-09-03 |
티보텍 파마슈티칼즈 리미티드 |
Ｈｉｖ를 억제하는 6-치환된 피리미딘
|
|
CN101573342A
(zh)
|
2006-12-29 |
2009-11-04 |
泰博特克药品有限公司 |
抑制hiv的5,6-取代的嘧啶类化合物
|
|
AR065015A1
(es)
|
2007-01-26 |
2009-05-13 |
Smithkline Beecham Corp |
Derivados de antranilamida, composiciones farmaceuticas que los contienen, y usos para el tratamiento del cancer
|
|
AU2008210266B2
(en)
|
2007-01-31 |
2013-09-05 |
Ym Biosciences Australia Pty Ltd |
Thiopyrimidine-based compounds and uses thereof
|
|
JP4221470B2
(ja)
|
2007-02-01 |
2009-02-12 |
トヨタ自動車株式会社 |
電動車両制御装置及び電動車両制御方法
|
|
DE102007010801A1
(de)
|
2007-03-02 |
2008-09-04 |
Bayer Cropscience Ag |
Diaminopyrimidine als Fungizide
|
|
CN101686675A
(zh)
|
2007-03-20 |
2010-03-31 |
史密丝克莱恩比彻姆公司 |
化合物
|
|
CN101677554A
(zh)
|
2007-03-20 |
2010-03-24 |
史密丝克莱恩比彻姆公司 |
化合物
|
|
US7947698B2
(en)
|
2007-03-23 |
2011-05-24 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
|
US7834024B2
(en)
|
2007-03-26 |
2010-11-16 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
|
US20120065201A1
(en)
|
2007-03-28 |
2012-03-15 |
Pharmacyclics, Inc. |
Inhibitors of bruton's tyrosine kinase
|
|
US8809273B2
(en)
|
2007-03-28 |
2014-08-19 |
Pharmacyclics, Inc. |
Inhibitors of Bruton's tyrosine kinase
|
|
CA2689989A1
(en)
|
2007-06-04 |
2008-12-11 |
Avila Therapeutics, Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2009012421A1
(en)
|
2007-07-17 |
2009-01-22 |
Rigel Pharmaceuticals, Inc. |
Cyclic amine substituted pyrimidinediamines as pkc inhibitors
|
|
WO2009017838A2
(en)
|
2007-08-01 |
2009-02-05 |
Exelixis, Inc. |
Combinations of jak-2 inhibitors and other agents
|
|
WO2009032703A1
(en)
|
2007-08-28 |
2009-03-12 |
Irm Llc |
2- (het) arylamino-6-aminopyridine derivatives and fused forms thereof as anaplastic lymphoma kinase inhibitors
|
|
CA2696824A1
(en)
|
2007-08-28 |
2009-03-12 |
Irm Llc |
Compounds and compositions as kinase inhibitors
|
|
WO2009029682A1
(en)
|
2007-08-28 |
2009-03-05 |
Rigel Pharmaceuticals, Inc. |
Combination therapy with syk kinase inhibitor
|
|
US7989465B2
(en)
|
2007-10-19 |
2011-08-02 |
Avila Therapeutics, Inc. |
4,6-disubstituted pyrimidines useful as kinase inhibitors
|
|
CA2702674C
(en)
|
2007-10-19 |
2016-05-03 |
Avila Therapeutics, Inc. |
Heteroaryl compounds and uses thereof
|
|
CA2710118A1
(en)
|
2007-12-20 |
2009-07-02 |
Cellzome Limited |
Sulfamides as zap-70 inhibitors
|
|
AU2009215430B2
(en)
|
2008-02-22 |
2015-02-12 |
Rigel Pharmaceuticals, Inc. |
Use of 2,4-pyrimidinediamines for the treatment of atherosclerosis
|
|
EP2276747A1
(en)
|
2008-03-11 |
2011-01-26 |
Cellzome Limited |
Sulfonamides as zap-70 inhibitors
|
|
US8205348B2
(en)
|
2008-03-19 |
2012-06-26 |
Zashiki-Warashi Manufacturing Inc. |
Tile spacer and holder therefor
|
|
CL2009000600A1
(es)
|
2008-03-20 |
2010-05-07 |
Bayer Cropscience Ag |
Uso de compuestos de diaminopirimidina como agentes fitosanitarios; compuestos de diaminopirimidina; su procedimiento de preparacion; agente que los contiene; procedimiento para la preparacion de dicho agente; y procedimiento para combatir plagas de animales y/u hongos dañinos patogenos de plantas.
|
|
WO2009127642A2
(en)
|
2008-04-15 |
2009-10-22 |
Cellzome Limited |
Use of lrrk2 inhibitors for neurodegenerative diseases
|
|
US8138339B2
(en)
|
2008-04-16 |
2012-03-20 |
Portola Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
|
JP2011518836A
(ja)
|
2008-04-24 |
2011-06-30 |
インサイト・コーポレイション |
大環状化合物およびそれらのキナーゼ阻害剤としての使用
|
|
PL2300013T5
(pl)
|
2008-05-21 |
2025-04-28 |
Takeda Pharmaceutical Company Limited |
Pochodne fosforu jako inhibitor kinazy
|
|
TWI458721B
(zh)
|
2008-06-27 |
2014-11-01 |
Celgene Avilomics Res Inc |
雜芳基化合物及其用途
|
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
AU2009270856B2
(en)
|
2008-07-16 |
2013-07-25 |
Pharmacyclics Llc |
Inhibitors of Bruton's tyrosine kinase for the treatment of solid tumors
|
|
WO2010025833A1
(de)
|
2008-09-03 |
2010-03-11 |
Bayer Cropscience Ag |
Alkoxy- und alkylthio-substituierte anilinopyrimidine
|
|
US20110245156A1
(en)
|
2008-12-09 |
2011-10-06 |
Cytokine Pharmasciences, Inc. |
Novel antiviral compounds, compositions, and methods of use
|
|
CA2965031C
(en)
|
2009-01-15 |
2018-12-04 |
F. Hoffmann-La Roche Ag |
Antibodies against phosphorylated tyrosines on erythropoietin receptor (epor)
|
|
WO2010112210A1
(en)
|
2009-04-03 |
2010-10-07 |
Cellzome Ag |
Methods for the identification of kinase interacting molecules and for the purification of kinase proteins
|
|
KR101705158B1
(ko)
*
|
2009-05-05 |
2017-02-09 |
다나-파버 캔서 인스티튜트 인크. |
Ｅｇｆｒ 억제제 및 질환 치료방법
|
|
DK2428508T3
(en)
|
2009-05-08 |
2016-02-01 |
Astellas Pharma Inc |
Diamino heterocyclic carboxamide COMPOUND
|
|
CA2763720A1
(en)
|
2009-06-18 |
2010-12-23 |
Cellzome Limited |
Sulfonamides and sulfamides as zap-70 inhibitors
|
|
US7741330B1
(en)
|
2009-10-12 |
2010-06-22 |
Pharmacyclics, Inc. |
Pyrazolo-pyrimidine inhibitors of Bruton's tyrosine kinase
|
|
WO2011079231A1
(en)
|
2009-12-23 |
2011-06-30 |
Gatekeeper Pharmaceutical, Inc. |
Compounds that modulate egfr activity and methods for treating or preventing conditions therewith
|
|
WO2011140338A1
(en)
|
2010-05-05 |
2011-11-10 |
Gatekeeper Pharmaceuticals, Inc. |
Compounds that modulate egfr activity and methods for treating or preventing conditions therewith
|
|
US20120071497A1
(en)
|
2010-06-03 |
2012-03-22 |
Pharmacyclics, Inc. |
Methods of treating abc-dlbcl using inhibitors of bruton's tyrosine kinase
|
|
EA201890869A3
(ru)
|
2010-06-03 |
2019-03-29 |
Фармасайкликс, Инк. |
Применение ингибиторов тирозинкиназы брутона (btk)
|
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
|
RU2013109393A
(ru)
|
2010-08-10 |
2014-09-20 |
Сэлджин Авиаломикс Ресеарч, Инк. |
Безилатная соль ингибитора втк
|
|
EP2635285B1
(en)
|
2010-11-01 |
2017-05-03 |
Celgene Avilomics Research, Inc. |
Heteroaryl compounds and uses thereof
|
|
US20130317029A1
(en)
|
2010-11-01 |
2013-11-28 |
Portola Pharmaceuticals, Inc. |
Oxypyrimidines as syk modulators
|
|
CA2815858C
(en)
|
2010-11-01 |
2018-10-16 |
Celgene Avilomics Research, Inc. |
Heterocyclic compounds and uses thereof
|
|
EP2637502B1
(en)
|
2010-11-10 |
2018-01-10 |
Celgene CAR LLC |
Mutant-selective egfr inhibitors and uses thereof
|
|
EP2704572B1
(en)
|
2011-05-04 |
2015-12-30 |
Ariad Pharmaceuticals, Inc. |
Compounds for inhibiting cell proliferation in egfr-driven cancers
|
|
ES2770550T3
(es)
|
2011-05-17 |
2020-07-02 |
Univ California |
Inhibidores de quinasa
|
|
BR112014022789B1
(pt)
|
2012-03-15 |
2022-04-19 |
Celgene Car Llc |
Formas sólidas de um inibidor de quinase de receptor do fator de crescimento epidérmico, composição farmacêutica e usos do mesmo
|
|
RU2711077C9
(ru)
|
2012-03-15 |
2020-08-11 |
Селджен Кар Ллс |
Соли ингибитора киназы рецептора эпидермального фактора роста
|
|
CA2890111A1
(en)
|
2012-11-02 |
2014-05-08 |
Pharmacyclics, Inc. |
Tec family kinase inhibitor adjuvant therapy
|
|
JP2016518408A
(ja)
|
2013-05-06 |
2016-06-23 |
クロヴィス・オンコロジー，インコーポレーテッド |
上皮増殖因子受容体キナーゼ阻害剤の塩
|