JP2015509948A5 - - Google Patents
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- JP2015509948A5 JP2015509948A5 JP2014558901A JP2014558901A JP2015509948A5 JP 2015509948 A5 JP2015509948 A5 JP 2015509948A5 JP 2014558901 A JP2014558901 A JP 2014558901A JP 2014558901 A JP2014558901 A JP 2014558901A JP 2015509948 A5 JP2015509948 A5 JP 2015509948A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- chain variable
- variable region
- antibody
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261603203P | 2012-02-24 | 2012-02-24 | |
| US61/603,203 | 2012-02-24 | ||
| PCT/US2013/027476 WO2013126810A1 (en) | 2012-02-24 | 2013-02-22 | Anti sez6 antibodies and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018052506A Division JP2018127469A (ja) | 2012-02-24 | 2018-03-20 | 抗ｓｅｚ６抗体及び使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015509948A JP2015509948A (ja) | 2015-04-02 |
| JP2015509948A5 true JP2015509948A5 (https=) | 2016-04-14 |
| JP6401060B2 JP6401060B2 (ja) | 2018-10-03 |
Family
ID=47790548
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014558901A Expired - Fee Related JP6401060B2 (ja) | 2012-02-24 | 2013-02-22 | 抗ｓｅｚ６抗体及び使用方法 |
| JP2018052506A Pending JP2018127469A (ja) | 2012-02-24 | 2018-03-20 | 抗ｓｅｚ６抗体及び使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018052506A Pending JP2018127469A (ja) | 2012-02-24 | 2018-03-20 | 抗ｓｅｚ６抗体及び使用方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9676850B2 (https=) |
| EP (2) | EP2817339B1 (https=) |
| JP (2) | JP6401060B2 (https=) |
| KR (1) | KR102099073B1 (https=) |
| CN (2) | CN108383909B (https=) |
| AU (3) | AU2013203506B2 (https=) |
| CA (1) | CA2865415C (https=) |
| CL (2) | CL2014002237A1 (https=) |
| CO (1) | CO7151485A2 (https=) |
| ES (1) | ES2741936T3 (https=) |
| IL (1) | IL234208B (https=) |
| MX (2) | MX373141B (https=) |
| MY (1) | MY178120A (https=) |
| NZ (1) | NZ631197A (https=) |
| PE (1) | PE20150091A1 (https=) |
| PH (2) | PH12020500604A1 (https=) |
| RU (1) | RU2691698C2 (https=) |
| SG (2) | SG11201405130UA (https=) |
| WO (1) | WO2013126810A1 (https=) |
| ZA (1) | ZA201406967B (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2865415C (en) * | 2012-02-24 | 2022-06-21 | Stem Centrx, Inc. | Anti sez6 antibodies and methods of use |
| US11531028B2 (en) * | 2013-05-10 | 2022-12-20 | Nordic Bioscience A/S | Collagen type X alpha-1 assay |
| AU2014312215B2 (en) * | 2013-08-28 | 2020-02-27 | Abbvie Stemcentrx Llc | Site-specific antibody conjugation methods and compositions |
| AU2014312310A1 (en) | 2013-08-28 | 2016-04-07 | Abbvie Stemcentrx Llc | Novel SEZ6 modulators and methods of use |
| CN105828841A (zh) | 2013-11-04 | 2016-08-03 | 辉瑞大药厂 | 抗-efna4抗体-药物缀合物 |
| SG11201604503XA (en) * | 2013-12-03 | 2016-07-28 | Agency Science Tech & Res | Cytotoxic antibody |
| EP3981874A1 (en) | 2014-01-29 | 2022-04-13 | KM Biologics Co., Ltd. | Anti-transthyretin human antibody |
| EP3101131B1 (en) * | 2014-01-29 | 2020-08-19 | KM Biologics Co., Ltd. | Anti-transthyretin humanized antibody |
| PE20161209A1 (es) | 2014-02-21 | 2016-11-10 | Abbvie Stemcentrx Llc | Conjugados de anticuerpos anti-drosophila similar a delta 3 (anti-dll3) y medicamentos para usarse en el tratamiento contra melanoma |
| US9631024B2 (en) | 2014-06-23 | 2017-04-25 | Bionomics, Inc. | Antibodies that bind LGR4, their use in inhibiting neoplastic cells and in treating tumors |
| TW201617368A (zh) * | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗ｍｆｉ２抗體及使用方法 |
| US9688750B2 (en) | 2014-10-07 | 2017-06-27 | Ann And Robert H. Lurie Children's Hospital Of Chicago | Anti-nodal antibodies and methods of using same |
| CN108136015A (zh) * | 2015-08-20 | 2018-06-08 | 艾伯维施特姆森特克斯有限责任公司 | 抗dll3抗体药物缀合物以及使用方法 |
| US11294038B2 (en) | 2015-10-06 | 2022-04-05 | Pioneer Corporation | Light control device, light control method and program |
| US20180346571A1 (en) * | 2015-11-17 | 2018-12-06 | Oncomed Pharmaceuticals, Inc. | Pd-l1-binding agents and uses thereof |
| WO2017152088A1 (en) | 2016-03-04 | 2017-09-08 | JN Biosciences, LLC | Antibodies to tigit |
| US11214612B2 (en) | 2016-10-14 | 2022-01-04 | Nima Acquisition, Llc | Anti-gliadin antibodies, encoding nucleic acids and methods of detecting gliadin |
| CA3040421A1 (en) * | 2016-10-19 | 2018-04-26 | Novelogics Biotechnology, Inc. | Antibodies to mica and micb proteins |
| WO2018107116A1 (en) * | 2016-12-09 | 2018-06-14 | Abbvie Stemcentrx Llc | Methods of reducing toxicity of antibody drug conjugates, and compositions produced thereby |
| CN118271442A (zh) | 2016-12-23 | 2024-07-02 | 蓝鳍生物医药公司 | 抗sez6l2抗体和抗体药物缀合物 |
| EP3424528A1 (de) * | 2017-07-07 | 2019-01-09 | AVA Lifescience GmbH | Biologische bindemoleküle |
| EP3774898A4 (en) * | 2018-04-13 | 2022-01-26 | Dingfu Biotarget Co., Ltd. | ANTI-CD27 ANTIBODIES AND USE THEREOF |
| US20210196834A1 (en) * | 2018-05-30 | 2021-07-01 | Abbvie Stemcentrx Llc | Anti-sez6 antibody drug conjugates and methods of use |
| WO2020013644A1 (ko) * | 2018-07-11 | 2020-01-16 | 고려대학교 산학협력단 | Smo 단백질의 특이적 에피토프, 이를 인지하는 항체 및 이를 포함하는 조성물 |
| TW202537643A (zh) | 2018-07-31 | 2025-10-01 | 日商第一三共股份有限公司 | 抗體-藥物結合物之用途 |
| CN115991781A (zh) * | 2018-08-24 | 2023-04-21 | 江苏恒瑞医药股份有限公司 | 结合人il-4r的抗体、其抗原结合片段及其医药用途 |
| BR112022024221A2 (pt) | 2020-06-02 | 2022-12-20 | Arcus Biosciences Inc | Anticorpos para tigit |
| CN114106176B (zh) * | 2020-09-01 | 2024-04-09 | 深圳市菲鹏生物治疗股份有限公司 | Cd22抗体及其应用 |
| US20230287090A1 (en) * | 2020-09-02 | 2023-09-14 | The Feinstein Institutes For Medical Research | USE OF SARS-CoV-2 RECEPTOR BINDING MOTIF (RBM)-REACTIVE MONOCLONAL ANTIBODIES TO TREAT COVID-19 |
| AU2021386367A1 (en) | 2020-11-24 | 2023-06-22 | Les Laboratoires Servier | Bcl-xl inhibitor antibody-drug conjugates and methods of use thereof |
| CN114790241B (zh) * | 2021-01-26 | 2024-12-13 | 北京免疫方舟医药科技有限公司 | 抗tigit抗体及其应用 |
| CN113307875B (zh) * | 2021-06-10 | 2022-09-02 | 福州迈新生物技术开发有限公司 | 抗TCRβF1蛋白单克隆抗体及其细胞株、制备方法和应用 |
| WO2023019174A2 (en) * | 2021-08-11 | 2023-02-16 | Apollos Diagnostics, Llc | Antibodies to sars-cov-2 |
| CN120787162A (zh) | 2022-05-20 | 2025-10-14 | 诺华股份有限公司 | 抗肿瘤化合物的抗体-药物缀合物及其使用方法 |
| US20260061065A1 (en) | 2022-05-20 | 2026-03-05 | Novartis Ag | Antibody drug conjugates |
| CN115975036B (zh) * | 2022-08-18 | 2023-06-09 | 北京诺赛国际医学研究院 | 包含干细胞的药物组合物及其治疗癌症的用途 |
| WO2024230742A1 (zh) | 2023-05-08 | 2024-11-14 | 上海翰森生物医药科技有限公司 | 一种抗体或其抗原结合片段、抗体-药物偶联物及其应用 |
| CN117736331B (zh) * | 2024-02-04 | 2024-05-07 | 南昌大学第一附属医院 | 一种特异性结合psma胞外段的单克隆抗体及其应用 |
| WO2025167503A1 (en) * | 2024-02-05 | 2025-08-14 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Anti-sez6/b7h3 antibodies and uses thereof |
| CN119409821B (zh) * | 2024-10-18 | 2025-07-29 | 北京大学第一医院(北京大学第一临床医学院) | 一种抗sez6纳米抗体或抗原结合片段与应用 |
| CN120365421B (zh) * | 2025-04-24 | 2025-11-04 | 成都古格尔生物技术有限公司 | 一种特异性抗sez6靶点的全人源抗体及其制备方法和应用 |
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| AU2014312215B2 (en) * | 2013-08-28 | 2020-02-27 | Abbvie Stemcentrx Llc | Site-specific antibody conjugation methods and compositions |
| AU2014312310A1 (en) * | 2013-08-28 | 2016-04-07 | Abbvie Stemcentrx Llc | Novel SEZ6 modulators and methods of use |
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2013
- 2013-02-22 CA CA2865415A patent/CA2865415C/en active Active
- 2013-02-22 KR KR1020147026846A patent/KR102099073B1/ko not_active Expired - Fee Related
- 2013-02-22 WO PCT/US2013/027476 patent/WO2013126810A1/en not_active Ceased
- 2013-02-22 US US14/380,665 patent/US9676850B2/en active Active
- 2013-02-22 SG SG11201405130UA patent/SG11201405130UA/en unknown
- 2013-02-22 EP EP13707529.7A patent/EP2817339B1/en active Active
- 2013-02-22 PE PE2014001301A patent/PE20150091A1/es active IP Right Grant
- 2013-02-22 ES ES13707529T patent/ES2741936T3/es active Active
- 2013-02-22 SG SG10201801444WA patent/SG10201801444WA/en unknown
- 2013-02-22 JP JP2014558901A patent/JP6401060B2/ja not_active Expired - Fee Related
- 2013-02-22 PH PH1/2020/500604A patent/PH12020500604A1/en unknown
- 2013-02-22 CN CN201810153825.5A patent/CN108383909B/zh not_active Expired - Fee Related
- 2013-02-22 CN CN201380010534.6A patent/CN104334580B/zh not_active Expired - Fee Related
- 2013-02-22 EP EP19154773.6A patent/EP3539985A1/en not_active Withdrawn
- 2013-02-22 MX MX2014010094A patent/MX373141B/es active IP Right Grant
- 2013-02-22 NZ NZ631197A patent/NZ631197A/en not_active IP Right Cessation
- 2013-02-22 AU AU2013203506A patent/AU2013203506B2/en not_active Ceased
- 2013-02-22 RU RU2014138420A patent/RU2691698C2/ru active
- 2013-02-22 MY MYPI2014002467A patent/MY178120A/en unknown
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2014
- 2014-08-19 IL IL234208A patent/IL234208B/en active IP Right Grant
- 2014-08-21 MX MX2020003713A patent/MX2020003713A/es unknown
- 2014-08-22 CL CL2014002237A patent/CL2014002237A1/es unknown
- 2014-08-26 PH PH12014501914A patent/PH12014501914B1/en unknown
- 2014-09-23 ZA ZA2014/06967A patent/ZA201406967B/en unknown
- 2014-09-23 CO CO14210871A patent/CO7151485A2/es unknown
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2016
- 2016-09-07 AU AU2016225828A patent/AU2016225828B2/en not_active Ceased
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2017
- 2017-06-05 US US15/614,548 patent/US10533051B2/en not_active Expired - Fee Related
- 2017-11-08 CL CL2017002823A patent/CL2017002823A1/es unknown
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2018
- 2018-03-20 JP JP2018052506A patent/JP2018127469A/ja active Pending
- 2018-08-31 AU AU2018223053A patent/AU2018223053B2/en not_active Expired - Fee Related
-
2019
- 2019-12-12 US US16/712,324 patent/US20200181256A1/en not_active Abandoned
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