JP2015506355A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015506355A5 JP2015506355A5 JP2014549480A JP2014549480A JP2015506355A5 JP 2015506355 A5 JP2015506355 A5 JP 2015506355A5 JP 2014549480 A JP2014549480 A JP 2014549480A JP 2014549480 A JP2014549480 A JP 2014549480A JP 2015506355 A5 JP2015506355 A5 JP 2015506355A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- heterocyclyl
- substituted
- carbocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *C(N(*)I[Al]C(C1)CN1[Al])=O Chemical compound *C(N(*)I[Al]C(C1)CN1[Al])=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11196170 | 2011-12-30 | ||
| EP11196170.2 | 2011-12-30 | ||
| PCT/EP2012/077027 WO2013098375A1 (en) | 2011-12-30 | 2012-12-28 | New azetidine derivatives, pharmaceutical compositions and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015506355A JP2015506355A (ja) | 2015-03-02 |
| JP2015506355A5 true JP2015506355A5 (enExample) | 2016-02-25 |
| JP6130399B2 JP6130399B2 (ja) | 2017-05-17 |
Family
ID=47553036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014549480A Expired - Fee Related JP6130399B2 (ja) | 2011-12-30 | 2012-12-28 | 新規アゼチジン誘導体、医薬組成物およびそれらの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8623860B2 (enExample) |
| EP (1) | EP2797884B1 (enExample) |
| JP (1) | JP6130399B2 (enExample) |
| KR (1) | KR20140115307A (enExample) |
| CN (1) | CN104093705A (enExample) |
| AU (1) | AU2012360797A1 (enExample) |
| BR (1) | BR112014015845A8 (enExample) |
| CA (1) | CA2861013A1 (enExample) |
| EA (1) | EA201400771A1 (enExample) |
| IL (1) | IL232914A0 (enExample) |
| MX (1) | MX2014007897A (enExample) |
| PH (1) | PH12014501514A1 (enExample) |
| WO (1) | WO2013098375A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2707361T1 (sl) | 2011-05-10 | 2017-12-29 | Gilead Sciences, Inc. | Zlite heterociklične spojine kot modulatorji natrijevega kanala |
| NO3175985T3 (enExample) | 2011-07-01 | 2018-04-28 | ||
| TWI549944B (zh) | 2011-07-01 | 2016-09-21 | 吉李德科學股份有限公司 | 作為離子通道調節劑之稠合雜環化合物 |
| WO2014061693A1 (ja) * | 2012-10-17 | 2014-04-24 | 塩野義製薬株式会社 | 新規非芳香族炭素環又は非芳香族複素環誘導体 |
| US20160220557A1 (en) | 2013-09-12 | 2016-08-04 | Pfizer Inc. | Use of acetyl-coa carboxylase inhibitors for treating acne vulgaris |
| CN103483273B (zh) * | 2013-09-12 | 2015-11-25 | 浙江工业大学 | 6-甲基-5-氟-2,4-嘧啶二胺类化合物及其制备与应用 |
| US10150728B2 (en) | 2013-10-17 | 2018-12-11 | Shionogi & Co., Ltd. | Alkylene derivatives |
| AU2015229188A1 (en) | 2014-03-13 | 2016-09-29 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing CFTR activity |
| WO2015138934A1 (en) | 2014-03-13 | 2015-09-17 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing cftr activity |
| EP3157917B1 (en) | 2014-06-19 | 2020-03-18 | Proteostasis Therapeutics, Inc. | Compounds, compositions and methods of increasing cftr activity |
| CA2971855A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc. | Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| WO2016105468A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc. | Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| MA41253A (fr) | 2014-12-23 | 2017-10-31 | Proteostasis Therapeutics Inc | Composés, compositions et procédés pour augmenter l'activité du cftr |
| WO2016105477A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc | Derivatives of 5-phenyl- or 5-heteroarylthiazol-2-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| EP3325474A1 (en) | 2015-07-24 | 2018-05-30 | Proteostasis Therapeutics, Inc. | Compounds, compositions and methods of increasing cftr activity |
| JP6929276B2 (ja) | 2015-10-06 | 2021-09-01 | プロテオステイシス セラピューティクス，インコーポレイテッド | 化合物、医薬的に許容される塩又はその立体異性体及び医薬組成物 |
| US10662207B2 (en) | 2016-04-07 | 2020-05-26 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for modulating CFTR |
| WO2017223188A1 (en) | 2016-06-21 | 2017-12-28 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing cftr activity |
| CN110776504B (zh) * | 2019-11-29 | 2021-07-30 | 扬州工业职业技术学院 | 一种苯异噁唑乙氧基环丁胺衍生物及其制备方法与应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1478437B1 (en) | 2002-02-27 | 2005-08-31 | Pfizer Products Inc. | Acc inhibitors |
| DE102005055726A1 (de) | 2005-11-23 | 2007-08-30 | Sanofi-Aventis Deutschland Gmbh | Hydroxy-substituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| MX2008008337A (es) | 2005-12-21 | 2008-09-03 | Schering Corp | Fenoxipiperidinas y sus analogos utiles como antagonistas de histamina h3. |
| JP2009539884A (ja) * | 2006-06-12 | 2009-11-19 | メルク フロスト カナダ リミテツド | ステアロイル−コエンザイムａデルタ−９デサチュラーゼのインヒビターとしてのアゼチジン誘導体 |
| US20110183958A1 (en) | 2008-10-17 | 2011-07-28 | Merck Frosst Canada Ltd. | Azetidine derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| US20100280067A1 (en) | 2009-04-30 | 2010-11-04 | Pakala Kumara Savithru Sarma | Inhibitors of acetyl-coa carboxylase |
| UA108102C2 (uk) | 2010-04-27 | 2015-03-25 | Біциклічні похідні і їх застосування як інгібіторів асс | |
| MX2012013130A (es) * | 2010-05-13 | 2013-04-11 | Amgen Inc | Compuestos heterociclicos de nitrogeno utiles como inhibidores de pde10. |
-
2012
- 2012-12-14 US US13/714,525 patent/US8623860B2/en active Active
- 2012-12-28 CA CA2861013A patent/CA2861013A1/en not_active Abandoned
- 2012-12-28 BR BR112014015845A patent/BR112014015845A8/pt not_active Application Discontinuation
- 2012-12-28 EA EA201400771A patent/EA201400771A1/ru unknown
- 2012-12-28 EP EP12813379.0A patent/EP2797884B1/en active Active
- 2012-12-28 MX MX2014007897A patent/MX2014007897A/es unknown
- 2012-12-28 JP JP2014549480A patent/JP6130399B2/ja not_active Expired - Fee Related
- 2012-12-28 CN CN201280068972.3A patent/CN104093705A/zh active Pending
- 2012-12-28 WO PCT/EP2012/077027 patent/WO2013098375A1/en not_active Ceased
- 2012-12-28 AU AU2012360797A patent/AU2012360797A1/en not_active Abandoned
- 2012-12-28 KR KR1020147018007A patent/KR20140115307A/ko not_active Withdrawn
-
2014
- 2014-06-02 IL IL232914A patent/IL232914A0/en unknown
- 2014-06-30 PH PH12014501514A patent/PH12014501514A1/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015506355A5 (enExample) | ||
| CN105745206B (zh) | 用于治疗疾病的葡萄糖神经酰胺合成酶抑制剂 | |
| JP6648137B2 (ja) | ヘテロ環式誘導体およびその使用 | |
| EP3083639B1 (en) | Cyclic sulfone and sulfoximine analogs and uses thereof | |
| JP4722851B2 (ja) | キノリンカリウムチャネル阻害剤 | |
| JP4719151B2 (ja) | イソキノリノンカリウムチャネル阻害剤 | |
| RU2013149174A (ru) | Новое имидазооксазиновое соединение или его соль | |
| JP2015500856A5 (enExample) | ||
| AU2012361581B2 (en) | Effect potentiator for antitumor agents | |
| RU2012104700A (ru) | Азабициклосоединение и его соль | |
| CA3027498A1 (en) | Cxcr4 inhibitors and uses thereof | |
| RU2012129168A (ru) | Производные оксазина | |
| RU2010126105A (ru) | Производные пиридина, замещенные гетероциклическим кольцом и фосфоноксиметильной группой, и содержащие их противогрибковые средства | |
| JP2015503540A5 (enExample) | ||
| RS54339B1 (sr) | Novi antimalarijski agensi | |
| He et al. | Synthesis and biological evaluation of novel pyrazoline derivatives as potent anti-inflammatory agents | |
| JP2013509392A5 (enExample) | ||
| RU2002131885A (ru) | Антраниламиды и их применение в качестве лекарственных средств | |
| RU2012108423A (ru) | Ацилгуанидиновые производные с азотсодержащим циклом | |
| JP2014516070A5 (enExample) | ||
| AU2009335221A1 (en) | Toluidine sulfonamides and their use | |
| JP2013540714A5 (enExample) | ||
| CA2626767A1 (en) | Heterocyclic substituted pyridine derivatives and antifungal agent containing same | |
| JP2015500267A5 (enExample) | ||
| EP4180429A1 (en) | Pyrimidinone derivative, and preparation method therefor and use thereof against mycobacterium tuberculosis infection |