PH12014501514A1 - New azetidine derivatives, pharmaceutical compositions and uses thereof - Google Patents
New azetidine derivatives, pharmaceutical compositions and uses thereofInfo
- Publication number
- PH12014501514A1 PH12014501514A1 PH12014501514A PH12014501514A PH12014501514A1 PH 12014501514 A1 PH12014501514 A1 PH 12014501514A1 PH 12014501514 A PH12014501514 A PH 12014501514A PH 12014501514 A PH12014501514 A PH 12014501514A PH 12014501514 A1 PH12014501514 A1 PH 12014501514A1
- Authority
- PH
- Philippines
- Prior art keywords
- pharmaceutical compositions
- azetidine derivatives
- new azetidine
- new
- derivatives
- Prior art date
Links
- 150000001539 azetidines Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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- C07—ORGANIC CHEMISTRY
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- C07—ORGANIC CHEMISTRY
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
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- Pulmonology (AREA)
- Communicable Diseases (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11196170 | 2011-12-30 | ||
| PCT/EP2012/077027 WO2013098375A1 (en) | 2011-12-30 | 2012-12-28 | New azetidine derivatives, pharmaceutical compositions and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12014501514A1 true PH12014501514A1 (en) | 2014-10-08 |
Family
ID=47553036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12014501514A PH12014501514A1 (en) | 2011-12-30 | 2014-06-30 | New azetidine derivatives, pharmaceutical compositions and uses thereof |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8623860B2 (enExample) |
| EP (1) | EP2797884B1 (enExample) |
| JP (1) | JP6130399B2 (enExample) |
| KR (1) | KR20140115307A (enExample) |
| CN (1) | CN104093705A (enExample) |
| AU (1) | AU2012360797A1 (enExample) |
| BR (1) | BR112014015845A8 (enExample) |
| CA (1) | CA2861013A1 (enExample) |
| EA (1) | EA201400771A1 (enExample) |
| IL (1) | IL232914A0 (enExample) |
| MX (1) | MX2014007897A (enExample) |
| PH (1) | PH12014501514A1 (enExample) |
| WO (1) | WO2013098375A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013028886A2 (pt) | 2011-05-10 | 2016-08-09 | Gilead Sciences Inc | compostos heterocíclicos fundidos como moduladores dde canal de sódio |
| NO3175985T3 (enExample) | 2011-07-01 | 2018-04-28 | ||
| TW201837023A (zh) | 2011-07-01 | 2018-10-16 | 美商基利科學股份有限公司 | 作為離子通道調節劑之稠合雜環化合物 |
| WO2014061693A1 (ja) * | 2012-10-17 | 2014-04-24 | 塩野義製薬株式会社 | 新規非芳香族炭素環又は非芳香族複素環誘導体 |
| CN105530940A (zh) | 2013-09-12 | 2016-04-27 | 辉瑞大药厂 | 乙酰辅酶a羧化酶抑制剂用于治疗寻常痤疮的用途 |
| CN103483273B (zh) * | 2013-09-12 | 2015-11-25 | 浙江工业大学 | 6-甲基-5-氟-2,4-嘧啶二胺类化合物及其制备与应用 |
| JPWO2015056782A1 (ja) | 2013-10-17 | 2017-03-09 | 塩野義製薬株式会社 | 新規アルキレン誘導体 |
| CA2942386A1 (en) | 2014-03-13 | 2015-09-17 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing cftr activity |
| WO2015138934A1 (en) | 2014-03-13 | 2015-09-17 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing cftr activity |
| US10174014B2 (en) | 2014-06-19 | 2019-01-08 | Proteostasis Therapeutics, Inc. | Compounds, compositions, and methods for increasing CFTR activity |
| US10392378B2 (en) | 2014-12-23 | 2019-08-27 | Proteostasis Therapeutics, Inc. | Derivatives of 5-phenyl- or 5-heteroarylathiazol-2-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| MA41253A (fr) | 2014-12-23 | 2017-10-31 | Proteostasis Therapeutics Inc | Composés, compositions et procédés pour augmenter l'activité du cftr |
| US10738011B2 (en) | 2014-12-23 | 2020-08-11 | Proteostasis Therapeutics, Inc. | Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| CA2971835A1 (en) | 2014-12-23 | 2016-06-30 | Proteostasis Therapeutics, Inc. | Derivatives of 3-heteroarylisoxazol-5-carboxylic amide useful for the treatment of inter alia cystic fibrosis |
| EP3325474A1 (en) | 2015-07-24 | 2018-05-30 | Proteostasis Therapeutics, Inc. | Compounds, compositions and methods of increasing cftr activity |
| KR20250136942A (ko) | 2015-10-06 | 2025-09-16 | 프로테오스타시스 테라퓨틱스, 인크. | Cftr 조절용 화합물, 조성물, 및 방법 |
| SG11201808682XA (en) | 2016-04-07 | 2018-11-29 | Proteostasis Therapeutics Inc | Silicone atoms containing ivacaftor analogues |
| CA3028966A1 (en) | 2016-06-21 | 2017-12-28 | Proteostasis Therapeutics, Inc. | Substituted phenyl-isoxazole-carboxamide compounds and use thereof for increasing cftr activity |
| CN110776504B (zh) * | 2019-11-29 | 2021-07-30 | 扬州工业职业技术学院 | 一种苯异噁唑乙氧基环丁胺衍生物及其制备方法与应用 |
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|---|---|---|---|---|
| NZ534582A (en) | 2002-02-27 | 2006-03-31 | Pfizer Prod Inc | ACC inhibitors |
| DE102005055726A1 (de) | 2005-11-23 | 2007-08-30 | Sanofi-Aventis Deutschland Gmbh | Hydroxy-substituierte Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| AU2006331882A1 (en) | 2005-12-21 | 2007-07-05 | Schering Corporation | Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists |
| CA2654792A1 (en) * | 2006-06-12 | 2007-12-21 | Merck Frosst Canada Ltd. | Azetidine derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| WO2010043052A1 (en) | 2008-10-17 | 2010-04-22 | Merck Frosst Canada Ltd. | Azetidine derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| WO2010127212A1 (en) | 2009-04-30 | 2010-11-04 | Forest Laboratories Holdings Limited | Inhibitors of acetyl-coa carboxylase |
| NZ603777A (en) | 2010-04-27 | 2013-08-30 | Takeda Pharmaceutical | Bicyclic compound derivatives and their use as acc inhibitors. |
| SG185515A1 (en) * | 2010-05-13 | 2012-12-28 | Amgen Inc | Nitrogen heterocyclic compounds useful as pde10 inhibitors |
-
2012
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- 2012-12-28 WO PCT/EP2012/077027 patent/WO2013098375A1/en not_active Ceased
- 2012-12-28 CN CN201280068972.3A patent/CN104093705A/zh active Pending
- 2012-12-28 BR BR112014015845A patent/BR112014015845A8/pt not_active Application Discontinuation
- 2012-12-28 CA CA2861013A patent/CA2861013A1/en not_active Abandoned
- 2012-12-28 AU AU2012360797A patent/AU2012360797A1/en not_active Abandoned
- 2012-12-28 EA EA201400771A patent/EA201400771A1/ru unknown
- 2012-12-28 MX MX2014007897A patent/MX2014007897A/es unknown
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| BR112014015845A2 (pt) | 2017-06-13 |
| CN104093705A (zh) | 2014-10-08 |
| EP2797884A1 (en) | 2014-11-05 |
| JP2015506355A (ja) | 2015-03-02 |
| IL232914A0 (en) | 2014-08-03 |
| MX2014007897A (es) | 2014-09-25 |
| WO2013098375A1 (en) | 2013-07-04 |
| EP2797884B1 (en) | 2016-04-13 |
| JP6130399B2 (ja) | 2017-05-17 |
| AU2012360797A1 (en) | 2014-06-12 |
| EA201400771A1 (ru) | 2014-12-30 |
| KR20140115307A (ko) | 2014-09-30 |
| US20130172316A1 (en) | 2013-07-04 |
| US8623860B2 (en) | 2014-01-07 |
| CA2861013A1 (en) | 2013-07-04 |
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