JP2015505966A5 - - Google Patents
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- JP2015505966A5 JP2015505966A5 JP2014546147A JP2014546147A JP2015505966A5 JP 2015505966 A5 JP2015505966 A5 JP 2015505966A5 JP 2014546147 A JP2014546147 A JP 2014546147A JP 2014546147 A JP2014546147 A JP 2014546147A JP 2015505966 A5 JP2015505966 A5 JP 2015505966A5
- Authority
- JP
- Japan
- Prior art keywords
- well
- sample
- cell
- tumor cells
- circulating tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 26
- 238000000034 method Methods 0.000 claims 19
- 208000005443 Circulating Neoplastic Cells Diseases 0.000 claims 13
- 238000004458 analytical method Methods 0.000 claims 10
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 7
- 102000011782 Keratins Human genes 0.000 claims 7
- 108010076876 Keratins Proteins 0.000 claims 7
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 7
- 239000000758 substrate Substances 0.000 claims 7
- 206010028980 Neoplasm Diseases 0.000 claims 5
- 201000011510 cancer Diseases 0.000 claims 5
- 238000012512 characterization method Methods 0.000 claims 4
- 238000003384 imaging method Methods 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 3
- 238000004393 prognosis Methods 0.000 claims 3
- FWBHETKCLVMNFS-UHFFFAOYSA-N 4',6-Diamino-2-phenylindol Chemical compound C1=CC(C(=N)N)=CC=C1C1=CC2=CC=C(C(N)=N)C=C2N1 FWBHETKCLVMNFS-UHFFFAOYSA-N 0.000 claims 2
- 239000002771 cell marker Substances 0.000 claims 2
- 239000011248 coating agent Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 238000013523 data management Methods 0.000 claims 2
- 238000013500 data storage Methods 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 239000011521 glass Substances 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 230000004987 nonapoptotic effect Effects 0.000 claims 2
- 230000004043 responsiveness Effects 0.000 claims 2
- 239000002356 single layer Substances 0.000 claims 2
- 238000000116 DAPI staining Methods 0.000 claims 1
- 230000001464 adherent effect Effects 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 238000000423 cell based assay Methods 0.000 claims 1
- 239000002458 cell surface marker Substances 0.000 claims 1
- 238000009104 chemotherapy regimen Methods 0.000 claims 1
- 239000006059 cover glass Substances 0.000 claims 1
- 229940127089 cytotoxic agent Drugs 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000005284 excitation Effects 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 238000005286 illumination Methods 0.000 claims 1
- 238000011269 treatment regimen Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161568793P | 2011-12-09 | 2011-12-09 | |
| US61/568,793 | 2011-12-09 | ||
| PCT/US2012/068586 WO2013086428A1 (en) | 2011-12-09 | 2012-12-07 | Apparatus, system and method for identifying circulating tumor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015505966A JP2015505966A (ja) | 2015-02-26 |
| JP2015505966A5 true JP2015505966A5 (https=) | 2016-03-31 |
Family
ID=48574948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014546147A Pending JP2015505966A (ja) | 2011-12-09 | 2012-12-07 | 循環腫瘍細胞を特定するための装置、システム、及び方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20140329917A1 (https=) |
| EP (1) | EP2788773A4 (https=) |
| JP (1) | JP2015505966A (https=) |
| KR (1) | KR20150008842A (https=) |
| CN (1) | CN104428677A (https=) |
| AU (1) | AU2012347526A1 (https=) |
| BR (1) | BR112014013956A2 (https=) |
| CA (1) | CA2858689A1 (https=) |
| EA (1) | EA201491140A1 (https=) |
| HK (1) | HK1201916A1 (https=) |
| IL (1) | IL233007A0 (https=) |
| MX (1) | MX2014006884A (https=) |
| SG (1) | SG11201403041TA (https=) |
| WO (1) | WO2013086428A1 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1413874A1 (en) | 2002-10-16 | 2004-04-28 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
| US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| DE202010018569U1 (de) | 2009-02-18 | 2017-09-26 | Streck Inc. | Konservierung zellfreier Nukleinsäuren |
| EP3045918B1 (en) | 2009-10-21 | 2017-12-06 | The Scripps Research Institute | Method of using non-rare cells to detect rare cells |
| US9956281B2 (en) | 2011-05-04 | 2018-05-01 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| US9396532B2 (en) * | 2012-11-15 | 2016-07-19 | Siemens Healthcare Diagnostics, Inc. | Cell feature-based automatic circulating tumor cell detection |
| ES2938048T3 (es) | 2013-07-24 | 2023-04-04 | Streck Llc | Composiciones y procedimientos para estabilizar las células tumorales circulantes |
| WO2015017046A1 (en) * | 2013-07-31 | 2015-02-05 | The Regents Of The University Of California | Fluorescent imaging using a flatbed scanner |
| EP3502270B1 (en) * | 2013-10-21 | 2020-03-18 | The General Hospital Corporation | Methods relating to circulating tumor cell clusters and the treatment of cancer |
| WO2015112999A1 (en) * | 2014-01-27 | 2015-07-30 | Epic Sciences, Inc. | Detection of prostate specific membrane antigen (psma) expression on circulating tumor cells (ctc) |
| EA201691496A1 (ru) | 2014-01-27 | 2016-12-30 | Эпик Сайенсиз, Инк. | Диагностика биомаркеров рака предстательной железы с помощью циркулирующих опухолевых клеток |
| EP3100052B1 (en) * | 2014-01-30 | 2021-03-10 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for biomarkers predictive of resistance to androgen receptor (ar) targeted therapies |
| EA201691682A1 (ru) | 2014-02-21 | 2017-02-28 | Эпик Сайенсиз, Инк. | Способы анализирования редких циркулирующих в крови клеток |
| CN104062428B (zh) * | 2014-07-09 | 2016-08-17 | 郑勤 | 一种检测循环肿瘤细胞的试剂盒 |
| CN107208151A (zh) * | 2014-12-10 | 2017-09-26 | 得克萨斯州大学系统董事会 | 使用基因组特异性探针的循环肿瘤和肿瘤干细胞检测 |
| US20160178630A1 (en) * | 2014-12-18 | 2016-06-23 | Creatv Microtech, Inc. | Methods for predicting overall survival of cancer patients based on numbers of circulating tumor cells |
| WO2016121574A1 (ja) * | 2015-01-29 | 2016-08-04 | コニカミノルタ株式会社 | 相互作用する分子を有する血中細胞の同時検出方法 |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| CN113552350B (zh) * | 2015-04-21 | 2024-10-11 | 基因泰克公司 | 用于前列腺癌分析的组合物和方法 |
| CN107921277A (zh) * | 2015-05-14 | 2018-04-17 | 伊利诺伊大学理事会 | 使用循环肿瘤细胞作为生物标志物来监测癌症疗法的功效的方法 |
| WO2016207986A1 (ja) * | 2015-06-24 | 2016-12-29 | 株式会社日立製作所 | 検査システム、検査装置、及び検査方法 |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| KR102064049B1 (ko) * | 2016-07-25 | 2020-01-08 | 가부시끼가이샤 옵토니쿠스 세이미쯔 | 세포의 슬라이드 글래스 표본 제작 방법 |
| EP4656715A3 (en) | 2016-07-29 | 2026-02-25 | Streck LLC | Suspension composition for hematology analysis control |
| US20200088731A1 (en) * | 2016-12-22 | 2020-03-19 | Hitachi Chemical Company, Ltd. | Method for Detecting HER2-Positive Cancer Cells |
| US9738937B1 (en) * | 2017-03-31 | 2017-08-22 | Cellmax, Ltd. | Identifying candidate cells using image analysis |
| IT201700085439A1 (it) * | 2017-07-26 | 2019-01-26 | Tethis S P A | Metodo di immobilizzazione di campioni biologici a scopo analitico e diagnostico |
| CN115119829B (zh) | 2017-10-19 | 2024-07-12 | 斯特雷克股份有限公司 | 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物 |
| JP6485576B2 (ja) * | 2018-04-19 | 2019-03-20 | 日立化成株式会社 | 標準細胞液 |
| CN109887542A (zh) * | 2019-02-12 | 2019-06-14 | 嘉兴海云惠智医疗科技有限公司 | 一种基于云计算的肿瘤个体化基因检测智能解读系统 |
| CN110146704A (zh) * | 2019-03-28 | 2019-08-20 | 苏州举健生物科技有限公司 | 一种基于循环肿瘤细胞的用药及病理检测数据系统 |
| JP2021110664A (ja) * | 2020-01-14 | 2021-08-02 | 学校法人杏林学園 | 癌被験体の予後を予測する方法 |
| CN111323362A (zh) * | 2020-03-17 | 2020-06-23 | 宁波江丰生物信息技术有限公司 | 一种基于荧光切片的循环肿瘤细胞检测系统及检测方法 |
| CN114092934A (zh) * | 2020-07-31 | 2022-02-25 | 骏实生物科技(上海)有限公司 | 循环肿瘤细胞的分类方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3830721A1 (de) * | 1988-09-09 | 1990-03-22 | Michael Dr Menton | In labors, insbesondere in medizinischen labors, zu verwendender objekttraeger |
| CN2265982Y (zh) * | 1996-05-20 | 1997-10-29 | 中国农业大学 | 平底方槽型细胞显微操作载片 |
| US8192994B2 (en) * | 1998-02-10 | 2012-06-05 | Angros Lee H | Method of applying a biological specimen to an analytic plate |
| EP1101143A1 (en) * | 1998-08-07 | 2001-05-23 | Biogenex Laboratories | Slides with reaction zones defined by hydrophobic barriers |
| CN2377532Y (zh) * | 1999-06-10 | 2000-05-10 | 中国人民解放军第二军医大学 | 微量荧光细胞计数板 |
| US20020187485A1 (en) * | 2000-10-25 | 2002-12-12 | Jakobsen Mogens Hausteen | Open substrate platforms suitable for analysis of biomolecules |
| US7943093B2 (en) * | 2001-12-12 | 2011-05-17 | Erie Scientific Company | Cover slip |
| US20070009389A1 (en) * | 2005-07-08 | 2007-01-11 | Antti Seppo | Slide deposition chamber |
| EP1984030B1 (en) * | 2006-01-30 | 2013-05-08 | The Scripps Research Institute | Methods for detection of circulating tumor cells and methods of diagnosis of cancer in a mammalian subject |
| US8244021B2 (en) * | 2006-12-20 | 2012-08-14 | Ventana Medical Systems, Inc. | Quantitative, multispectral image analysis of tissue specimens stained with quantum dots |
| WO2008151278A1 (en) * | 2007-06-05 | 2008-12-11 | Nanopoint, Inc. | Cell tray systems and methods |
| CN201184866Y (zh) * | 2008-02-26 | 2009-01-21 | 强实贸易(上海)有限公司 | 定量细胞计数系统装置 |
| US8860938B2 (en) * | 2008-10-21 | 2014-10-14 | Chemometec A/S | Apparatus and methods for analysing fluorescent particles |
| CA2788245A1 (en) * | 2010-01-27 | 2011-08-04 | Duke University | Biomarkers for circulating tumor cells |
-
2012
- 2012-12-07 SG SG11201403041TA patent/SG11201403041TA/en unknown
- 2012-12-07 KR KR20147018924A patent/KR20150008842A/ko not_active Withdrawn
- 2012-12-07 WO PCT/US2012/068586 patent/WO2013086428A1/en not_active Ceased
- 2012-12-07 BR BR112014013956A patent/BR112014013956A2/pt not_active Application Discontinuation
- 2012-12-07 EA EA201491140A patent/EA201491140A1/ru unknown
- 2012-12-07 US US14/363,290 patent/US20140329917A1/en not_active Abandoned
- 2012-12-07 HK HK15102251.3A patent/HK1201916A1/xx unknown
- 2012-12-07 JP JP2014546147A patent/JP2015505966A/ja active Pending
- 2012-12-07 CA CA2858689A patent/CA2858689A1/en not_active Abandoned
- 2012-12-07 EP EP12855719.6A patent/EP2788773A4/en not_active Withdrawn
- 2012-12-07 MX MX2014006884A patent/MX2014006884A/es unknown
- 2012-12-07 CN CN201280069331.XA patent/CN104428677A/zh active Pending
- 2012-12-07 AU AU2012347526A patent/AU2012347526A1/en not_active Abandoned
-
2014
- 2014-06-08 IL IL233007A patent/IL233007A0/en unknown
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